| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yunwei Fu, Yan Yang, Lu Huang, Xiaodan Huang, Qian Yang, Qian Tao, Jijin Wu, Kwok-Fai So, Song Lin, Ti-Fei Yuan, Chaoran Re. A visual circuit related to the habenula mediates the prevention of cocaine relapse by bright light treatment. Science bulletin. 2023-08-16. PMID:37586975. |
we found that during cocaine withdrawal, the lateral habenula (lhb) was recruited, and inhibition of the lhb via blt prevented cocaine-driven reinstatement. |
2023-08-16 |
2023-09-07 |
Not clear |
| Han Byeol Jang, DanBi Ahn, Hyung Kyu Kim, Xiaowei Guan, Yu Fan, Bae Hwan Lee, Hee Young Ki. Mediation of lateral hypothalamus orexin input to lateral habenula in the inhibitory effects of mechanical stimulation on psychomotor responses induced by cocaine. Frontiers in molecular neuroscience. vol 16. 2023-07-28. PMID:37501724. |
our previous studies have demonstrated that mechanical stimulation (ms) of the ulnar nerve produces strong inhibitory effects on cocaine addiction-like behaviors through activation of lh projection to the lateral habenula (lhb). |
2023-07-28 |
2023-08-14 |
Not clear |
| Mauro Congiu, Sarah Mondoloni, Ioannis S Zouridis, Lisa Schmors, Salvatore Lecca, Arnaud L Lalive, Kyllian Ginggen, Fei Deng, Philipp Berens, Rosa Chiara Paolicelli, Yulong Li, Andrea Burgalossi, Manuel Mamel. Plasticity of neuronal dynamics in the lateral habenula for cue-punishment associative learning. Molecular psychiatry. 2023-07-06. PMID:37414924. |
here, employing a pavlovian discrimination task in mice we investigate how neuronal populations in the lateral habenula (lhb), a subcortical nucleus whose excitation underlies negative affect, encode the association between conditioned stimuli and a punishment (unconditioned stimulus). |
2023-07-06 |
2023-08-14 |
mouse |
| Arman Hajikarim-Hamedani, Amirhossein Heidari, Mitra-Sadat Sadat-Shirazi, Sarah Mahboubi, Samira Raminfard, Solmaz Khalifeh, Mohammad-Reza Zarrindas. The role of lateral habenula NMDA receptors in tramadol-induced conditioning. Behavioural pharmacology. 2023-07-04. PMID:37401401. |
the role of the lateral habenula (lhb) as a hub for receiving and relaying signals from the limbic system to serotonergic, dopaminergic, and norepinephrinergic regions in the brainstem makes this area a critical region in the control of reward and addiction. |
2023-07-04 |
2023-08-14 |
rat |
| Xingyun Xu, Hang Zhou, Hainan Wu, Zhigang Miao, Bo Wan, Haigang Ren, Wei Ge, Guanghui Wang, Xingshun X. Tet2 acts in the lateral habenula to regulate social preference in mice. Cell reports. vol 42. issue 7. 2023-07-04. PMID:37402169. |
the lateral habenula (lhb) has been considered a moderator of social behaviors. |
2023-07-04 |
2023-08-14 |
mouse |
| Rui Chen, Xiang Xu, Xin-Yue Wang, Wen-Bin Jia, De-Shan Zhao, Na Liu, Zhen Pang, Xiao-Qing Liu, Yan Zhan. The lateral habenula nucleus regulates pruritic sensation and emotion. Molecular brain. vol 16. issue 1. 2023-06-27. PMID:37370111. |
the lateral habenula nucleus (lhb) encodes negative emotions in the epithalamus and has been implicated in pain and analgesia. |
2023-06-27 |
2023-08-14 |
Not clear |
| Daniela Calvigioni, Janos Fuzik, Pierre Le Merre, Marina Slashcheva, Felix Jung, Cantin Ortiz, Antonio Lentini, Veronika Csillag, Marta Graziano, Ifigeneia Nikolakopoulou, Moritz Weglage, Iakovos Lazaridis, Hoseok Kim, Irene Lenzi, Hyunsoo Park, Björn Reinius, Marie Carlén, Konstantinos Meleti. Esr1 Nature neuroscience. 2023-06-22. PMID:37349481. |
