| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caroline Souto, Gabriela Göethel, Caroline Portela Peruzzi, Larissa Vivan Cestonaro, Ingrid Garcia, Daiana Silva Ávila, Vera Eifler-Lima, Helena Carmo, Maria de Lurdes Bastos, Solange C Garcia, Marcelo Dutra Arb. Piperazine designer drugs elicit toxicity in the alternative in vivo model Caenorhabditis elegans. Journal of applied toxicology : JAT. vol 40. issue 3. 2021-07-12. PMID:31755144. |
generally, although less potent than amphetamines, piperazines have dopaminergic and serotonergic activities. |
2021-07-12 |
2023-08-13 |
caenorhabditis_elegans |
| Casper Schmidt, Nikolina Skandali, Carsten Gleesborg, Timo L Kvamme, Hema Schmidt, Kim Frisch, Arne Møller, Valerie Voo. The role of dopaminergic and serotonergic transmission in the processing of primary and monetary reward. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 9. 2021-06-23. PMID:32392573. |
the role of dopaminergic and serotonergic transmission in the processing of primary and monetary reward. |
2021-06-23 |
2023-08-13 |
human |
| Rosana Carvalho Silva, Elisabetta Maffioletti, Massimo Gennarelli, Bernhard T Baune, Alessandra Minell. Biological correlates of early life stressful events in major depressive disorder. Psychoneuroendocrinology. vol 125. 2021-06-22. PMID:33360031. |
evidence indicated that the hypothalamic-pituitary-adrenal (hpa) axis and the serotonergic, dopaminergic, neurotrophin and oxytocin systems might play a role in the mediation between els and mdd. |
2021-06-22 |
2023-08-13 |
human |
| Yu Mao, Yao Xing, Jie Li, Dong Dong, Shoude Zhang, Zhenjiang Zhao, Jingli Xie, Rui Wang, Honglin L. Guanosine ameliorates positive symptoms of schizophrenia American journal of translational research. vol 13. issue 5. 2021-06-22. PMID:34149997. |
there are several hypotheses of pathogenesis in schizophrenia: dopaminergic, glutamatergic, or serotonergic hyperfunction. |
2021-06-22 |
2023-08-13 |
dog |
| Valerie Voon, Juho Joutsa, Joonas Majuri, Kwangyeol Baek, Camilla L Nord, Eveliina Arponen, Sarita Forsback, Valtteri Kaasine. The neurochemical substrates of habitual and goal-directed control. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32127520. |
we assessed the contribution of dopaminergic, serotonergic, and opioidergic systems to this balance across reward and loss domains. |
2021-06-18 |
2023-08-13 |
human |
| Ting Cao, NaNa Li, HuaLin Ca. Candidate metabolic biomarkers for schizophrenia in CNS and periphery: Do any possible associations exist? Schizophrenia research. vol 226. 2021-06-17. PMID:30935700. |
in turn, bdnf also interacts with glutamatergic, dopaminergic and serotonergic systems. |
2021-06-17 |
2023-08-13 |
Not clear |
| Francisco Navarrete, María Salud García-Gutiérrez, Ani Gasparyan, Amaya Austrich-Olivares, Jorge Manzanare. Role of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders. Frontiers in pharmacology. vol 12. 2021-06-08. PMID:34093179. |
furthermore, a special section of the review is focused on the neurobiological mechanisms that might be underlying the 'anti-addictive' action of cbd through the regulation of dopaminergic, opioidergic, serotonergic, and endocannabinoid systems as well as hippocampal neurogenesis. |
2021-06-08 |
2023-08-13 |
Not clear |
| Samuel J Millard, Katrina Weston-Green, Kelly A Newel. The Wistar-Kyoto rat model of endogenous depression: A tool for exploring treatment resistance with an urgent need to focus on sex differences. Progress in neuro-psychopharmacology & biological psychiatry. vol 101. 2021-06-04. PMID:32145362. |
