| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dien Dang, David Cunningto. Excessive daytime somnolence in spinocerebellar ataxia type 1. Journal of the neurological sciences. vol 290. issue 1-2. 2010-05-13. PMID:20045119. |
autosomal dominant spinocerebellar ataxias (scas) are progressive neurodegenerative disorders which result in dysfunction of the neuronal systems of the spinal cord, brainstem, and cerebellum. |
2010-05-13 |
2023-08-12 |
Not clear |
| Xiaochun Liang, Hong Jiang, Changqing Chen, Gaofeng Zhou, Junling Wang, Shen Zhang, Liwang Lei, Xiaoyi Wang, Beisha Tan. The correlation between magnetic resonance imaging features of the brainstem and cerebellum and clinical features of spinocerebellar ataxia 3/Machado-Joseph disease. Neurology India. vol 57. issue 5. 2010-01-29. PMID:19934555. |
the correlation between magnetic resonance imaging features of the brainstem and cerebellum and clinical features of spinocerebellar ataxia 3/machado-joseph disease. |
2010-01-29 |
2023-08-12 |
Not clear |
| Xiaochun Liang, Hong Jiang, Changqing Chen, Gaofeng Zhou, Junling Wang, Shen Zhang, Liwang Lei, Xiaoyi Wang, Beisha Tan. The correlation between magnetic resonance imaging features of the brainstem and cerebellum and clinical features of spinocerebellar ataxia 3/Machado-Joseph disease. Neurology India. vol 57. issue 5. 2010-01-29. PMID:19934555. |
brainstem and cerebellar atrophy are the most important features in magnetic resonance imaging (mri) in spinocerebellar ataxia type 3/machado-joseph disease (sca3/mjd). |
2010-01-29 |
2023-08-12 |
Not clear |
| F Hoche, K Seidel, E R Brunt, G Auburger, L Schöls, K Bürk, R A de Vos, W den Dunnen, I Bechmann, R Egensperger, C Van Broeckhoven, K Gierga, T Deller, U Rü. Involvement of the auditory brainstem system in spinocerebellar ataxia type 2 (SCA2), type 3 (SCA3) and type 7 (SCA7). Neuropathology and applied neurobiology. vol 34. issue 5. 2009-03-03. PMID:18221259. |
involvement of the auditory brainstem system in spinocerebellar ataxia type 2 (sca2), type 3 (sca3) and type 7 (sca7). |
2009-03-03 |
2023-08-12 |
Not clear |
| Luis Velázquez Pérez, Gilberto Sánchez Cruz, Nalia Canales Ochoa, Roberto Rodríguez Labrada, Julio Rodríguez Díaz, Luis Almaguer Mederos, José Laffita Mes. Electrophysiological features in patients and presymptomatic relatives with spinocerebellar ataxia type 2. Journal of the neurological sciences. vol 263. issue 1-2. 2008-02-14. PMID:17706249. |
motor and sensitive nerve conduction studies, visual (vep), brainstem auditory (baep) and somatosensory (ssep) evoked potentials in 82 patients with spinocerebellar ataxia type 2 (sca2), 62 presymptomatics relatives and 80 controls, correlating it with cag repeat, disease duration and ataxia score were assessed. |
2008-02-14 |
2023-08-12 |
Not clear |
| Jessica E Young, Launce Gouw, Stephanie Propp, Bryce L Sopher, Jillian Taylor, Amy Lin, Evan Hermel, Anna Logvinova, Sylvia F Chen, Shiming Chen, Dale E Bredesen, Ray Truant, Louis J Ptacek, Albert R La Spada, Lisa M Ellerb. Proteolytic cleavage of ataxin-7 by caspase-7 modulates cellular toxicity and transcriptional dysregulation. The Journal of biological chemistry. vol 282. issue 41. 2007-11-27. PMID:17646170. |
spinocerebellar ataxia type 7 (sca7) is a polyglutamine (polyq) disorder characterized by specific degeneration of cerebellar, brainstem, and retinal neurons. |
2007-11-27 |
2023-08-12 |
mouse |
| Carsten Lukas, Ludger Schöls, Barbara Bellenberg, Udo Rüb, Horst Przuntek, Gebhard Schmid, Odo Köster, Boris Sucha. Dissociation of grey and white matter reduction in spinocerebellar ataxia type 3 and 6: a voxel-based morphometry study. Neuroscience letters. vol 408. issue 3. 2007-01-23. PMID:17005321. |
the aim of this study was to examine the different patterns of cerebellar and/or brainstem atrophy in spinocerebellar ataxia (sca) type 3 and 6. |
