| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Soubrie, C Blas, A Ferron, J Glowinsk. Chlordiazepoxide reduces in vivo serotonin release in the basal ganglia of encéphale isolé but not anesthetized cats: evidence for a dorsal raphe site of action. The Journal of pharmacology and experimental therapeutics. vol 226. issue 2. 1983-09-20. PMID:6410048. |
chlordiazepoxide reduces in vivo serotonin release in the basal ganglia of encéphale isolé but not anesthetized cats: evidence for a dorsal raphe site of action. |
1983-09-20 |
2023-08-12 |
cat |
| P Soubrie, C Blas, A Ferron, J Glowinsk. Chlordiazepoxide reduces in vivo serotonin release in the basal ganglia of encéphale isolé but not anesthetized cats: evidence for a dorsal raphe site of action. The Journal of pharmacology and experimental therapeutics. vol 226. issue 2. 1983-09-20. PMID:6410048. |
decreased striatal and nigral [3h]serotonin release and enhanced the [3h]amine release in the dorsal raphe. |
1983-09-20 |
2023-08-12 |
cat |
| P Soubrie, C Blas, A Ferron, J Glowinsk. Chlordiazepoxide reduces in vivo serotonin release in the basal ganglia of encéphale isolé but not anesthetized cats: evidence for a dorsal raphe site of action. The Journal of pharmacology and experimental therapeutics. vol 226. issue 2. 1983-09-20. PMID:6410048. |
chlordiazepoxide (10(-5) m) applied to the dorsal raphe reduced nigral [3h]serotonin release while decreasing [3h]serotonin release locally in the dorsal raphe. |
1983-09-20 |
2023-08-12 |
cat |
| R E McClung, J Woo. Ultrastructural differentiation within the central nervous system between indolamines and catecholamines by energy dispersive X-ray analysis following paraformaldehyde pretreatment. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 31. issue 8. 1983-08-26. PMID:6408162. |
dense bodies containing high amounts of chrome were localized in the perikarya of substantia nigra and dorsal raphe neurons following the cytochemical reaction of endogenous dopamine and serotonin (respectively) with glutaraldehyde-dichromate (gdc). |
1983-08-26 |
2023-08-12 |
Not clear |
| F C Zhou, E C Azmiti. Effects of 5,7-dihydroxytryptamine on HRP retrograde transport from hippocampus to midbrain raphe nuclei in the rat. Brain research bulletin. vol 10. issue 4. 1983-08-26. PMID:6860973. |
selective lesioning of 5-ht fibers in the cb or the ff revealed that raphe-cb-hipp neurons and raphe-ff-hipp neurons have a similar distribution pattern in the mrn, but that a dorsal group of neurons at the junction of mrn and dorsal raphe nucleus took the cb route exclusively to innervate the hipp. |
1983-08-26 |
2023-08-12 |
rat |
| P Blier, C de Montign. Effects of quipazine on pre- and postsynaptic serotonin receptors: single cell studies in the rat CNS. Neuropharmacology. vol 22. issue 4. 1983-07-08. PMID:6856049. |
microiontophoretic applications of quipazine on 5-ht-containing neurones in the dorsal raphe and on neurones of two forebrain regions receiving a 5-ht input (the ventral lateral geniculate nucleus and the dorsal hippocampus) consistently depressed neuronal firing rate as did 5-ht and d-lysergic acid diethylamide (lsd). |
1983-07-08 |
2023-08-12 |
rat |
| E Andersen, B Rigor, N Dafn. Electrophysiological evidence of concurrent dorsal raphe input to caudate, septum, habenula, thalamus hippocampus, cerebellum and olfactory bulb. The International journal of neuroscience. vol 18. issue 1-2. 1983-06-10. PMID:6302024. |
the results indicates that the dorsal raphe has a concurrent input to many areas of the brain receiving 5ht afferents and that dr stimulation can modulate the neuronal activity in these regions. |
1983-06-10 |
2023-08-12 |
rat |
| S E Robinso. Effect of specific serotonergic lesions on cholinergic neurons in the hippocampus, cortex and striatum. Life sciences. vol 32. issue 4. 1983-04-15. PMID:6827899. |
local injection of 5,7-dihydroxytryptamine into the dorsal raphe nucleus of desipramine-treated rats decreases the serotonin content of the hippocampus, cortex, and striatum. |
1983-04-15 |
2023-08-12 |
rat |
| M N Perkins, T W Ston. Neuronal responses to 5-hydroxytryptamine and dorsal raphe stimulation within the globus pallidus of the rat. Experimental neurology. vol 79. issue 1. 1983-03-11. PMID:6295798. |
neuronal responses to 5-hydroxytryptamine and dorsal raphe stimulation within the globus pallidus of the rat. |
1983-03-11 |
2023-08-12 |
rat |
| M N Perkins, T W Ston. Neuronal responses to 5-hydroxytryptamine and dorsal raphe stimulation within the globus pallidus of the rat. Experimental neurology. vol 79. issue 1. 1983-03-11. PMID:6295798. |
