| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alphonso Wilson, Asia Filatov, Mishah Azhar, Marc Swerdloff, Sameea Husain Wilso. Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female. Cureus. vol 12. issue 7. 2020-09-28. PMID:32789046. |
we present an unusual case of acute oculogyric crisis in a 74-year-old woman with long-standing parkinson disease following exposure to the second-generation neuroleptic ziprasidone, which has dopaminergic (d2) and serotoninergic (5-ht2a) receptor blocking effects and is used for severe delusions and psychosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Alagudurai Krishnamoorthy, Murugan Sevanan, Sugumar Mani, Mangayarkarasi Balu, Sravani Balaji, Ramajayan . Chrysin restores MPTP induced neuroinflammation, oxidative stress and neurotrophic factors in an acute Parkinson's disease mouse model. Neuroscience letters. vol 709. 2020-09-24. PMID:31325581. |
parkinson disease occurs due to the depletion of dopaminergic neurons in brain resulting in decreased dopamine level and abnormal protein aggregation. |
2020-09-24 |
2023-08-13 |
mouse |
| Ledia F Hernandez, Ignacio Obeso, Rui M Costa, Peter Redgrave, Jose A Obes. Dopaminergic Vulnerability in Parkinson Disease: The Cost of Humans' Habitual Performance. Trends in neurosciences. vol 42. issue 6. 2020-09-21. PMID:31053241. |
dopaminergic vulnerability in parkinson disease: the cost of humans' habitual performance. |
2020-09-21 |
2023-08-13 |
human |
| Stéphanie Pain, Julie Deguil, Jeremie Belin, Pauline Barraud, Stéphanie Ragot, Jean-Luc Houet. Regulation of Protein Synthesis and Apoptosis in Lymphocytes of Parkinson Patients: The Effect of Dopaminergic Treatment. Neuro-degenerative diseases. vol 19. issue 5-6. 2020-09-17. PMID:32146463. |
parkinson disease (pd) is a neurodegenerative disorder characterized by progressive degeneration of the dopaminergic neurons in the substantia nigra, presumably due to increased apoptosis. |
2020-09-17 |
2023-08-13 |
Not clear |
| Mar Carmona-Abellan, Ivan Martínez-Valbuena, Carla DiCaudo, Irene Marcilla, Maria Rosario Luqui. Cardiac sympathetic innervation in the MPTP non-human primate model of Parkinson disease. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 29. issue 4. 2020-08-28. PMID:31338635. |
systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) induces degeneration of dopaminergic neurons and reproduces the motor features of parkinson disease (pd); however, the effect of mptp on extranigral structures has been poorly studied. |
2020-08-28 |
2023-08-13 |
monkey |
| Viviana Lo Buono, Rosanna Palmeri, Giuseppe Stroscio, Francesco Corallo, Giuseppe Di Lorenzo, Chiara Sorbera, Rosella Ciurleo, Vincenzo Cimino, Placido Bramanti, Silvia Marino, Lilla Bonann. The effect on deep brain stimulation of subthalamic nucleus and dopaminergic treatment in Parkinson disease. Medicine. vol 99. issue 32. 2020-08-24. PMID:32769905. |
the effect on deep brain stimulation of subthalamic nucleus and dopaminergic treatment in parkinson disease. |
2020-08-24 |
2023-08-13 |
Not clear |
| Miquel Vila, Ariadna Laguna, Iria Carballo-Carbaja. Intracellular crowding by age-dependent neuromelanin accumulation disrupts neuronal proteostasis and triggers Parkinson disease pathology. Autophagy. vol 15. issue 11. 2020-08-06. PMID:31480882. |
in parkinson disease (pd), there is a preferential degeneration of neurons that contain the dark-brown cytoplasmic pigment neuromelanin, in particular dopaminergic neurons of the substantia nigra (sn), the loss of which leads to the typical motor symptoms of the disease and constitutes the cardinal pathological diagnostic criterion for pd. |
2020-08-06 |
2023-08-13 |
Not clear |
| Delphine Charvin, Rossella Medori, Robert A Hauser, Olivier Rasco. Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs. Nature reviews. Drug discovery. vol 17. issue 11. 2020-05-11. PMID:30310231. |
therapeutic strategies for parkinson disease: beyond dopaminergic drugs. |
2020-05-11 |
2023-08-13 |
Not clear |
| Neha Prakash, Chelsea Caspell-Garcia, Christopher Coffey, Andrew Siderowf, Caroline M Tanner, Karl Kieburtz, Brit Mollenhauer, Douglas Galasko, Kalpana Merchant, Tatiana Foroud, Lana M Chahine, Daniel Weintraub, Cindy Casaceli, Ray Dorsey, Renee Wilson, Margaret Herzog, Nichole Daegele, Vanessa Arnedo, Mark Frasier, Todd Sherer, Ken Marek, Samuel Frank, Danna Jennings, Tanya Simun. Feasibility and safety of lumbar puncture in the Parkinson's disease research participants: Parkinson's Progression Marker Initiative (PPMI). Parkinsonism & related disorders. vol 62. 2020-04-28. PMID:30738748. |
to determine the feasibility, safety and tolerability of lumbar punctures (lps) in research participants with early parkinson disease (pd), subjects without evidence of dopaminergic deficiency (swedds) and healthy volunteers (hc). |