2007-01-23 |
2023-08-12 |
human |
| Y Hellenbroich, K Gierga, E Reusche, E Schwinger, T Deller, R A I de Vos, C Zühlke, U Rü. Spinocerebellar ataxia type 4 (SCA4): Initial pathoanatomical study reveals widespread cerebellar and brainstem degeneration. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 7. 2007-01-05. PMID:16362839. |
spinocerebellar ataxia type 4 (sca4): initial pathoanatomical study reveals widespread cerebellar and brainstem degeneration. |
2007-01-05 |
2023-08-12 |
Not clear |
| U Rüb, E R Brunt, E Petrasch-Parwez, L Schöls, D Theegarten, G Auburger, K Seidel, C Schultz, K Gierga, H Paulson, C van Broeckhoven, T Deller, R A I de Vo. Degeneration of ingestion-related brainstem nuclei in spinocerebellar ataxia type 2, 3, 6 and 7. Neuropathology and applied neurobiology. vol 32. issue 6. 2006-12-28. PMID:17083478. |
degeneration of ingestion-related brainstem nuclei in spinocerebellar ataxia type 2, 3, 6 and 7. |
2006-12-28 |
2023-08-12 |
Not clear |
| U Rüb, E R Brunt, E Petrasch-Parwez, L Schöls, D Theegarten, G Auburger, K Seidel, C Schultz, K Gierga, H Paulson, C van Broeckhoven, T Deller, R A I de Vo. Degeneration of ingestion-related brainstem nuclei in spinocerebellar ataxia type 2, 3, 6 and 7. Neuropathology and applied neurobiology. vol 32. issue 6. 2006-12-28. PMID:17083478. |
although clinical studies have reported the occurrence of dysphagia in patients with spinocerebellar ataxia type 2 (sca2), type 3 (sca3), type 6 (sca6) and type 7 (sca7), there are neither detailed clinical records concerning the kind of ingestive malfunctions which contribute to dysphagia nor systematic pathoanatomical studies of brainstem regions involved in the ingestive process. |
2006-12-28 |
2023-08-12 |
Not clear |
| U Rüb, E R Brunt, E Petrasch-Parwez, L Schöls, D Theegarten, G Auburger, K Seidel, C Schultz, K Gierga, H Paulson, C van Broeckhoven, T Deller, R A I de Vo. Degeneration of ingestion-related brainstem nuclei in spinocerebellar ataxia type 2, 3, 6 and 7. Neuropathology and applied neurobiology. vol 32. issue 6. 2006-12-28. PMID:17083478. |
in the present study we performed a systematic post mortem study on thick serial tissue sections through the ingestion-related brainstem nuclei of 12 dysphagic patients who suffered from clinically diagnosed and genetically confirmed spinocerebellar ataxias assigned to the cag-repeat or polyglutamine diseases (two sca2, seven sca3, one sca6 and two sca7 patients) and evaluated their medical records. |
2006-12-28 |
2023-08-12 |
Not clear |
| U Rüb, K Gierga, E R Brunt, R A I de Vos, M Bauer, L Schöls, K Bürk, G Auburger, J Bohl, C Schultz, M Vuksic, G J Burbach, H Braak, T Delle. Spinocerebellar ataxias types 2 and 3: degeneration of the pre-cerebellar nuclei isolates the three phylogenetically defined regions of the cerebellum. Journal of neural transmission (Vienna, Austria : 1996). vol 112. issue 11. 2006-07-27. PMID:15785863. |
since no pathoanatomical studies of these nuclei had yet been performed in spinocerebellar ataxia type 2 (sca2) or type 3 (sca3), we carried out a detailed postmortem study of the pre-cerebellar nuclei in six sca2 and seven sca3 patients in order to further characterize the extent of brainstem degeneration in these ataxic disorders. |
2006-07-27 |
2023-08-12 |
Not clear |
| Anna-Lena Ström, Lars Forsgren, Monica Holmber. A role for both wild-type and expanded ataxin-7 in transcriptional regulation. Neurobiology of disease. vol 20. issue 3. 2006-03-09. PMID:15936949. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disease primarily affecting the brainstem, retina and purkinje cells of the cerebellum. |
2006-03-09 |
2023-08-12 |
Not clear |
| Anna-Lena Ström, Lars Forsgren, Monica Holmber. Identification and characterization of Spinocerebellar Ataxia Type 7 (SCA7) isoform SCA7b in mice. Biochimica et biophysica acta. vol 1731. issue 3. 2006-02-03. PMID:16297465. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disease primarily affecting the cerebellum, brainstem and retina. |
