| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zuzana Sisková, Nik K Sanyal, Adam Orban, Vincent O'Connor, V Hugh Perr. Reactive hypertrophy of synaptic varicosities within the hippocampus of prion-infected mice. Biochemical Society transactions. vol 38. issue 2. 2010-06-11. PMID:20298205. |
reactive hypertrophy of synaptic varicosities within the hippocampus of prion-infected mice. |
2010-06-11 |
2023-08-12 |
mouse |
| Lluís Pujadas, Agnès Gruart, Carles Bosch, Lídia Delgado, Cátia M Teixeira, Daniela Rossi, Luis de Lecea, Albert Martínez, José M Delgado-García, Eduardo Sorian. Reelin regulates postnatal neurogenesis and enhances spine hypertrophy and long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 13. 2010-04-22. PMID:20357114. |
in the hippocampus, the overexpression of reelin resulted in an increase in synaptic contacts and hypertrophy of dendritic spines. |
2010-04-22 |
2023-08-12 |
mouse |
| Rolando Xavier Aviles-Reyes, Maria Florencia Angelo, Alejandro Villarreal, Hugo Rios, Alberto Lazarowski, Alberto Javier Ramo. Intermittent hypoxia during sleep induces reactive gliosis and limited neuronal death in rats: implications for sleep apnea. Journal of neurochemistry. vol 112. issue 4. 2010-03-08. PMID:20002528. |
glial and neuronal alterations were analyzed after 1, 3, 5 and 10 days of exposure to ih (8 h/day during the sleep phase, cycles of 6 min each, 10-21% o2) and observed significant astroglial hyperplasia and hypertrophy in parietal brain cortex and hippocampus by studying gliofibrillary acidic protein, vimentin, s100b and proliferating cell nuclear antigen expression. |
2010-03-08 |
2023-08-12 |
rat |
| Friederike Kienzler, Braxton A Norwood, Robert S Slovite. Hippocampal injury, atrophy, synaptic reorganization, and epileptogenesis after perforant pathway stimulation-induced status epilepticus in the mouse. The Journal of comparative neurology. vol 515. issue 2. 2009-07-15. PMID:19412934. |
mice stimulated for 24 hours developed hippocampal sclerosis, granule cell mossy fiber sprouting, and chronic epilepsy, but not the granule cell layer hypertrophy (granule cell dispersion) produced by intrahippocampal kainate. |
2009-07-15 |
2023-08-12 |
mouse |
| Limei Zhang, Aleph A Corona-Morales, Arturo Vega-González, Joaquín García-Estrada, Alfonso Escoba. Dietary tryptophan restriction in rats triggers astrocyte cytoskeletal hypertrophy in hippocampus and amygdala. Neuroscience letters. vol 450. issue 3. 2009-04-20. PMID:19095041. |
dietary tryptophan restriction in rats triggers astrocyte cytoskeletal hypertrophy in hippocampus and amygdala. |
2009-04-20 |
2023-08-12 |
rat |
| Toshiki Maki, Yasumasa Kokubo, Suguru Nishida, Hideo Suzuki, Shigeki Kuzuhar. An autopsy case with non-herpetic acute limbic encephalitis (NHALE). Neuropathology : official journal of the Japanese Society of Neuropathology. vol 28. issue 5. 2009-03-03. PMID:18282167. |
histologically, there were neuronal loss and severe gliosis with an increase in hypertrophic astrocytes and with perivascular cuffings around several small blood vessels restricted to the hippocampus and the amygdala. |
2009-03-03 |
2023-08-12 |
Not clear |
| Rahşan Göçmen, Kader Karli Oğu. Mega corpus callosum and caudate nuclei with bilateral hippocampal malformation. Diagnostic and interventional radiology (Ankara, Turkey). vol 14. issue 2. 2008-11-10. PMID:18553278. |
we report an unusual case of a thick corpus callosum and hypertrophic caudate nuclei with abnormal bilateral hippocampal development in a 15-year-old female who had mental and motor retardation. |
