| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuqi Zhang, Longyu Ma, Xueying Zhang, Lupeng Yue, Jiaxin Wang, Jie Zheng, Shuang Cui, Feng-Yu Liu, Zhiyan Wang, You Wan, Ming Y. Deep brain stimulation in the lateral habenula reverses local neuronal hyperactivity and ameliorates depression-like behaviors in rats. Neurobiology of disease. 2023-03-09. PMID:36893902. |
increasing evidence has revealed an intimate association between the lateral habenula (lhb) and major depression, and suggests that the lhb might be an effective target of dbs therapy for depression. |
2023-03-09 |
2023-08-14 |
rat |
| In-Beom Jin, Yong-Jae Jeon, Jeiwon Cho, Jung-Soo Ha. Lateral Habenula Lesions Impair the Association of a Conditioned Stimulus with the Absence of an Unconditioned Stimulus: Retardation Task. Behavioural brain research. 2023-03-02. PMID:36863460. |
recent studies have indicated that the lateral habenula (lhb) mediates the association of a conditioned stimulus (cs) with the absence of an unconditioned stimulus (us). |
2023-03-02 |
2023-08-14 |
rat |
| Elahe Amohashemi, Hojjatallah Alaei, Parham Reis. Effects of GABA Research in pharmaceutical sciences. vol 18. issue 1. 2023-02-27. PMID:36846735. |
effects of gaba the lateral habenula (lhb), a key area in the regulation of the reward system, exerts a major influence on midbrain neurons. |
2023-02-27 |
2023-08-14 |
Not clear |
| Nathan D Winters, Veronika Kondev, Niharika Loomba, Eric Delpire, Brad A Grueter, Sachin Pate. Opposing retrograde and astrocyte-dependent endocannabinoid signaling mechanisms regulate lateral habenula synaptic transmission. Cell reports. vol 42. issue 3. 2023-02-26. PMID:36842084. |
the lateral habenula (lhb) encodes aversive states, and its dysregulation is implicated in neuropsychiatric disorders, including depression. |
2023-02-26 |
2023-08-14 |
Not clear |
| Ege Kingir, Cem Sevinc, Gunes Una. Chronic oral ketamine prevents anhedonia and alters neuronal activation in the lateral habenula and nucleus accumbens in rats under chronic unpredictable mild stress. Neuropharmacology. 2023-02-22. PMID:36813161. |
cums caused a reduction of sucrose consumption and impaired spatial memory, accompanied by increased neuronal activation in the lateral habenula (lhb) and paraventricular thalamic nucleus (pvt). |
2023-02-22 |
2023-08-14 |
rat |
| Wen-Wen Zhang, Teng Chen, Shi-Yi Li, Xin-Yue Wang, Wen-Bo Liu, Yu-Quan Wang, Wen-Li Mi, Qi-Liang Mao-Ying, Yan-Qing Wang, Yu-Xia Ch. Tachykinin receptor 3 in the lateral habenula alleviates pain and anxiety comorbidity in mice. Frontiers in immunology. vol 14. 2023-02-09. PMID:36756128. |
here, the role of tachykinin receptor 3 (nk3r) in the lateral habenula (lhb) in trigeminal neuralgia and in pain-associated anxiety was systematically investigated. |
2023-02-09 |
2023-08-14 |
mouse |
| Dong-Hee Kim, Bo-Ryoung Choi, In-Beom Jin, Jin-Ah Jeon, Sang-Pil Park, Jung-Soo Ha. Chemogenetic activation of lateral habenula accelerates the extinction of the appetitive conditioned responses. Behavioral neuroscience. 2023-02-09. PMID:36757972. |
a previous study reported lateral habenula (lhb) lesions decelerated appetitive extinction. |
2023-02-09 |
2023-08-14 |
rat |
| Fang Zhou, Dan Wang, Huiming Li, Sa Wang, Xinxin Zhang, Ao Li, Tingting Tong, Haixing Zhong, Qianzi Yang, Hailong Don. Orexinergic innervations at GABAergic neurons of the lateral habenula mediates the anesthetic potency of sevoflurane. CNS neuroscience & therapeutics. 2023-02-05. PMID:36740262. |
however, the lateral habenula (lhb), as one of the orexin downstream targets, is known for its anesthesia-promoting effect. |
2023-02-05 |
2023-08-14 |
Not clear |
| Matthew V Green, David A Gallegos, Jane-Valeriane Boua, Luke C Bartelt, Arthy Narayanan, Anne E Wes. Single-nucleus transcriptional profiling of GAD2-positive neurons from mouse lateral habenula reveals distinct expression of neurotransmission- and depression-related genes. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711842. |
glutamatergic projection neurons of the lateral habenula (lhb) drive behavioral state modulation by regulating the activity of midbrain monoaminergic neurons. |
2023-01-30 |
2023-08-14 |
mouse |
| Lucas Lecourtier, Laura Durieux, Victor Mathi. Alteration of LHb function prevents the proper exploration of a novel environment. Neuroscience. 2023-01-30. PMID:36716915. |
the lateral habenula (lhb) is an epithalamic brain region viewed as a converging hub, integrating information from a large connectome and then projecting to few critical midbrain monoaminergic systems. |
