| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sarah Doss, Alexander U Brandt, Timm Oberwahrenbrock, Matthias Endres, Friedemann Paul, Jan Leo Rinnentha. Metabolic evidence for cerebral neurodegeneration in spinocerebellar ataxia type 1. Cerebellum (London, England). vol 13. issue 2. 2014-09-12. PMID:24085647. |
autosomal-dominant spinocerebellar ataxia type 1 (sca1) is an adult-onset progressive disorder with well-characterized neurodegeneration in the cerebellum and brainstem. |
2014-09-12 |
2023-08-12 |
Not clear |
| Ji Sun Kim, Ji Soo Kim, Jinyoung Youn, Dae-Won Seo, Yuri Jeong, Ji-Hoon Kang, Jeong Ho Park, Jin Whan Ch. Ocular motor characteristics of different subtypes of spinocerebellar ataxia: distinguishing features. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 9. 2014-04-02. PMID:23609488. |
because of frequent involvement of the cerebellum and brainstem, ocular motor abnormalities are key features of spinocerebellar ataxias and may aid in differential diagnosis. |
2014-04-02 |
2023-08-12 |
Not clear |
| S Reimão, C Morgado, L Neto, J Ferreira, M Coelho, M Rosa, J Campo. Diffusion Tensor Imaging in Movement Disorders: Review of Major Patterns and Correlation with Normal Brainstem/cerebellar White Matter. The neuroradiology journal. vol 24. issue 2. 2013-09-25. PMID:24059605. |
the authors reviewed the diffusion tensor imaging (dti) and tractography (dtt) of the normal brainstem and cerebellar white matter in normal volunteers, correlating it with structural magnetic resonance (mr) imaging and dti data obtained in patients evaluated in our institution with movement disorders, including multisystem atrophy (msa), spinocerebellar ataxia (sca), progressive supra-nuclear palsy (psp) and idiopathic parkinson's disease (pd). |
2013-09-25 |
2023-08-12 |
human |
| Domenico Italiano, Patrizia Tarantino, Elvira Valeria De Marco, Rocco Salvatore Calabrò, Placido Bramanti, Aldo Quattrone, Grazia Annes. Spinocerebellar ataxia type 7: report of a new Italian family. Internal medicine (Tokyo, Japan). vol 51. issue 20. 2013-08-05. PMID:23064575. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disorder characterized by degeneration of the cerebellum, brainstem and retina. |
2013-08-05 |
2023-08-12 |
Not clear |
| Antonio Costantini, Maria Immacolata Pala, Marco Colangeli, Serena Savell. Thiamine and spinocerebellar ataxia type 2. BMJ case reports. vol 2013. 2013-06-03. PMID:23314445. |
spinocerebellar ataxia type 2 is a genetic disorder characterised by the degeneration of the cerebellum, its connections and degeneration in brainstem areas. |
2013-06-03 |
2023-08-12 |
Not clear |
| Kathrin Reetz, Ana S Costa, Shahram Mirzazade, Anna Lehmann, Agnes Juzek, Maria Rakowicz, Romana Boguslawska, Ludger Schöls, Christoph Linnemann, Caterina Mariotti, Marina Grisoli, Alexandra Dürr, Bart P van de Warrenburg, Dagmar Timmann, Massimo Pandolfo, Peter Bauer, Heike Jacobi, Till-Karsten Hauser, Thomas Klockgether, Jörg B Schul. Genotype-specific patterns of atrophy progression are more sensitive than clinical decline in SCA1, SCA3 and SCA6. Brain : a journal of neurology. vol 136. issue Pt 3. 2013-04-23. PMID:23423669. |
spinocerebellar ataxias are dominantly inherited disorders that are associated with progressive brain degeneration, mainly affecting the cerebellum and brainstem. |
2013-04-23 |
2023-08-12 |
human |
