| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Blier, C de Montign. Effect of chronic tricylic antidepressant treatment on the serotoninergic autoreceptor: a microiontophoretic study in the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 314. issue 2. 1981-03-27. PMID:7453831. |
the response of dorsal raphe neurons to intravenous injection of lsd (4 microgram/kg) and to microiontophoretic applications of 5-ht and lsd was assessed 24 h after the last dose. |
1981-03-27 |
2023-08-12 |
rat |
| J M Baraban, G K Aghajania. Suppression of serotonergic neuronal firing by alpha-adrenoceptor antagonists: evidence against GABA mediation. European journal of pharmacology. vol 66. issue 4. 1980-12-16. PMID:6106551. |
recent pharmacological studies have shown that administration of alpha-adrenoceptor antagonists, either systemically or locally in the vicinity of 5-ht cells of the dorsal raphe, suppresses their firing activity. |
1980-12-16 |
2023-08-12 |
Not clear |
| J M Baraban, G K Aghajania. Suppression of serotonergic neuronal firing by alpha-adrenoceptor antagonists: evidence against GABA mediation. European journal of pharmacology. vol 66. issue 4. 1980-12-16. PMID:6106551. |
the finding that systemic administration of picrotoxin, a gaba antagonist, partially reverses the suppression of 5-ht cells produced by systemic application of alpha-adrenoceptor antagonists led to the proposal that gaba interneurons located within the dorsal raphe mediate this suppression of 5-ht cell firing. |
1980-12-16 |
2023-08-12 |
Not clear |
| M Yamamoto, S Murayam. Effect of the serotonergic system on the caudate nucleus. Pharmacology. vol 20. issue 6. 1980-10-21. PMID:6967608. |
effects of l-5-hydroxytryptophan (l-5htp), an active precursor of 5-hydroxytryptamine (5-ht), and electrical stimulation of the dorsal raphe nucleus were observed on the activity of the caudate nucleus in cats with electroencephalographic and evoked potential studies. |
1980-10-21 |
2023-08-12 |
Not clear |
| D M Kuhn, W A Wolf, W Lovenber. Pressor effects of electrical stimulation of the dorsal and median raphe nuclei in anesthetized rats. The Journal of pharmacology and experimental therapeutics. vol 214. issue 2. 1980-09-28. PMID:6104727. |
injections of 2-bromolysergic acid diethylamide (bol), a putative serotonin antagonist, into the anterior hypothalamus/preoptic area significantly attenuates the dorsal raphe pressor effect, whereas treatment of rats with the sympathetic postganglionic blocking agent bretylium prevents the stimulation-induced pressor effect. |
1980-09-28 |
2023-08-12 |
rat |
| J M Baraban, G K Aghajania. Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists. Neuropharmacology. vol 19. issue 4. 1980-08-15. PMID:6104308. |
suppression of firing activity of 5-ht neurons in the dorsal raphe by alpha-adrenoceptor antagonists. |
1980-08-15 |
2023-08-12 |
Not clear |
| P R Solomon, G L Nichols, J M Kiernan, R S Kamer, L J Kapla. Differential effects of lesions in medial and dorsal raphe of the rat: latent inhibition and septohippocampal serotonin levels. Journal of comparative and physiological psychology. vol 94. issue 1. 1980-07-12. PMID:7372849. |
differential effects of lesions in medial and dorsal raphe of the rat: latent inhibition and septohippocampal serotonin levels. |
1980-07-12 |
2023-08-12 |
rat |
| P R Solomon, G L Nichols, J M Kiernan, R S Kamer, L J Kapla. Differential effects of lesions in medial and dorsal raphe of the rat: latent inhibition and septohippocampal serotonin levels. Journal of comparative and physiological psychology. vol 94. issue 1. 1980-07-12. PMID:7372849. |
biochemical analysis indicated that whereas medial raphe lesions significantly reduced serotonin in the septohippocampal complex, dorsal raphe lesions had no such effect. |
1980-07-12 |
2023-08-12 |
rat |
| N M Nicolaou, M Garcia-Munoz, G W Arbuthnott, D Ecclesto. Interactions between serotonergic and dopaminergic systems in rat brain demonstrated by small unilateral lesions of the raphe nuclei. European journal of pharmacology. vol 57. issue 4. 1979-12-27. PMID:573694. |
unilateral lesions in the dorsal raphe (dr) resulted in decreased concentrations of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid and increases in homovanillic acid and 3,4-dihydroxyphenylacetic acid in the ipsilateral substantia nigra (sn). |
1979-12-27 |
2023-08-11 |
rat |
| C C Loullis, D L Felten, P A She. HPLC determination of biogenic amines in discrete brain areas in food deprived rats. Pharmacology, biochemistry, and behavior. vol 11. issue 1. 1979-12-20. PMID:493302. |
norepinephrine (ne), dopamine (da), 5-hydroxytryptophan (5-htp), 5-hydroxytryptamine (5-ht), and 5-hydroxyindole acetic acid (5-hiaa) levels in the lateral hypothalamus (lh), ventromedial hypothalamus (vmh), median raphe (mr) and dorsal raphe (dr) were determined in nondeprived and 48 hr food deprived rats. |
