| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joshua M Gulley, Brian R Hoover, Gaynor A Larson, Nancy R Zahnise. Individual differences in cocaine-induced locomotor activity in rats: behavioral characteristics, cocaine pharmacokinetics, and the dopamine transporter. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12902997. |
in rats classified as lcrs or hcrs after 10 mg/kg cocaine injection, we found no differences in (1) novelty-induced locomotion, (2) cocaine levels in dorsal striatum or nucleus accumbens (nac), (3) dat number or affinity in nac, or (4) dat affinity for cocaine in nac. |
2004-02-10 |
2023-08-12 |
rat |
| David Feifel, Paul D Shilling, Ronald Kuczenski, David S Sega. Altered extracellular dopamine concentration in the brains of cholecystokinin-A receptor deficient rats. Neuroscience letters. vol 348. issue 3. 2003-10-06. PMID:12932815. |
in order to further clarify the role of cck-a receptors in the regulation of central da transmission, extracellular da levels in the nucleus accumbens (nac) and the caudate-putamen (cp) of oletf rats, and their non-mutant counterparts, long evans tokushimo otsuka rats, was assessed by microdialysis at baseline and in response to cocaine (15 mg/kg) and amphetamine (0.5 mg/kg) administration. |
2003-10-06 |
2023-08-12 |
rat |
| b' Marzena Karcz-Kubicha, Davide Quarta, Bruce T Hope, Katerina Antoniou, Christa E M\\xc3\\xbcller, Marisela Morales, Charles W Schindler, Steven R Goldberg, Sergi Ferr\\xc3\\xa. Enabling role of adenosine A1 receptors in adenosine A2A receptor-mediated striatal expression of c-fos. The European journal of neuroscience. vol 18. issue 2. 2003-09-24. PMID:12887411.' |
using c-fos immunohistochemistry as an indicator of neural activity, we examined the effects of coactivation of a1rs and a2ars on neural activity and their mechanism of interaction in the caudate-putamen, nucleus accumbens (nac) and prefrontal cortex in rats. |
2003-09-24 |
2023-08-12 |
rat |
| b' Marzena Karcz-Kubicha, Davide Quarta, Bruce T Hope, Katerina Antoniou, Christa E M\\xc3\\xbcller, Marisela Morales, Charles W Schindler, Steven R Goldberg, Sergi Ferr\\xc3\\xa. Enabling role of adenosine A1 receptors in adenosine A2A receptor-mediated striatal expression of c-fos. The European journal of neuroscience. vol 18. issue 2. 2003-09-24. PMID:12887411.' |
coadministration of cgs 21680 and cpa produced a synergistic induction of c-fos expression in the caudate-putamen, cingulate cortex, and especially the nac. |
2003-09-24 |
2023-08-12 |
rat |
| Carrie L Heusner, Thomas S Hnasko, Mark S Szczypka, Yuhong Liu, Matthew J During, Richard D Palmite. Viral restoration of dopamine to the nucleus accumbens is sufficient to induce a locomotor response to amphetamine. Brain research. vol 980. issue 2. 2003-09-16. PMID:12867267. |
this response is specific to the dopamine production in the nac, as restoration of dopamine production to the caudate putamen (cpu) does not fully restore the hyperlocomotive response to amphetamine. |
2003-09-16 |
2023-08-12 |
mouse |
| K D Carr, Y Tsimberg, Y Berman, N Yamamot. Evidence of increased dopamine receptor signaling in food-restricted rats. Neuroscience. vol 119. issue 4. 2003-09-05. PMID:12831870. |
in addition, fos-immunostaining induced by skf-82958 in caudate-putamen (cpu) and nucleus accumbens (nac) was greater in food-restricted than ad libitum-fed rats, as was staining induced by quinpirole in globus pallidus and ventral pallidum. |
2003-09-05 |
2023-08-12 |
rat |
