| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dan Huang, Yunhui Fan, Jingjun Zhang, Qianfeng Wang, Ming Ding, Ruiqing Hou, Kewei Yu, Xiao Xiao, Yi Wu, Junfa W. Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice. Experimental neurology. 2024-04-30. PMID:38685308. |
compared to the mice housing in a standard environment, those subjected to acute ee stimulation had significantly increased alff and reho values in the bilateral somatosensory cortex (s1, s2), dorsal dentate gyrus (ddg), dorsal ca1 of hippocampus (dca1), lateral habenular nucleus (lhb), periaqueductal gray (pag), ipsilateral primary motor cortex (m1), retrosplenial cortex (rsc), parietal association cortex (pta), dorsal ca3 of hippocampus (dca3), claustrum (cl), ventral pallidum (vp), amygdala (amy), and contralateral auditory cortex (au). |
2024-04-30 |
2024-05-03 |
mouse |
| Hongren Huang, Xue Liu, Liping Wang, Feng Wan. Whole-brain connections of glutamatergic neurons in the mouse lateral habenula in both sexes. Biology of sex differences. vol 15. issue 1. 2024-04-23. PMID:38654275. |
the lateral habenula (lhb) is an epithalamus nucleus that is evolutionarily conserved and involved in various physiological functions, such as encoding value signals, integrating emotional information, and regulating related behaviors. |
2024-04-23 |
2024-04-26 |
mouse |
| In-Beom Jin, Nam-Heon Kim, Jung-Soo Ha. Emerging role of the lateral habenula in conditioned inhibition and depression. Behavioral neuroscience. 2024-04-18. PMID:38635178. |
recent research has shed light on the lateral habenula (lhb) engagement in conditioned inhibition, along with the midbrain dopaminergic neurons. |
2024-04-18 |
2024-04-20 |
Not clear |
| P Leon Brown, Heather Palacorolla, Dana E Cobb-Lewis, Thomas C Jhou, Pat McMahon, Dana Bell, Greg I Elmer, Paul D Shepar. Substantia nigra dopamine neuronal responses to habenular stimulation and foot shock are altered by lesions of the rostromedial tegmental nucleus. Neuroscience. 2024-04-18. PMID:38636897. |
dopamine (da) neurons of the substantia nigra (sn) and ventral tegmental area generally respond to aversive stimuli or the absence of expected rewards with transient inhibition of firing rates, which can be recapitulated with activation of the lateral habenula (lhb) and eliminated by lesioning the intermediating rostromedial tegmental nucleus (rmtg). |
2024-04-18 |
2024-04-21 |
rat |
| Taida Huang, Xiaonan Guo, Xiaomin Huang, Chenju Yi, Yihui Cui, Yiyan Don. Input-output specific orchestration of aversive valence in lateral habenula during stress dynamics. Journal of Zhejiang University. Science. B. 2024-04-14. PMID:38616136. |
among various regions across the brain, the lateral habenula (lhb) serves as a critical hub for processing aversive information during the dynamic process of stress accumulation, thus having been implicated in the pathogenesis of depression. |
2024-04-14 |
2024-04-17 |
Not clear |
| Lu Liu, Jie Wu, Changlin Zhang, Tong Cao, Yongli Lu, Zhi He, Zicheng L. Inhibition of endoplasmic reticulum stress attenuates morphine protracted abstinence-induced anxiety-like behaviors in the male mice. Brain research. 2024-04-11. PMID:38604556. |
(2) the endoplasmic reticulum stress-related proteins in the lateral habenula (lhb) but not in the nucleus accumbens (nac), ventral pallidum (vp), basolateral amygdala (bla) and ca1 of hippocampus was upregulated by morphine withdrawal, upregulation of endoplasmic reticulum stress-related proteins in the lateral habenula induced by morphine withdrawal was inhibited by 4-pba. |