specifically, the wky strain exhibits increased anxiety- and depressive-like behaviours, as well as alterations in hypothalamic pituitary adrenal (hpa) axis, serotonergic, dopaminergic and neurotrophic systems with emerging studies suggesting an involvement of neuroinflammation. |
2021-06-04 |
2023-08-13 |
rat |
| Della Grace Thomas Parambi, Uzma Saleem, Muhammad Ajmal Shah, Fareeha Anwar, Bashir Ahmad, Amna Manzar, Aqsa Itzaz, Seetha Harilal, Md Sahab Uddin, Hoon Kim, Bijo Mathe. Exploring the Therapeutic Potentials of Highly Selective Oxygenated Chalcone Based MAO-B Inhibitors in a Haloperidol-Induced Murine Model of Parkinson's Disease. Neurochemical research. vol 45. issue 11. 2021-06-02. PMID:32939670. |
parkinson's disease (pd) is a neurodegenerative disorder of dopaminergic, noradrenergic, and serotonergic systems, in which dopamine, noradrenaline, and serotonin levels are depleted and lead to the development of motor and non-motor symptoms such as tremor, bradykinesia, weight changes, fatigue, depression, and visual hallucinations. |
2021-06-02 |
2023-08-13 |
Not clear |
| Xue Yang, Jian-You Guo, Qiu-Yu Li, Xiao-Jia Wei, Jia-Yuan Li, Guo-Hui Wan, Jin-Li Sh. [Study on mechanism of Valerianae Jatamansi Rhizoma et Radix against post-traumatic stress disorder based on molecular docking and network pharmacology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 10. 2021-05-31. PMID:34047082. |
totally 29 go terms were obtained by go functional enrichment analysis(p<0.05), and 20 signaling pathways were obtained from kegg pathway enrichment, mainly involving neuroactive ligand-receptor interaction, serotonergic synapse, calcium signaling pathway, camp signaling pathway, dopaminergic synapse, retrograde endocannabinoid signaling, neurotrophin signaling pathway, gap junction, cholinergic synapse, estrogen signaling pathway, glutamatergic synapse and long-term potentiation. |
2021-05-31 |
2023-08-13 |
Not clear |
| Kinga Sałat, Anna Furgała-Woja. Serotonergic Neurotransmission System Modulator, Vortioxetine, and Dopaminergic D Molecules (Basel, Switzerland). vol 26. issue 8. 2021-05-21. PMID:33924258. |
serotonergic neurotransmission system modulator, vortioxetine, and dopaminergic d fibromyalgia is a disease characterized by lowered pain threshold, mood disorders, and decreased muscular strength. |
2021-05-21 |
2023-08-13 |
mouse |
| Kinga Sałat, Anna Furgała-Woja. Serotonergic Neurotransmission System Modulator, Vortioxetine, and Dopaminergic D Molecules (Basel, Switzerland). vol 26. issue 8. 2021-05-21. PMID:33924258. |
impaired serotonergic and dopaminergic neurotransmission are regarded as key factors contributing to fibromyalgia. |
2021-05-21 |
2023-08-13 |
mouse |
| Kinga Sałat, Anna Furgała-Woja. Serotonergic Neurotransmission System Modulator, Vortioxetine, and Dopaminergic D Molecules (Basel, Switzerland). vol 26. issue 8. 2021-05-21. PMID:33924258. |
the present research assessed the effect of serotonergic and dopaminergic system modulators (vortioxetine and ropinirole, respectively) on the pain threshold, depressive-like behavior, anxiety, and motor functions of mice with fibromyalgia-like symptoms induced by subcutaneous reserpine (0.25 mg/kg). |
2021-05-21 |
2023-08-13 |
mouse |
| Leonard Chiu, Ronald Chow, Carlo DeAngelis, Michael Lock, Charles B Simon. Secondary and cumulative meta-analysis of olanzapine for antiemetic prophylaxis for chemotherapy-induced nausea and vomiting: do we still need to study its effectiveness? Annals of palliative medicine. vol 10. issue 3. 2021-05-14. PMID:33440973. |
olanzapine has been found to have antiemetic properties due to its ability to inhibit multiple serotonergic, dopaminergic, alpha-1 adrenergic and histamine receptors. |
