Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
T Ebendal, A Tomac, B J Hoffer, L Olso. Glial cell line-derived neurotrophic factor stimulates fiber formation and survival in cultured neurons from peripheral autonomic ganglia. Journal of neuroscience research. vol 40. issue 2. 1995-06-14. PMID:7745621. |
human recombinant glial cell line-derived neurotrophic factor (gdnf) was tested for its ability to stimulate fiber formation and neuron survival in primary cultures of peripheral ganglia dissected from the chicken embryo. |
1995-06-14 |
2023-08-12 |
human |
J Hudson, A C Granholm, G A Gerhardt, M A Henry, A Hoffman, P Biddle, N S Leela, L Mackerlova, J D Lile, F Collin. Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo. Brain research bulletin. vol 36. issue 5. 1995-05-15. PMID:7712205. |
recently, a novel glial cell line-derived neurotrophic factor (gdnf) has been identified, cloned, and shown to have potent survival- and growth-promoting activity on fetal rat midbrain dopaminergic neurons in cell culture. |
1995-05-15 |
2023-08-12 |
rat |
A D Zurn, E E Baetge, J P Hammang, S A Tan, P Aebische. Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones. Neuroreport. vol 6. issue 1. 1995-05-09. PMID:7703397. |
glial cell line-derived neurotrophic factor (gdnf), a new neurotrophic factor for motoneurones. |
1995-05-09 |
2023-08-12 |
human |
A D Zurn, E E Baetge, J P Hammang, S A Tan, P Aebische. Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones. Neuroreport. vol 6. issue 1. 1995-05-09. PMID:7703397. |
glial cell line-derived neurotrophic factor (gdnf) has been postulated to be a specific dopaminergic neurotrophic factor since it selectively enhances the survival of dopaminergic neurones in vitro. |
1995-05-09 |
2023-08-12 |
human |
C Suter-Crazzolara, K Unsicke. GDNF is expressed in two forms in many tissues outside the CNS. Neuroreport. vol 5. issue 18. 1995-05-04. PMID:7696586. |
a recently cloned neurotrophic factor, glial cell line-derived neurotrophic factor (gdnf), has been implicated in the survival and morphological and functional differentiation of midbrain dopaminergic neurones in vitro. |
1995-05-04 |
2023-08-12 |
rat |
J E Springer, J L Seeburger, J He, A Gabrea, E P Blankenhorn, L W Bergma. cDNA sequence and differential mRNA regulation of two forms of glial cell line-derived neurotrophic factor in Schwann cells and rat skeletal muscle. Experimental neurology. vol 131. issue 1. 1995-04-27. PMID:7895811. |
total rna from rat schwann cells grown in culture and adult rat skeletal muscle was reverse transcribed, amplified for glial cell line-derived neurotrophic factor (gdnf) messenger rna (mrna) using the polymerase chain reaction (pcr), and the pcr products sequenced. |
1995-04-27 |
2023-08-12 |
rat |
B J Hoffer, A Hoffman, K Bowenkamp, P Huettl, J Hudson, D Martin, L F Lin, G A Gerhard. Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. Neuroscience letters. vol 182. issue 1. 1995-04-18. PMID:7891873. |
four weeks later, glial cell line-derived neurotrophic factor (gdnf) or vehicle was injected intranigrally ipsilateral to the lesion (0.1-100 micrograms). |
1995-04-18 |
2023-08-12 |
rat |
K Krieglstein, C Suter-Crazzolara, W H Fischer, K Unsicke. TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity. The EMBO journal. vol 14. issue 4. 1995-04-07. PMID:7882977. |
prominent members of this family include the tgf-beta s 1-5, activins, bone morphogenetic proteins and a recently discovered glial cell line-derived neurotrophic factor (gdnf). |
1995-04-07 |
2023-08-12 |
rat |
D G Schaar, B A Sieber, A C Sherwood, D Dean, G Mendoza, L Ramakrishnan, C F Dreyfus, I B Blac. Multiple astrocyte transcripts encode nigral trophic factors in rat and human. Experimental neurology. vol 130. issue 2. 1995-03-27. PMID:7867768. |
the recent discovery of glial cell line-derived neurotrophic factor (gdnf) identified a novel trophin that selectively increases survival of substantia nigra dopaminergic neurons, which degenerate in parkinson's disease. |