1979-12-20 |
2023-08-11 |
rat |
| J Telner, F Lepore, J P Guillemo. Effects of serotonin content on pain sensitivity in the rat. Pharmacology, biochemistry, and behavior. vol 10. issue 5. 1979-12-18. PMID:158765. |
brain serotonin was elevated via low and high doses of precursor tryptophan and lowered via parachlorophenylalanine or lesions placed in the dorsal raphe nucleus. |
1979-12-18 |
2023-08-11 |
rat |
| P Streit, E Knecht, M Cueno. Transmitter-specific retrograde labeling in the striato-nigral and raphe-nigral pathways. Science (New York, N.Y.). vol 205. issue 4403. 1979-09-01. PMID:451602. |
injecting radioactive transmitters into the rat substantia nigra led to retrograde neuronal labeling either in the dorsal raphe nucleus, after 3h-labeled serotonin injection, or in the caudoputamen, after 3h-labeled gamma-aminobutyric acid injection. |
1979-09-01 |
2023-08-11 |
rat |
| M Sega. Serotonergic innervation of the locus coeruleus from the dorsal raphe and its action on responses to noxious stimuli. The Journal of physiology. vol 286. 1979-07-16. PMID:439032. |
while naloxone did not antagonize the effects of the dorsal raphe stimulation towards locus coeruleus activity, these effects were absent in rats pretreated with a serotonin synthesis inhibitor, pcpa or with 5,7-dht which destroys serotonin-containing terminals, and were reduced by the serotonin antagonist methysergide. |
1979-07-16 |
2023-08-11 |
rat |
| G W Arendash, R V Gall. Serotonin involvement in the inhibition of episodic luteinizing hormone release during electrical stimulation of the midbrain dorsal raphe nucleus in ovariectomized rats. Endocrinology. vol 102. issue 4. 1979-05-23. PMID:154399. |
serotonin involvement in the inhibition of episodic luteinizing hormone release during electrical stimulation of the midbrain dorsal raphe nucleus in ovariectomized rats. |
1979-05-23 |
2023-08-11 |
rat |
| M Héry, E Laplante, C Kordo. Participation of serotonin in the phasic release of luteinizing hormone. II. Effects of lesions of serotonin-containing pathways in the central nervous system. Endocrinology. vol 102. issue 4. 1979-05-23. PMID:744004. |
maximal inhibition of hypothalamic 5-ht and 5-hiaa concentrations were obtained after complete basal mediopontine transections and after lesions of the medial and the dorsal raphe nuclei; under these conditions, the daily variations in plasma lh were reduced by more than 70%. |
1979-05-23 |
2023-08-11 |
rat |
| L D van de Kar, S A Loren. Differential serotonergic innervation of individual hypothalamic nuclei and other forebrain regions by the dorsal and median midbrain raphe nuclei. Brain research. vol 162. issue 1. 1979-04-28. PMID:761086. |
lesions in the midbrain median but not in the dorsal raphe nucleus significantly decreased the serotonin (5-ht) content of the hippocampus (61%), medial preoptic area (49%), suprachiasmatic nucleus (70%) and anterior hypothalamic area (60%). |
1979-04-28 |
2023-08-11 |
Not clear |
| L D van de Kar, S A Loren. Differential serotonergic innervation of individual hypothalamic nuclei and other forebrain regions by the dorsal and median midbrain raphe nuclei. Brain research. vol 162. issue 1. 1979-04-28. PMID:761086. |
electrolytic lesions restricted to either the median or dorsal raphe nucleus produced significant reductions in the 5-ht concentration of the caudate-putamen, anterolateral hypothalamic area (45%) and arcuate nucleus (48--58%). |
1979-04-28 |
2023-08-11 |
Not clear |
| V J Massari, Y Tizabi, D M Jacobowit. Potential noradrenergic regulation of serotonergic neurons in the median raphe nucleus. Experimental brain research. vol 34. issue 1. 1979-03-28. PMID:759225. |
serotonin levels in the median raphe nucleus were significantly reduced by 40%, but levels of serotonin were unaffected in the dorsal raphe nucleus and 8 serotonergic terminal regions. |
1979-03-28 |
2023-08-11 |
rat |
| H J Haigle. Morphine: effects on serotonergic neurons and neurons in areas with a serotonergic input. European journal of pharmacology. vol 51. issue 4. 1979-01-26. PMID:710510. |
microiontophoretic experiments were carried out to determine if morphine affected the firing rate of cells in five areas of the serotonergic system consisting of 5-ht containing neurons in the midbrain raphe nuclei (dorsal raphe and median raphe) or neurons in three areas (amygdala, optic tectum and subiculum) which are thought to receive a 5-ht input from the raphe nuclei. |
1979-01-26 |
2023-08-11 |
Not clear |
| H C Fibiger, F G Lepiane, A G Phillip. Disruption of memory produced by stimulation of the dorsal raphe nucleus: mediation by serotonin. Brain research. vol 155. issue 2. 1978-12-02. PMID:150879. |
disruption of memory produced by stimulation of the dorsal raphe nucleus: mediation by serotonin. |
1978-12-02 |
2023-08-11 |
Not clear |