| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jaung-Geng Lin, Ching-Liang Hsieh, Yi-Wen Li. Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK. PloS one. vol 10. issue 6. 2016-05-02. PMID:26043006. |
both trpv1 and trpv4 protein expression levels were increased in the spinal cord (sc) of model mice, and ea at the st36 acupoint decreased overexpression. |
2016-05-02 |
2023-08-13 |
mouse |
| Jaung-Geng Lin, Ching-Liang Hsieh, Yi-Wen Li. Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK. PloS one. vol 10. issue 6. 2016-05-02. PMID:26043006. |
this study strongly suggests that drg trpv1 overexpression and perk signaling, as well as sc trpv1 and trpv4 overexpression, mediate hyperalgesia in a mouse fm pain model. |
2016-05-02 |
2023-08-13 |
mouse |
| Rebecca M Sappington, Tatiana Sidorova, Nicholas J Ward, Rohini Chakravarthy, Karen W Ho, David J Calkin. Activation of transient receptor potential vanilloid-1 (TRPV1) influences how retinal ganglion cell neurons respond to pressure-related stress. Channels (Austin, Tex.). vol 9. issue 2. 2016-02-08. PMID:25713995. |
finally, while trpv1 and trpv4 co-localize in some rgc bodies and form a protein complex in the retina, expression of their mrna is inversely related with increasing ocular pressure. |
2016-02-08 |
2023-08-13 |
mouse |
| Camilla Fusi, Serena Materazzi, Daiana Minocci, Vincenza Maio, Teresa Oranges, Daniela Massi, Romina Nassin. Transient receptor potential vanilloid 4 (TRPV4) is downregulated in keratinocytes in human non-melanoma skin cancer. The Journal of investigative dermatology. vol 134. issue 9. 2014-12-17. PMID:24643128. |
a subgroup of the transient receptor potential (trp) channels, including vanilloid 1 (trpv1), trpv2, trpv3, trpv4, and trp ankyrin 1 (trpa1), is expressed in cutaneous peptidergic somatosensory neurons, and has been found in skin non-neuronal cells, such as keratinocytes. |
2014-12-17 |
2023-08-12 |
human |
| Travis E Brown, Anda M Chirila, Benjamin R Schrank, Julie A Kaue. Loss of interneuron LTD and attenuated pyramidal cell LTP in Trpv1 and Trpv3 KO mice. Hippocampus. vol 23. issue 8. 2014-03-05. PMID:23536486. |
here we tested the role of other trpv channels in hippocampal synaptic plasticity, using hippocampal slices from trpv1, trpv3 and trpv4 knockout (ko) mice. |
2014-03-05 |
2023-08-12 |
mouse |
| Travis E Brown, Anda M Chirila, Benjamin R Schrank, Julie A Kaue. Loss of interneuron LTD and attenuated pyramidal cell LTP in Trpv1 and Trpv3 KO mice. Hippocampus. vol 23. issue 8. 2014-03-05. PMID:23536486. |
ltd at excitatory synapses on s. radiatum hippocampal interneurons was attenuated in slices from trpv3 ko mice (as well as in trpv1 ko mice as previously reported), but not in slices from trpv4 ko mice. |
2014-03-05 |
2023-08-12 |
mouse |
| M Aguilera, P Vergara, V Martíne. Environment-related adaptive changes of gut commensal microbiota do not alter colonic toll-like receptors but modulate the local expression of sensory-related systems in rats. Microbial ecology. vol 66. issue 1. 2013-12-16. PMID:23666270. |
colonic expression of tlr2, tlr4, tlr5, and tlr7, cannabinoid receptors (cb1/cb2), μ-opioid receptor (mor), transient receptor potential vanilloid (trpv1, trpv3, and trpv4), protease-activated receptor 2 (par-2), and calcitonin gene-related peptide were quantified by rt-qpcr. |
2013-12-16 |
2023-08-12 |
rat |
| Gisela Segond von Banchet, Michael K Boettger, Christian König, Yoichiro Iwakura, Rolf Bräuer, Hans-Georg Schaibl. Neuronal IL-17 receptor upregulates TRPV4 but not TRPV1 receptors in DRG neurons and mediates mechanical but not thermal hyperalgesia. Molecular and cellular neurosciences. vol 52. 2013-07-22. PMID:23147107. |
neuronal il-17 receptor upregulates trpv4 but not trpv1 receptors in drg neurons and mediates mechanical but not thermal hyperalgesia. |
2013-07-22 |
2023-08-12 |
mouse |