2020-04-28 |
2023-08-13 |
human |
| Ankur Butala, Melissa Shepard, Greg Ponton. Neuropsychiatric aspects of Parkinson disease psychopharmacology: Insights from circuit dynamics. Handbook of clinical neurology. vol 165. 2020-04-17. PMID:31727232. |
parkinson disease (pd) is a neurodegenerative disorder with a complex pathophysiology characterized by the progressive loss of dopaminergic neurons within the substantia nigra. |
2020-04-17 |
2023-08-13 |
Not clear |
| Stéphanie Pain, Jackie Vergote, Zuhal Gulhan, Sylvie Bodard, Sylvie Chalon, Afsaneh Gaillar. Inflammatory process in Parkinson disease: neuroprotection by neuropeptide Y. Fundamental & clinical pharmacology. vol 33. issue 5. 2020-04-07. PMID:30866091. |
inflammatory process in parkinson disease: neuroprotection by neuropeptide y. parkinson's disease (pd) is characterized by the degeneration of dopaminergic neurons in the nigro-striatal pathway. |
2020-04-07 |
2023-08-13 |
rat |
| A R Bonilla-Porras, M Jimenez-Del-Rio, C Velez-Pard. N-acetyl-cysteine blunts 6-hydroxydopamine- and L-buthionine-sulfoximine-induced apoptosis in human mesenchymal stromal cells. Molecular biology reports. vol 46. issue 4. 2020-02-14. PMID:31147858. |
parkinson disease (pd) is characterized by the loss of dopaminergic (daergic) neurons linked to environmental toxicants that cause oxidative stress (os). |
2020-02-14 |
2023-08-13 |
human |
| Myung Jun Lee, Kyoungjune Pak, Jong Hun Kim, Yun Joong Kim, Jeehee Yoon, Jinwoo Lee, Chul Hyoung Lyoo, Hyung Jun Park, Jae-Hyeok Lee, Na-Yeon Jun. Effect of polygenic load on striatal dopaminergic deterioration in Parkinson disease. Neurology. vol 93. issue 7. 2020-01-28. PMID:31289143. |
effect of polygenic load on striatal dopaminergic deterioration in parkinson disease. |
2020-01-28 |
2023-08-13 |
Not clear |
| Myung Jun Lee, Kyoungjune Pak, Jong Hun Kim, Yun Joong Kim, Jeehee Yoon, Jinwoo Lee, Chul Hyoung Lyoo, Hyung Jun Park, Jae-Hyeok Lee, Na-Yeon Jun. Effect of polygenic load on striatal dopaminergic deterioration in Parkinson disease. Neurology. vol 93. issue 7. 2020-01-28. PMID:31289143. |
to investigate the effect of polygenic load on the progression of striatal dopaminergic dysfunction in patients with parkinson disease (pd). |
2020-01-28 |
2023-08-13 |
Not clear |
| Shang-Rung Hwang, Sheng-Wei Hwang, Jin-Cherng Chen, Juen-Haur Hwan. Association of periodic limb movements during sleep and Parkinson disease: A retrospective clinical study. Medicine. vol 98. issue 51. 2020-01-06. PMID:31861016. |
both of periodic limb movements during sleep (plms) and parkinson disease (pd) were related with dopaminergic system dysfunction. |
2020-01-06 |
2023-08-13 |
human |
| P.-P. Michel, E.-C. Hirsch, Y. Agi. [Parkinson's disease: cell death mechanisms] Revue neurologique. vol 158. issue 122. 2019-11-20. PMID:12690312. |
[parkinson's disease: cell death mechanisms] parkinson disease is a neurodegenerative disorder of aging characterized by a selective and progressive loss of dopaminergic neurons within the substantia nigra. |
2019-11-20 |
2023-08-12 |
Not clear |
| Corrigendum: Enhanced creative thinking under dopaminergic therapy in Parkinson disease. Annals of neurology. vol 85. issue 3. 2019-11-20. PMID:25914079. |
corrigendum: enhanced creative thinking under dopaminergic therapy in parkinson disease. |
2019-11-20 |
2023-08-13 |
Not clear |
| Oumei Cheng, Xiaoyan Tian, Ying Luo, Shaoshan Mai, Yang Yang, Shengnan Kuang, Qi Chen, Jie Ma, Beibei Chen, Rong Li, Lu Yang, Huan Li, Congli Hu, Jiahua Zhang, Zhihao Chen, Yuke Li, Hui Xia, Ying Xu, Junqing Yan. Liver X receptors agonist promotes differentiation of rat bone marrow derived mesenchymal stem cells into dopaminergic neuron-like cells. Oncotarget. vol 9. issue 1. 2019-11-20. PMID:29416637. |
dopaminergic (da) neurons derived from bone marrow derived mesenchymal stem cells (bmscs) maybe a valuable source for cell replacement therapy in parkinson disease. |
2019-11-20 |
2023-08-13 |
rat |
| Delphine Charvin, Rossella Medori, Robert A Hauser, Olivier Rasco. Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs. Nature reviews. Drug discovery. vol 17. issue 11. 2019-11-20. PMID:30262889. |
therapeutic strategies for parkinson disease: beyond dopaminergic drugs. |
2019-11-20 |
2023-08-13 |
Not clear |
| Delphine Charvin, Rossella Medori, Robert A Hauser, Olivier Rasco. Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs. Nature reviews. Drug discovery. vol 17. issue 11. 2019-11-20. PMID:30262889. |
existing therapeutic strategies for managing parkinson disease (pd), which focus on addressing the loss of dopamine and dopaminergic function linked with degeneration of dopaminergic neurons, are limited by side effects and lack of long-term efficacy. |
2019-11-20 |
2023-08-13 |
Not clear |