| Heike Jacobi, Till-Karsten Hauser, Paola Giunti, Christoph Globas, Peter Bauer, Tanja Schmitz-Hübsch, László Baliko, Alessandro Filla, Caterina Mariotti, Maria Rakowicz, Perine Charles, Pascale Ribai, Sandra Szymanski, Jon Infante, Bart P C van de Warrenburg, Alexandra Dürr, Dagmar Timmann, Sylvia Boesch, Roberto Fancellu, Rafal Rola, Chantal Depondt, Ludger Schöls, Elzbieta Zdzienicka, Jun-Suk Kang, Susanne Ratzka, Berry Kremer, Dennis A Stephenson, Béla Melegh, Massimo Pandolfo, Sophie Tezenas du Montcel, Johannes Borkert, Jörg B Schulz, Thomas Klockgethe. Spinocerebellar ataxia types 1, 2, 3 and 6: the clinical spectrum of ataxia and morphometric brainstem and cerebellar findings. Cerebellum (London, England). vol 11. issue 1. 2012-12-04. PMID:21701895. |
spinocerebellar ataxia types 1, 2, 3 and 6: the clinical spectrum of ataxia and morphometric brainstem and cerebellar findings. |
2012-12-04 |
2023-08-12 |
Not clear |
| Caroline Kizilyaprak, Danièle Spehner, Didier Devys, Patrick Schult. The linker histone H1C contributes to the SCA7 nuclear phenotype. Nucleus (Austin, Tex.). vol 2. issue 5. 2012-03-06. PMID:21970987. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disease caused by a polyglutamine expansion in ataxin-7, a subunit of the saga coactivator, which leads to progressive neuronal dysfunction and cell death in cerebellum, brainstem and retina. |
2012-03-06 |
2023-08-12 |
mouse |
| Stephanie A Furrer, Mathini S Mohanachandran, Sarah M Waldherr, Christopher Chang, Vincent A Damian, Bryce L Sopher, Gwenn A Garden, Albert R La Spad. Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 45. 2012-01-04. PMID:22072678. |
spinocerebellar ataxia type 7 (sca7) is a dominantly inherited disorder characterized by cerebellum and brainstem neurodegeneration. |
2012-01-04 |
2023-08-12 |
mouse |
| Federico D'Agata, Paola Caroppo, Andrea Boghi, Mario Coriasco, Marcella Caglio, Bruno Baudino, Katiuscia Sacco, Franco Cauda, Elisabetta Geda, Mauro Bergui, Giuliano Geminiani, Gianni Boris Bradac, Laura Orsi, Paolo Mortar. Linking coordinative and executive dysfunctions to atrophy in spinocerebellar ataxia 2 patients. Brain structure & function. vol 216. issue 3. 2011-12-12. PMID:21461742. |
spinocerebellar ataxias type 2 (sca2) is a rare genetic disorder characterised by the degeneration of the cerebellum, its connections and many brainstem areas. |
2011-12-12 |
2023-08-12 |
Not clear |
| Sarah Stricker, Timm Oberwahrenbrock, Hanna Zimmermann, Jan Schroeter, Matthias Endres, Alexander U Brandt, Friedemann Pau. Temporal retinal nerve fiber loss in patients with spinocerebellar ataxia type 1. PloS one. vol 6. issue 7. 2011-12-06. PMID:21829579. |
autosomal dominant spinocerebellar ataxia type 1 is an adult onset progressive disorder with well characterized neurodegeneration in the cerebellum and brainstem. |
2011-12-06 |
2023-08-12 |
Not clear |
| Alessandra Rufa, Pamela Federigh. Fast versus slow: different saccadic behavior in cerebellar ataxias. Annals of the New York Academy of Sciences. vol 1233. 2011-11-30. PMID:21950987. |
spinocerebellar ataxia type 2 (sca2) is a genetic neurodegenerative disorder primarily characterized by involvement of the brainstem and cerebellum, basal ganglia, spinal cord, cerebral cortex, but white matter is also involved. |
2011-11-30 |
2023-08-12 |
Not clear |
| Gülin Oz, Isabelle Iltis, Diane Hutter, William Thomas, Khalaf O Bushara, Christopher M Gome. Distinct neurochemical profiles of spinocerebellar ataxias 1, 2, 6, and cerebellar multiple system atrophy. Cerebellum (London, England). vol 10. issue 2. 2011-11-10. PMID:20838948. |
we compared cerebellar and brainstem neurochemical profiles measured at 4 t from 26 patients with spinocerebellar ataxias (sca1, n = 9; sca2, n = 7; sca6, n = 5) or cerebellar multiple system atrophy (msa-c, n = 5) and 15 age-matched healthy controls. |