2008-11-10 |
2023-08-12 |
Not clear |
| Diego Iacono, Richard O'Brien, Susan M Resnick, Alan B Zonderman, Olga Pletnikova, Gay Rudow, Yang An, Mark J West, Barbara Crain, Juan C Troncos. Neuronal hypertrophy in asymptomatic Alzheimer disease. Journal of neuropathology and experimental neurology. vol 67. issue 6. 2008-07-15. PMID:18520776. |
we found significant hypertrophy of the neuronal cell bodies, nuclei, and nucleoli of ca1 of hippocampus and anterior cingulate gyrus neurons in asymad subjects compared with control and mild cognitive impairment cases. |
2008-07-15 |
2023-08-12 |
human |
| Helmut H A Oelschläge. The dolphin brain--a challenge for synthetic neurobiology. Brain research bulletin. vol 75. issue 2-4. 2008-07-10. PMID:18331914. |
additional outstanding features are: (1) the hypertrophy of the neocortex, pons, cerebellum (particularly the paraflocculus), the elliptic nucleus, the facial motor nucleus and the medial accessory inferior olive and (2) the reduction of the hippocampus. |
2008-07-10 |
2023-08-12 |
Not clear |
| Daniel Kondziella, Silje Alvestad, Arne Vaaler, Ursula Sonnewal. Which clinical and experimental data link temporal lobe epilepsy with depression? Journal of neurochemistry. vol 103. issue 6. 2008-01-08. PMID:17887964. |
these may be associated with hippocampal atrophy seen on magnetic resonance imaging and memory impairment as well as altered fear processing and transient hypertrophy of the amygdala. |
2008-01-08 |
2023-08-12 |
Not clear |
| Ulrika Wilhelmsson, Eric A Bushong, Diana L Price, Benjamin L Smarr, Van Phung, Masako Terada, Mark H Ellisman, Milos Pekn. Redefining the concept of reactive astrocytes as cells that remain within their unique domains upon reaction to injury. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 46. 2007-01-05. PMID:17090684. |
despite this hypertrophy of glial fibrillary acidic protein-containing cellular processes, interdigitation between adjacent hippocampal astrocytes remained minimal. |
2007-01-05 |
2023-08-12 |
Not clear |
| S D Kuipers, A Trentani, C Westenbroek, C R Bramham, J Korf, I P Kema, G J Ter Horst, J A Den Boe. Unique patterns of FOS, phospho-CREB and BrdU immunoreactivity in the female rat brain following chronic stress and citalopram treatment. Neuropharmacology. vol 50. issue 4. 2006-07-10. PMID:16309718. |
here we show that chronic footshock stress (21 days) promotes hpa axis hyperactivity (as seen by the increased fos-ir in the paraventricular hypothalamic nucleus (pvn), plasma corticosterone and adrenal hypertrophy), reduces hippocampal brdu immunoreactivity and suppresses cortical-limbic creb phosphorylation in female rats. |
2006-07-10 |
2023-08-12 |
rat |
| S D Kuipers, A Trentani, C Westenbroek, C R Bramham, J Korf, I P Kema, G J Ter Horst, J A Den Boe. Unique patterns of FOS, phospho-CREB and BrdU immunoreactivity in the female rat brain following chronic stress and citalopram treatment. Neuropharmacology. vol 50. issue 4. 2006-07-10. PMID:16309718. |
long-term citalopram treatment, in contrast, attenuates stress-induced elevation of corticosterone levels and adrenal hypertrophy, although it does not reverse footshock-mediated induction of fos-ir in the pvn, inhibition of creb phosphorylation and reduction of hippocampal brdu-labeling. |
2006-07-10 |
2023-08-12 |
rat |