the projection from the dorsal raphe nucleus (drn) to the globus pallidus (gp) was investigated electrophysiologically, in the urethane-anesthetized rat together with the responsiveness of cells in the gp to 5-hydroxytryptamine (5-ht) and noradrenaline (na). |
1983-03-11 |
2023-08-12 |
rat |
| E H Lee, M A Geye. Selective effects of apomorphine on dorsal raphe neurons: a cytofluorimetric study. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:6184135. |
using a quantitative cytofluorimetric method to detect changes in the intracellular levels of serotonin (5-ht) in individual neurons in rat brain, we have found that the dopaminergic agonist apomorphine increases 5-ht content of dorsal raphe cell bodies without affecting cells in the median raphe nucleus. |
1983-02-25 |
2023-08-12 |
rat |
| E H Lee, M A Geye. Selective effects of apomorphine on dorsal raphe neurons: a cytofluorimetric study. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:6184135. |
liquid chromatographic studies revealed that apomorphine also elevated the concentrations of both 5-ht and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) in striatum, the projection site for dorsal raphe neurons. |
1983-02-25 |
2023-08-12 |
rat |
| E H Lee, M A Geye. Selective effects of apomorphine on dorsal raphe neurons: a cytofluorimetric study. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:6184135. |
conversely, the dopaminergic antagonist haloperidol, at a dose of 0.8 mg/kg, decreased 5-ht levels in dorsal raphe cells. |
1983-02-25 |
2023-08-12 |
rat |
| R B McCal. Neurophysiological effects of hallucinogens on serotonergic neuronal systems. Neuroscience and biobehavioral reviews. vol 6. issue 4. 1983-02-14. PMID:7177511. |
low intravenous doses of the hallucinogen d-lysergic acid diethylamide (lsd) markedly suppress the discharge of serotonin (5-ht)-containing neurons in the dorsal raphe nucleus of the rat. |
1983-02-14 |
2023-08-12 |
rat |
| R B McCal. Neurophysiological effects of hallucinogens on serotonergic neuronal systems. Neuroscience and biobehavioral reviews. vol 6. issue 4. 1983-02-14. PMID:7177511. |
these observations led to the hypothesis that hallucinogens produce their psychoactive effects by acting preferentially upon 5-ht autoreceptors in the dorsal raphe allowing postsynaptic neurons to escape from the tonic inhibitory action of 5-ht neurons. |
1983-02-14 |
2023-08-12 |
rat |
| G V Rebec, S D Curtis, K S Zimmerma. Dorsal raphe neurons: self-inhibition by an amphetamine-induced release of endogenous serotonin. Brain research. vol 251. issue 2. 1983-01-27. PMID:7139334. |
dorsal raphe neurons: self-inhibition by an amphetamine-induced release of endogenous serotonin. |
1983-01-27 |
2023-08-12 |
rat |
| G V Rebec, S D Curtis, K S Zimmerma. Dorsal raphe neurons: self-inhibition by an amphetamine-induced release of endogenous serotonin. Brain research. vol 251. issue 2. 1983-01-27. PMID:7139334. |
the results of these studies indicate that endogenous serotonin, which can be released by a direct infusion of amphetamine, suppresses neuronal activity in the dorsal raphe nucleus by a process of self-inhibition. |
1983-01-27 |
2023-08-12 |
rat |
| M R Park, J A Gonzales-Vegas, S T Kita. Serotonergic excitation from dorsal raphe stimulation recorded intracellularly from rat caudate-putamen. Brain research. vol 243. issue 1. 1982-12-02. PMID:6214298. |
depletion of serotonin by means of prior treatment with para-chlorophenylalanine leads to a reduction in the amplitude of the depolarization which can be evoked by maximal stimulation of dorsal raphe. |
1982-12-02 |
2023-08-12 |
rat |
| C Köhler, V Chan-Palay, H Steinbusc. The distribution and origin of serotonin-containing fibers in the septal area: a combined immunohistochemical and fluorescent retrograde tracing study in the rat. The Journal of comparative neurology. vol 209. issue 1. 1982-12-02. PMID:6749914. |
intraseptal injections of hrp or fluorescent dyes (granular blue, propidium iodide) resulted in retrograde labeling of neuronal cell bodies in several nuclei of the brainstem which are known to contain 5-ht neurons: the dorsal raphe, the median raphe, the nucleus reticularis tegmenti pontis, the raphe pontis, and the raphe magnus. |
1982-12-02 |
2023-08-12 |
rat |
| S L Dickinson, P Slate. Effect of lesioning dopamine, noradrenaline and 5-hydroxytryptamine pathways on tremorine-induced tremor and rigidity. Neuropharmacology. vol 21. issue 8. 1982-12-02. PMID:7121751. |
a median raphe electrolytic lesion affecting 5-hydroxytryptamine (5-ht) neurones had no effect on tremor and rigidity, whereas lesioning the dorsal raphe electrolytically or by injecting 5,6-dihydroxytryptamine prevented rigidity without affecting tremor. |
1982-12-02 |
2023-08-12 |
rat |