esr1 excitatory projections from the lateral hypothalamic area (lha) to the lateral habenula (lhb) drive aversive responses. |
2023-06-22 |
2023-08-14 |
Not clear |
| Chi Kin Ip, Jemma Rezitis, Yue Qi, Nikita Bajaj, Julia Koller, Aitak Farzi, Yan-Chuan Shi, Ramon Tasan, Lei Zhang, Herbert Herzo. Critical role of lateral habenula circuits in the control of stress-induced palatable food consumption. Neuron. 2023-06-09. PMID:37295418. |
here, we identify lateral habenula (lhb) npy1r-expressing neurons as the critical node for promoting hedonic feeding under stress, since lack of npy1r in these neurons alleviates the obesifying effects caused by combined stress and high fat feeding (hfds) in mice. |
2023-06-09 |
2023-08-14 |
mouse |
| Gen Li, Binshi Bo, Puxin Wang, Peixing Qian, Mingzhe Li, Yuyan Li, Chuanjun Tong, Kaiwei Zhang, Baogui Zhang, Tianzi Jiang, Zhifeng Liang, Xiaojie Dua. Instantaneous antidepressant effect of lateral habenula deep brain stimulation in rats studied with functional MRI. eLife. vol 12. 2023-06-01. PMID:37261976. |
we applied deep brain stimulation (dbs) to the lateral habenula (lhb) of two rat models of depression (wistar kyoto rats and lipopolysaccharide-treated rats) and observed an immediate (within seconds to minutes) alleviation of depressive-like symptoms with a high-response rate. |
2023-06-01 |
2023-08-14 |
rat |
| Saida Oubraim, Roh-Yu Shen, Samir Haj-Dahman. Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses. iScience. vol 26. issue 5. 2023-05-30. PMID:37250336. |
neuronal mapping demonstrates that oxt preferentially potentiates glutamate synapses of 5-ht neurons projecting to medial prefrontal cortex (mpfc) and depresses glutamatergic inputs to 5-ht neurons projecting to lateral habenula (lhb) and central amygdala (cea). |
2023-05-30 |
2023-08-14 |
Not clear |
| Dan Dong, Xiaofeng Liu, Lijiang Ma, Yu Lei Hao, Li Zhang, Meiying Song, Zhonggao Xu, Hua Zha. Dapagliflozin inhibits the activity of lateral habenula to alleviate diabetes mellitus-induced depressive-like behavior. Experimental neurology. 2023-05-21. PMID:37211324. |
the lateral habenula (lhb) plays an important role in the pathogenesis of depression expresses sglt2, suggesting that the lhb may mediate antidepressant effects of sglt2 inhibitors. |
2023-05-21 |
2023-08-14 |
rat |
| Han Byeol Jang, DanBi Ahn, Suchan Chang, Hyung Kyu Kim, Bong Hyo Lee, Sang Chan Kim, Scott C Steffensen, Kyle B Bills, Hubert Lee, Hee Young Ki. Activation of a hypothalamus-habenula circuit by mechanical stimulation inhibits cocaine addiction-like behaviors. Biological research. vol 56. issue 1. 2023-05-16. PMID:37194106. |
the lateral habenula (lhb), the lateral hypothalamus (lh), and the mesolimbic da system are not only reciprocally connected, but also involved in drug reward. |
2023-05-16 |
2023-08-14 |
Not clear |
| Han-Wen Gu, Guang-Fen Zhang, Pan-Miao Liu, Wei-Tong Pan, Yuan-Xiang Tao, Zhi-Qiang Zhou, Jian-Jun Yan. Contribution of activating lateral hypothalamus-lateral habenula circuit to nerve trauma-induced neuropathic pain in mice. Neurobiology of disease. 2023-05-14. PMID:37182721. |
here, we report that a projection from the lateral hypothalamus (lh) glutamatergic neurons to the lateral habenula (lhb), an excitatory lh-lhb neuronal circuit, participates in nerve injury-induced nociceptive hypersensitivity. |
2023-05-14 |
2023-08-14 |
mouse |
