| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Hagell, P Brundi. Cell survival and clinical outcome following intrastriatal transplantation in Parkinson disease. Journal of neuropathology and experimental neurology. vol 60. issue 8. 2001-08-16. PMID:11487048. |
intrastriatal transplantation of embryonic dopaminergic neurons is currently explored as a restorative cell therapy for parkinson disease (pd). |
2001-08-16 |
2023-08-12 |
human |
| P Hartvig, M Bergström, B Långströ. Use of positron emission tomography in analysing receptor function in vivo. Toxicology letters. vol 120. issue 1-3. 2001-05-17. PMID:11323182. |
long-term effects of different toxins on dopamine receptor function have been evaluated with pet as well as the influence of parkinson disease medication on pre- and postsynaptic dopaminergic receptor function over the course of the disease. |
2001-05-17 |
2023-08-12 |
Not clear |
| C G Goetz, P F Burke, S Leurgans, E Berry-Kravis, L M Blasucci, R Raman, L Zho. Genetic variation analysis in parkinson disease patients with and without hallucinations: case-control study. Archives of neurology. vol 58. issue 2. 2001-03-29. PMID:11176958. |
visual hallucinations in parkinson disease (pd) occur in approximately one third of patients treated long-term with dopaminergic medications. |
2001-03-29 |
2023-08-12 |
Not clear |
| . Pramipexole vs levodopa as initial treatment for Parkinson disease: A randomized controlled trial. Parkinson Study Group. JAMA. vol 284. issue 15. 2000-10-26. PMID:11035889. |
pramipexole and levodopa both ameliorate the motor symptoms of early parkinson disease (pd), but no controlled studies have compared long-term outcomes after initiating dopaminergic therapy with pramipexole vs levodopa. |
2000-10-26 |
2023-08-12 |
Not clear |
| F Yantiri, J K Anderse. The role of iron in Parkinson disease and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity. IUBMB life. vol 48. issue 2. 2000-05-25. PMID:10794588. |
parkinson disease (pd) involves the specific degeneration of dopaminergic neurons of the pars compacta of the substantia nigra. |
2000-05-25 |
2023-08-12 |
Not clear |
| J O Rinne, R Portin, H Ruottinen, E Nurmi, J Bergman, M Haaparanta, O Soli. Cognitive impairment and the brain dopaminergic system in Parkinson disease: [18F]fluorodopa positron emission tomographic study. Archives of neurology. vol 57. issue 4. 2000-04-27. PMID:10768619. |
cognitive impairment and the brain dopaminergic system in parkinson disease: [18f]fluorodopa positron emission tomographic study. |
2000-04-27 |
2023-08-12 |
Not clear |
| J O Rinne, R Portin, H Ruottinen, E Nurmi, J Bergman, M Haaparanta, O Soli. Cognitive impairment and the brain dopaminergic system in Parkinson disease: [18F]fluorodopa positron emission tomographic study. Archives of neurology. vol 57. issue 4. 2000-04-27. PMID:10768619. |
to investigate the role of the brain dopaminergic system in cognitive impairment in patients with parkinson disease (pd). |
2000-04-27 |
2023-08-12 |
Not clear |
| J Zhang, D G Graham, T J Montine, Y S H. Enhanced N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in mice deficient in CuZn-superoxide dismutase or glutathione peroxidase. Journal of neuropathology and experimental neurology. vol 59. issue 1. 2000-04-07. PMID:10744035. |
administration of n-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to mammals causes damage to the nigrostriatal dopaminergic pathway similar to that observed in parkinson disease (pd). |
2000-04-07 |
2023-08-12 |
mouse |
| D Koziorowski, J Jaszta. [Factors which can play important role in pathogenesis of Parkinson disease]. Neurologia i neurochirurgia polska. vol 33. issue 4. 2000-02-02. PMID:10612105. |
degeneration of dopaminergic neurons that project from substantia nigra to striatum is the primary mechanism that causes parkinson disease (pd). |
2000-02-02 |
2023-08-12 |
Not clear |
| G T Liberatore, V Jackson-Lewis, S Vukosavic, A S Mandir, M Vila, W G McAuliffe, V L Dawson, T M Dawson, S Przedborsk. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nature medicine. vol 5. issue 12. 1999-12-29. PMID:10581083. |
inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the mptp model of parkinson disease. |
1999-12-29 |
2023-08-12 |
mouse |
| G T Liberatore, V Jackson-Lewis, S Vukosavic, A S Mandir, M Vila, W G McAuliffe, V L Dawson, T M Dawson, S Przedborsk. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nature medicine. vol 5. issue 12. 1999-12-29. PMID:10581083. |
mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) damages dopaminergic neurons as seen in parkinson disease. |
1999-12-29 |
2023-08-12 |
mouse |
| F Grandas, M L Galian. [Pramipexol: a new dopaminergic agonist for the treatment of Parkinson disease]. Neurologia (Barcelona, Spain). vol 14. issue 5. 1999-10-28. PMID:10377723. |
[pramipexol: a new dopaminergic agonist for the treatment of parkinson disease]. |
1999-10-28 |
2023-08-12 |
Not clear |
| W D Le, D B Rowe, J Jankovic, W Xie, S H Appe. Effects of cerebrospinal fluid from patients with Parkinson disease on dopaminergic cells. Archives of neurology. vol 56. issue 2. 1999-03-04. PMID:10025424. |
effects of cerebrospinal fluid from patients with parkinson disease on dopaminergic cells. |
1999-03-04 |
2023-08-12 |
Not clear |
| C Soubrouillard, C Lombardo, O Rascol, B Bruguerolle, O Bli. [Central dopaminergic D1 agonists and treatment of Parkinson disease]. Therapie. vol 52. issue 6. 1998-09-28. PMID:9734104. |
[central dopaminergic d1 agonists and treatment of parkinson disease]. |
1998-09-28 |
2023-08-12 |
Not clear |
| K D Sethi, C F O'Brien, J P Hammerstad, C H Adler, T L Davis, R L Taylor, J Sanchez-Ramos, J M Bertoni, R A Hause. Ropinirole for the treatment of early Parkinson disease: a 12-month experience. Ropinirole Study Group. Archives of neurology. vol 55. issue 9. 1998-09-25. PMID:9740115. |
to evaluate ropinirole hydrochloride as dopaminergic monotherapy in patients with early parkinson disease. |
1998-09-25 |
2023-08-12 |
Not clear |
| A C Jones, Y Yamamura, L Almasy, S Bohlega, B Elibol, J Hubble, S Kuzuhara, M Uchida, T Yanagi, D E Weeks, T G Nygaar. Autosomal recessive juvenile parkinsonism maps to 6q25.2-q27 in four ethnic groups: detailed genetic mapping of the linked region. American journal of human genetics. vol 63. issue 1. 1998-08-13. PMID:9634534. |
parkinson disease (pd) is a common neurodegenerative condition associated with degeneration of dopaminergic neurons in the zona compacta of the substantia nigra. |
1998-08-13 |
2023-08-12 |
Not clear |
| A Bilang-Bleuel, F Revah, P Colin, I Locquet, J J Robert, J Mallet, P Horello. Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 16. 1997-09-08. PMID:9238061. |
gdnf has both protective and restorative effects on the nigro-striatal dopaminergic (da) system in animal models of parkinson disease. |
1997-09-08 |
2023-08-12 |
rat |
| S Hunot, B Brugg, D Ricard, P P Michel, M P Muriel, M Ruberg, B A Faucheux, Y Agid, E C Hirsc. Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 14. 1997-08-05. PMID:9207126. |
nuclear translocation of nf-kappab is increased in dopaminergic neurons of patients with parkinson disease. |
1997-08-05 |
2023-08-12 |
human |
| S Hunot, B Brugg, D Ricard, P P Michel, M P Muriel, M Ruberg, B A Faucheux, Y Agid, E C Hirsc. Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 14. 1997-08-05. PMID:9207126. |
evidence from postmortem studies suggest an involvement of oxidative stress in the degeneration of dopaminergic neurons in parkinson disease (pd) that have recently been shown to die by apoptosis, but the relationship between oxidative stress and apoptosis has not yet been elucidated. |
1997-08-05 |
2023-08-12 |
human |
| E Bertrand, W Lechowicz, G M Szpak, J Dymeck. [Morphometric assessment of lesions in the dopaminergic nigrostriatal system in Parkinson disease]. Neurologia i neurochirurgia polska. vol 30. issue 5. 1997-05-12. PMID:9148173. |
[morphometric assessment of lesions in the dopaminergic nigrostriatal system in parkinson disease]. |
1997-05-12 |
2023-08-12 |
human |