| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adam O Hebb, Kari Hebb, Arun C Ramachandran, Ivar Mende. Glial cell line-derived neurotrophic factor-supplemented hibernation of fetal ventral mesencephalic neurons for transplantation in Parkinson disease: long-term storage. Journal of neurosurgery. vol 98. issue 5. 2003-06-04. PMID:12744369. |
transplantation of fetal dopaminergic tissue is being investigated in animal models and clinical trials for its potential as a treatment for advanced parkinson disease. |
2003-06-04 |
2023-08-12 |
human |
| T Nakahara, T Kuroki, E Ohta, T Kajihata, H Yamada, M Yamanaka, K Hashimoto, T Tsutsumi, M Hirano, H Uchimur. Effect of the neurotoxic dose of methamphetamine on gene expression of parkin and Pael-receptors in rat striatum. Parkinsonism & related disorders. vol 9. issue 4. 2003-04-16. PMID:12618056. |
taken together with our previous report, dopaminergic modulation of the expression of parkin and pael-r genes in the nigro-striatal pathway may have significant implication for pathophysiology and treatment of parkinson disease. |
2003-04-16 |
2023-08-12 |
rat |
| Takahiro Sasaki, Takahiro Amano, Jun Hashimoto, Yoshiaki Itoh, Kazuhiro Muramatsu, Atsushi Kubo, Yasuo Fukuuch. [SPECT imaging using [123I]beta-CIT and [123I]IBF in extrapyramidal diseases]. No to shinkei = Brain and nerve. vol 55. issue 1. 2003-04-11. PMID:12649900. |
imaging of dopaminergic function is useful in the investigation of patients with parkinson disease (ipd) and other extrapyramidal diseases. |
2003-04-11 |
2023-08-12 |
human |
| V Sossi, J E Holden, R de la Fuente-Fernandez, T J Ruth, A J Stoess. Effect of dopamine loss and the metabolite 3-O-methyl-[18F]fluoro-dopa on the relation between the 18F-fluorodopa tissue input uptake rate constant Kocc and the [18F]fluorodopa plasma input uptake rate constant Ki. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 23. issue 3. 2003-04-08. PMID:12621305. |
parkinson disease is characterized by the loss of dopaminergic neurons, thus decreasing the system's ability to produce and store dopamine (da). |
2003-04-08 |
2023-08-12 |
Not clear |
| Yoshitsugu Oiwa, Rosario Sanchez-Pernaute, Judith Harvey-White, Krys S Bankiewic. Progressive and extensive dopaminergic degeneration induced by convection-enhanced delivery of 6-hydroxydopamine into the rat striatum: a novel rodent model of Parkinson disease. Journal of neurosurgery. vol 98. issue 1. 2003-02-12. PMID:12546362. |
progressive and extensive dopaminergic degeneration induced by convection-enhanced delivery of 6-hydroxydopamine into the rat striatum: a novel rodent model of parkinson disease. |
2003-02-12 |
2023-08-12 |
rat |
| Wei-Dong Le, Pingyi Xu, Joseph Jankovic, Hong Jiang, Stanley H Appel, Roy G Smith, Demetrios K Vassilati. Mutations in NR4A2 associated with familial Parkinson disease. Nature genetics. vol 33. issue 1. 2003-01-28. PMID:12496759. |
these data suggest that mutations in nr4a2 can cause dopaminergic dysfunction, associated with parkinson disease. |
2003-01-28 |
2023-08-12 |
Not clear |
| Helen Petrovitch, G Webster Ross, Robert D Abbott, Wayne T Sanderson, Dan S Sharp, Caroline M Tanner, Kamal H Masaki, Patricia L Blanchette, Jordan S Popper, Daniel Foley, Lenore Launer, Lon R Whit. Plantation work and risk of Parkinson disease in a population-based longitudinal study. Archives of neurology. vol 59. issue 11. 2002-12-16. PMID:12433267. |
parkinson disease (pd) has an unknown cause; however, convincing evidence is emerging that indicates pesticides can selectively injure the dopaminergic system in laboratory animals. |
2002-12-16 |
2023-08-12 |
Not clear |
| Felix Javier Jiménez-Jiménez, Youssef Sayed, Miguel Angel García-Soldevilla, Beatriz Barcenill. Possible zoophilia associated with dopaminergic therapy in Parkinson disease. The Annals of pharmacotherapy. vol 36. issue 7-8. 2002-11-26. PMID:12086551. |
possible zoophilia associated with dopaminergic therapy in parkinson disease. |
2002-11-26 |
2023-08-12 |
Not clear |
| Felix Javier Jiménez-Jiménez, Youssef Sayed, Miguel Angel García-Soldevilla, Beatriz Barcenill. Possible zoophilia associated with dopaminergic therapy in Parkinson disease. The Annals of pharmacotherapy. vol 36. issue 7-8. 2002-11-26. PMID:12086551. |
to report a patient with parkinson disease (pd) who developed zoophilia as a possible complication of dopaminergic therapy. |
2002-11-26 |
2023-08-12 |
Not clear |
| Guangyu Gu, Patricio E Reyes, Gregory T Golden, Randall L Woltjer, Christine Hulette, Thomas J Montine, Jing Zhan. Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders. Journal of neuropathology and experimental neurology. vol 61. issue 7. 2002-08-07. PMID:12125742. |