| Sukanya G Gakare, Rajesh R Ugal. Pharmacological evaluation of lateral habenula and rostromedial tegmental nucleus in the expression of ethanol-induced place preference. Behavioural pharmacology. vol 34. issue 4. 2023-05-12. PMID:37171461. |
recently, lateral habenula (lhb) has been shown to be engaged by both rewarding and aversive stimuli. |
2023-05-12 |
2023-08-14 |
Not clear |
| Elahe Amohashemi, Parham Reisi, Hojjatallah Alae. The role of NMDA glutamate receptors in the lateral habenula on morphine-induced conditioned place preference in rats. Synapse (New York, N.Y.). 2023-05-01. PMID:37122079. |
the lateral habenula (lhb) has received special attention due to its role in modulating motivated behavior, stress response, and rewarding and aversive stimuli through monoamine transmission. |
2023-05-01 |
2023-08-14 |
rat |
| Soo Hyun Yang, Esther Yang, Jaekwang Lee, Jin Yong Kim, Hyeijung Yoo, Hyung Sun Park, Jin Taek Jung, Dongmin Lee, Sungkun Chun, Yong Sang Jo, Gyeong Hee Pyeon, Jae-Yong Park, Hyun Woo Lee, Hyun Ki. Neural mechanism of acute stress regulation by trace aminergic signalling in the lateral habenula in male mice. Nature communications. vol 14. issue 1. 2023-04-27. PMID:37105975. |
chronic stress drives depression by excitation of the lateral habenula (lhb), which silences dopaminergic neurons in the ventral tegmental area (vta) via gabaergic neuronal projection from the rostromedial tegmental nucleus (rmtg). |
2023-04-27 |
2023-08-14 |
mouse |
| Zhiheng Ren, Jiawei Hou, Wenfu Li, Ying Tang, Molin Wang, Ruxuan Ding, Songlin Liu, Yixin Fu, Yunlin Mai, Jianxun Xia, Wanhong Zuo, Li-Hua Zhou, Jiang-Hong Ye, Rao F. LPA1 receptors in the lateral habenula regulate negative affective states associated with alcohol withdrawal. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-04-14. PMID:37059867. |
lpa receptors are widely expressed in the central nervous system, including the lateral habenula (lhb). |
2023-04-14 |
2023-08-14 |
rat |
| Zhiqiang Cui, Chao Jiang, Chunhua Hu, Ye Tian, Zhipei Ling, Jian Wang, Tengteng Fan, Hongwei Hao, Zhiyan Wang, Luming L. Safety and precision of frontal trajectory of lateral habenula deep brain stimulation surgery in treatment-resistant depression. Frontiers in neurology. vol 14. 2023-04-03. PMID:37006495. |
the lateral habenula (lhb) is a promising deep brain stimulation (dbs) target for treatment-resistant depression (trd). |
2023-04-03 |
2023-08-14 |
Not clear |
| M E Flanigan, O J Hon, S D'Ambrosio, K M Boyt, L Hassanein, M Castle, H L Haun, M M Pina, T L Kas. Subcortical serotonin 5HT Nature communications. vol 14. issue 1. 2023-03-31. PMID:37002196. |
these negative behavioral outcomes were associated with sex-specific adaptations in serotonergic signaling systems within the lateral habenula (lhb) and the bed nucleus of the stria terminalis (bnst), particularly those related to the receptor 5ht |
2023-03-31 |
2023-08-14 |
mouse |
| Mobina Alemi, Ana Raquel Pereira, Mariana Cerqueira-Nunes, Clara Monteiro, Vasco Galhardo, Helder Cardoso-Cru. Role of Glutamatergic Projections from Lateral Habenula to Ventral Tegmental Area in Inflammatory Pain-Related Spatial Working Memory Deficits. Biomedicines. vol 11. issue 3. 2023-03-29. PMID:36979799. |
the lateral habenula (lhb) and the ventral tegmental area (vta), which form interconnected circuits, have important roles in the crucial control of sensory and cognitive motifs. |
2023-03-29 |
2023-08-14 |
rat |