| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li-Fang Zhu, Xiao-Yang Wu, Xue Liu, Liang Ma, Qi Zhang, Zi Yu, Zhi-Jiao He, Yue Ying, Zhu-Tian Zhang, Xiao-Yu Pan, Yu-Qi Cai, Ling Gong, Miao H. [Absence of BAX differentially affects astrocyte density in the mouse cortex and hippocampus]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 1. 2021-03-08. PMID:33665654. |
interestingly, a significant reduction of astrocyte density was observed in the hippocampus of bax knockout mice. |
2021-03-08 |
2023-08-13 |
mouse |
| Samantha L Hodges, Suzanne O Nolan, Lindsay A Tomac, Ilyasah D A Muhammad, Matthew S Binder, Joseph H Taube, Joaquin N Lug. Lipopolysaccharide-induced inflammation leads to acute elevations in pro-inflammatory cytokine expression in a mouse model of Fragile X syndrome. Physiology & behavior. vol 215. 2021-03-04. PMID:31838149. |
there were no differences in hippocampal protein expression between genotypes in microglia (iba1) or astrocyte (gfap) reactivity. |
2021-03-04 |
2023-08-13 |
mouse |
| Jing Wang, Gangadhara R Sareddy, Yujiao Lu, Uday P Pratap, Fulei Tang, Karah M Greene, Pornjittra L Meyre, Rajeshwar R Tekmal, Ratna K Vadlamudi, Darrell W Bran. Astrocyte-Derived Estrogen Regulates Reactive Astrogliosis and is Neuroprotective following Ischemic Brain Injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 50. 2021-03-04. PMID:33158962. |
in contrast, after gci, gfap-aro-ko mice: (1) lacked the normal elevation of astrocyte aromatase and hippocampal e2 levels; (2) had significantly attenuated reactive astrogliosis; and (3) displayed enhanced neuronal damage, microglia activation, and cognitive deficits. |
2021-03-04 |
2023-08-13 |
mouse |
| Jing Wang, Gangadhara R Sareddy, Yujiao Lu, Uday P Pratap, Fulei Tang, Karah M Greene, Pornjittra L Meyre, Rajeshwar R Tekmal, Ratna K Vadlamudi, Darrell W Bran. Astrocyte-Derived Estrogen Regulates Reactive Astrogliosis and is Neuroprotective following Ischemic Brain Injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 50. 2021-03-04. PMID:33158962. |
rna-sequencing (rna-seq) analysis revealed that the ischemic gfap-aro-ko mouse hippocampus failed to upregulate the "a2" panel of reactive astrocyte genes. |
2021-03-04 |
2023-08-13 |
mouse |
| Lulin Ma, Juan Li, Junli Zhou, Dexin Zhang, Zhi Xiao, Tian Yu, Ying Li, Song Ca. Intravenous lidocaine alleviates postherpetic neuralgia in rats via regulation of neuroinflammation of microglia and astrocytes. iScience. vol 24. issue 2. 2021-02-20. PMID:33604528. |
in addition, it reduced the activation of astrocyte but not microglia in pfc, acc, and hippocampus. |
2021-02-20 |
2023-08-13 |
rat |
| Lulin Ma, Juan Li, Junli Zhou, Dexin Zhang, Zhi Xiao, Tian Yu, Ying Li, Song Ca. Intravenous lidocaine alleviates postherpetic neuralgia in rats via regulation of neuroinflammation of microglia and astrocytes. iScience. vol 24. issue 2. 2021-02-20. PMID:33604528. |
intravenous lidocaine may relieve phn by inhibiting the activation of microglia and astrocyte in sdh or by reducing the neuroinflammation and astrocyte activation in pfc, acc, and hippocampus. |
2021-02-20 |
2023-08-13 |
rat |
| Gürsel Çalışkan, Anke Müller, Anne Albrech. Long-Term Impact of Early-Life Stress on Hippocampal Plasticity: Spotlight on Astrocytes. International journal of molecular sciences. vol 21. issue 14. 2021-02-19. PMID:32679826. |
in this review, we will summarize current findings on altered astrocyte function and hippocampal plasticity following early-life stress. |
2021-02-19 |
2023-08-13 |
Not clear |
