| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tim J Sargeant, Darren J Day, Eli M Mrkusich, Darren F Foo, John H Mille. Mu opioid receptors are expressed on radial glia but not migrating neuroblasts in the late embryonic mouse brain. Brain research. vol 1175. 2008-01-25. PMID:17888889. |
in contrast to the ventricular neuroepithelia, the proliferative external granule layer of the embryonic cerebellum did not express mor protein, although the purkinje cell layer did. |
2008-01-25 |
2023-08-12 |
mouse |
| Yonghong Zhu, Cleo C L Lee, W P Lam, Maria S M Wai, John A Rudd, David T Ye. Cell death in the Purkinje cells of the cerebellum of senescence accelerated mouse (SAMP(8)). Biogerontology. vol 8. issue 5. 2008-01-08. PMID:17415677. |
taken together, the data suggests that the aging samp(8) strain displays differential purkinje cell death in the medial cerebellum and that some of the dying cells are likely to be catecholaminergic. |
2008-01-08 |
2023-08-12 |
mouse |
| Victor Z Han, Yueping Zhang, Curtis C Bell, Christian Hanse. Synaptic plasticity and calcium signaling in Purkinje cells of the central cerebellar lobes of mormyrid fish. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 49. 2007-12-27. PMID:18057208. |
climbing fiber (cf)-evoked calcium transients play a key role in plasticity at parallel fiber (pf) to purkinje cell synapses in the mammalian cerebellum. |
2007-12-27 |
2023-08-12 |
Not clear |
| Nobuhiko Ohno, Nobuo Terada, Sei Saitoh, Shinichi Ohn. Extracellular space in mouse cerebellar cortex revealed by in vivo cryotechnique. The Journal of comparative neurology. vol 505. issue 3. 2007-12-12. PMID:17879272. |
in molecular and purkinje cell layers of the mouse cerebellum prepared with ivcr, considerably large extracellular spaces (ecs) were detected among cellular profiles and synaptic clefts. |
2007-12-12 |
2023-08-12 |
mouse |
| Tomomi Sanagi, Takeshi Yabe, Haruki Yamad. Changes in pigment epithelium-derived factor expression following kainic acid induced cerebellar lesion in rat. Neuroscience letters. vol 424. issue 1. 2007-11-20. PMID:17709187. |
in normal rat cerebellum, pedf protein and mrna were mostly confined and co-localized with calbindin-positive cells in the purkinje cell layer of the cerebellum, but not with glial fibrillary acidic protein (gfap)-, 2', 3'-cyclic nucleotide 3'-phosphodiesterase (cnpase)-, and isolectin b4-positive cells. |
2007-11-20 |
2023-08-12 |
rat |
| Suehiro Sakaguch. Molecular biology of prion protein and its first homologous protein. The journal of medical investigation : JMI. vol 54. issue 3-4. 2007-11-08. PMID:17878669. |
interestingly, it was recently shown that the first identified prp-like protein, termed prplp/doppel (dpl), is neurotoxic in the absence of prp(c), causing purkinje cell degeneration in the cerebellum of mice. |
2007-11-08 |
2023-08-12 |
mouse |
| Mario Cabraja, Jörg Bäurl. Vestibular ganglion neurons survive hair cell defects in jerker, shaker, and Varitint-waddler mutants and downregulate calretinin expression. The Journal of comparative neurology. vol 504. issue 4. 2007-11-06. PMID:17663432. |
in the present study the volume of the vg, the size and total number of bns, and the number of bns expressing the calcium-binding protein calretinin (calr) were quantified stereologically in the cerebellar mutants purkinje cell degeneration (pcd/pcd), weaver (wv/wv), and lurcher (lc/+), and in the vestibular mutants jerker (je/je), shaker-1 (sh/sh), and varitint-waddler (va/+). |
2007-11-06 |
2023-08-12 |
mouse |
| Roger Kalla, Stefan Glasauer, Ulrich Büttner, Thomas Brandt, Michael Strup. 4-aminopyridine restores vertical and horizontal neural integrator function in downbeat nystagmus. Brain : a journal of neurology. vol 130. issue Pt 9. 2007-11-01. PMID:17664175. |
our results thus show that 4-ap was a successful treatment option in the majority of dbn patients, possibly by increasing purkinje cell excitability in the cerebellar flocculi. |
2007-11-01 |
2023-08-12 |
human |
| Mohamed B Abou-Donia, Wasiuddin A Khan, Anjelika M Dechkovskaia, Larry B Goldstein, Sarah L Bullman, Ali Abdel-Rahma. In utero exposure to nicotine and chlorpyrifos alone, and in combination produces persistent sensorimotor deficits and Purkinje neuron loss in the cerebellum of adult offspring rats. Archives of toxicology. vol 80. issue 9. 2007-10-29. PMID:16482470. |
in utero exposure to nicotine and chlorpyrifos alone, and in combination produces persistent sensorimotor deficits and purkinje neuron loss in the cerebellum of adult offspring rats. |
2007-10-29 |
2023-08-12 |
human |
| Eugene Park, Jinglu Ai, Andrew J Bake. Cerebellar injury: clinical relevance and potential in traumatic brain injury research. Progress in brain research. vol 161. 2007-10-25. PMID:17618988. |
data suggest that the cerebellum is susceptible to selective purkinje cell loss as well as white matter dysfunction. |
2007-10-25 |
2023-08-12 |
