| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V A Mezl, C Villemure, P M Garber, K Rakusa. Aortic stenosis produces hypertrophy of the rat heart without causing an accumulation of N1-acetylspermidine. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 66. issue 9. 1989-01-12. PMID:2973332. |
isoprenaline treatment causes cardiac hypertrophy and an accumulation of n1-acetylspermidine in the rat heart. |
1989-01-12 |
2023-08-11 |
rat |
| J M Bell, W L Whitmore, T A Slotki. Neonatal nutritional deprivation or enhancement: the cardiac-sympathetic axis and its role in cardiac growth and stress responses. Pediatric research. vol 23. issue 4. 1988-06-30. PMID:3374996. |
nevertheless, cardiac hypertrophy in response to repeated isoproterenol administration was markedly suppressed in nutritionally deprived animals, suggesting that the beta-receptor/ornithine decarboxylase pathway had become uncoupled from growth. |
1988-06-30 |
2023-08-11 |
rat |
| Q Tang, P B Taylor, R K Helbin. Catecholamine induced cardiac hypertrophy. The Canadian journal of cardiology. vol 3. issue 6. 1988-02-26. PMID:2962704. |
cardiac hypertrophy was induced in adult female wistar rats by daily subcutaneous injections of isoproterenol (0.3 mg/kg body weight). |
1988-02-26 |
2023-08-11 |
rat |
| N M Knufman, A van der Laarse, H W Vliegen, C J Brinkma. Quantification of myocardial necrosis and cardiac hypertrophy in isoproterenol-treated rats. Research communications in chemical pathology and pharmacology. vol 57. issue 1. 1987-11-25. PMID:2959998. |
administration of a single high dose or multiple low doses of isoproterenol (iso) to rats induces myocardial necrosis and cardiac hypertrophy. |
1987-11-25 |
2023-08-11 |
rat |
| M G Humphreys-Beher, G D Robinson, S Al-Zahid, C A Schneye. Neural and dietary modulation of proline-rich protein and 4 beta-galactosyltransferase biosynthesis in rat parotid glands. Archives of oral biology. vol 32. issue 8. 1987-11-24. PMID:3118859. |
maintenance of rats on a bulk diet (50 per cent inert cellulose and 50 per cent laboratory chow) before or after the removal of the submandibular-sublingual glands resulted in hypertrophy of the parotid gland, and the induction of basic proline-rich proteins in that gland with apparent molecular weights similar to those found after chronic administration of isoproterenol. |
1987-11-24 |
2023-08-11 |
rat |
| E M Blanchard, L A Mulieri, N R Alper. The effects of acute and chronic inotropic interventions on tension independent heat of rabbit papillary muscle. Basic research in cardiology. vol 82 Suppl 2. 1987-11-19. PMID:2959254. |
contrary to the working hypothesis, positive or negative inotropic effects on twitch tension caused by pressure overload hypertrophy, thyrotoxic hypertrophy, isoproterenol, and udcg115 were not accompanied by parallel changes in tih. |
1987-11-19 |
2023-08-11 |
rabbit |
| A Bergh, H Blom, J E Damber, R Henriksso. The effect of long-term variation in sympathetic activity on testicular morphology in immature rats. Andrologia. vol 19. issue 4. 1987-11-17. PMID:2821845. |
isoproterenol treatment resulted in a marked leydig cell hypertrophy but the development of the spermatogenic epithelium was unaffected compared to that in saline treated controls. |
1987-11-17 |
2023-08-11 |
rat |
| F Cuccurullo, A Mezzetti, D Lapenna, V Tomassetti, E Porreca, G Poggiopollini, M D Guglielmi, M Mancini, L Marzio, S Lenz. Mechanism of isoproterenol-induced angina pectoris in patients with obstructive hypertrophic cardiomyopathy and normal coronary arteries. The American journal of cardiology. vol 60. issue 8. 1987-10-27. PMID:3661432. |
in 14 patients with obstructive hypertrophic cardiomyopathy and angiographically normal coronary arteries, 8 with angina (group b) and 6 without (group a), the effects of intravenous isoproterenol, 2 to 4 micrograms/min, followed by intravenous propranolol, 0.2 mg/kg, were studied. |
1987-10-27 |
2023-08-11 |
Not clear |
| M G Humphreys-Beher, C A Schneyer, T Zelle. Alpha-lactalbumin acts as a bimodal regulator of rat parotid acinar cell growth. Biochemical and biophysical research communications. vol 147. issue 1. 1987-10-08. PMID:2443129. |
isoproterenol, a beta-adrenergic receptor agonist, causes hypertrophy and hyperplasia of the rat parotid gland. |
1987-10-08 |
2023-08-11 |
rat |
| M G Humphreys-Beher, C A Schneyer, T Zelle. Alpha-lactalbumin acts as a bimodal regulator of rat parotid acinar cell growth. Biochemical and biophysical research communications. vol 147. issue 1. 1987-10-08. PMID:2443129. |
alpha-lactalbumin, a specific modifier protein for 4 beta-galactosyltransferase, when given subsequent to the initiation of isoproterenol treatment and the commencement of parotid enlargement, resulted in a termination of gland hypertrophy and dna synthesis. |
1987-10-08 |
2023-08-11 |
rat |
| M G Humphreys-Beher, C A Schneyer, V J Kidd, R B Marchas. Isoproterenol-mediated parotid gland hypertrophy is inhibited by effectors of 4 beta-galactosyltransferase. The Journal of biological chemistry. vol 262. issue 24. 1987-09-30. PMID:3114249. |