| Vedrana Bali, Michelle S Mazei-Robiso. "Circ-it" for Stress: Role of a Novel Circular RNA in Hippocampal Astrocyte Function and Behavior. Biological psychiatry. vol 88. issue 5. 2021-02-18. PMID:32792050. |
"circ-it" for stress: role of a novel circular rna in hippocampal astrocyte function and behavior. |
2021-02-18 |
2023-08-13 |
Not clear |
| Dongliang Li, Mingming Chen, Tao Meng, Jianchun Fe. Hippocampal microglial activation triggers a neurotoxic-specific astrocyte response and mediates etomidate-induced long-term synaptic inhibition. Journal of neuroinflammation. vol 17. issue 1. 2021-02-10. PMID:32264970. |
hippocampal microglial activation triggers a neurotoxic-specific astrocyte response and mediates etomidate-induced long-term synaptic inhibition. |
2021-02-10 |
2023-08-13 |
Not clear |
| Rodrigo G Mira, Matías Lira, Rodrigo A Quintanilla, Waldo Cerp. Alcohol consumption during adolescence alters the hippocampal response to traumatic brain injury. Biochemical and biophysical research communications. vol 528. issue 3. 2021-02-08. PMID:32505350. |
we found that alcohol binge drinking induced by the "drinking in the dark" (did) paradigm increases oxidative damage and astrocyte activation in the hippocampus of adolescent mice. |
2021-02-08 |
2023-08-13 |
mouse |
| Kati L Healey, Sandra Kibble, Sierra Hodges, Kathryn J Reissner, Anze Testen, Tiffany A Wills, Shawn K Acheson, Benjamin M Siemsen, John A McFaddin, Michael D Scofield, H Scott Swartzwelde. Enduring alterations in hippocampal astrocytesynaptic proximity following adolescent alcohol exposure: reversal by gabapentin. Neural regeneration research. vol 15. issue 8. 2021-01-24. PMID:31997814. |
we utilized astrocyte-specific, membrane restricted viral labeling paired with immunohistochemistry to perform confocal single cell astrocyte imaging, three-dimensional reconstruction, and quantification of astrocyte morphology in hippocampal area ca1 from adult rats after aie. |
2021-01-24 |
2023-08-13 |
human |
| Yujiao Lu, Gangadhara R Sareddy, Jing Wang, Quanguang Zhang, Fu-Lei Tang, Uday P Pratap, Rajeshwar R Tekmal, Ratna K Vadlamudi, Darrell W Bran. Neuron-Derived Estrogen Is Critical for Astrocyte Activation and Neuroprotection of the Ischemic Brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 38. 2021-01-15. PMID:32817249. |
we demonstrated that ovariectomized female fbn-aro-ko mice exhibited significantly attenuated astrocyte activation, astrocytic aromatization, and decreased hippocampal e2 levels compared with flox mice. |
2021-01-15 |
2023-08-13 |
mouse |
| Yue Zhu, Mengqiu Liu, Cheng Cao, Suchen Qu, Jiani Zheng, Ziqiang Zhu, Zhichun Chen, Zhikang Wang, Zhenhua Zhu, Fei Huang, Jin-Ao Dua. Dendrobium officinale flos increases neurotrophic factor expression in the hippocampus of chronic unpredictable mild stress-exposed mice and in astrocyte primary culture and potentiates NGF-induced neuronal differentiation in PC12 cells. Phytotherapy research : PTR. 2021-01-13. PMID:33438327. |
dendrobium officinale flos increases neurotrophic factor expression in the hippocampus of chronic unpredictable mild stress-exposed mice and in astrocyte primary culture and potentiates ngf-induced neuronal differentiation in pc12 cells. |
2021-01-13 |
2023-08-13 |
mouse |
| Zhilan Peng, Cai Zhang, Ling Yan, Yongping Zhang, Zhiyou Yang, Jiajia Wang, Cai Son. EPA is More Effective than DHA to Improve Depression-Like Behavior, Glia Cell Dysfunction and Hippcampal Apoptosis Signaling in a Chronic Stress-Induced Rat Model of Depression. International journal of molecular sciences. vol 21. issue 5. 2020-12-01. PMID:32150824. |
