All Relations between serotonergic and 5-ht receptor 2c

Reference Sentence Publish Date Extraction Date Species
Zhenhua Yan, Yufang Chen, Xiadong Zhang, Guanghua L. The metabolites could not be ignored: A comparative study of the metabolite norfluoxetine with its parent fluoxetine on zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands) vol 257 issue 2023 36870174 the functional genes related to serotonergic process (5-ht1aa, 5-ht2c, slc6a4b, and vmat), early growth (egr4), and circadian rhythm (per2) were downregulated by both the norfluoxetine and fluoxetine, indicative of the same mode-of-action of norfluoxetine with its parent in these functions. 2023-03-04 2023-03-06 zebrafish
Deniz Kantar, Alev Duygu Acun, Hakan Er, Ebru Afsar, Piraye Yarg\\xc4\\xb1cogl. Anxiolytic-Like Effects of Extremely Low Frequency Electric Field in Stressed Rats: Involvement of 5-HT2C Receptors. International journal of radiation biology vol issue 2022 35675556 in our study, the effect of low frequency electric fields (lf-ef) on stress-induced electrophysiological, behavioral changes and the possible involvement of serotonergic 5-ht2c receptors were investigated. 2022-06-08 2023-01-27 rat
Fatemeh Sadat Zolfaghari, Fardad Pirri, Evan Gauvin, Maghsoud Peeri, Shayan Amir. Exercise and fluoxetine treatment during adolescence protect against early life stress-induced behavioral abnormalities in adult rats. Pharmacology, biochemistry, and behavior vol 205 issue 2021 33865889 serum cortiscosterone (cort) levels and expression of genes associated with inflammatory factors (il1\xce\xb2, hmgb1, and il6) and serotonergic systems (5-ht2c and 5-ht3a) were studies in the hippocampus (hipp) and prefrontal cortex (pfc). 2021-11-22 2023-01-26 rat
Lonne Heijmans, Martijn R Mons, Elbert A Jooste. A systematic review on descending serotonergic projections and modulation of spinal nociception in chronic neuropathic pain and after spinal cord stimulation. Molecular pain vol 17 issue 2021 34662215 descending serotonergic modulation of nociceptive signaling in spinal dorsal horn in normal adult rat is mainly inhibitory and mediated by 5-ht1a, 5-ht1b, 5-ht2c, 5-ht3 and 5-ht4 receptors. 2021-11-10 2023-01-26 rat
Yasmine A El-Khatib, Rabab H Sayed, Nada A Sallam, Hala F Zaki, Mahmoud M Khatta. 17\\xce\\xb2-Estradiol augments the neuroprotective effect of agomelatine in depressive- and anxiety-like behaviors in ovariectomized rats. Psychopharmacology vol 237 issue 9 2020 32535690 agomelatine (ago) is an agonist of the melatonergic mt1/mt2 receptors and an antagonist of the serotonergic 5-ht2c receptors. 2020-12-30 2023-01-26 rat
Marcel van de Wouw, Roman M Stilling, Veronica L Peterson, Feargal J Ryan, Alan E Hoban, Fergus Shanahan, Gerard Clarke, Marcus J Claesson, Timothy G Dinan, John F Cryan, Harri\\xc3\\xabt Schelleken. Host Microbiota Regulates Central Nervous System Serotonin Receptor 2C Editing in Rodents. ACS chemical neuroscience vol 10 issue 9 2020 31415146 one aspect of the serotonergic system that has been left unexplored in relation to the microbiota is the unique ability of the serotonin receptor 2c (5-ht 2020-08-31 2023-01-26 Not clear
N V Filippova, Yu B Barylnik, A A Shuldyakov, A A Antonov. [Agomelatine in the treatment of major depressive disorder: assessment of the efficacy and tolerability]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova vol 119 issue 5 2019 31317905 agomelatine is an antidepressant agent with an innovative unique pharmacodynamic profile, including melatonergic receptor agonism (mt1 / mt2) and antagonistic effects on serotonergic 5-ht2c receptors. 2019-10-02 2023-01-26 Not clear
M Suhaib Azim, Nidhi B Agarwal, Divya Vohor. Effects of agomelatine on pentylenetetrazole-induced kindling, kindling-associated oxidative stress, and behavioral despair in mice and modulation of its actions by luzindole and 1-(m-chlorophenyl) piperazine. Epilepsy & behavior : E&B vol 72 issue 2018 28578215 in order to explore whether effects are mediated by melatonergic or serotonergic mechanisms, 1-(m-chlorophenyl) piperazine (mcpp), selective 5ht2c receptor agonist and luzindole, melatonergic receptor antagonist, were taken as pharmacological tools. 2018-03-19 2023-01-26 mouse
Ralf Kleene, Harshita Chaudhary, Nicole Karl, Jelena Katic, Agnieszka Kotarska, Kathrin Guitart, Gabriele Loers, Melitta Schachne. Interaction between CHL1 and serotonin receptor 2c regulates signal transduction and behavior in mice. Journal of cell science vol 128 issue 24 2016 26527397 our results demonstrate that chl1 regulates signal transduction pathways through constitutively active 5-ht2c receptor isoforms, thereby altering 5-ht2c receptor functions and implicating chl1 as a new modulator of the serotonergic system. 2016-09-21 2023-01-25 mouse
