| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maya Belghazi, Cécile Iborra, Ophélie Toutendji, Manon Lasserre, Dominique Debanne, Jean-Marc Goaillard, Béatrice Marquèze-Poue. High-Resolution Proteomics Unravel a Native Functional Complex of Cav1.3, SK3, and Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels in Midbrain Dopaminergic Neurons. Cells. vol 13. issue 11. 2024-06-19. PMID:38891076. |
high-resolution proteomics unravel a native functional complex of cav1.3, sk3, and hyperpolarization-activated cyclic nucleotide-gated channels in midbrain dopaminergic neurons. |
2024-06-19 |
2024-06-21 |
Not clear |
| Maya Belghazi, Cécile Iborra, Ophélie Toutendji, Manon Lasserre, Dominique Debanne, Jean-Marc Goaillard, Béatrice Marquèze-Poue. High-Resolution Proteomics Unravel a Native Functional Complex of Cav1.3, SK3, and Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels in Midbrain Dopaminergic Neurons. Cells. vol 13. issue 11. 2024-06-19. PMID:38891076. |
in order to demonstrate the presence of these molecular interactions in situ, we used proximity ligation assay (pla) imaging on midbrain slices containing the substantia nigra, and we could ascertain the presence of these protein complexes specifically in substantia nigra dopaminergic neurons. |
2024-06-19 |
2024-06-21 |
Not clear |
| Shiqiang Zhang, Jingjing Zhang, Yihao Yang, Weidong Zang, Jing Ca. Activation of Pedunculopontine Tegmental Nucleus Alleviates the Pain Induced by the Lesion of Midbrain Dopaminergic Neurons. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38891832. |
activation of pedunculopontine tegmental nucleus alleviates the pain induced by the lesion of midbrain dopaminergic neurons. |
2024-06-19 |
2024-06-21 |
mouse |
| Shiqiang Zhang, Jingjing Zhang, Yihao Yang, Weidong Zang, Jing Ca. Activation of Pedunculopontine Tegmental Nucleus Alleviates the Pain Induced by the Lesion of Midbrain Dopaminergic Neurons. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38891832. |
the loss of midbrain dopaminergic (da) neurons is the fundamental pathological feature of parkinson's disease (pd). |
2024-06-19 |
2024-06-21 |
mouse |
| Hanieh Javid, Rana Rahimian, Misha Salimi, Elaheh Haghani-Samani, Mona Farhadi, Anahita Torkaman-Boutorab. Fumaria vaillantii extract protects PC12 cells against neurotoxicity induced by 6-OHDA. Molecular biology reports. vol 51. issue 1. 2024-06-17. PMID:38884894. |
parkinson's disease is a neurological disorder caused by the loss of dopaminergic neurons in the midbrain. |
2024-06-17 |
2024-06-19 |
Not clear |
| Huiqing Wang, Wenwei Mao, Yuhan Zhang, Wenhui Feng, Bo Bai, Bingyuan Ji, Jing Chen, Baohua Cheng, Fuling Ya. NOX1 triggers ferroptosis and ferritinophagy, contributes to Parkinson's disease. Free radical biology & medicine. 2024-06-14. PMID:38876456. |
the progressive loss of dopaminergic neurons in the midbrain is the hallmark of parkinson's disease (pd). |
2024-06-14 |
2024-06-17 |
Not clear |
| Tuoying Jiang, Jianan Huang, Bo Xu, Zhen Ge, Yi Li, Leiting Wei, Luyang Yu, Jinying L. Human amniotic epithelial stem cell-derived dopaminergic neuron-like cells ameliorate motor dysfunction in a rat model of Parkinson's disease. Life sciences. 2024-06-11. PMID:38862064. |
parkinson's disease (pd) remains a substantial clinical challenge due to the progressive loss of midbrain dopaminergic (da) neurons in nigrostriatal pathway. |
2024-06-11 |
2024-06-14 |
human |
| Pingping Song, Dimitri Krain. Diverse Functions of Parkin in Midbrain Dopaminergic Neurons. Movement disorders : official journal of the Movement Disorder Society. 2024-06-11. PMID:38858837. |
diverse functions of parkin in midbrain dopaminergic neurons. |
2024-06-11 |
2024-06-14 |
human |
| Pingping Song, Dimitri Krain. Diverse Functions of Parkin in Midbrain Dopaminergic Neurons. Movement disorders : official journal of the Movement Disorder Society. 2024-06-11. PMID:38858837. |
parkinson's disease (pd) is characterized by preferential degeneration of midbrain dopaminergic neurons that contributes to its typical clinical manifestation. |
2024-06-11 |
2024-06-14 |
human |
| Pingping Song, Dimitri Krain. Diverse Functions of Parkin in Midbrain Dopaminergic Neurons. Movement disorders : official journal of the Movement Disorder Society. 2024-06-11. PMID:38858837. |
in pd patient neurons, disruption of this pathway on loss of parkin leads to defective recycling of synaptic vesicles and accumulation of toxic oxidized dopamine that at least in part explains preferential vulnerability of midbrain dopaminergic neurons. |
2024-06-11 |
2024-06-14 |
human |
| Gourav Chakraborty, Niladri Patr. Elucidating the Molecular Basis of 14-3-3 Interaction with α-Synuclein: Insights from Molecular Dynamics Simulations and the Design of a Novel Protein-Protein Interaction Inhibitor. The journal of physical chemistry. B. 2024-06-10. PMID:38857533. |