2011-11-10 |
2023-08-12 |
human |
| L Eichler, B Bellenberg, H K Hahn, O Köster, L Schöls, C Luka. Quantitative assessment of brain stem and cerebellar atrophy in spinocerebellar ataxia types 3 and 6: impact on clinical status. AJNR. American journal of neuroradiology. vol 32. issue 5. 2011-09-29. PMID:21372168. |
quantitative assessment of brain stem and cerebellar atrophy in spinocerebellar ataxia types 3 and 6: impact on clinical status. |
2011-09-29 |
2023-08-12 |
Not clear |
| Ya-Chin Chang, Cheng-Yueh Lin, Chen-Ming Hsu, Hsin-Chieh Lin, Yu-Hsiang Chen, Guey-Jen Lee-Chen, Ming-Tsan Su, Long-Sun Ro, Chiung-Mei Chen, Hsiu Mei Hsieh-L. Neuroprotective effects of granulocyte-colony stimulating factor in a novel transgenic mouse model of SCA17. Journal of neurochemistry. vol 118. issue 2. 2011-08-29. PMID:21554323. |
spinocerebellar ataxia type 17 (sca17) is an autosomal dominant inherited disorder characterized by degeneration of spinocerebellar tracts and selected brainstem neurons owing to the expansion of a cag repeat of the human tata-binding protein (htbp) gene. |
2011-08-29 |
2023-08-12 |
mouse |
| Udo Rüb, Joanna C Jen, Heiko Braak, Thomas Delle. Functional neuroanatomy of the human premotor oculomotor brainstem nuclei: insights from postmortem and advanced in vivo imaging studies. Experimental brain research. vol 187. issue 2. 2011-05-25. PMID:18385989. |
data from control brains and from patients suffering from spinocerebellar ataxia type 3, a neurodegenerative disease that severely impairs oculomotor function are discussed and recommendations for the identification of human premotor oculomotor brainstem nuclei in post-mortem studies are given. |
2011-05-25 |
2023-08-12 |
human |
| John H Pula, Christopher M Gomez, Jorge C Katta. Ophthalmologic features of the common spinocerebellar ataxias. Current opinion in ophthalmology. vol 21. issue 6. 2010-11-22. PMID:20811282. |
the spinocerebellar ataxias (scas) are a phenotypically and genetically diverse group of autosomal dominant disorders that cause pathological degeneration in the cerebellum, brainstem, and retina, resulting in a wide variety of ophthalmologic signs and symptoms. |
2010-11-22 |
2023-08-12 |
Not clear |
| Gülin Oz, Diane Hutter, Ivan Tkác, H Brent Clark, Myron D Gross, Hong Jiang, Lynn E Eberly, Khalaf O Bushara, Christopher M Gome. Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 9. 2010-11-04. PMID:20310029. |
here we tested the sensitivity of high field (4 tesla) proton magnetic resonance spectroscopy ((1)h mrs) to neurochemical alterations in the cerebellum and brainstem in spinocerebellar ataxia type 1 (sca1). |
2010-11-04 |
2023-08-12 |
human |
| Scoty M Hearst, Mariper E Lopez, Qingmei Shao, Yong Liu, Parminder J S Vi. Dopamine D2 receptor signaling modulates mutant ataxin-1 S776 phosphorylation and aggregation. Journal of neurochemistry. vol 114. issue 3. 2010-10-06. PMID:20477910. |
spinocerebellar ataxia 1 (sca1) is a dominantly inherited neurodegenerative disease associated with progressive ataxia resulting from the loss of cerebellar purkinje cells (pcs) and neurons in the brainstem. |
2010-10-06 |
2023-08-12 |
mouse |
| Yuan Yuan, Xin Zhou, Feng Ding, Yumin Liu, Jiancheng T. Molecular genetic analysis of a new form of spinocerebellar ataxia in a Chinese Han family. Neuroscience letters. vol 479. issue 3. 2010-09-27. PMID:20641168. |
the pathological changes of spinocerebellar ataxias (scas), mainly include the degeneration of the cerebellum, spinal cord and brainstem. |
2010-09-27 |
2023-08-12 |
Not clear |