| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E B Hunziker, R K Schenk, L M Cruz-Oriv. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. The Journal of bone and joint surgery. American volume. vol 69. issue 2. 1987-03-23. PMID:3543020. |
the two most prominent stages are those of cellular proliferation and hypertrophy (including the mineralization of matrix) before the resorption of tissue during vascular invasion. |
1987-03-23 |
2023-08-11 |
rat |
| E B Hunziker, R K Schenk, L M Cruz-Oriv. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. The Journal of bone and joint surgery. American volume. vol 69. issue 2. 1987-03-23. PMID:3543020. |
by applying recently developed stereological procedures and improved methods for the fixation of cartilage, we compared cellular shape modulation, various ultrastructural parameters (surface areas or volumes of endoplasmic reticulum, golgi membranes, and mitochondria), the production of matrix, and cellular turnover for proliferating and hypertrophic chondrocytes within the proximal tibial growth plate of the rat. |
1987-03-23 |
2023-08-11 |
rat |
| E B Hunziker, R K Schenk, L M Cruz-Oriv. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. The Journal of bone and joint surgery. American volume. vol 69. issue 2. 1987-03-23. PMID:3543020. |
by the late hypertrophic stage, fourfold and tenfold increases in the mean cellular height and volume, respectively, and a threefold increase in the mean volume of the matrix per cell were achieved. |
1987-03-23 |
2023-08-11 |
rat |
| S D Boden, F S Kaplan, M D Fallon, R Ruddy, J Belik, E Anday, E Zackai, J Elli. Metatropic dwarfism. Uncoupling of endochondral and perichondral growth. The Journal of bone and joint surgery. American volume. vol 69. issue 2. 1987-03-23. PMID:3805078. |
other observations included prominence of the cartilaginous canals and vascular channels in the reserve zone; clumping of chondrocytes with enhanced staining of the pericellular matrix in the proliferative zone; a decreased ratio of cells to matrix in the hypertrophic zone, with intracellular metachromatic granules and incomplete evolution of chondrocytes; complete absence of an alcian-blue-positive zone of provisional calcification; and, finally, islands of dysplastic chondrocytes in the metaphysis. |
1987-03-23 |
2023-08-11 |
Not clear |
| M E Rosenfeld, T Tsukada, A Chait, E L Bierman, A M Gown, R Ros. Fatty streak expansion and maturation in Watanabe Heritable Hyperlipemic and comparably hypercholesterolemic fat-fed rabbits. Arteriosclerosis (Dallas, Tex.). vol 7. issue 1. 1987-03-17. PMID:3813974. |
in both groups of animals, the fatty streaks expanded due to: 1) the formation of multiple layers of a mixed population of macrophage-derived foam cells and lipid-containing smooth muscle cells, 2) the hypertrophy of the macrophage-derived foam cells, 3) the continued accumulation of extracellular matrix, 4) the insudation of plasma components. |
1987-03-17 |
2023-08-11 |
Not clear |
| K T Weber, J S Janicki, R Pick, C Abrahams, S G Shroff, R I Bashey, R M Che. Collagen in the hypertrophied, pressure-overloaded myocardium. Circulation. vol 75. issue 1 Pt 2. 1987-02-05. PMID:2947751. |
the functional consequences of a remodeling of the collagen matrix that accompanied myocardial hypertrophy remain to be elucidated. |
1987-02-05 |
2023-08-11 |
Not clear |
| L A de Freitas, M Chevallier, D Louis, J A Grimau. Human extrahepatic biliary atresia: portal connective tissue activation related to ductular proliferation. Liver. vol 6. issue 5. 1987-01-20. PMID:3537604. |
the connective matrix pattern observed in periductular areas can be compared to that described in cicatricial and hypertrophic processes where the myofibroblastic cell population is known to play an important role in fibrosis development. |
1987-01-20 |
2023-08-11 |
human |
| N Kawabe, M G Ehrlich, H J Manki. In vivo degradation systems of the epiphyseal cartilage. Clinical orthopaedics and related research. issue 211. 1986-12-01. PMID:3769264. |
accumulated evidence suggests that in the growth cartilage during endochondral ossification, proteoglycans in the extracellular matrix of the lower hypertrophic zone are degraded by proteases and removed before mineralization. |
1986-12-01 |
2023-08-11 |
human |
| B de Bernard, P Bianco, E Bonucci, M Costantini, G C Lunazzi, P Martinuzzi, C Modricky, L Moro, E Panfili, P Pollesell. Biochemical and immunohistochemical evidence that in cartilage an alkaline phosphatase is a Ca2+-binding glycoprotein. The Journal of cell biology. vol 103. issue 4. 1986-11-26. PMID:3771650. |
in the cartilage plate, between the proliferating and the hypertrophic region, a weak immune reactivity is seen in the cytoplasm, whereas in the intercolumnar matrix the collagen fibers appear clearly stained. |
1986-11-26 |
2023-08-11 |
Not clear |
| B de Bernard, P Bianco, E Bonucci, M Costantini, G C Lunazzi, P Martinuzzi, C Modricky, L Moro, E Panfili, P Pollesell. Biochemical and immunohistochemical evidence that in cartilage an alkaline phosphatase is a Ca2+-binding glycoprotein. The Journal of cell biology. vol 103. issue 4. 1986-11-26. PMID:3771650. |
