| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Hilal-Dandan, P A Khairalla. Cyclic AMP in myocytes isolated from hypertrophied rat hearts. Journal of molecular and cellular cardiology. vol 23. issue 6. 1991-12-13. PMID:1658343. |
reduced inotropic responsiveness to isoproterenol stimulation in the hypertrophied hearts of the shr and the rhr, both models of pressure overload hypertrophy, involve different biochemical alterations. |
1991-12-13 |
2023-08-11 |
rat |
| M Shimizu, O Irimajiri, T Nakano, T Mizokami, K Ogawa, J Sanjo, H Yamada, H Sasaki, Y Isoga. Effect of captopril on isoproterenol-induced myocardial ornithine decarboxylase activity. Journal of molecular and cellular cardiology. vol 23. issue 6. 1991-12-13. PMID:1719221. |
these results indicate that the renin-angiotensin system may participate in the induction of myocardial hypertrophy by isoproterenol. |
1991-12-13 |
2023-08-11 |
rat |
| T Eschenhagen, U Mende, M Nose, W Schmitz, H Scholz, A Warnholtz, J M Wüste. Isoprenaline-induced increase in mRNA levels of inhibitory G-protein alpha-subunits in rat heart. Naunyn-Schmiedeberg's archives of pharmacology. vol 343. issue 6. 1991-12-13. PMID:1834950. |
for comparison rats were treated with triiodothyronine (t3; 0.5 mg/kg.d) which induces cardiac hypertrophy like isoprenaline but has different effects on the adenylyl cyclase system. |
1991-12-13 |
2023-08-11 |
rat |
| K Iida, Y Sugishita, K Yukisada, K Fujieda, I It. Diastolic properties of hypertrophied hearts in essential hypertension: classification by left ventricular wall stress. Journal of cardiology. vol 20. issue 3. 1991-12-02. PMID:2151865. |
these results suggest that hypertensive patients with inappropriate hypertrophy have relatively diminished diastolic velocity (supernormal systolic velocity and normal diastolic velocity) before and during isoproterenol infusion, and that hypertensive patients with appropriate hypertrophy have absolutely diminished diastolic velocity during isoproterenol infusion, in spite of normal diastolic velocity before the infusion. |
1991-12-02 |
2023-08-11 |
human |
| K Prodanov, R Kolarova, L Tsakova, M Balutso. [Dynamic biochemical, metrometric and histomorphological studies in isoproterenol-induced myocardial hypertrophy and its regression in rats]. Eksperimentalna meditsina i morfologiia. vol 30. issue 1. 1991-10-09. PMID:1832104. |
isoproterenol, administered intraperitoneally in rats in a dose of 2 mg/kg of body mass for a period of 20 days, induced myocardial hypertrophy. |
1991-10-09 |
2023-08-11 |
rat |
| G Agnoletti, A F Panzali, A Cornacchiari, F De Giuli, R Ferrar. Effects of prolonged infusions of atrial natriuretic peptide and isoproterenol on the mechanical and endocrine function of isolated atria. Cardioscience. vol 1. issue 3. 1991-10-03. PMID:2151714. |
infusion of isoproterenol caused hypertrophy of the left chambers of the heart, a decrease of atrial content of atrial peptide with increased plasma levels. |
1991-10-03 |
2023-08-11 |
rat |
| C M Taquini, H Gómez Llambi, A Mazzadi, M Fontan, A Gall. Improvement of cardiac contractile response to beta-adrenergic stimulation in normal and two-kidney, one-clip hypertensive rats treated with nitrendipine. Journal of cardiovascular pharmacology. vol 17 Suppl 2. 1991-10-01. PMID:1715476. |
to evaluate the effect of nitrendipine on cardiac hypertrophy and inotropic response to isoproterenol in two-kidney, one-clip (2k,1c) renovascular hypertension, male wistar rats (n = 56) were divided into a clipped group (k) (n = 28) and a sham group (s) (n = 28). |
1991-10-01 |
2023-08-11 |
rat |
| C M Taquini, H Gómez Llambi, A Mazzadi, M Fontan, A Gall. Improvement of cardiac contractile response to beta-adrenergic stimulation in normal and two-kidney, one-clip hypertensive rats treated with nitrendipine. Journal of cardiovascular pharmacology. vol 17 Suppl 2. 1991-10-01. PMID:1715476. |
in conclusion, nitrendipine enhances the contractile response to isoproterenol and reverses the cardiac hypertrophy in the 2k, 1c model. |
1991-10-01 |
2023-08-11 |
rat |
| H Gómez Llambi, I Kuraja, A Massadi, A Gallo, M Fontan, C M Taquin. [Effect of alpha methyldopa on heart in renovascular hypertension]. Medicina. vol 50. issue 2. 1991-09-18. PMID:2151663. |
previous studies from our laboratory, have demonstrated that 21 days after unclipping the decrease in arterial pressure (ap) was followed by a regression of cardiac hypertrophy (ch) and a normalization of contractile response to isoproterenol (i) stimulation in two kidney one clip (2k1c) hypertension. |
1991-09-18 |
2023-08-11 |
rat |
| C C Wright, J Kedem, H R Weiss, E Rodriquez, J Wong, J W Mackenzie, P M Schol. Relationship between adenylate cyclase activity and regional myocardial energetics in experimental left ventricular hypertrophy. The Journal of surgical research. vol 50. issue 6. 1991-07-23. PMID:1828846. |
