| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Yoshimura, H Higash. 5-Hydroxytryptamine mediates inhibitory postsynaptic potentials in rat dorsal raphe neurons. Neuroscience letters. vol 53. issue 1. 1985-06-06. PMID:3991051. |
5-hydroxytryptamine mediates inhibitory postsynaptic potentials in rat dorsal raphe neurons. |
1985-06-06 |
2023-08-11 |
rat |
| S E Robinson, M J Austin, D M Gibben. The role of serotonergic neurons in dorsal raphe, median raphe and anterior hypothalamic pressor mechanisms. Neuropharmacology. vol 24. issue 1. 1985-05-10. PMID:3982602. |
the role of serotonergic neurons in the dorsal raphe and median raphe in the pressor response to electrical stimulation of these areas, and the contribution of these neurons to the pressor response to serotonin (5-ht) in the anterior hypothalamus-preoptic area (ah/po) have been studied by the use of local injections of 5,7-dihydroxytryptamine (5,7-dht), a neurotoxin selective for 5-hydroxytryptamine (5-ht). |
1985-05-10 |
2023-08-11 |
rat |
| S E Robinson, M J Austin, D M Gibben. The role of serotonergic neurons in dorsal raphe, median raphe and anterior hypothalamic pressor mechanisms. Neuropharmacology. vol 24. issue 1. 1985-05-10. PMID:3982602. |
furthermore, the destruction of 5-ht-containing neurons in the dorsal raphe nucleus resulted in an enhanced pressor response to the injection of 5-ht (5 nmol) into the anterior hypothalamus/preoptic area, while the destruction of 5-ht-containing neurons in the median raphe nucleus had no effect on the pressor response to the injection of 5-ht (5 nmol) into the anterior hypothalamus/preoptic area. |
1985-05-10 |
2023-08-11 |
rat |
| S E Robinson, M J Austin, D M Gibben. The role of serotonergic neurons in dorsal raphe, median raphe and anterior hypothalamic pressor mechanisms. Neuropharmacology. vol 24. issue 1. 1985-05-10. PMID:3982602. |
therefore, it appears that 5-ht neurons in the dorsal raphe nucleus are important in the pressor response to electrical stimulation and are involved in a pressor mechanism in the anterior hypothalamus/preoptic area. |
1985-05-10 |
2023-08-11 |
rat |
| G G Yarbrough, D K Singh, D J Pettibon. A comparative electrophysiological and biochemical assessment of serotonin (5-HT) and a novel 5-HT agonist (MK-212) on central serotonergic receptors. Neuropharmacology. vol 23. issue 11. 1985-03-25. PMID:6527736. |
the inhibitory effects of microiontophoretically-applied serotonin (5-ht) and 6-chloro-2[1-piperazinyl]pyrazine (mk-212) were examined on spontaneously firing somatosensory cerebral cortical neurons and dorsal raphe neurons in rats anesthetized with chloral hydrate. |
1985-03-25 |
2023-08-12 |
rat |
| M C McNamara, E E Lawso. Biogenic amine turnover in newborn and adult rabbit brainstem nuclei after pargyline administration. Respiration physiology. vol 58. issue 3. 1985-03-25. PMID:6528107. |
following the administration of the monoamine oxidase inhibitor, pargyline, turnover rates of the biogenic amines norepinephrine (ne), dopamine (da) and serotonin (5ht) were determined in discrete brainstem nuclei: substantia nigra (sn-a9), dorsal raphe (dr), nucleus gigantocellularis (rgi), locus coeruleus (lc-a6), nucleus ambiguus (n amb) and nucleus tractus solitarius (nts) of young and adult rabbits. |
1985-03-25 |
2023-08-12 |
rabbit |
| M J Villar, S R Chiocchio, J H Tramezzan. Origin and termination of dorsal raphe-median eminence projection. Brain research. vol 324. issue 1. 1985-03-18. PMID:6518387. |
the origin and termination of the dorsal raphe (dr)-median eminence (me) projection were studied by combining well-limited small electrolytic lesions of different parts of the dr, the axonal degeneration and the serotonin content in the median eminence. |
1985-03-18 |
2023-08-12 |
Not clear |
| R Romo, P Soubrie, J Glowinsk. Role of thalamic motor nuclei in bilateral regulation of serotoninergic transmission in cat basal ganglia. Brain research. vol 322. issue 2. 1985-02-11. PMID:6095968. |
the release of [3h]5-ht continuously synthesized from [3h]tryptophan was estimated in both caudate nuclei (cn), both substantia nigrae (sn) and in the dorsal raphe nucleus (drn). |
1985-02-11 |
2023-08-12 |
cat |
| N J Duda, K E Moor. Simultaneous determination of 5-hydroxytryptophan and 3,4-dihydroxyphenylalanine in rat brain by HPLC with electrochemical detection following electrical stimulation of the dorsal raphe nucleus. Journal of neurochemistry. vol 44. issue 1. 1985-01-23. PMID:3917287. |
electrical stimulation of 5-hydroxytryptamine neurons in the dorsal raphe nucleus for 30 min at 5 or 10 hz increased 5-hydroxytryptophan accumulation in all brain regions but not in the spinal cord. |
1985-01-23 |
2023-08-11 |
rat |
| P Blier, C de Montigny, D Tardi. Effects of the two antidepressant drugs mianserin and indalpine on the serotonergic system: single-cell studies in the rat. Psychopharmacology. vol 84. issue 2. 1985-01-18. PMID:6438684. |
