| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer C Andrews, François D Roy, Richard B Stein, Fang Ba, Tejas Sanka. Effects of Deep Brain Stimulation and Dopaminergic Medication on Excitatory and Inhibitory Spinal Pathways in Parkinson Disease. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. vol 38. issue 4. 2021-07-16. PMID:32501952. |
effects of deep brain stimulation and dopaminergic medication on excitatory and inhibitory spinal pathways in parkinson disease. |
2021-07-16 |
2023-08-13 |
Not clear |
| Jeong Won Lee, Yoo Sung Song, Hyeyun Kim, Bon D Ku, Won Woo Le. Methodological considerations of evaluating the rate of presynaptic dopaminergic denervation in Parkinson disease with radiotracers: Analysis of the PPMI data. Medicine. vol 100. issue 26. 2021-07-07. PMID:34190190. |
methodological considerations of evaluating the rate of presynaptic dopaminergic denervation in parkinson disease with radiotracers: analysis of the ppmi data. |
2021-07-07 |
2023-08-13 |
Not clear |
| Jeong Won Lee, Yoo Sung Song, Hyeyun Kim, Bon D Ku, Won Woo Le. Methodological considerations of evaluating the rate of presynaptic dopaminergic denervation in Parkinson disease with radiotracers: Analysis of the PPMI data. Medicine. vol 100. issue 26. 2021-07-07. PMID:34190190. |
many previous studies have estimated the rate of dopaminergic denervation in parkinson disease (pd) via imaging studies. |
2021-07-07 |
2023-08-13 |
Not clear |
| Qiankun Lv, Zhen Zhong, Binbin Hu, Si Yan, Yufang Yan, Junjun Zhang, Ting Shi, Lijuan Jiang, Wen Li, Wei Huan. MicroRNA-3473b regulates the expression of TREM2/ULK1 and inhibits autophagy in inflammatory pathogenesis of Parkinson disease. Journal of neurochemistry. vol 157. issue 3. 2021-06-21. PMID:33448372. |
parkinson disease (pd) is a neurodegenerative disease characterized by selective loss of dopaminergic (da) neurons in the midbrain. |
2021-06-21 |
2023-08-13 |
mouse |
| Jenifer S Calvo, Neha V Mulpuri, Alex Dao, Nabeeha K Qazi, Gabriele Melon. Membrane insertion exacerbates the α-Synuclein-Cu(II) dopamine oxidase activity: Metallothionein-3 targets and silences all α-synuclein-Cu(II) complexes. Free radical biology & medicine. vol 158. 2021-06-18. PMID:32712192. |
copper binding to α-synuclein (α-syn), the major component of intracellular lewy body inclusions in substantia nigra dopaminergic neurons, potentiate its toxic redox-reactivity and plays a detrimental role in the etiology of parkinson disease (pd). |
2021-06-18 |
2023-08-13 |
Not clear |
| Miguel A Labrador-Espinosa, Michel J Grothe, Daniel Macías-García, Silvia Jesús, Astrid Adarmes-Gómez, Laura Muñoz-Delgado, Paula Fernández-Rodríguez, Juan Francisco Martín-Rodríguez, Ismael Huertas, David García-Solís, Pablo Mi. Levodopa-Induced Dyskinesia in Parkinson Disease Specifically Associates With Dopaminergic Depletion in Sensorimotor-Related Functional Subregions of the Striatum. Clinical nuclear medicine. vol 46. issue 6. 2021-05-20. PMID:33782308. |
levodopa-induced dyskinesia in parkinson disease specifically associates with dopaminergic depletion in sensorimotor-related functional subregions of the striatum. |
2021-05-20 |
2023-08-13 |
Not clear |
| Miguel A Labrador-Espinosa, Michel J Grothe, Daniel Macías-García, Silvia Jesús, Astrid Adarmes-Gómez, Laura Muñoz-Delgado, Paula Fernández-Rodríguez, Juan Francisco Martín-Rodríguez, Ismael Huertas, David García-Solís, Pablo Mi. Levodopa-Induced Dyskinesia in Parkinson Disease Specifically Associates With Dopaminergic Depletion in Sensorimotor-Related Functional Subregions of the Striatum. Clinical nuclear medicine. vol 46. issue 6. 2021-05-20. PMID:33782308. |
