| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Felipe Dalvi-Garcia, Luis L Fonseca, Ana Tereza R Vasconcelos, Cecilia Hedin-Pereira, Eberhard O Voi. A model of dopamine and serotonin-kynurenine metabolism in cortisolemia: Implications for depression. PLoS computational biology. vol 17. issue 5. 2021-09-17. PMID:33970902. |
a major factor contributing to the etiology of depression is a neurochemical imbalance of the dopaminergic and serotonergic systems, which is caused by persistently high levels of circulating stress hormones. |
2021-09-17 |
2023-08-13 |
Not clear |
| Ahmed El-Boraie, Rachel F Tyndal. The Role of Pharmacogenetics in Smoking. Clinical pharmacology and therapeutics. vol 110. issue 3. 2021-09-14. PMID:34165800. |
candidate gene studies of smoking phenotypes have identified several pharmacogenes implicated in nicotine's pharmacokinetics (cyp2a6, cyp2b6, cyp2a13, fmos, ugts, and oct2), and nicotine's pharmacodynamic response in the central nervous system (nicotinic acetylcholine receptors, as well as through the dopaminergic and serotonergic systems). |
2021-09-14 |
2023-08-13 |
Not clear |
| Kyoko Hasebe, Michael D Kendig, Margaret J Morri. Mechanisms Underlying the Cognitive and Behavioural Effects of Maternal Obesity. Nutrients. vol 13. issue 1. 2021-09-07. PMID:33467657. |
in animal models, maternal obesogenic diet consumption disrupts cns homeostasis in offspring, which is critical for healthy neurodevelopment, by altering hypothalamic and hippocampal development and recruitment of glial cells, which subsequently dysregulates dopaminergic and serotonergic systems. |
2021-09-07 |
2023-08-13 |
human |
| Gerly Tamm, Kairi Kreegipuu, Jaanus Harr. Platelet MAO activity and COMT Val158Met genotype interaction predicts visual working memory updating efficiency. Behavioural brain research. vol 407. 2021-09-02. PMID:33745984. |
the exact mechanism how serotonergic and dopaminergic systems relate to one another in working memory (wm) updating is unknown. |
2021-09-02 |
2023-08-13 |
human |
| Gerly Tamm, Kairi Kreegipuu, Jaanus Harr. Platelet MAO activity and COMT Val158Met genotype interaction predicts visual working memory updating efficiency. Behavioural brain research. vol 407. 2021-09-02. PMID:33745984. |
platelet monoamine oxidase (mao) has been used as a marker for central serotonergic capacity, and catechol-o-methyltransferase (comt) as a marker for central dopaminergic capacity. |
2021-09-02 |
2023-08-13 |
human |
| Kinga Sałaciak, Natalia Malikowska-Racia, Klaudia Lustyk, Agata Siwek, Monika Głuch-Lutwin, Grzegorz Kazek, Justyna Popiół, Jacek Sapa, Henryk Marona, Dorota Żelaszczyk, Karolina Pytk. Synthesis and Evaluation of the Antidepressant-like Properties of HBK-10, a Novel 2-Methoxyphenylpiperazine Derivative Targeting the 5-HT Pharmaceuticals (Basel, Switzerland). vol 14. issue 8. 2021-08-31. PMID:34451841. |
after assessing the affinity for serotonergic and dopaminergic receptors, and serotonin transporter, we determined intrinsic activity of the compound at the 5-ht |
2021-08-31 |
2023-08-13 |
Not clear |
| Adam Hamed, Miron Bartosz Kurs. Social deprivation substantially changes multi-structural neurotransmitter signature of social interaction: Glutamate concentration in amygdala and VTA as a key factor in social encounter-induced 50-kHz ultrasonic vocalization. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 37. 2021-08-26. PMID:32651127. |
our behavioral and neurochemical analysis indicated that social encounter was a triggering factor of the glutamatergic neurotransmission in the ventral tegmental area (vta), hippocampus, and amygdala; serotonergic neurotransmission in the nacc, cpu, and amygdala; the dopaminergic neurotransmission in the caudate putamen (cpu) and hippocampus; gabaergic neurotransmission in the hippocampus and vta. |