acute iv administration of mianserin (up to 10 mg/kg) did not decrease the firing rate of dorsal raphe 5-ht neurons. |
1985-01-18 |
2023-08-12 |
rat |
| P Blier, C de Montigny, D Tardi. Effects of the two antidepressant drugs mianserin and indalpine on the serotonergic system: single-cell studies in the rat. Psychopharmacology. vol 84. issue 2. 1985-01-18. PMID:6438684. |
in keeping with its potent reuptake-blocking property, acute iv indalpine produced a marked decrease in the firing rate of dorsal raphe 5-ht neurons (ed50 0.33 mg/kg). |
1985-01-18 |
2023-08-12 |
rat |
| P Blier, C de Montigny, D Tardi. Effects of the two antidepressant drugs mianserin and indalpine on the serotonergic system: single-cell studies in the rat. Psychopharmacology. vol 84. issue 2. 1985-01-18. PMID:6438684. |
the firing rate of dorsal raphe 5-ht neurons was assessed following 2-, 7- and 14-day treatments with indalpine (5 mg/day ip). |
1985-01-18 |
2023-08-12 |
rat |
| M A Geyer, E H Le. Effects of clonidine, piperoxane and locus coeruleus lesion on the serotonergic and dopaminergic systems in raphe and caudate nucleus. Biochemical pharmacology. vol 33. issue 21. 1984-12-05. PMID:6437408. |
using quantitative fluorescence histochemistry and high performance liquid chromatography, we have demonstrated that clonidine, much like apomorphine, preferentially augmented intracellular serotonin (5-ht) fluorescence in the dorsal raphe without affecting 5-ht cells in the median raphe nucleus. |
1984-12-05 |
2023-08-12 |
Not clear |
| M A Geyer, E H Le. Effects of clonidine, piperoxane and locus coeruleus lesion on the serotonergic and dopaminergic systems in raphe and caudate nucleus. Biochemical pharmacology. vol 33. issue 21. 1984-12-05. PMID:6437408. |
6-hydroxydopamine lesions of the locus coeruleus produced a similar increase of 5-ht fluorescence in the dorsal raphe and decrease of ca fluorescence in both the dorsal and median raphe. |
1984-12-05 |
2023-08-12 |
Not clear |
| M A Geyer, E H Le. Effects of clonidine, piperoxane and locus coeruleus lesion on the serotonergic and dopaminergic systems in raphe and caudate nucleus. Biochemical pharmacology. vol 33. issue 21. 1984-12-05. PMID:6437408. |
biochemically, clonidine decreased while piperoxane increased a measure of 5-ht turnover in the corresponding terminal region of the dorsal raphe, the striatum. |
1984-12-05 |
2023-08-12 |
Not clear |
| E H Lee, M A Geye. Dopamine autoreceptor mediation of the effects of apomorphine on serotonin neurons. Pharmacology, biochemistry, and behavior. vol 21. issue 2. 1984-11-15. PMID:6207549. |
the results showed that apo infusion to the dorsal raphe failed to produce a significant effect on serotonin (5-ht) neurons in the dorsal raphe or 5-ht and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) in the corresponding projection site, the striatum. |
1984-11-15 |
2023-08-12 |
rat |
| E H Lee, M A Geye. Dopamine autoreceptor mediation of the effects of apomorphine on serotonin neurons. Pharmacology, biochemistry, and behavior. vol 21. issue 2. 1984-11-15. PMID:6207549. |
conversely, direct apo infusion to the substantia nigra mimicked the effects of systemic apo, namely, elevated 5-ht fluorescence in the dorsal raphe and increased 5-ht and 5-hiaa concentrations in the striatum. |
1984-11-15 |
2023-08-12 |
rat |
| T P Blackburn, J D Kemp, D A Martin, B Co. Evidence that 5-HT agonist-induced rotational behaviour in the rat is mediated via 5-HT1 receptors. Psychopharmacology. vol 83. issue 2. 1984-09-20. PMID:6235531. |
the rotational behaviour induced by 5-ht agonists has been investigated in rats with lesions of the dorsal raphe' nucleus (drn). |
1984-09-20 |
2023-08-12 |
rat |
| G K Aghajanian, J M Lakosk. Hyperpolarization of serotonergic neurons by serotonin and LSD: studies in brain slices showing increased K+ conductance. Brain research. vol 305. issue 1. 1984-09-14. PMID:6331598. |
serotonin and lsd hyperpolarized serotonergic dorsal raphe neurons in rat midbrain slices; the hyperpolarizations were accompanied by a decrease in input resistance, suggesting an increase in potassium conductance as one possible mechanism. |
1984-09-14 |
2023-08-12 |
rat |
| L D Van de Kar, C W Wilkinson, Y Skrobik, M S Brownfield, W F Ganon. Evidence that serotonergic neurons in the dorsal raphe nucleus exert a stimulatory effect on the secretion of renin but not of corticosterone. Brain research. vol 235. issue 2. 1984-08-13. PMID:6765221. |
the data support the hypothesis that serotonergic neurons in the dorsal raphe nucleus are part of a neural pathway mediating increased renin secretion, and that the stimulatory effect of serotonin on corticosterone secretion is mediated by a different pathway. |
1984-08-13 |
2023-08-12 |
rat |