inhibition of mitochondrial respiratory chain function may contribute to dopaminergic neurodegeneration in the substantia nigra (sn) of patients with parkinson disease (pd). |
2002-08-07 |
2023-08-12 |
Not clear |
| Padraig E O'Suilleabhain, Richard B Dewe. Contributions of dopaminergic drugs and disease severity to daytime sleepiness in Parkinson disease. Archives of neurology. vol 59. issue 6. 2002-07-01. PMID:12056935. |
contributions of dopaminergic drugs and disease severity to daytime sleepiness in parkinson disease. |
2002-07-01 |
2023-08-12 |
Not clear |
| Jin Xu, Shyan-Yuan Kao, Frank J S Lee, Weihong Song, Lee-Way Jin, Bruce A Yankne. Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease. Nature medicine. vol 8. issue 6. 2002-06-26. PMID:12042811. |
the mechanism by which dopaminergic neurons are selectively lost in parkinson disease (pd) is unknown. |
2002-06-26 |
2023-08-12 |
human |
| Horst Przuntek, Stefan Bittkau, Harald Bliesath, Ulrich Büttner, Gerd Fuchs, Joachim Glass, Harald Haller, Thomas Klockgether, Peter Kraus, Lutz Lachenmayer, Dieter Müller, Thomas Müller, Bernhard Rathay, Jörg Sgonina, Volker Steinijans, Elemer Teshmar, Gudrun Ulm, Dieter Vol. Budipine provides additional benefit in patients with Parkinson disease receiving a stable optimum dopaminergic drug regimen. Archives of neurology. vol 59. issue 5. 2002-06-07. PMID:12020263. |
budipine provides additional benefit in patients with parkinson disease receiving a stable optimum dopaminergic drug regimen. |
2002-06-07 |
2023-08-12 |
Not clear |
| Maria-Joao Ribeiro, Marie Vidailhet, Christian Loc'h, Corinne Dupel, Jean Paul Nguyen, Michel Ponchant, Frédéric Dollé, Marc Peschanski, Philippe Hantraye, Pierre Cesaro, Yves Samson, Philippe Rem. Dopaminergic function and dopamine transporter binding assessed with positron emission tomography in Parkinson disease. Archives of neurology. vol 59. issue 4. 2002-04-19. PMID:11939892. |
dopaminergic function and dopamine transporter binding assessed with positron emission tomography in parkinson disease. |
2002-04-19 |
2023-08-12 |
Not clear |
| Ivar Mendez, Alain Dagher, Murray Hong, Paula Gaudet, Swarna Weerasinghe, Vivian McAlister, David King, Jacques Desrosiers, Sultan Darvesh, Tanya Acorn, Harold Robertso. Simultaneous intrastriatal and intranigral fetal dopaminergic grafts in patients with Parkinson disease: a pilot study. Report of three cases. Journal of neurosurgery. vol 96. issue 3. 2002-03-29. PMID:11883846. |
simultaneous intrastriatal and intranigral fetal dopaminergic grafts in patients with parkinson disease: a pilot study. |
2002-03-29 |
2023-08-12 |
Not clear |
| William G Ondo, Kevin Dat Vuong, Joseph Jankovi. Exploring the relationship between Parkinson disease and restless legs syndrome. Archives of neurology. vol 59. issue 3. 2002-03-27. PMID:11890847. |
restless legs syndrome (rls) and parkinson disease (pd) are common neurological conditions that respond to dopaminergic therapy. |
2002-03-27 |
2023-08-12 |
Not clear |
| D Włodarek, W Pakszys, M Barli. [Helicobacter pylori--does it only cause gastroduodenal disease?]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 11. issue 65. 2002-03-14. PMID:11852823. |
the direct influence of h. pylori infection on parkinson disease is not known but the following relations are suggested: h. pylori may produce toxins that damage substantia nigra in brain; possible cross reaction of h. pylori antibodies with dopaminergic neurons; indirect influence of antacids containing aluminium used to alleviate the symptoms of ulcers. |
2002-03-14 |
2023-08-12 |
human |
| K K Chung, Y Zhang, K L Lim, Y Tanaka, H Huang, J Gao, C A Ross, V L Dawson, T M Dawso. Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nature medicine. vol 7. issue 10. 2001-11-01. PMID:11590439. |
parkinson disease is a common neurodegenerative disorder characterized by the loss of dopaminergic neurons and the presence of intracytoplasmic-ubiquitinated inclusions (lewy bodies). |
2001-11-01 |
2023-08-12 |
Not clear |
| E Cubo, J M Gracies, R Benabou, C W Olanow, R Raman, S Leurgans, C G Goet. Early morning off-medication dyskinesias, dystonia, and choreic subtypes. Archives of neurology. vol 58. issue 9. 2001-10-04. PMID:11559308. |
abnormal involuntary movements (dyskinesias) are common in patients with parkinson disease (pd) as a consequence of the disease and dopaminergic replacement therapy. |
2001-10-04 |
2023-08-12 |
Not clear |
| R Sánchez-Pernaute, L Studer, K S Bankiewicz, E O Major, R D McKa. In vitro generation and transplantation of precursor-derived human dopamine neurons. Journal of neuroscience research. vol 65. issue 4. 2001-09-13. PMID:11494363. |
the successful clinical application of cns precursor technology in parkinson disease will depend on the efficient in vitro generation of human dopaminergic neurons. |
2001-09-13 |
2023-08-12 |
human |