to determine whether the development of levodopa-induced dyskinesia (lid) in parkinson disease (pd) specifically relates to dopaminergic depletion in sensorimotor-related subregions of the striatum. |
2021-05-20 |
2023-08-13 |
Not clear |
| Chengxiao Ma, Wen Zhang, Maohong Ca. Role of the Peripheral Nervous System in PD Pathology, Diagnosis, and Treatment. Frontiers in neuroscience. vol 15. 2021-05-18. PMID:33994915. |
studies on parkinson disease (pd) have mostly focused on the central nervous system-specifically, on the loss of mesencephalic dopaminergic neurons and associated motor dysfunction. |
2021-05-18 |
2023-08-13 |
Not clear |
| Chang-Ki Oh, Young Ki Choi, Ih-Yeon Hwang, Yeon Uk Ko, In Kwon Chung, Nuri Yun, Young J O. RING-finger protein 166 plays a novel pro-apoptotic role in neurotoxin-induced neurodegeneration via ubiquitination of XIAP. Cell death & disease. vol 11. issue 10. 2021-05-17. PMID:33130818. |
the dopaminergic neurotoxin, 6-hydroxydopamine (6-ohda), has been widely utilized to establish experimental models of parkinson disease and to reveal the critical molecules and pathway underlying neuronal death. |
2021-05-17 |
2023-08-13 |
Not clear |
| Eve Privman Champaloux, Nathan Donelson, Poojan Pyakurel, Danielle Wolin, Leah Ostendorf, Madelaine Denno, Ryan Borman, Chris Burke, Jonah C Short-Miller, Maria R Yoder, Jeffrey M Copeland, Subhabrata Sanyal, B Jill Vento. Ring Finger Protein 11 (RNF11) Modulates Dopamine Release in Drosophila. Neuroscience. vol 452. 2021-05-14. PMID:33176188. |
recent work indicates a role for ring finger protein 11 (rnf11) in parkinson disease (pd) pathology, which involves the loss of dopaminergic neurons. |
2021-05-14 |
2023-08-13 |
drosophila_melanogaster |
| Frank S Fa. Ractopamine residue in meat might protect people from Parkinson disease. Medical hypotheses. vol 145. 2021-05-14. PMID:33223323. |
intracytoplasmic lewy body composing of phosphorylated α-synuclein in dopaminergic neuronal cells has been recognized as the characteristic pathologic change and believed to be the cause of neuronal cell loss in parkinson disease. |
2021-05-14 |
2023-08-13 |
cattle |
| Li-Ping Liang, Ruth Fulton, Erica L Bradshaw-Pierce, Jennifer Pearson-Smith, Brian J Day, Manisha Pate. Optimization of Lipophilic Metalloporphyrins Modifies Disease Outcomes in a Rat Model of Parkinsonism. The Journal of pharmacology and experimental therapeutics. vol 377. issue 1. 2021-05-14. PMID:33500265. |
both compounds significantly attenuated dopamine depletion, cytokine production, microglial activation, dopaminergic neuronal loss, oxidative/nitrative stress indices, and behavioral abnormality in a parkinson disease rat model. |
2021-05-14 |
2023-08-13 |
mouse |
| Carlos A Sanchez-Catasus, Nicolaas I Bohnen, Fang-Cheng Yeh, Nicholas D'Cruz, Prabesh Kanel, Martijn L T M Mülle. Dopaminergic Nigrostriatal Connectivity in Early Parkinson Disease: In Vivo Neuroimaging Study of Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 62. issue 4. 2021-05-11. PMID:32859707. |
dopaminergic nigrostriatal connectivity in early parkinson disease: in vivo neuroimaging study of previous histopathologic and animal studies have shown axonal impairment and loss of connectivity of the nigrostriatal pathway in parkinson disease (pd). |
2021-05-11 |
2023-08-13 |
human |
