| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jenni Jonasson, Anna-Lena Ström, Patricia Hart, Thomas Brännström, Lars Forsgren, Monica Holmber. Expression of ataxin-7 in CNS and non-CNS tissue of normal and SCA7 individuals. Acta neuropathologica. vol 104. issue 1. 2002-09-13. PMID:12070661. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disorder primarily affecting the cerebellum, brain stem and retina. |
2002-09-13 |
2023-08-12 |
Not clear |
| C J Cummings, Y Sun, P Opal, B Antalffy, R Mestril, H T Orr, W H Dillmann, H Y Zoghb. Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Human molecular genetics. vol 10. issue 14. 2001-12-04. PMID:11448943. |
spinocerebellar ataxia type 1 (sca1) is one such disease, characterized by loss of motor coordination due to the degeneration of cerebellar purkinje cells and brain stem neurons. |
2001-12-04 |
2023-08-12 |
mouse |
| M Hsieh, S J Lin, J F Chen, H M Lin, K M Hsiao, S Y Li, C Li, C J Tsa. Identification of the spinocerebellar ataxia type 7 mutation in Taiwan: application of PCR-based Southern blot. Journal of neurology. vol 247. issue 8. 2001-02-01. PMID:11041330. |
spinocerebellar ataxia (sca) type 7 is an autosomal dominant disorder characterized by neural loss, mainly in the cerebellum and regions of the brainstem and particularly the inferior olivary complex. |
2001-02-01 |
2023-08-12 |
Not clear |
| C J Cummings, H T Orr, H Y Zoghb. Progress in pathogenesis studies of spinocerebellar ataxia type 1. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 354. issue 1386. 1999-08-26. PMID:10434309. |
spinocerebellar ataxia type 1 (sca1) is a dominantly inherited disorder characterized by progressive loss of coordination, motor impairment and the degeneration of cerebellar purkinje cells, spinocerebellar tracts and brainstem nuclei. |
1999-08-26 |
2023-08-12 |
mouse |
| J Johansson, L Forsgren, O Sandgren, A Brice, G Holmgren, M Holmber. Expanded CAG repeats in Swedish spinocerebellar ataxia type 7 (SCA7) patients: effect of CAG repeat length on the clinical manifestation. Human molecular genetics. vol 7. issue 2. 1998-03-17. PMID:9425223. |
spinocerebellar ataxia 7 (sca7) is a neurodegenerative disorder characterized by degeneration of the cerebellum, brainstem and retina. |
1998-03-17 |
2023-08-12 |
Not clear |
| M L Hsieh, C Y Yang, H F Tsai, Y Y Chen, C Li, S Y L. The CAG repeats number of spinocerebellar ataxia type 1 gene in normal Taiwanese and in patients with dominant inherited ataxia. Proceedings of the National Science Council, Republic of China. Part B, Life sciences. vol 21. issue 3. 1997-11-21. PMID:9309871. |
spinocerebellar ataxia type 1 (sca 1) is an autosomal dominant disorder characterized by neurodegeneration of the cerebellum, spinal cord and brainstem. |
1997-11-21 |
2023-08-12 |
Not clear |
| S Gilman, A A Sima, L Junck, K J Kluin, R A Koeppe, M E Lohman, R Littl. Spinocerebellar ataxia type 1 with multiple system degeneration and glial cytoplasmic inclusions. Annals of neurology. vol 39. issue 2. 1996-12-12. PMID:8967756. |
spinocerebellar ataxia type 1 (sca1) is a dominantly inherited progressive neurological disorder characterized by neuronal degeneration and reactive gliosis in the cerebellum, brainstem, spinocerebellar tracts, and dorsal columns. |
1996-12-12 |
2023-08-12 |
Not clear |
| I Lopes-Cendes, P Maciel, S Kish, C Gaspar, Y Robitaille, H B Clark, A H Koeppen, M Nance, L Schut, I Silveira, P Coutinho, J Sequeiros, G A Roulea. Somatic mosaicism in the central nervous system in spinocerebellar ataxia type 1 and Machado-Joseph disease. Annals of neurology. vol 40. issue 2. 1996-10-16. PMID:8773601. |
to study the association between neuropathological changes and somatic mosaicism of the cag repeat size in the central nervous system of patients with these two ataxias, we determined the size of the (cag)n expansion in 20 different regions of the brain, brainstem, cerebellum, and spinal cord from 3 patients with spinocerebellar ataxia type 1 and 3 with machado-joseph disease; these regions were selected for their differential neuropathological involvement in the two disorders. |
1996-10-16 |
2023-08-12 |
Not clear |
| E N Burright, H B Clark, A Servadio, T Matilla, R M Feddersen, W S Yunis, L A Duvick, H Y Zoghbi, H T Or. SCA1 transgenic mice: a model for neurodegeneration caused by an expanded CAG trinucleotide repeat. Cell. vol 82. issue 6. 1995-10-27. PMID:7553854. |
spinocerebellar ataxia type 1 (sca1) is an autosomal dominant inherited disorder characterized by degeneration of cerebellar purkinje cells, spinocerebellar tracts, and selective brainstem neurons owing to the expansion of an unstable cag trinucleotide repeat. |
1995-10-27 |
2023-08-12 |
mouse |
| L G Gouw, C D Kaplan, J H Haines, K B Digre, S L Rutledge, A Matilla, M Leppert, H Y Zoghbi, L J Ptáce. Retinal degeneration characterizes a spinocerebellar ataxia mapping to chromosome 3p. Nature genetics. vol 10. issue 1. 1995-09-25. PMID:7647799. |
a heterogeneous group of neurological disorders known as the spinocerebellar ataxias (sca) are characterized by degeneration of the cerebellum, spinal cord and brainstem. |
1995-09-25 |
2023-08-12 |
Not clear |
| H T Orr, M Y Chung, S Banfi, T J Kwiatkowski, A Servadio, A L Beaudet, A E McCall, L A Duvick, L P Ranum, H Y Zoghb. Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1. Nature genetics. vol 4. issue 3. 1993-09-24. PMID:8358429. |
spinocerebellar ataxia type 1 (sca1) is an autosomal dominant disorder characterized by neurodegeneration of the cerebellum, spinal cord and brainstem. |
1993-09-24 |
2023-08-12 |
Not clear |
| W Knezevic, E G Stewart-Wynn. Brainstem auditory evoked responses in hereditary spinocerebellar ataxias. Clinical and experimental neurology. vol 21. 1987-06-23. PMID:3870433. |
brainstem auditory evoked responses in hereditary spinocerebellar ataxias. |
1987-06-23 |
2023-08-11 |
Not clear |
| W Knezevic, E G Stewart-Wynn. Brainstem auditory evoked responses in hereditary spinocerebellar ataxias. Clinical and experimental neurology. vol 21. 1987-06-23. PMID:3870433. |
brainstem auditory evoked responses were recorded in 18 patients with spinocerebellar ataxia, seven with friedreich's ataxia, four with late-onset cerebellar degeneration, and seven with olivopontocerebellar atrophy. |
1987-06-23 |
2023-08-11 |
Not clear |
| W Knezevic, E G Stewart-Wynn. Brainstem auditory evoked responses in hereditary spinocerebellar ataxias. Clinical and experimental neurology. vol 21. 1987-06-23. PMID:3870433. |
the results indicate abnormalities of the brainstem auditory pathways in patients with spinocerebellar ataxias and show that the test is of value in the differential diagnosis of this group of disorders. |
1987-06-23 |
2023-08-11 |
Not clear |