2021-08-26 |
2023-08-13 |
rat |
| I M Vialichko, S V Lelevich, V V Lelevich, E M Doroshenko, V Yu Smirno. [Neurotransmitter changes in the rat brain under combined intoxication induced by alcohol and morphine]. Biomeditsinskaia khimiia. vol 67. issue 4. 2021-08-23. PMID:34414890. |
there are features of changes in the indices of the dopaminergic and serotonergic systems in these experimental conditions, confirmed by the processes of dopamine catabolism and a decrease in the norepinephrine and serotonin concentration in the hypothalamus, which are not observed under individual action of ethanol and morphine. |
2021-08-23 |
2023-08-13 |
rat |
| Kate Z Peters, Joseph F Cheer, Raffaella Tonin. Modulating the Neuromodulators: Dopamine, Serotonin, and the Endocannabinoid System. Trends in neurosciences. vol 44. issue 6. 2021-08-18. PMID:33674134. |
adding an extra layer of complexity to these interactions, the endocannabinoid system is uniquely placed to influence dopaminergic and serotonergic neurotransmission. |
2021-08-18 |
2023-08-13 |
Not clear |
| Neeranjali S Jain, Claire W Ruan, Shanil R Dhanji, Richard J Syme. Psychotropic Drug-Induced Glaucoma: A Practical Guide to Diagnosis and Management. CNS drugs. vol 35. issue 3. 2021-08-09. PMID:33604881. |
selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, monoamine oxidase inhibitors and antipsychotics may trigger angle closure by influencing pupil configuration through adrenergic, anticholinergic, serotonergic or dopaminergic mechanisms. |
2021-08-09 |
2023-08-13 |
Not clear |
| Melissa A Furlong, Kimberly C Paul, Myles Cockburn, Jeff Bronstein, Adrienne Keener, Irish Del Rosario, Aline Duarte Folle, Beate Rit. Ambient Pyrethroid Pesticide Exposures in Adult Life and Depression in Older Residents of California's Central Valley. Environmental epidemiology (Philadelphia, Pa.). vol 4. issue 6. 2021-08-06. PMID:33336137. |
pyrethroid pesticide exposures may be associated with the onset of depression in later life via disruption of dopaminergic, serotonergic, and neurological functioning. |
2021-08-06 |
2023-08-13 |
human |
| Emmanuelle Courtiol, Edenia C Menezes, Catia M Teixeir. Serotonergic regulation of the dopaminergic system: Implications for reward-related functions. Neuroscience and biobehavioral reviews. vol 128. 2021-08-04. PMID:34139249. |
from these studies, it appears that activation of this pathway can lead to reinforcement learning mediated through the excitation of dopaminergic neurons by serotonergic neurons co-transmitting glutamate. |
2021-08-04 |
2023-08-13 |
Not clear |
| b' Matej \\xc4\\xbdupt\\xc3\\xa1k, Danica Michali\\xc4\\x8dkov\\xc3\\xa1, Zden\\xc4\\x9bk Fi\\xc5\\xa1ar, Eva Kitzlerov\\xc3\\xa1, Jana Hroudov\\xc3\\xa. Novel approaches in schizophrenia-from risk factors and hypotheses to novel drug targets. World journal of psychiatry. vol 11. issue 7. 2021-07-31. PMID:34327122.' |
current pharmacotherapy of schizophrenia relies mostly on dopaminergic and serotonergic antagonists/partial agonists, but new findings in the pathophysiology of schizophrenia have allowed the expansion of novel approaches in pharmacotherapy and the establishment of more reliable biomarkers. |
2021-07-31 |
2023-08-13 |
Not clear |
| Jeffery L Cummings, D P Devanand, Stephen M Stah. Dementia-related psychosis and the potential role for pimavanserin. CNS spectrums. 2021-07-30. PMID:32811586. |