2024-04-11 |
2024-04-14 |
mouse |
| Huihui Tan, Chengxue Du, Li Zhang, Yuan Guo, Yaxin Yang, Qingfeng Sun, Qiaojun Zhang, Libo L. Lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats. Brain research. 2024-04-08. PMID:38588847. |
the lateral habenula (lhb) projects to the ventral tegmental area (vta) and dorsal raphe nuclei (drn) that deliver dopamine (da) and serotonin (5-ht) to cortical and limbic regions such as the medial prefrontal cortex (mpfc), hippocampus and basolateral amygdala (bla). |
2024-04-08 |
2024-04-11 |
rat |
| Rixing Lin, Haruka Mitsuhashi, Laura M Fiori, Ryan Denniston, El Cherif Ibrahim, Catherine Belzung, Naguib Mechawar, Gustavo Tureck. SNORA69 is up-regulated in the lateral habenula of individuals with major depressive disorder. Scientific reports. vol 14. issue 1. 2024-04-08. PMID:38589409. |
in this study, we quantified small nucleolar rna (snorna) expression by small rna sequencing in the lateral habenula (lhb) of individuals with mdd (n = 15) and psychiatrically-healthy controls (n = 15). |
2024-04-08 |
2024-04-11 |
mouse |
| Chang Wang, Yuting Sun, Yanjie Xing, Kezhou Liu, Kedi X. Role of electrophysiological activity and interactions of lateral habenula in the development of depression-like behavior in a chronic restraint stress model. Brain research. 2024-04-05. PMID:38580047. |
there is growing evidence suggesting a strong association between the lateral habenula (lhb) and depression. |
2024-04-05 |
2024-04-10 |
Not clear |
| Kang Zhou, Lin-Chen Zhang, He Zhu, Bei Wen, Jia-Li Tang, Ping-Chuan Yuan, A-Fang Zhu, Yu-Guang Huan. A Common Neuronal Ensemble in the Lateral Habenula Regulates Ciprofol Anesthesia in Mice. Pharmaceuticals (Basel, Switzerland). vol 17. issue 3. 2024-03-28. PMID:38543149. |
recent studies have revealed that the glutamatergic neurons of the lateral habenula (lhb) play a crucial role in modulating the loc induced by propofol and sevoflurane. |
2024-03-28 |
2024-03-30 |
mouse |
| Dominik Groos, Fritjof Helmche. The lateral habenula: A hub for value-guided behavior. Cell reports. vol 43. issue 4. 2024-03-24. PMID:38522071. |
over the past two decades, studies of the lateral habenula (lhb), in particular, have identified key functions in value-guided behavior in health and disease. |
2024-03-24 |
2024-03-27 |
Not clear |
| Sarah C Simmons, William J Flerlage, Ludovic D Langlois, Ryan D Shepard, Christopher Bouslog, Emily H Thomas, Kaitlyn M Gouty, Jennifer L Sanderson, Shawn Gouty, Brian M Cox, Mark L Dell'Acqua, Fereshteh S Nugen. AKAP150-anchored PKA regulates synaptic transmission and plasticity, neuronal excitability and CRF neuromodulation in the mouse lateral habenula. Communications biology. vol 7. issue 1. 2024-03-21. PMID:38509283. |
emerging evidence also suggests that akap150 signaling may play a key role in brain's processing of rewarding/aversive experiences, however its role in the lateral habenula (lhb, as an important brain reward circuitry) is completely unknown. |
2024-03-21 |
2024-03-23 |
mouse |
| Xiaohan Tong, Jijin Wu, Ruizhe Sun, Han Li, Yingxi Hong, Xianwei Liu, Ying Sun, Chunxiao Chen, Lu Huang, Song Li. Elevated dorsal medial prefrontal cortex to lateral habenula pathway activity mediates chronic stress-induced depressive and anxiety-like behaviors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-03-14. PMID:38480908. |