| Erkki Tupala, Håkan Hall, Kim Bergström, Tuija Mantere, Pirkko Räsänen, Terttu Särkioja, Jukka Hiltunen, Jari Tiihone. Different effect of age on dopamine transporters in the dorsal and ventral striatum of controls and alcoholics. Synapse (New York, N.Y.). vol 48. issue 4. 2003-07-25. PMID:12687640. |
the role of the mesolimbic da in brain ethanol reinforcement is well established, with nucleus accumbens (nac) serving as a major terminal area of this system, whereas dorsal striatum is more associated with motor control. |
2003-07-25 |
2023-08-12 |
human |
| Erkki Tupala, Håkan Hall, Kim Bergström, Tuija Mantere, Pirkko Räsänen, Terttu Särkioja, Jukka Hiltunen, Jari Tiihone. Different effect of age on dopamine transporters in the dorsal and ventral striatum of controls and alcoholics. Synapse (New York, N.Y.). vol 48. issue 4. 2003-07-25. PMID:12687640. |
the mean densities of dat declined significantly with age in controls and type 2 alcoholics in dorsal striatum (nc, pu) (range of correlation coefficient from -0.49 to -0.94), but not statistically significantly in nac. |
2003-07-25 |
2023-08-12 |
human |
| Erkki Tupala, Håkan Hall, Kim Bergström, Tuija Mantere, Pirkko Räsänen, Terttu Särkioja, Jukka Hiltunen, Jari Tiihone. Different effect of age on dopamine transporters in the dorsal and ventral striatum of controls and alcoholics. Synapse (New York, N.Y.). vol 48. issue 4. 2003-07-25. PMID:12687640. |
this is supported by the notion that dat in nac and dorsal striatum have different molecular weights. |
2003-07-25 |
2023-08-12 |
human |
| Stefan D Schlussman, Yong Zhang, Vadim Yuferov, K Steven LaForge, Ann Ho, Mary Jeanne Kree. Acute 'binge' cocaine administration elevates dynorphin mRNA in the caudate putamen of C57BL/6J but not 129/J mice. Brain research. vol 974. issue 1-2. 2003-07-22. PMID:12742644. |
preprodynorphin mrna was measured in the nucleus accumbens (nac) and caudate putamen (cpu) after 3-day 'binge' pattern cocaine administration in c57bl/6j and 129/j mice, strains which differ in behavior and in dopamine increases in the cpu after 'binge' cocaine. |
2003-07-22 |
2023-08-12 |
mouse |
| Thomas M Loonam, Pierre A H Noailles, Jing Yu, Judy P Q Zhu, Jesus A Angul. Substance P and cholecystokinin regulate neurochemical responses to cocaine and methamphetamine in the striatum. Life sciences. vol 73. issue 6. 2003-07-17. PMID:12801594. |
the mechanism of action of drugs of abuse like cocaine and amphetamines has been studied extensively in the dopamine terminal field areas of the caudate-putamen (cpu) and the nucleus accumbens (nac) of the rodent brain. |
2003-07-17 |
2023-08-12 |
mouse |
| Roberto I Melendez, Zachary A Rodd-Henricks, William J McBride, James M Murph. Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12637946. |
rats were bilaterally implanted with microdialysis probes aimed at the vp and gp or nucleus accumbens (nac) and dorsal striatum (dstr). |
2003-06-11 |
2023-08-12 |
rat |
| Jong Y Bahk, Shupeng Li, Moon S Park, Myeong O Ki. Dopamine D1 and D2 receptor mRNA up-regulation in the caudate-putamen and nucleus accumbens of rat brains by smoking. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 6. 2003-03-26. PMID:12452531. |
the neurotransmitter dopamine (da) is important in the reward and reinforcing properties of many addictive drugs: however, the effect of nicotine by cigarette smoking itself on the expression of da receptors in the caudate-putamen (cpu), nucleus accumbens (nac) and olfactory tubercle (otu) has not been elucidated completely. |
2003-03-26 |
2023-08-12 |
rat |
| Joshua M Gulley, Suzanne Doolen, Nancy R Zahnise. Brief, repeated exposure to substrates down-regulates dopamine transporter function in Xenopus oocytes in vitro and rat dorsal striatum in vivo. Journal of neurochemistry. vol 83. issue 2. 2002-11-20. PMID:12423250. |