Not clear |
| Wolfgang M Schmidt, Cornelia Kraus, Harald Höger, Sonja Hochmeister, Felicitas Oberndorfer, Manuela Branka, Sonja Bingemann, Hans Lassmann, Markus Müller, Lúcia Inês Macedo-Souza, Mariz Vainzof, Mayana Zatz, André Reis, Reginald E Bittne. Mutation in the Scyl1 gene encoding amino-terminal kinase-like protein causes a recessive form of spinocerebellar neurodegeneration. EMBO reports. vol 8. issue 7. 2007-10-23. PMID:17571074. |
we show that the pathology of mdf comprises cerebellar atrophy, purkinje cell loss and optic nerve atrophy, and therefore defines a new animal model for neurodegenerative diseases with cerebellar involvement in humans. |
2007-10-23 |
2023-08-12 |
mouse |
| G L Krauss, M Z Koubeiss. Cerebellar and thalamic stimulation treatment for epilepsy. Acta neurochirurgica. Supplement. vol 97. issue Pt 2. 2007-09-26. PMID:17691323. |
the sole output of the cerebellum is inhibitory purkinje cell projections to deep cerebellar nuclei in the brainstem. |
2007-09-26 |
2023-08-12 |
Not clear |
| T S Jokinen, C Rusbridge, F Steffen, R Viitmaa, P Syrjä, A De Lahunta, M Snellman, S Cizinauska. Cerebellar cortical abiotrophy in Lagotto Romagnolo dogs. The Journal of small animal practice. vol 48. issue 8. 2007-09-25. PMID:17490444. |
the first dog had an atypical lesion in the cerebellar cortex with depletion of cerebellar granular cell layer and sparing of the purkinje cell layer. |
2007-09-25 |
2023-08-12 |
dog |
| Yangu Zhao, Kin-Ming Kwan, Christina M Mailloux, Woon-Kyu Lee, Alexander Grinberg, Wolfgang Wurst, Richard R Behringer, Heiner Westpha. LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 32. 2007-09-20. PMID:17664423. |
lim-homeodomain proteins lhx1 and lhx5, and their cofactor ldb1, control purkinje cell differentiation in the developing cerebellum. |
2007-09-20 |
2023-08-12 |
mouse |
| Yangu Zhao, Kin-Ming Kwan, Christina M Mailloux, Woon-Kyu Lee, Alexander Grinberg, Wolfgang Wurst, Richard R Behringer, Heiner Westpha. LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 32. 2007-09-20. PMID:17664423. |
our studies thus provide evidence that these transcription regulators are essential for controlling purkinje cell differentiation in the developing mammalian cerebellum. |
2007-09-20 |
2023-08-12 |
mouse |
| Jean-Bernard Dietrich, Marie-Pierre Arpin-Bott, Dany Kao, Sylvie Dirrig-Grosch, Dominique Aunis, Jean Zwille. Cocaine induces the expression of homer 1b/c, homer 3a/b, and hsp 27 proteins in rat cerebellum. Synapse (New York, N.Y.). vol 61. issue 8. 2007-09-12. PMID:17455232. |
since we found that homer 3a/b colocalized with the mglur1 receptor in purkinje cells, the data suggest that the long homer isoforms are involved in the cocaine-induced neuroplasticity that takes place in the cerebellum, by reshaping postsynaptic densities in purkinje cell dendrites. |
2007-09-12 |
2023-08-12 |
rat |
| Li E Cheng, Jiangyang Zhang, Randall R Ree. The transcription factor Zfp423/OAZ is required for cerebellar development and CNS midline patterning. Developmental biology. vol 307. issue 1. 2007-09-10. PMID:17524391. |
characterization of postnatal cerebellar development shows defects in purkinje cell differentiation and granule cell proliferation. |
2007-09-10 |
2023-08-12 |
mouse |
| Jane Yip, Jean-Jacques Soghomonian, Gene J Blat. Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications. Acta neuropathologica. vol 113. issue 5. 2007-08-31. PMID:17235515. |
the results indicate that gad67 mrna level was reduced by 40% in the autistic group (p < 0.0001; two-tailed t test), suggesting that reduced purkinje cell gaba input to the cerebellar nuclei potentially disrupts cerebellar output to higher association cortices affecting motor and/or cognitive function. |
2007-08-31 |
2023-08-12 |
Not clear |
| In-Jeoung Baek, Dong-Suk Seo, Jung-Min Yon, Se-Ra Lee, Yan Jin, Sang Soep Nahm, Jae-Hwang Jeong, Young-Kug Choo, Jong-Koo Kang, Beom Jun Lee, Young Won Yun, Sang-Yoon Na. Tissue expression and cellular localization of phospholipid hydroperoxide glutathione peroxidase (PHGPx) mRNA in male mice. Journal of molecular histology. vol 38. issue 3. 2007-08-28. PMID:17503194. |
the signal was also expressed in the molecular layer, purkinje cell layer, and white matter of cerebellum, the pituicytes of neurohypophysis, the parafollicular cells and follicular basement membrane of thyroid, the exocrine portion of pancreas, the tubular epithelium of kidney, the smooth muscle cells of arteries, and the red pulp of spleen. |
2007-08-28 |
2023-08-12 |
mouse |
| Masahiko Tanak. [Mechanisms for dendritic morphogenesis of cerebellar purkinje cells: role of receptor-type protein tyrosine phosphatase zeta]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 27. issue 3. 2007-08-28. PMID:17633525. |
ptpzeta and pleiotrophin, a ligand of ptpzeta, are distributed around purkinje cell dendrites during postnatal cerebellar development. |
2007-08-28 |
2023-08-12 |
Not clear |