one of the key downstream targets of the mpfc, the lateral habenula (lhb), is essential for chronic stress (cs)-induced depressive and anxiety-like behaviors. |
2024-03-14 |
2024-03-16 |
Not clear |
| Jessie Benedict, Robert H Cudmore, Diarra Oden, Aleah Spruell, David J Linde. The lateral habenula is required for maternal behavior in the mouse dam. bioRxiv : the preprint server for biology. 2024-02-26. PMID:38405910. |
previous work has implicated the lateral habenula (lhb), an epithalamic nucleus, as a potential intersection of parenting behavior and reward. |
2024-02-26 |
2024-02-28 |
mouse |
| Victor P Mathis, Maya Williams, Clementine Fillinger, Paul J Kenn. Networks of habenula-projecting cortical neurons regulate cocaine seeking. Science advances. vol 7. issue 45. 2024-02-14. PMID:34739312. |
the lateral habenula (lhb) serves as a “hub” to filter and propagate stress- and aversion-relevant information in the brain. |
2024-02-14 |
2024-02-16 |
mouse |
| Peihui Wu, Wenchang Li, Rongke Lv, Xin Cheng, Fan Lian, Wenbao Cai, Yubo Hu, Yanni Zeng, Bizhen Ke, Yi Chen, Zaohui Ma, Meiqi Ma, Weiping Dai, Pei Xia, Yangyang Lin, Wei-Jye Lin, Xiaojing Y. Hyperactive lateral habenula mediates the comorbidity between rheumatoid arthritis and depression-like behaviors. Brain, behavior, and immunity. 2024-02-06. PMID:38320683. |
the collagen antibody-induced arthritis (caia) mouse model of ra develops also depression-like behaviors, accompanied by hyperactivity and alterations in gene expression reflecting cerebrovascular disruption in the lateral habenula (lhb), a brain region critical for processing negative valence. |
2024-02-06 |
2024-02-09 |
mouse |
| Wanqin Tan, Yoko Ikoma, Yusuke Takahashi, Ayumu Konno, Hirokazu Hirai, Hajime Hirase, Ko Matsu. Anxiety control by astrocytes in the lateral habenula. Neuroscience research. 2024-02-04. PMID:38311032. |
the potential role of astrocytes in lateral habenula (lhb) in modulating anxiety was explored in this study. |
2024-02-04 |
2024-02-07 |
mouse |
| Dana Cobb-Lewis, Anne George, Shannon Hu, Katherine Packard, Mingyuan Song, Oliver Nguyen-Lopez, Emily Tesone, Jhanay Rowden, Julie Wang, Maya Openda. The lateral habenula integrates age and experience to promote social transitions in developing rats. bioRxiv : the preprint server for biology. 2024-01-23. PMID:38260652. |
here, we focused on the infant lateral habenula (lhb), a highly-conserved brain region at the nexus between forebrain and monoaminergic circuits. |
2024-01-23 |
2024-01-25 |
rat |
| Xiaowei Chen, Xiaofeng Liu, Shuxin Luan, Xuxin Wang, Ying Zhang, Yulei Hao, Qiang Zhang, Jiaming Zhang, Hua Zha. Optogenetic activation of the lateral habenula European archives of psychiatry and clinical neuroscience. 2024-01-18. PMID:38236282. |
optogenetic activation of the lateral habenula a number of different receptors are distributed in glutamatergic neurons of the lateral habenula (lhb). |
2024-01-18 |
2024-01-20 |
Not clear |
| Hakyun Ryu, Minseok Kim, Hoyong Park, Han Kyoung Choi, ChiHye Chun. Stress-induced translation of KCNB1 contributes to the enhanced synaptic transmission of the lateral habenula. Frontiers in cellular neuroscience. vol 17. 2024-01-09. PMID:38193032. |
the lateral habenula (lhb) is a well-established brain region involved in depressive disorders. |
2024-01-09 |
2024-01-10 |
Not clear |