despite differences in dementia pathology, the neurobiology underlying psychosis appears to involve dysregulation of a cortical and limbic pathway involving serotonergic, gamma-aminobutyric acid ergic, glutamatergic, and dopaminergic signaling. |
2021-07-30 |
2023-08-13 |
Not clear |
| Cornelia Sindermann, Rayna Sariyska, Jon D Elhai, Christian Monta. Molecular genetics of neurotransmitters and neuropeptides involved in Internet use disorders including first insights on a potential role of hypothalamus' oxytocin hormone. Handbook of clinical neurology. vol 182. 2021-07-28. PMID:34266607. |
finally, studies on differences in molecular genetic predispositions and their associations with differences in iuds will be presented and discussed, including targets related to the dopaminergic and serotonergic system as well as the hypothalamic neuropeptide oxytocin. |
2021-07-28 |
2023-08-13 |
human |
| Mathis Hildonen, Amanda M Levy, Christina Dahl, Victoria A Bjerregaard, Lisbeth Birk Møller, Per Guldberg, Nanette M Debes, Zeynep Tüme. Elevated Expression of Genes. vol 12. issue 1. 2021-07-21. PMID:33445578. |
several neurotransmitter systems have been implicated in disease pathogenesis, and amongst these, the dopaminergic and the serotonergic pathways are the most widely studied. |
2021-07-21 |
2023-08-13 |
Not clear |
| Kelly L L Wong, Aditya Nair, George J Augustin. Changing the Cortical Conductor's Tempo: Neuromodulation of the Claustrum. Frontiers in neural circuits. vol 15. 2021-07-16. PMID:34054437. |
such brain functions arise from brain states that are influenced by neuromodulatory pathways from the cholinergic basal forebrain, dopaminergic substantia nigra and ventral tegmental area, and serotonergic raphe. |
2021-07-16 |
2023-08-13 |
Not clear |
| Juergen Dukart, Stefan Holiga, Michael Rullmann, Rupert Lanzenberger, Peter C T Hawkins, Mitul A Mehta, Swen Hesse, Henryk Barthel, Osama Sabri, Robert Jech, Simon B Eickhof. JuSpace: A tool for spatial correlation analyses of magnetic resonance imaging data with nuclear imaging derived neurotransmitter maps. Human brain mapping. vol 42. issue 3. 2021-07-14. PMID:33079453. |
based on this approach, we introduce a toolbox (juspace) allowing for cross-modal correlation of mri-based measures with nuclear imaging derived estimates covering various neurotransmitter systems including dopaminergic, serotonergic, noradrenergic, and gabaergic (gamma-aminobutric acid) neurotransmission. |
2021-07-14 |
2023-08-13 |
Not clear |
| Juergen Dukart, Stefan Holiga, Michael Rullmann, Rupert Lanzenberger, Peter C T Hawkins, Mitul A Mehta, Swen Hesse, Henryk Barthel, Osama Sabri, Robert Jech, Simon B Eickhof. JuSpace: A tool for spatial correlation analyses of magnetic resonance imaging data with nuclear imaging derived neurotransmitter maps. Human brain mapping. vol 42. issue 3. 2021-07-14. PMID:33079453. |
consistently with the predominant neurodegeneration of dopaminergic and serotonergic system in pd, we find significant spatial associations between rsfmri activity alterations in pd and dopaminergic (d2) and serotonergic systems (5-ht1b). |
2021-07-14 |
2023-08-13 |
Not clear |
| Juergen Dukart, Stefan Holiga, Michael Rullmann, Rupert Lanzenberger, Peter C T Hawkins, Mitul A Mehta, Swen Hesse, Henryk Barthel, Osama Sabri, Robert Jech, Simon B Eickhof. JuSpace: A tool for spatial correlation analyses of magnetic resonance imaging data with nuclear imaging derived neurotransmitter maps. Human brain mapping. vol 42. issue 3. 2021-07-14. PMID:33079453. |
risperidone induced cbf alterations were correlated with its main targets in serotonergic and dopaminergic systems. |
2021-07-14 |
2023-08-13 |
Not clear |