Rub\\xc3\\xa9n Garc\\xc3\\xada-Cabrerizo, M Julia Garc\\xc3\\xada-Fuste. Chronic MDMA induces neurochemical changes in the hippocampus of adolescent and young adult rats: Down-regulation of apoptotic markers. Neurotoxicology vol 49 issue 2016 26068050 the results showed that chronic mdma caused hippocampal protein deficits in adolescent and young adult rats at different levels: (1) impaired serotonergic (5-ht2a and 5-ht2c post-synaptic receptors) and gabaergic (gad2 enzyme) signaling, and (2) decreased structural cytoskeletal neurofilament proteins (nf-h, nf-m and nf-l). 2016-04-25 2023-01-25 rat
Harri\\xc3\\xabt Schellekens, Pablo N De Francesco, Dalia Kandil, Wessel F Theeuwes, Triona McCarthy, Wesley E P A van Oeffelen, Mario Perell\\xc3\\xb3, Linda Giblin, Timothy G Dinan, John F Crya. Ghrelin's Orexigenic Effect Is Modulated via a Serotonin 2C Receptor Interaction. ACS chemical neuroscience vol 6 issue 7 2016 25727097 the serotonergic system, specifically the 5-ht2c receptor, has been shown to be of critical importance in the regulation of appetite and satiety. 2016-04-19 2023-01-25 rat
J\\xc3\\xb6rg-Peter Voigt, Heidrun Fin. Serotonin controlling feeding and satiety. Behavioural brain research vol 277 issue 2015 25217810 currently, 5-ht1b, 5-ht2c and 5-ht6 receptors have been identified to mediate serotonergic satiety in different ways. 2015-09-08 2023-01-25 Not clear
Canan Kursungoz, Mehmet Ak, Tulin Yani. Effects of risperidone treatment on the expression of hypothalamic neuropeptide in appetite regulation in Wistar rats. Brain research vol 1596 issue 2015 25449893 because pomc neurons express the serotonin receptor (5ht2c), the serotonergic antagonism of risperidone on pomc neurons may cause an increase in appetite and thus increase food consumption even in a short-term trial in rats. 2015-08-24 2023-01-25 rat
Jiamei Lian, Xu-Feng Huang, Nagesh Pai, Chao Den. Chronic betahistine co-treatment reverses olanzapine's effects on dopamine D\\xe2\\x82\\x82 but not 5-HT2A/2C bindings in rat brains. Progress in neuro-psychopharmacology & biological psychiatry vol 56 issue 2015 25149912 this study investigated the effects of chronic treatment of olanzapine and/or betahistine on the binding density of the serotonergic 5-ht2a (5-ht2ar) and 5-ht2c (5-ht2cr) receptors, 5-ht transporter (5-htt), and dopaminergic d\xe2\x82\x82 receptors (d\xe2\x82\x82r) in the brain regions involved in antipsychotic efficacy, including the prefrontal cortex (pfc), cingulate cortex (cg), nucleus accumbens (nac), and caudate putamen (cpu). 2015-07-31 2023-01-25 rat
Mirella Nardo, Plinio C Casarotto, Felipe V Gomes, Francisco S Guimar\\xc3\\xa3e. Cannabidiol reverses the mCPP-induced increase in marble-burying behavior. Fundamental & clinical pharmacology vol 28 issue 5 2015 24118015 meta-chloro-phenyl-piperazine (mcpp) is a nonspecific serotonergic agonist (acting mainly at 5ht1a, 5ht2c and 5ht1d receptors) reported to increase symptoms in ocd patients and block the anticompulsive-like effect of serotonin reuptake inhibitors (sris) in animal models. 2015-05-14 2023-01-25 Not clear
Daniela Baptista-de-Souza, Lorenzo Di Cesare Mannelli, Matteo Zanardelli, Laura Micheli, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souza, Carla Ghelardin. Serotonergic modulation in neuropathy induced by oxaliplatin: effect on the 5HT2C receptor. European journal of pharmacology vol 735 issue 2015 24786153 serotonergic modulation in neuropathy induced by oxaliplatin: effect on the 5ht2c receptor. 2015-01-22 2023-01-25 rat
Daniela Baptista-de-Souza, Lorenzo Di Cesare Mannelli, Matteo Zanardelli, Laura Micheli, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souza, Carla Ghelardin. Serotonergic modulation in neuropathy induced by oxaliplatin: effect on the 5HT2C receptor. European journal of pharmacology vol 735 issue 2015 24786153 besides to increase serotonin levels in the synaptic cleft, fluoxetine is able to block the serotonergic 5-ht2c receptor subtype, which in turn has been involved in the modulation of neuropathic pain. 2015-01-22 2023-01-25 rat
Maximilian Gah. Agomelatine in the treatment of major depressive disorder: an assessment of benefits and risks. Current neuropharmacology vol 12 issue 5 2014 25426008 it is an analogue of melatonin and features a unique pharmacodynamic profile with agonism on both types of melatonergic receptors (mt1/mt2) and antagonism at serotonergic 5-ht2c receptors. 2014-11-26 2023-01-25 Not clear
O Giotako. [Aggressive behavior: theoretical and biological aspects]. Psychiatrike = Psychiatriki vol 24 issue 2 2014 24200542 an imbalance between these receptors with increased serotonergic activity at the 5-ht2a receptor and decreased 5-ht2c receptor sensitivity may increase the possibility of aggression. 2014-09-29 2023-01-25 Not clear
Rudolph M Navar. Olanzapine for the prevention and treatment of chronic nausea and chemotherapy-induced nausea and vomiting. European journal of pharmacology vol 722 issue 2014 24157985 it blocks multiple neurotransmitter receptors including dopaminergic at d1, d2, d3, d4 brain receptors, serotonergic at 5-ht2a, 5-ht2c, 5-ht3, 5-ht6 receptors, catecholamines at alpha1 adrenergic receptors, acetylcholine at muscarinic receptors, and histamine at h1 receptors. 2014-09-28 2023-01-25 Not clear