2021-05-14 |
2023-08-13 |
Not clear |
| Rosaria Nardello, Fulvio Guccione, Claudia Gliubizzi, Antonio Marino, Mariarita Capizzi, Salvatore Mangan. Resolution of enuresis with aripiprazole in children with psychiatric disorders: two case reports. Journal of medical case reports. vol 15. issue 1. 2021-05-14. PMID:33883037. |
aripiprazole is a third-generation atypical antipsychotic drug that acts as a stabilizer of the dopaminergic and serotonergic system. |
2021-05-14 |
2023-08-13 |
Not clear |
| Delaram Eslimi Esfahani, Mohammad Reza Zarrindas. Cholestasis and behavioral disorders. Gastroenterology and hepatology from bed to bench. vol 14. issue 2. 2021-05-13. PMID:33968336. |
it has been reported that after he, all classical neurotransmitter systems such as opioidergic, dopaminergic, cholinergic, gabaergic, adrenergic, serotonergic, and glutamatergic systems can be altered. |
2021-05-13 |
2023-08-13 |
Not clear |
| Rohini Kuner, Thomas Kune. Cellular Circuits in the Brain and Their Modulation in Acute and Chronic Pain. Physiological reviews. vol 101. issue 1. 2021-05-06. PMID:32525759. |
the review summarizes recent breakthroughs and insights on structure-function properties in nociceptive circuits and higher order sub-neocortical modulatory circuits involved in aversion, learning, reward, and mood and their modulation by endogenous gabaergic inhibition, noradrenergic, cholinergic, dopaminergic, serotonergic, and peptidergic pathways. |
2021-05-06 |
2023-08-13 |
Not clear |
| C van Staden, G de Brouwer, T L Botha, K Finger-Baier, S J Brand, D Wolmaran. Dopaminergic and serotonergic modulation of social reward appraisal in zebrafish (Danio rerio) under circumstances of motivational conflict: Towards a screening test for anti-compulsive drug action. Behavioural brain research. vol 379. 2021-05-03. PMID:31785362. |
dopaminergic and serotonergic modulation of social reward appraisal in zebrafish (danio rerio) under circumstances of motivational conflict: towards a screening test for anti-compulsive drug action. |
2021-05-03 |
2023-08-13 |
zebrafish |
| C van Staden, G de Brouwer, T L Botha, K Finger-Baier, S J Brand, D Wolmaran. Dopaminergic and serotonergic modulation of social reward appraisal in zebrafish (Danio rerio) under circumstances of motivational conflict: Towards a screening test for anti-compulsive drug action. Behavioural brain research. vol 379. 2021-05-03. PMID:31785362. |
towards the development of a zebrafish (danio rerio) screening test for anti-compulsive drug action, we manipulated social reward appraisal under different contexts by means of dopaminergic (apomorphine) and serotonergic (escitalopram) intervention. |
2021-05-03 |
2023-08-13 |
zebrafish |
| C van Staden, G de Brouwer, T L Botha, K Finger-Baier, S J Brand, D Wolmaran. Dopaminergic and serotonergic modulation of social reward appraisal in zebrafish (Danio rerio) under circumstances of motivational conflict: Towards a screening test for anti-compulsive drug action. Behavioural brain research. vol 379. 2021-05-03. PMID:31785362. |
we demonstrate that 1) sight of social conspecifics is an inadequate motivational reinforcer under circumstances of motivational conflict, 2) dopaminergic and serotonergic intervention lessens the importance of an aversive stimulus, increasing the motivational valence of social reward, 3) while serotoninergic intervention maintains reward directed behavior, high-dose dopaminergic intervention bolsters cue-directed responses and 4) high-dose escitalopram reversed apomorphine-induced behavioral inflexibility. |
2021-05-03 |
2023-08-13 |
zebrafish |