after epa or dha feeding, depression-like behavior, brain n-3/n-6 pufas profile, serum corticosterone and cholesterol concentration, hippocampal neurotransmitters, microglial and astrocyte related function, as well as neuronal apoptosis and survival signaling pathways were studied. |
2020-12-01 |
2023-08-13 |
rat |
| Huimin Kong, Huaili Wang, Zhihong Zhuo, Zhenbiao Li, Peichao Tian, Jing Wu, Jian Liu, Zheng Chen, Jiyao Zhang, Qiang Lu. Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy. Laboratory investigation; a journal of technical methods and pathology. vol 100. issue 9. 2020-11-23. PMID:32461588. |
inhibition of mir-181a-5p protected the hippocampus against epilepsy, including hippocampal insults, neuronal apoptosis, astrocyte and microglia activation, neuroinflammation, oxidative stress, mitochondrial function, and cognitive dysfunction. |
2020-11-23 |
2023-08-13 |
rat |
| Angela Ts Wyse, Cassiana Siebert, Larissa D Bobermin, Tiago M Dos Santos, André Quincozes-Santo. Changes in Inflammatory Response, Redox Status and Na Neurotoxicity research. vol 37. issue 2. 2020-11-12. PMID:31773642. |
since menopause may be associated with brain dysfunction, in the present study, we evaluated anti- and proinflammatory cytokine release in cortical and hippocampal astrocyte cultures obtained from adult female wistar rats subjected to ovariectomy, a known experimental model of menopause. |
2020-11-12 |
2023-08-13 |
rat |
| Jude Prah, Ali Winters, Kiran Chaudhari, Jessica Hersh, Ran Liu, Shao-Hua Yan. Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress. Brain research. vol 1723. 2020-10-27. PMID:31425677. |
the neuroprotective effect of cs and its role on cell metabolism were determined in primary astrocyte prepared from the cortex of postnatal day 0-2 c57bl/6 pups and a hippocampal ht-22 cell line using calcein am and mtt cell viability assay, flow cytometry, seahorse extracellular flux analysis, and metabolism assay kits. |
2020-10-27 |
2023-08-13 |
human |
| Cheryl Clarkson, Roy M Smeal, Meredith G Hasenoehrl, John A White, Maria E Rubio, Karen S Wilco. Ultrastructural and functional changes at the tripartite synapse during epileptogenesis in a model of temporal lobe epilepsy. Experimental neurology. vol 326. 2020-10-27. PMID:31935368. |
focusing on ultrastructural properties of the tripartite synapse in the ca1 region of hippocampus we found increased astrocyte ensheathment around both the presynaptic and postsynaptic elements, reduced synaptic ampa receptor subunit and perisynaptic astrocyte glt-1 expression, and increased number of docked vesicles at the presynaptic terminal. |
2020-10-27 |
2023-08-13 |
rat |
| Maryam Anzabi, Maryam Ardalan, Nina K Iversen, Ali H Rafati, Brian Hansen, Leif Østergaar. Hippocampal Atrophy Following Subarachnoid Hemorrhage Correlates with Disruption of Astrocyte Morphology and Capillary Coverage by AQP4. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:29445328. |
hippocampal atrophy following subarachnoid hemorrhage correlates with disruption of astrocyte morphology and capillary coverage by aqp4. |
2020-10-01 |
2023-08-13 |
mouse |
| Maryam Anzabi, Maryam Ardalan, Nina K Iversen, Ali H Rafati, Brian Hansen, Leif Østergaar. Hippocampal Atrophy Following Subarachnoid Hemorrhage Correlates with Disruption of Astrocyte Morphology and Capillary Coverage by AQP4. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:29445328. |
glial fibrillary acid protein (gfap) immunostained hippocampal sections were examined by stereological techniques to detect differences in astrocyte morphology, and global spatial sampling method was used to quantify the length density of aquaporin-4 (aqp4) positive capillaries. |
2020-10-01 |
2023-08-13 |
mouse |