| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joseph G Duman, Shalaka Mulherkar, Yen-Kuei Tu, Kelly C Erikson, Christopher P Tzeng, Vasilis C Mavratsas, Tammy Szu-Yu Ho, Kimberley F Tolia. The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest. eLife. vol 8. 2020-02-19. PMID:31461398. |
bai1 loss from mouse or rat hippocampal neurons causes dendritic hypertrophy, whereas bai1 overexpression precipitates dendrite retraction. |
2020-02-19 |
2023-08-13 |
mouse |
| Mourad Belkhelfa, Narimene Beder, Daya Mouhoub, Manel Amri, Rafa Hayet, Nabila Tighilt, Souad Bakheti, Soraya Laimouche, Djamel Azzouz, Rachid Belhadj, Chafia Touil-Boukoff. The involvement of neuroinflammation and necroptosis in the hippocampus during vascular dementia. Journal of neuroimmunology. vol 320. 2019-09-30. PMID:29759140. |
our results showed a β-amyloid deposits, neovascularization, neuronal hypertrophy and neuroinflammation in the hippocampus tissue. |
2019-09-30 |
2023-08-13 |
Not clear |
| M Kodali, B Hattiangady, G A Shetty, A Bates, B Shuai, A K Shett. Curcumin treatment leads to better cognitive and mood function in a model of Gulf War Illness with enhanced neurogenesis, and alleviation of inflammation and mitochondrial dysfunction in the hippocampus. Brain, behavior, and immunity. vol 69. 2019-04-23. PMID:29454881. |
these rats also displayed enhanced neurogenesis and diminished inflammation typified by reduced astrocyte hypertrophy and activated microglia in the hippocampus. |
2019-04-23 |
2023-08-13 |
rat |
| Salwa R Arafa, Candi L LaSarge, Raymund Y K Pun, Shadi Khademi, Steve C Danze. Self-reinforcing effects of mTOR hyperactive neurons on dendritic growth. Experimental neurology. vol 311. 2019-04-10. PMID:30268766. |
loss of the mtor pathway negative regulator pten from hippocampal dentate granule cells leads to neuronal hypertrophy, increased dendritic branching and aberrant basal dendrite formation in animal models. |
2019-04-10 |
2023-08-13 |
mouse |
| Wenbin Li, Kaiming Li, Pujun Guan, Ying Chen, Yuan Xiao, Su Lui, John A Sweeney, Qiyong Gon. Volume alteration of hippocampal subfields in first-episode antipsychotic-naïve schizophrenia patients before and after acute antipsychotic treatment. NeuroImage. Clinical. vol 20. 2019-01-21. PMID:30094166. |
these results indicate subfield-specific hippocampal hypertrophy prior to treatment, and that these abnormalities were reduced after acute antipsychotic therapy in a dose-related manner together with volume reductions in other areas that were not hypertrophic before treatment. |
2019-01-21 |
2023-08-13 |
Not clear |
| F K Odorcyk, F Nicola, L E Duran-Carabali, F Figueiró, J Kolling, A Vizuete, E L Konrath, C A Gonçalves, A T S Wyse, C A Nett. Galantamine administration reduces reactive astrogliosis and upregulates the anti-oxidant enzyme catalase in rats submitted to neonatal hypoxia ischemia. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 62. 2018-05-15. PMID:28760642. |
biochemical analysis was performed in the ipsilesional hippocampus at pnd8 and revealed that pre-hypoxia galantamine treatment: 1) prevented the neuronal loss induced by hi; 2) reduced the hi-induced hypertrophy of astrocytes; and 3) caused an increase in the activity of the anti-oxidant enzyme catalase. |
2018-05-15 |
2023-08-13 |
rat |
| Eva F G Naninck, J Efraim Oosterink, Kit-Yi Yam, Lennart P de Vries, Henk Schierbeek, Johannes B van Goudoever, Rikst-Nynke Verkaik-Schakel, Josèe A Plantinga, Torsten Plosch, Paul J Lucassen, Aniko Koros. Early micronutrient supplementation protects against early stress-induced cognitive impairments. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 31. issue 2. 2017-09-01. PMID:27770020. |
beneficial effects of this early dietary enrichment were associated with prevention of the es-induced rise in corticosterone and adrenal gland hypertrophy did not involve changes in maternal care, hippocampal volume, neurogenesis, or global/nr3c1-specific dna methylation. |
2017-09-01 |
2023-08-13 |
mouse |
| Gabriel Rusanescu, Jianren Ma. Peripheral nerve injury induces adult brain neurogenesis and remodelling. Journal of cellular and molecular medicine. vol 21. issue 2. 2017-07-31. PMID:27665307. |
because neurogenesis-mediated structural plasticity is thought to be restricted to the hippocampus and the subventricular zone, such anatomical rearrangements in other parts of the brain have been thought to result from neuronal plasticity or glial hypertrophy. |
2017-07-31 |
2023-08-13 |
mouse |
| Joo-Hee Park, Ha-Jin Pak, Tae-Ryong Riew, Yoo-Jin Shin, Mun-Yong Le. Increased expression of Slit2 and its receptors Robo1 and Robo4 in reactive astrocytes of the rat hippocampus after transient forebrain ischemia. Brain research. vol 1634. 2016-12-13. PMID:26764532. |
their temporal expression patterns overlapped with the time period in which reactive astrocytes undergo dynamic structural changes and appear hypertrophic in the ischemic hippocampus. |
2016-12-13 |
2023-08-13 |
rat |
| Maheedhar Kodali, Vipan K Parihar, Bharathi Hattiangady, Vikas Mishra, Bing Shuai, Ashok K Shett. Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation. Scientific reports. vol 5. 2016-02-19. PMID:25627672. |