whereas resting cartilage, the intercellular matrix of the resting zone, and calcified matrix do not exhibit any enzyme activity, the zones of maturing and hypertrophic chondrocytes are highly reactive. |
1986-11-26 |
2023-08-11 |
Not clear |
| B Wikström, A Hjerpe, F P Reinholt, B Engfeld. Stereological studies on the epiphyseal growth cartilage and characterization of costal cartilage proteoglycans in the achondroplastic (cn/cn) mouse. Collagen and related research. vol 6. issue 3. 1986-11-25. PMID:3769423. |
the pattern of matrix mineralization seems to be unaffected, even in areas where hypertrophic chondrocytes are completely absent. |
1986-11-25 |
2023-08-11 |
mouse |
| R D Campo, J E Roman. Changes in cartilage proteoglycans associated with calcification. Calcified tissue international. vol 39. issue 3. 1986-11-20. PMID:3093029. |
based on in vivo experiments in which 35 s-sodium sulfate was injected into rabbits, it is shown that proteoglycans from the hypertrophic region becomes part of the calcified cartilage matrix which is to be incorporated into the metaphysis. |
1986-11-20 |
2023-08-11 |
Not clear |
| A Weiss, K von der Mark, M Silberman. A tissue culture system supporting cartilage cell differentiation, extracellular mineralization, and subsequent bone formation, using mouse condylar progenitor cells. Cell differentiation. vol 19. issue 2. 1986-11-12. PMID:3757036. |
by 4 days in culture, many of the cartilage cells showed signs of hypertrophy, while the matrix revealed positive reactivity for type ii collagen and matrix metachromasia. |
1986-11-12 |
2023-08-11 |
mouse |
| M Solursh, K L Jensen, R S Reiter, T M Schmid, T F Linsenmaye. Environmental regulation of type X collagen production by cultures of limb mesenchyme, mesectoderm, and sternal chondrocytes. Developmental biology. vol 117. issue 1. 1986-10-22. PMID:3527817. |
we have examined whether the production of hypertrophic cartilage matrix reflecting a late stage in the development of chondrocytes which participate in endochondral bone formation, is the result of cell lineage, environmental influence, or both. |
1986-10-22 |
2023-08-11 |
chicken |
| G Volpin, J A Rees, S Y Ali, G Bentle. Distribution of alkaline phosphatase activity in experimentally produced callus in rats. The Journal of bone and joint surgery. British volume. vol 68. issue 4. 1986-09-17. PMID:3733843. |
cytoplasmic processes of the hypertrophic chondrocytes appeared to bud and produce matrix vesicles. |
1986-09-17 |
2023-08-11 |
rat |
| G Volpin, J A Rees, S Y Ali, G Bentle. Distribution of alkaline phosphatase activity in experimentally produced callus in rats. The Journal of bone and joint surgery. British volume. vol 68. issue 4. 1986-09-17. PMID:3733843. |
alkaline phosphatase activity was detected along the plasma membrane of the hypertrophic chondrocytes and around the matrix vesicles, before any signs of mineral deposition. |
1986-09-17 |
2023-08-11 |
rat |
| J Klein-Nulend, J P Veldhuijzen, E H Burge. Increased calcification of growth plate cartilage as a result of compressive force in vitro. Arthritis and rheumatism. vol 29. issue 8. 1986-09-17. PMID:3741510. |
we conclude that hypertrophic chondrocytes respond directly to icf and ccf by an increased deposition of calcium-phosphate mineral in the matrix. |
1986-09-17 |
2023-08-11 |
mouse |
| C E Farnum, N J Wilsma. In situ localization of lectin-binding glycoconjugates in the matrix of growth-plate cartilage. The American journal of anatomy. vol 176. issue 1. 1986-08-11. PMID:3728344. |
in the distal hypertrophic zone of growth-plate cartilage, the pericellular matrix surrounding individual chondrocytes and the territorial matrix uniting chondrocytes into columnar groups are invaded by metaphyseal endothelial cells prior to osteogenesis. |
1986-08-11 |
2023-08-11 |
Not clear |
| C E Farnum, N J Wilsma. Ultrastructural histochemical evaluation of growth plate cartilage matrix from healthy and osteochondritic swine. American journal of veterinary research. vol 47. issue 5. 1986-07-07. PMID:3717734. |
in osteochondritic growth plate cartilage from growing swine, the morphology of the pericellular matrix surrounding hypertrophic zone chondrocytes is abnormal and is characteristic of a matrix in which the ordered interactions of matrix macromolecules with each other and with the plasma membrane have been altered. |
1986-07-07 |
2023-08-11 |
Not clear |
| A P Weiss, H D Dorfma. S-100 protein in human cartilage lesions. The Journal of bone and joint surgery. American volume. vol 68. issue 4. 1986-05-20. PMID:3514624. |
the highest intensity of staining was seen in the hypertrophic chondrocytes of the zone of provisional calcification in the growth plate and in the large chondrocytes located adjacent to areas of matrix mineralization in cartilaginous tumors. |
1986-05-20 |
2023-08-11 |
human |