1995-03-27 |
2023-08-12 |
human |
K T Poulsen, M P Armanini, R D Klein, M A Hynes, H S Phillips, A Rosentha. TGF beta 2 and TGF beta 3 are potent survival factors for midbrain dopaminergic neurons. Neuron. vol 13. issue 5. 1994-12-27. PMID:7946360. |
recently, glial cell line-derived neurotrophic factor (gdnf) was shown to be a potent survival factor for these dopaminergic neurons in culture. |
1994-12-27 |
2023-08-12 |
rat |
C E Henderson, H S Phillips, R A Pollock, A M Davies, C Lemeulle, M Armanini, L Simmons, B Moffet, R A Vandlen, L Simpson LC corrected to Simmons, V E Koliatsos, A Rosentha. GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science (New York, N.Y.). vol 266. issue 5187. 1994-12-08. PMID:7973664. |
glial cell line-derived neurotrophic factor (gdnf), originally identified as a trophic factor specific for dopaminergic neurons, was found to be 75-fold more potent than the neurotrophins in supporting the survival of purified embryonic rat motoneurons in culture. |
1994-12-08 |
2023-08-12 |
rat |
C Humpel, B Hoffer, I Strömberg, S Bektesh, F Collins, L Olso. Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger RNA in response to kainate-induced excitation. Neuroscience. vol 59. issue 4. 1994-09-12. PMID:8058121. |
glial cell line-derived neurotrophic factor (gdnf) is a novel member of the transforming growth factor-beta superfamily with potent trophic effects on dopamine neurons. |
1994-09-12 |
2023-08-12 |
rat |
J E Springer, X Mu, L W Bergmann, J Q Trojanowsk. Expression of GDNF mRNA in rat and human nervous tissue. Experimental neurology. vol 127. issue 2. 1994-08-17. PMID:8033959. |
a recently cloned neurotrophic factor, termed glial cell line-derived neurotrophic factor (gdnf), has been reported to exhibit selective neurotrophic properties on ventral mesencephalon dopaminergic neurons, which degenerate in patients with parkinson's disease. |
1994-08-17 |
2023-08-12 |
human |
L F Lin, T J Zhang, F Collins, L G Arme. Purification and initial characterization of rat B49 glial cell line-derived neurotrophic factor. Journal of neurochemistry. vol 63. issue 2. 1994-08-12. PMID:8035200. |
the sequences provide a basis for cloning and expression of the gene for rat and human glial cell line-derived neurotrophic factor (gdnf), confirming that the protein purified as reported here is gdnf. |
1994-08-12 |
2023-08-12 |
human |
I Strömberg, L Björklund, M Johansson, A Tomac, F Collins, L Olson, B Hoffer, C Humpe. Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo. Experimental neurology. vol 124. issue 2. 1994-02-18. PMID:7904571. |
the potential role of glial cell line-derived neurotrophic factor (gdnf) as a trophic molecule for midbrain dopamine neurons was examined using two different approaches: in situ hybridization and intraocular transplantation. |
1994-02-18 |
2023-08-12 |
rat |
D G Schaar, B A Sieber, C F Dreyfus, I B Blac. Regional and cell-specific expression of GDNF in rat brain. Experimental neurology. vol 124. issue 2. 1994-02-18. PMID:8287932. |
the recent isolation of glial cell line-derived growth factor (gdnf), a molecule with apparently selective effects on dopamine (da) neurons in vitro, raises the question of whether this factor is found in normal brain cells. |
1994-02-18 |
2023-08-12 |
rat |
L F Lin, D H Doherty, J D Lile, S Bektesh, F Collin. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science (New York, N.Y.). vol 260. issue 5111. 1993-06-16. PMID:8493557. |
gdnf: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. |
1993-06-16 |
2023-08-12 |
human |
L F Lin, D H Doherty, J D Lile, S Bektesh, F Collin. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science (New York, N.Y.). vol 260. issue 5111. 1993-06-16. PMID:8493557. |
glial cell line-derived neurotrophic factor (gdnf) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily. |
1993-06-16 |
2023-08-12 |
human |