parkinson's disease is a widespread age-related neurodegenerative disorder characterized by the loss of dopaminergic neurons in the midbrain along with the appearance of protein aggregates, termed as "lewy bodies" in the surviving neuronal cells. |
2024-06-10 |
2024-06-14 |
human |
| Cintia Roodveldt, Liliana Bernardino, Ozgur Oztop-Cakmak, Milorad Dragic, Kari Espolin Fladmark, Sibel Ertan, Aktas Busra, Carlos Pita, Lucia Ciglar, Gaetan Garraux, Caroline Williams-Gray, Rodrigo Pacheco, Marina Romero-Ramo. The immune system in Parkinson's disease: what we know so far. Brain : a journal of neurology. 2024-06-04. PMID:38833182. |
parkinson's disease (pd) is characterised neuropathologically by the degeneration of dopaminergic neurons in the ventral midbrain, the accumulation of α-synuclein (α-syn) aggregates in neurons, and chronic neuroinflammation. |
2024-06-04 |
2024-06-06 |
Not clear |
| Tousif Jamal, Xuan Yan, Angelica da Silva Lantyer, Judith G Ter Horst, Tansu Celike. Experience-dependent regulation of dopaminergic signaling in the somatosensory cortex. Progress in neurobiology. 2024-06-04. PMID:38834131. |
these findings suggest that the dopaminergic drive originating from midbrain dopaminergic neurons, targeting the sensory cortex, is subject to experience-dependent regulation and might create a regulatory feed- back loop for modulating sensory processing. |
2024-06-04 |
2024-06-07 |
human |
| Sho K Sugawara, Yukio Nishimur. The Mesocortical System Encodes the Strength of Subsequent Force Generation. Neuroscience insights. vol 19. 2024-06-03. PMID:38827248. |
dopaminergic neurons located in the ventral midbrain (vm) are believed to be the center of incentive motivation. |
2024-06-03 |
2024-06-05 |
human |
| Sho K Sugawara, Yukio Nishimur. The Mesocortical System Encodes the Strength of Subsequent Force Generation. Neuroscience insights. vol 19. 2024-06-03. PMID:38827248. |
although the reaction time has been used as a proxy for incentive motivation mediated by dopaminergic midbrain activity, the premovement activity of the mesocortical pathway is involved in controlling the force strength rather than the initiation of subsequent force generation. |
2024-06-03 |
2024-06-05 |
human |
| Tania Arora, Gaurav Sharma, Vikash Prashar, Randeep Singh, Arti Sharma, Harish Changotra, Jyoti Parkas. Mechanistic Evaluation of miRNAs and Their Targeted Genes in the Pathogenesis and Therapeutics of Parkinson's Disease. Molecular neurobiology. 2024-06-01. PMID:38823001. |
pd is mainly caused by the demolition of the primary dopamine neurotransmitter secretory cells and dopaminergic or dopamine secretory neurons in the substantia nigra pars compacta of the midbrain, which are majorly responsible for motor functions. |
2024-06-01 |
2024-06-03 |
Not clear |
| Samir Kumar Beura, Gaurahari Sahoo, Sonika Yadav, Pooja Yadav, Abhishek Ramachandra Panigrahi, Sunil Kumar Sing. Investigating the role of rotenone on human blood platelets: Molecular insights into abnormal platelet functions in Parkinson's disease. Journal of biochemical and molecular toxicology. vol 38. issue 6. 2024-05-27. PMID:38800879. |
parkinson's disease (pd) is a predominant neuromotor disorder characterized by the selective death of dopaminergic neurons in the midbrain. |
2024-05-27 |
2024-05-31 |
human |
| Suelen L Boschen, Julian Seethaler, Shaohua Wang, Wendy D Lujan, Jodi L Silvernail, Rickey E Carter, Su-Youne Chang, J Luis Luja. Midbrain dopaminergic degeneration differentially modulates primary motor cortex activity and motor behavior in hemi-parkinsonian rats. Research square. 2024-05-27. PMID:38798359. |
midbrain dopaminergic degeneration differentially modulates primary motor cortex activity and motor behavior in hemi-parkinsonian rats. |
2024-05-27 |
2024-05-31 |
rat |
| Francantonio Devoto, Marika Mariano, Edoardo Gornetti, Eraldo Paulesu, Laura Zapparol. Trait food craving predicts functional connectivity between dopaminergic midbrain and the fusiform food area during eating imagery. Frontiers in psychiatry. vol 15. 2024-05-23. PMID:38774434. |
trait food craving predicts functional connectivity between dopaminergic midbrain and the fusiform food area during eating imagery. |
2024-05-23 |
2024-05-27 |
human |
| Francantonio Devoto, Marika Mariano, Edoardo Gornetti, Eraldo Paulesu, Laura Zapparol. Trait food craving predicts functional connectivity between dopaminergic midbrain and the fusiform food area during eating imagery. Frontiers in psychiatry. vol 15. 2024-05-23. PMID:38774434. |
neurofunctional coupling between the dopaminergic midbrain (i.e., ventral tegmental area, vta) and higher-order visual regions may contribute to food craving, leading to the onset or maintenance of obesity. |
2024-05-23 |
2024-05-27 |
human |