greatly waned neurogenesis, diminished microvasculature, astrocyte hypertrophy and activated microglia are among the most conspicuous structural changes in the aged hippocampus. |
2016-02-19 |
2023-08-13 |
rat |
| Maheedhar Kodali, Vipan K Parihar, Bharathi Hattiangady, Vikas Mishra, Bing Shuai, Ashok K Shett. Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation. Scientific reports. vol 5. 2016-02-19. PMID:25627672. |
resveratrol-treated animals also displayed increased net neurogenesis and microvasculature, and diminished astrocyte hypertrophy and microglial activation in the hippocampus. |
2016-02-19 |
2023-08-13 |
rat |
| M Banerjee, V A Sasse, Y Wang, M Maulik, S Ka. Increased levels and activity of cathepsins B and D in kainate-induced toxicity. Neuroscience. vol 284. 2015-12-22. PMID:25307300. |
our results showed that systemic administration of kainic acid evoked severe loss of neurons along with hypertrophy of astrocytes and microglia in the hippocampus of the adult rat brain. |
2015-12-22 |
2023-08-13 |
human |
| Marloes J A G Henckens, Kajo van der Marel, Annette van der Toorn, Anup G Pillai, Guillén Fernández, Rick M Dijkhuizen, Marian Joël. Stress-induced alterations in large-scale functional networks of the rodent brain. NeuroImage. vol 105. 2015-09-03. PMID:25462693. |
in line with previous research, stressed animals displayed neuronal dendritic hypertrophy in the amygdala and hypotrophy in the hippocampal and medial prefrontal cortex. |
2015-09-03 |
2023-08-13 |
human |
| Miguel Á Pérez, Gonzalo Terreros, Alexies Dagnino-Subiabr. Long-term ω-3 fatty acid supplementation induces anti-stress effects and improves learning in rats. Behavioral and brain functions : BBF. vol 9. 2015-04-15. PMID:23768007. |
chronic stress leads to secretion of the adrenal steroid hormone corticosterone, inducing hippocampal atrophy and dendritic hypertrophy in the rat amygdala. |
2015-04-15 |
2023-08-12 |
rat |
| Ivana Rosenzweig, Matthew J Kempton, William R Crum, Martin Glasser, Milan Milosevic, Sandor Beniczky, Douglas R Corfield, Steven C Williams, Mary J Morrel. Hippocampal hypertrophy and sleep apnea: a role for the ischemic preconditioning? PloS one. vol 8. issue 12. 2015-03-30. PMID:24349453. |
hippocampal hypertrophy and sleep apnea: a role for the ischemic preconditioning? |
2015-03-30 |
2023-08-12 |
Not clear |
| Junfang Wu, Zaorui Zhao, Boris Sabirzhanov, Bogdan A Stoica, Alok Kumar, Tao Luo, Jacob Skovira, Alan I Fade. Spinal cord injury causes brain inflammation associated with cognitive and affective changes: role of cell cycle pathways. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 33. 2014-12-16. PMID:25122899. |
sci caused chronic microglial activation in the hippocampus and cerebral cortex, where microglia with hypertrophic morphologies and m1 phenotype predominated. |
2014-12-16 |
2023-08-13 |
mouse |
| A Amad, A Cachia, P Gorwood, D Pins, C Delmaire, B Rolland, M Mondino, P Thomas, R Jardr. The multimodal connectivity of the hippocampal complex in auditory and visual hallucinations. Molecular psychiatry. vol 19. issue 2. 2014-10-01. PMID:23318999. |
finally, shape analysis showed localized hippocampal hypertrophy in the a+vh group. |
2014-10-01 |
2023-08-12 |
Not clear |
| Israel Camacho-Abrego, Gullermina Tellez-Merlo, Angel I Melo, Antonio Rodríguez-Moreno, Linda Garcés, Fidel De La Cruz, Sergio Zamudio, Gonzalo Flore. Rearrangement of the dendritic morphology of the neurons from prefrontal cortex and hippocampus after subthalamic lesion in Sprague-Dawley rats. Synapse (New York, N.Y.). vol 68. issue 3. 2014-09-23. PMID:24265191. |
we found that stn damage induced a deficit in locomotion measured by open field test with neuronal hypertrophy in pfc (layer 5) and reduced spinogenesis in ca1 ventral hippocampus and pfc (layer 3). |
2014-09-23 |
2023-08-12 |
rat |
| Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Jung Hoon Choi, Woosuk Kim, Hyo Young Jung, Moo-Ho Won, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoo. Effects of treadmill exercise on neural stem cells, cell proliferation, and neuroblast differentiation in the subgranular zone of the dentate gyrus in cyclooxygenase-2 knockout mice. Neurochemical research. vol 38. issue 12. 2014-07-21. PMID:24150751. |
loss of cox-2 expression in the knockout mice was confirmed with two measures: (1) cox immunolabeling in the hippocampus, and (2) the identification of abnormal kidney development using hematoxylin and eosin staining, including subcapsular glomerular hypoplasia and hypertrophy of the deeper cortical glomeruli. |
2014-07-21 |
2023-08-12 |
mouse |
| Vipan K Parihar, Bharathi Hattiangady, Bing Shuai, Ashok K Shett. Mood and memory deficits in a model of Gulf War illness are linked with reduced neurogenesis, partial neuron loss, and mild inflammation in the hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 12. 2014-06-03. PMID:23807240. |
furthermore, these behavioral impairments were associated with reduced hippocampal volume and multiple cellular alterations such as chronic reductions in neural stem cell activity and neurogenesis, partial loss of principal neurons, and mild inflammation comprising sporadic occurrence of activated microglia and significant hypertrophy of astrocytes. |
2014-06-03 |
2023-08-12 |
Not clear |