2006-02-03 |
2023-08-12 |
mouse |
| Kaisu Nikali, Anu Suomalainen, Juha Saharinen, Mikko Kuokkanen, Johannes N Spelbrink, Tuula Lönnqvist, Leena Peltone. Infantile onset spinocerebellar ataxia is caused by recessive mutations in mitochondrial proteins Twinkle and Twinky. Human molecular genetics. vol 14. issue 20. 2006-01-12. PMID:16135556. |
infantile onset spinocerebellar ataxia (iosca) (mim 271245) is a severe autosomal recessively inherited neurodegenerative disorder characterized by progressive atrophy of the cerebellum, brain stem and spinal cord and sensory axonal neuropathy. |
2006-01-12 |
2023-08-12 |
Not clear |
| L Guerrini, F Lolli, A Ginestroni, G Belli, R Della Nave, C Tessa, S Foresti, M Cosottini, S Piacentini, F Salvi, R Plasmati, D De Grandis, G Siciliano, A Filla, M Mascalch. Brainstem neurodegeneration correlates with clinical dysfunction in SCA1 but not in SCA2. A quantitative volumetric, diffusion and proton spectroscopy MR study. Brain : a journal of neurology. vol 127. issue Pt 8. 2004-10-15. PMID:15240431. |
magnetic resonance (mr) techniques enable in vivo measurement of the atrophy of the brainstem and cerebellum in spinocerebellar ataxia type 1 (sca1) and 2 (sca2) patients, which is accompanied by a decrease in the concentration of n-acetyl aspartate (naa) or of the naa/creatine ratio in the pons and cerebellum. |
2004-10-15 |
2023-08-12 |
human |
| U Rüb, E R Brunt, D Del Turco, R A I de Vos, K Gierga, H Paulson, H Braa. Guidelines for the pathoanatomical examination of the lower brain stem in ingestive and swallowing disorders and its application to a dysphagic spinocerebellar ataxia type 3 patient. Neuropathology and applied neurobiology. vol 29. issue 1. 2003-04-23. PMID:12581335. |
guidelines for the pathoanatomical examination of the lower brain stem in ingestive and swallowing disorders and its application to a dysphagic spinocerebellar ataxia type 3 patient. |
2003-04-23 |
2023-08-12 |
Not clear |
| U Rüb, E R Brunt, D Del Turco, R A I de Vos, K Gierga, H Paulson, H Braa. Guidelines for the pathoanatomical examination of the lower brain stem in ingestive and swallowing disorders and its application to a dysphagic spinocerebellar ataxia type 3 patient. Neuropathology and applied neurobiology. vol 29. issue 1. 2003-04-23. PMID:12581335. |
the application of these guidelines is described by drawing upon the example of the lower brain stem of a male patient with spinocerebellar ataxia type 3, also known as machado-joseph disease, who displayed malfunctions during the preparatory phase of ingestion, as well as lingual and pharyngeal phases of swallowing. |
2003-04-23 |
2023-08-12 |
Not clear |
| J H Anderson, M C Yavuz, B M Kazar, P Christova, C M Gome. The vestibulo-ocular reflex and velocity storage in spinocerebellar ataxia 8. Archives italiennes de biologie. vol 140. issue 4. 2003-01-22. PMID:12228985. |
the autosomal dominant spinocerebellar ataxias (scas) are a group of neurodegenerative diseases characterized by progressive instability of posture and gait, incoordination, ocular motor dysfunction, and dysarthria due to degeneration of cerebellar and brainstem neurons. |
2003-01-22 |
2023-08-12 |
Not clear |
| Ichiro Yabe, Hidenao Sasaki, Seiji Kikuchi, Michio Nonaka, Fumio Moriwaka, Kunio Tashir. Late onset ataxia phenotype in dentatorubro-pallidoluysian atrophy (DRPLA). Journal of neurology. vol 249. issue 4. 2002-12-24. PMID:11967648. |
atrophy of the cerebellum and brain stem an ct or mri had suggested dominant spinocerebellar ataxia as a diagnosis in their ataxia-predominant stage, with a diagnosis of drpla being impossible based on the clinical findings alone. |
2002-12-24 |
2023-08-12 |
Not clear |