| I P Voronova, A A Tuzhikova, T V Kozyrev. [Thermosensitive TRP channels gene expression in hypothalamus of normal rats and rats adapted to cold]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 98. issue 9. 2013-01-22. PMID:23293814. |
for the first time in this brain region the expression of trpv3 and trpm8 genes was found, that was the evidence of the presence of trpv3 and trpm8 ion channels in the hypothalamus; it was made a comparison of the gene expression of the 6 thermosensitive ion channels (trpv1, trpv2, trpv3, trpv4, trpa1, trpm8) and found that there was rather high expression of the genes of thermosensitive ion channels activated at temperatures above 30 degrees c, while, the gene expression level of cold sensitive trpm8 and trpa1 proved to be much lower; it was found that long-term cold adaptation modified the gene expression of trpv3 ion channel. |
2013-01-22 |
2023-08-12 |
rat |
| Wei-Hsin Chen, Jason T C Tzen, Ching Liang Hsieh, Yung Hsiang Chen, Tzu-Jou Lin, Shih-Yin Chen, Yi-Wen Li. Attenuation of TRPV1 and TRPV4 Expression and Function in Mouse Inflammatory Pain Models Using Electroacupuncture. Evidence-based complementary and alternative medicine : eCAM. vol 2012. 2012-12-24. PMID:23258994. |
the protein levels of trpv1 and trpv4 in drg (dorsal root ganglion) neurons were both increased at day 4 after the initiation of inflammatory pain and were attenuated by ea, as demonstrated by immunostaining and western blot analysis. |
2012-12-24 |
2023-08-12 |
mouse |
| Sorana Ciura, Wolfgang Liedtke, Charles W Bourqu. Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 41. 2011-12-06. PMID:21994383. |
hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving trpv1 but not trpv4. |
2011-12-06 |
2023-08-12 |
mouse |
| Peter Holze. Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system. Pharmacology & therapeutics. vol 131. issue 1. 2011-10-05. PMID:21420431. |
the polymodal sensory function of trpa1, trpm5, trpm8, trpp2, trpv1, trpv3 and trpv4 enables the digestive system to survey its physical and chemical environment, which is relevant to all processes of digestion. |
2011-10-05 |
2023-08-12 |
Not clear |
| Susan M Huang, Xiaoxin Li, YinYin Yu, Juan Wang, Michael J Caterin. TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation. Molecular pain. vol 7. 2011-09-12. PMID:21586160. |
additionally, we assessed the contributions of trpv3 and trpv4 to acute heat nociception and inflammatory heat hyperalgesia during inhibition of trpv1. |
2011-09-12 |
2023-08-12 |
mouse |
| J Frederick, M E Buck, D J Matson, D N Cortrigh. Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury. Biochemical and biophysical research communications. vol 358. issue 4. 2007-08-09. PMID:17517374. |
we developed a multiplex ribonuclease protection assay (rpa) to quantify rat trpv1, trpv2, trpv3, trpv4, trpa1, and trpm8 rna levels in drg. |
2007-08-09 |
2023-08-12 |
rat |
| Paul Facer, Maria A Casula, Graham D Smith, Christopher D Benham, Iain P Chessell, Chas Bountra, Marco Sinisi, Rolfe Birch, Praveen Anan. Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy. BMC neurology. vol 7. 2007-07-10. PMID:17521436. |
differential expression of the capsaicin receptor trpv1 and related novel receptors trpv3, trpv4 and trpm8 in normal human tissues and changes in traumatic and diabetic neuropathy. |
2007-07-10 |
2023-08-12 |
human |
| Takashi Yoshida, Ryuji Inoue, Takashi Morii, Nobuaki Takahashi, Shinichiro Yamamoto, Yuji Hara, Makoto Tominaga, Shunichi Shimizu, Yoji Sato, Yasuo Mor. Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nature chemical biology. vol 2. issue 11. 2007-01-03. PMID:16998480. |
recombinant trpc1, trpc4, trpc5, trpv1, trpv3 and trpv4 of the trpc and trpv families, which are commonly classified as receptor-activated channels and thermosensor channels, induce entry of ca(2+) into cells in response to nitric oxide (no). |
2007-01-03 |
2023-08-12 |
Not clear |