chronic administration of the beta-adrenergic receptor agonist isoproterenol results in parotid gland hypertrophy and hyperplasia. |
1987-09-30 |
2023-08-11 |
cattle |
| Y Sugishita, T Yamaguchi, T Ogawa, K Iida, M Matsuda, I It. Variability of negative T wave in hypertrophic cardiomyopathy: possible role of beta-adrenergic function. Acta cardiologica. vol 42. issue 2. 1987-07-28. PMID:3496726. |
to investigate the variability and the mechanism of negative t waves in hypertrophic cardiomyopathy (hcm), especially giant negative t waves in apical hypertrophy, from view point of adrenergic function, ecg was studied by treadmill exercise test and under administrations of beta-adrenergic agonist (isoproterenol) and antagonist (propranolol) in 33 patients with hcm and negative t waves. |
1987-07-28 |
2023-08-11 |
Not clear |
| J Szabó, K Nosztray, I E Takács, J Szeg. Study of the factors influencing cardiac growth. II. Digitoxin treatment and isoproterenol-induced cardiac hypertrophy in the rat. Acta biologica Hungarica. vol 36. issue 3-4. 1987-05-06. PMID:2436403. |
isoproterenol (ipr) administered to rats in a dose of 5 mg/kg for 4 days induces cardiac hypertrophy. |
1987-05-06 |
2023-08-11 |
rat |
| T Barka, R M Gubits, H M van der Noe. Beta-adrenergic stimulation of c-fos gene expression in the mouse submandibular gland. Molecular and cellular biology. vol 6. issue 8. 1987-01-16. PMID:3023955. |
isoproterenol (ipr), a beta-adrenergic agonist, induces division of acinar cells in the parotid and submandibular glands of adult rodents and produces hyperplastic and hypertrophic enlargements of these organs. |
1987-01-16 |
2023-08-11 |
mouse |
| C Yagil, Y Naito, T Bark. Immunocytochemical localization of a developmentally regulated, isoproterenol-inducible protein (LM protein) in rat submandibular gland. The American journal of anatomy. vol 177. issue 1. 1986-12-16. PMID:3776889. |
administration of the beta-adrenergic drug isoproterenol (ipr) produces hyperplastic and hypertrophic enlargements of the submandibular gland of the rat and induces the synthesis of specific proteins in this organ. |
1986-12-16 |
2023-08-11 |
rat |
| J H Wilson, M Razav. Development of severe left ventricular outflow tract obstruction over the course of 14 years: an unusual natural history of hypertrophic obstructive cardiomyopathy. Catheterization and cardiovascular diagnosis. vol 12. issue 2. 1986-07-07. PMID:2939964. |
a patient with hypertrophic obstructive cardiomyopathy who when first seen had a normal physial examination, chest x-ray, and electrocardiogram, and no provokable gradient with isoproterenol at cardiac catheterization, was re-evaluated after 14 years. |
1986-07-07 |
2023-08-11 |
Not clear |
| P A Khairallah, M K Hanna, R C Tarazi, M E Upsher, K Yoshid. Biochemical alterations in cardiac hypertrophy. Journal of hypertension. Supplement : official journal of the International Society of Hypertension. vol 2. issue 3. 1986-06-25. PMID:6242562. |
in both two-kidney, one clip renal hypertensive rats (rhr) and spontaneously hypertensive rats (shr) with myocardial hypertrophy, inotropic responsiveness to adenylate cyclase mediated agonists, such as isoproterenol and glucagon is decreased, as is the responsiveness to phenylephrine acting via alpha 1 adrenergic receptors. |
1986-06-25 |
2023-08-12 |
rat |
| A B Jeppsson, B Waldeck, E Widmar. Further studies on the cardiomegaly induced by beta-adrenoceptor agonists. Acta pharmacologica et toxicologica. vol 58. issue 2. 1986-06-06. PMID:2871691. |
it is concluded that in doses expected to cause comparable stimulation of beta 2-adrenoceptors the unselective agonist isoprenaline is able, more than the beta 2-selective agonists terbutaline, procaterol and pirbuterol to cause cardiac hypertrophy thus indicating the involvement of beta 1-adrenoceptors. |
1986-06-06 |
2023-08-11 |
rat |
| F M Fouad, K Shimamatsu, S I Said, R C Taraz. Inotropic responsiveness in hypertensive left ventricular hypertrophy: impaired inotropic response to glucagon and vasoactive intestinal peptide in renal hypertensive rats. Journal of cardiovascular pharmacology. vol 8. issue 2. 1986-06-02. PMID:2422481. |
previous studies have shown that left ventricular (lv) hypertrophy in renal hypertensive rats (rhr) is associated with reduced responsiveness to beta-adrenergic stimulation (isoproterenol) but not to calcium or cardiac glycosides. |
1986-06-02 |
2023-08-11 |
rat |
| M Harri, P Kuusel. Is swimming exercise or cold exposure for rats? Acta physiologica Scandinavica. vol 126. issue 2. 1986-05-27. PMID:3705982. |
these included loss of body fat, cardiac hypertrophy, reduced urinary catecholamine excretion after test swimmings either in cold or warm water, increased tail-skin temperature response to isoprenaline, and a higher tail-skin temperature in response to cold. |
1986-05-27 |
2023-08-11 |
rat |