eleven anesthetized dogs with left ventricular hypertrophy and 11 controls were studied at rest and during 0.5 and 1.0 micrograms/kg/min isoproterenol infusion. |
1991-07-23 |
2023-08-11 |
Not clear |
| M F Allard, M F DeVenny, L K Doss, W E Grizzle, S P Bisho. Alterations in dietary sodium affect isoproterenol-induced cardiac hypertrophy. Journal of molecular and cellular cardiology. vol 22. issue 10. 1991-07-09. PMID:2151337. |
to assess the role of dietary sodium in the regional development and pathogenesis of isoproterenol (iso)-induced cardiac hypertrophy, male fischer rats (150-175g n = 65) were divided into control (c) and iso-treated (i) and three dietary sodium subgroups; low (8.7-13 meq/kg) (ls), normal (173.9 meq/kg) (ns) and high (1378 meq/kg) (hs). |
1991-07-09 |
2023-08-11 |
rat |
| M F Allard, M F DeVenny, L K Doss, W E Grizzle, S P Bisho. Alterations in dietary sodium affect isoproterenol-induced cardiac hypertrophy. Journal of molecular and cellular cardiology. vol 22. issue 10. 1991-07-09. PMID:2151337. |
these data shows that isoproterenol produces greater hypertrophy of the rv and the atria than the lvs and that dietary sodium restriction selectively decreases the degree of hypertrophy of the rv and the atria produced by iso. |
1991-07-09 |
2023-08-11 |
rat |
| G Rorive, P Carlier, N Smelten, A Zghei. Sympatholytic drugs and cardiac remodelling in human and experimental arterial hypertension. Basic research in cardiology. vol 86 Suppl 1. 1991-06-25. PMID:1827980. |
perfusion of isoprenaline in the dog may induce left ventricular hypertrophy (lvh), and this effect is suppressed by propranolol. |
1991-06-25 |
2023-08-11 |
human |
| H M Curbelo, O R Tumilasci, C F Pestarino, N H Arias, A B Houssa. Effects of isoproterenol on I131 uptake by the submaxillary glands in mice. Acta odontologica latinoamericana : AOL. vol 5. issue 1. 1991-04-24. PMID:2076165. |
the administration of isoproterenol induced marked hypertrophy in both normal and denervated submaxillary glands. |
1991-04-24 |
2023-08-11 |
mouse |
| G T Schuyler, L R Yarbroug. Changes in myosin and creatine kinase mRNA levels with cardiac hypertrophy and hypothyroidism. Basic research in cardiology. vol 85. issue 5. 1991-02-26. PMID:1703406. |
cardiac hypertrophy induced by low doses of isoproterenol produced decreases of alpha-mhc mrna levels to 70% of control values at day 3 and 50% at day 7. |
1991-02-26 |
2023-08-11 |
rat |
| M F Allard, L K Doss, S P Bisho. Verapamil does not prevent isoproterenol-induced cardiac hypertrophy. The American journal of cardiovascular pathology. vol 3. issue 2. 1991-02-13. PMID:2176088. |
to assess the role of verapamil (ver)-sensitive calcium (ca2+) channels in the regional development and pathogenesis of isoproterenol (iso)-induced cardiac hypertrophy, male fischer rats (150-175 g, n = 51) were divided into control (c) and iso-treated (i) and ver (v1, 100 mg/l drinking water; v2, 10 mg/kg ip twice daily) and no-ver subgroups. |
1991-02-13 |
2023-08-11 |
rat |
| J Szabó, K Nosztray, J Szeg. Changes in sarcolemmal adenosine triphosphatase activity and in ouabain sensitivity of rat myocardium in isoproterenol-induced cardiac hypertrophy. Polish journal of pharmacology and pharmacy. vol 41. issue 6. 1990-12-13. PMID:2562064. |
sodium, potassium-activated adenosine triphosphatase (atpase) activity and the sensitivity of rat myocardium to ouabain was studied in isoproterenol (ipr)-induced cardiac hypertrophy. |
1990-12-13 |
2023-08-11 |
rat |
| H T Chou, Y Yokota, H Fukuzak. Left ventricular reserve of the hypertrophied heart in patients with systemic hypertension and hypertrophic cardiomyopathy--relation to age and left ventricular relative wall thickness. Japanese circulation journal. vol 54. issue 4. 1990-10-18. PMID:2144601. |
to determine the effects of aging and concentric hypertrophy on the reserve of the left ventricle (lv), 36 patients with hypertension (ht), 22 with hypertrophic cardiomyopathy (hcm) and 25 age-matched normal subjects (n) were studied by isoproterenol (isp) infusion echocardiography. |
1990-10-18 |
2023-08-11 |
human |
| E Cibor, J P Dubie. [Effect of isoproterenol on left-ventricular systolic time interval in primary hypertrophic cardiomyopathy]. Folia medica Cracoviensia. vol 30. issue 3-4. 1990-10-12. PMID:2641940. |
[effect of isoproterenol on left-ventricular systolic time interval in primary hypertrophic cardiomyopathy]. |
1990-10-12 |
2023-08-11 |
human |
| E Cibor, J P Dubie. [Effect of isoproterenol on left-ventricular systolic time interval in primary hypertrophic cardiomyopathy]. Folia medica Cracoviensia. vol 30. issue 3-4. 1990-10-12. PMID:2641940. |
10 micrograms of isoproterenol in a group of 12 patients with hypertrophic cardiomyopathy. |
1990-10-12 |
2023-08-11 |
human |