| Christopher M Norris, Inga Kadish, Eric M Blalock, Kuey-Chu Chen, Veronique Thibault, Nada M Porter, Philip W Landfield, Susan D Krane. Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 18. 2006-03-23. PMID:15872113. |
adenoviral transfer of activated calcineurin to primary rat hippocampal cultures resulted in pronounced thickening of astrocyte somata and processes compared with uninfected or virus control cultures, closely mimicking the activated hypertrophic phenotype. |
2006-03-23 |
2023-08-12 |
mouse |
| Maria C Vanzani, Ruben F Iacono, Roberto L Caccuri, Maria I Berri. Immunochemical and morphometric features of astrocyte reactivity vs. plaque location in Alzheimer's disease. Medicina. vol 65. issue 3. 2006-02-23. PMID:16042131. |
concomitant astrocyte hypertrophy, as defined by surface density (sv) values of gfap-immunoreactive material exceeding those of control means, affected a similar proportion of cells in the hippocampus (73%) and the entorhinal cortex (74%) from ad cases. |
2006-02-23 |
2023-08-12 |
Not clear |
| G J Harry, R Sills, M J Schlosser, W E Maie. Neurodegeneration and glia response in rat hippocampus following nitro-L-arginine methyl ester (L-NAME). Neurotoxicity research. vol 3. issue 3. 2005-04-12. PMID:15111256. |
the co-administration of a hippocampal neurotoxicant, trimethyltin (tmt), with the last dose of l-name (2x/day), produced an additive response pattern of neuronal degeneration including both ca1-2 and ca3-4 pyramidal neurons accompanied by tmt-induced astrocyte hypertrophy and prominent microglia reactivity. |
2005-04-12 |
2023-08-12 |
rat |
| Ulrich Gärtner, Alán Alpár, Frank Reimann, Gudrun Seeger, Rolf Heumann, Thomas Arend. Constitutive Ras activity induces hippocampal hypertrophy and remodeling of pyramidal neurons in synRas mice. Journal of neuroscience research. vol 77. issue 5. 2004-12-22. PMID:15352209. |
constitutive ras activity induces hippocampal hypertrophy and remodeling of pyramidal neurons in synras mice. |
2004-12-22 |
2023-08-12 |
mouse |
| Ulrich Gärtner, Alán Alpár, Frank Reimann, Gudrun Seeger, Rolf Heumann, Thomas Arend. Constitutive Ras activity induces hippocampal hypertrophy and remodeling of pyramidal neurons in synRas mice. Journal of neuroscience research. vol 77. issue 5. 2004-12-22. PMID:15352209. |
in synras mice, stereologic investigations revealed hypertrophy of the hippocampus associated with an increase in perikaryal size of pyramidal neurons within the ca2/ca3 region and the gyrus dentatus. |
2004-12-22 |
2023-08-12 |
mouse |
| Paul M Thompson, Kiralee M Hayashi, Sara L Simon, Jennifer A Geaga, Michael S Hong, Yihong Sui, Jessica Y Lee, Arthur W Toga, Walter Ling, Edythe D Londo. Structural abnormalities in the brains of human subjects who use methamphetamine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 26. 2004-12-16. PMID:15229250. |
on average, ma abusers had 7.8% smaller hippocampal volumes than control subjects (p < 0.01; left, p = 0.01; right, p < 0.05) and significant white-matter hypertrophy (7.0%; p < 0.01). |
2004-12-16 |
2023-08-12 |
human |
| Christopher A McPherson, Julie Kubik, Robert N Wine, Christian Lefebvre D'Hellencourt, G Jean Harr. Alterations in cyclin A, B, and D1 in mouse dentate gyrus following TMT-induced hippocampal damage. Neurotoxicity research. vol 5. issue 5. 2004-01-28. PMID:14715453. |
to postnatal day 21 cd-1 male mice produced neuronal necrosis and loss of dentate granule cells, astrocyte hypertrophy, and microglia activation in the hippocampus within 24 hrs. |
2004-01-28 |
2023-08-12 |
mouse |