| Yuri Inose, Yasuhiko Izumi, Yuki Takada-Takatori, Akinori Akaike, Yutaka Koyama, Shuji Kaneko, Toshiaki Kum. Protective effects of Nrf2-ARE activator on dopaminergic neuronal loss in Parkinson disease model mice: Possible involvement of heme oxygenase-1. Neuroscience letters. vol 736. 2021-04-30. PMID:32712353. |
protective effects of nrf2-are activator on dopaminergic neuronal loss in parkinson disease model mice: possible involvement of heme oxygenase-1. |
2021-04-30 |
2023-08-13 |
mouse |
| Yuri Inose, Yasuhiko Izumi, Yuki Takada-Takatori, Akinori Akaike, Yutaka Koyama, Shuji Kaneko, Toshiaki Kum. Protective effects of Nrf2-ARE activator on dopaminergic neuronal loss in Parkinson disease model mice: Possible involvement of heme oxygenase-1. Neuroscience letters. vol 736. 2021-04-30. PMID:32712353. |
parkinson disease (pd) is a neurodegenerative disorder characterized by a selective loss of dopaminergic neurons in the substantia nigra, and oxidative stress is thought to contribute to this pathogenesis. |
2021-04-30 |
2023-08-13 |
mouse |
| Akihiro Yamaguchi, Kei-Ichi Ishikawa, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Shinji Saiki, Taku Hatano, Akio Mori, Yutaka Oji, Ayami Okuzumi, Yuanzhe Li, Manabu Funayama, Yuzuru Imai, Nobutaka Hattori, Wado Akamats. Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease. Stem cell reports. vol 14. issue 6. 2021-04-19. PMID:32470327. |
parkinson disease (pd) is a neurodegenerative disorder caused by the progressive loss of midbrain dopaminergic neurons, and mitochondrial dysfunction is involved in its pathogenesis. |
2021-04-19 |
2023-08-13 |
drosophila_melanogaster |
| Wenhao Li, Han Gao, Wentao L. Effects of Combined Bushen Zhichan Recipe and Levodopa in a Rodent Model of Parkinson Disease: Potential Mechanisms. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-04-14. PMID:32555131. |
conclusions our results indicate that levodopa combined with bushen zhichan recipe significantly improves behavior and protects dopaminergic neurons in a rodent parkinson disease model, and suggest that the mechanism involves the decrease of excitatory amino acid toxicity and the increase in the expression of eaat1. |
2021-04-14 |
2023-08-13 |
rat |
| Sahar Avazzadeh, Jara Maria Baena, Cameron Keighron, Yajaira Feller-Sanchez, Leo R Quinla. Modelling Parkinson's Disease: iPSCs towards Better Understanding of Human Pathology. Brain sciences. vol 11. issue 3. 2021-04-13. PMID:33799491. |
the underlying cause of parkinson disease is degeneration of dopaminergic neurons. |
2021-04-13 |
2023-08-13 |
human |
| Zhaohui Liu, Hoi-Hung Cheun. Stem Cell-Based Therapies for Parkinson Disease. International journal of molecular sciences. vol 21. issue 21. 2021-03-29. PMID:33137927. |
parkinson disease (pd) is a neurological movement disorder resulting primarily from damage to and degeneration of the nigrostriatal dopaminergic pathway. |
2021-03-29 |
2023-08-13 |
Not clear |
| Taylor A Gee, Nathan C Weintraub, Dong Lu, Caroline E Phelps, Edita Navratilova, Michael L Heien, Frank Porrec. A pain-induced tonic hypodopaminergic state augments phasic dopamine release in the nucleus accumbens. Pain. vol 161. issue 10. 2021-03-19. PMID:32453137. |
enhanced phasic dopamine neurotransmission resulting from salient stimuli may contribute to increased impulsivity and cognitive deficits often observed in conditions associated with decreased dopaminergic tone, including parkinson disease and chronic pain. |
2021-03-19 |
2023-08-13 |
rat |