high-speed chronoamperometry was used to measure clearance of exogenously applied da in dorsal striatum (str) and nucleus accumbens (nac) of anesthetized rats. |
2002-11-20 |
2023-08-12 |
human |
| Jilla Sabeti, Greg A Gerhardt, Nancy R Zahnise. Acute cocaine differentially alters accumbens and striatal dopamine clearance in low and high cocaine locomotor responders: behavioral and electrochemical recordings in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 302. issue 3. 2002-09-18. PMID:12183681. |
the role of the dopamine transporter (dat) in mediating the behavioral differences in cocaine responsiveness in lcrs and hcrs was investigated by high-speed chronoamperometric recording of exogenous dopamine (da) clearance signals in nucleus accumbens (nac) and dorsal striatum (dstr). |
2002-09-18 |
2023-08-12 |
rat |
| Z I Storozheva, I I Afanas'ev, A T Proshin, V S Kudri. [Dynamics of the level of extracellular dopamine in the rat brain during formation of conditioned fear and acoustic startle habituation]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 52. issue 2. 2002-06-24. PMID:12013655. |
the content of extracellular dopamine (da) was estimated in dorsal striatum (ds), nucleus accumbens (nac), and prefrontal cortex (pfc) of rat brain during two sessions of acoustic startle habituation consisting of 10 trials each with 24-hour intersession and 20-s intertrial intervals. |
2002-06-24 |
2023-08-12 |
rat |
| J-Y Chang, L Chen, F Luo, L-H Shi, D J Woodwar. Neuronal responses in the frontal cortico-basal ganglia system during delayed matching-to-sample task: ensemble recording in freely moving rats. Experimental brain research. vol 142. issue 1. 2002-02-27. PMID:11797085. |
one hundred seventy-one neurons in the medial prefrontal cortex (mpfc), 51 in the dorsal striatum (str), and 93 in the nucleus accumbens (nac) were recorded during dmtst. |
2002-02-27 |
2023-08-12 |
rat |
| Q Wu, M E Reith, R M Wightman, K T Kawagoe, P A Garri. Determination of release and uptake parameters from electrically evoked dopamine dynamics measured by real-time voltammetry. Journal of neuroscience methods. vol 112. issue 2. 2002-02-08. PMID:11716947. |
the two analyses are also compared with an experimental data set describing the effects of pharmacologically inhibiting the da transporter in the caudate-putamen (cp) and nucleus accumbens (nac). |
2002-02-08 |
2023-08-12 |
Not clear |
| F I Tarazi, K Zhang, R J Baldessarin. Long-term effects of olanzapine, risperidone, and quetiapine on dopamine receptor types in regions of rat brain: implications for antipsychotic drug treatment. The Journal of pharmacology and experimental therapeutics. vol 297. issue 2. 2001-05-21. PMID:11303062. |
olanzapine and risperidone, but not quetiapine, significantly increased d(2) binding in medial prefrontal cortex (mpc; 67% and 34%), caudate-putamen (cpu; average 42%, 25%), nucleus accumbens (nac; 37%, 28%), and hippocampus (hip; 53%, 30%). |
2001-05-21 |
2023-08-12 |
rat |
| V David, L H Gold, G F Koob, P Cazal. Anxiogenic-like effects limit rewarding effects of cocaine in balb/cbyj mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 3. 2001-04-19. PMID:11166520. |
to test the hypothesis that injections directly into a reward-relevant brain region might support consistent cocaine-seeking behavior, balb/cbyj mice implanted in the nucleus accumbens (nac) or the caudate-putamen nucleus (cpu) were trained to discriminate between the arm enabling a microinjection of cocaine (30 pmol/50 nl or 150 pmol/50 nl) and the neutral arm of a y-maze. |
2001-04-19 |
2023-08-12 |
mouse |