2023-01-30 |
2023-08-14 |
rat |
| Zhengxiao Fan, Jiarui Chang, Yilan Liang, Hong Zhu, Chaoyi Zhang, Diyang Zheng, Junying Wang, Ying Xu, Qi-Jing Li, Hailan H. Neural mechanism underlying depressive-like state associated with social status loss. Cell. 2023-01-24. PMID:36693374. |
through the lateral hypothalamus, the rpe strongly activates the brain's anti-reward center, the lateral habenula (lhb). |
2023-01-24 |
2023-08-14 |
mouse |
| Yinhan Li, Jinjin Ren, Zhaoting Zhang, Yali Weng, Jian Zhang, Xinhui Zou, Siying Wu, Hong H. Modification and Expression of mRNA m6A in the Lateral Habenular of Rats after Long-Term Exposure to Blue Light during the Sleep Period. Genes. vol 14. issue 1. 2023-01-21. PMID:36672884. |
an early anatomical tracing study described the projection of the retina to the lateral habenula (lhb), whereas more mechanistic reports are available on multiple brain functions and neuropsychiatric disorders in the lhb, which are rarely seen in epigenetic studies, particularly n6-methyladenosine (m6a). |
2023-01-21 |
2023-08-14 |
rat |
| Fang Wang, Juen Zhang, Yuan Yuan, Ming Chen, Zilong Gao, Shulu Zhan, Chengyu Fan, Wenzhi Sun, Ji H. Salience processing by glutamatergic neurons in the ventral pallidum. Science bulletin. vol 65. issue 5. 2023-01-20. PMID:36659230. |
besides, vp glutamatergic neurons project to both the lateral habenula (lhb) and the ventral tegmental area (vta). |
2023-01-20 |
2023-08-14 |
Not clear |
| Michał Wilczkowski, Karolina Karwowska, Michal Kielbinski, Katarzyna Zajda, Kamil Pradel, Gniewosz Drwięga, Zenon Rajfur, Tomasz Blasiak, Ryszard Przewlocki, Wojciech B Soleck. Recruitment of inhibitory neuronal pathways regulating dopaminergic activity for the control of cocaine seeking. The European journal of neuroscience. 2022-12-08. PMID:36479859. |
here, we asked if optogenetic stimulation of the lateral habenula (lhb) efferents in the rostromedial tegmental nucleus (rmtg) as well as rmtg efferents in vta would reduce drug seeking. |
2022-12-08 |
2023-08-14 |
rat |
| Ying Duan, Pei-Jung Tsai, Betty Jo Salmeron, Yuzheng Hu, Hong Gu, Hanbing Lu, Jean Lud Cadet, Elliot A Stein, Yihong Yan. Compulsive drug-taking is associated with habenula-frontal cortex connectivity. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 50. 2022-12-05. PMID:36469769. |
as a critical node connecting the forebrain with the midbrain, the lateral habenula (lhb) processes negative feedback in response to aversive events and plays an essential role in value-based decision-making. |
2022-12-05 |
2023-08-14 |
rat |
| Guang-Ming Zhang, Hong-Yun Wu, Wen-Qiang Cui, Wei Pen. Multi-level variations of lateral habenula in depression: A comprehensive review of current evidence. Frontiers in psychiatry. vol 13. 2022-11-17. PMID:36386995. |
recently, the lateral habenula (lhb) has been extensively reported to undergo a series of adaptive changes at multiple levels during the depression state. |
2022-11-17 |
2023-08-14 |
Not clear |
| Hyunchan Lee, Okihide Hikosak. Lateral habenula neurons signal step-by-step changes of reward prediction. iScience. vol 25. issue 11. 2022-11-17. PMID:36388993. |
we then studied the lateral habenula (lhb), which inhibit dopamine neurons (matsumoto and hikosaka, 2007). |
2022-11-17 |
2023-08-14 |
monkey |
| Jack F Webster, Sanne Beerens, Christian Wozn. Effects of early life stress and subsequent re-exposure to stress on neuronal activity in the lateral habenula. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-11-13. PMID:36371544. |
in various animal models of depression, the lateral habenula (lhb) has been shown to become hyperactive immediately after early life stress. |
2022-11-13 |
2023-08-14 |
mouse |
| Elahe Amohashemi, Parham Reisi, Hojjatallah Alae. Involvement of AMPA receptors of lateral habenula in the expression and acquisition phases of morphine-induced place preference. Brain research. 2022-11-07. PMID:36343725. |
the lateral habenula (lhb), known as the brain structure of the epithalamic, plays the main role in depression and drug addiction. |
2022-11-07 |
2023-08-14 |
rat |
| Lujuan He, Yi Zheng, Lixuan Huang, Jingyi Ye, Yinyi Ye, Hanyue Luo, Xi Chen, Wei Yao, Jiaxu Chen, Ji-Chun Zhan. Nrf2 regulates the arginase 1 Translational psychiatry. vol 12. issue 1. 2022-11-01. PMID:36316319. |
nrf2 regulates the arginase 1 the expression of the triggering receptor on myeloid cell-2 (trem2) knockdown in microglia from the lateral habenula (lhb) reportedly induces depression-like behaviors in mice. |
2022-11-01 |
2023-08-14 |
mouse |