| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T P Giordano, S S Satpute, J Striessnig, B E Kosofsky, A M Rajadhyaksh. Up-regulation of dopamine D(2)L mRNA levels in the ventral tegmental area and dorsal striatum of amphetamine-sensitized C57BL/6 mice: role of Ca(v)1.3 L-type Ca(2+) channels. Journal of neurochemistry. vol 99. issue 4. 2007-01-09. PMID:17026527. |
in this study, we used quantitative real-time pcr to specifically amplify these two splice variants to examine their mrna expression in the dorsal striatum (dstr), nucleus accumbens (nac) and the ventral tegmental area (vta) of amphetamine-sensitized c57bl/6 mice. |
2007-01-09 |
2023-08-12 |
mouse |
| Yan Zhou, Jacob Bendor, Lauren Hofmann, Matthew Randesi, Ann Ho, Mary Jeanne Kree. Mu opioid receptor and orexin/hypocretin mRNA levels in the lateral hypothalamus and striatum are enhanced by morphine withdrawal. The Journal of endocrinology. vol 191. issue 1. 2006-12-29. PMID:17065397. |
in this study, we investigated the effects of acute morphine administration, chronic intermittent escalating-dose morphine administration and spontaneous withdrawal from chronic morphine on mrna levels of mu opioid receptor (mop-r), and the opioid peptides pro-opiomelanocortin (pomc) and preprodynorphin (ppdyn) in several key brain regions of the rat, associated with drug reward and motivated behaviors: lateral hypothalamus (lat.hyp), nucleus accumbens (nac) core, amygdala, and caudate-putamen (cpu). |
2006-12-29 |
2023-08-12 |
rat |
| Jennifer M Bossert, Sarah M Gray, Lin Lu, Yavin Shaha. Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16341024. |
after extinction of responding, ly379268 was injected to different groups of rats into the nac core or shell or into the caudate-putamen, a terminal region of the nigrastriatal dopamine system. |
2006-11-01 |
2023-08-12 |
rat |
| Jennifer M Bossert, Sarah M Gray, Lin Lu, Yavin Shaha. Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16341024. |
injections of ly379268 (3.0 microg) 1.5 mm dorsal from the nac core into the caudate-putamen were ineffective. |
2006-11-01 |
2023-08-12 |
rat |
| Jesse R Schank, Rossella Ventura, Stefano Puglisi-Allegra, Antonio Alcaro, Charlene D Cole, L Cameron Liles, Philip Seeman, David Weinshenke. Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16395294. |
basal extracellular da levels were significantly attenuated in the nucleus accumbens (nac) and caudate putamen (cp), but not prefrontal cortex (pfc), of dbh-/- mice, while amphetamine-induced da release was absent in the nac and attenuated in the cp and pfc. |
2006-11-01 |
2023-08-12 |
mouse |
| Taylor Moran-Gates, Carla Massari, Amaury Graulich, Jean-François Liégeois, Frank I Taraz. Long-term effects of JL 13, a potential atypical antipsychotic, on rat dopamine and serotonin receptor subtypes. Journal of neuroscience research. vol 84. issue 3. 2006-11-01. PMID:16810690. |
similar to other typical and atypical antipsychotics, jl 13 increased labeling of d(2) receptors in medial prefrontal cortex (mpc) and hippocampus (hip) and d(4) receptors in nucleus accumbens (nac), caudate-putamen (cpu), and hip. |
2006-11-01 |
2023-08-12 |
rat |
| Tanja Vihavainen, Jelena Mijatovic, T Petteri Piepponen, Raimo K Tuominen, Liisa Ahte. Effect of morphine on locomotor activity and striatal monoamine metabolism in nicotine-withdrawn mice. Behavioural brain research. vol 173. issue 1. 2006-10-12. PMID:16846651. |
in the present study mice withdrawn from a 7-week oral nicotine treatment were administered morphine, following which their locomotor activities were recorded and the concentrations of dopamine, 5-hydroxytryptamine (5-ht), noradrenaline and their metabolites were measured in the caudate putamen (cpu) and nucleus accumbens (nac). |
2006-10-12 |
2023-08-12 |
mouse |
| Mark R Stefani, Bita Moghadda. Rule learning and reward contingency are associated with dissociable patterns of dopamine activation in the rat prefrontal cortex, nucleus accumbens, and dorsal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 34. 2006-09-28. PMID:16928870. |
we measured dopamine release in the prefrontal cortex (pfc), nucleus accumbens (nac), and dorsal striatum (ds) of rats exposed to the same maze apparatus under three behavioral conditions: a set-shift task in which reward depended on discrimination learning and extradimensional set-shifting, a yoked condition in which reward was intermittent and not under the control of the subject, and a "reward-retrieval" variant in which reward was certain on every trial. |
2006-09-28 |
2023-08-12 |
human |
| Peter Olausson, J David Jentsch, Natalie Tronson, Rachel L Neve, Eric J Nestler, Jane R Taylo. DeltaFosB in the nucleus accumbens regulates food-reinforced instrumental behavior and motivation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 36. 2006-09-26. PMID:16957076. |
repeated exposure to drugs of abuse or stress is known to persistently induce the transcription factor deltafosb in the nucleus accumbens (nac) and dorsal striatum, effects hypothesized to contribute to neuroadaptations in dopamine-regulated signaling. |
2006-09-26 |
2023-08-12 |
mouse |
| Zheng-Xiong Xi, Jeremy G Gilbert, Xiao-Qing Peng, Arlene C Pak, Xia Li, Eliot L Gardne. Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 33. 2006-09-12. PMID:16914679. |
local perfusion of am251 into the nac or the dorsal striatum also inhibited cocaine-triggered reinstatement. |
2006-09-12 |
2023-08-12 |
rat |
| Lina Yao, Krista McFarland, Peidong Fan, Zhan Jiang, Takashi Ueda, Ivan Diamon. Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 20. 2006-07-28. PMID:16684876. |
opiate and cb1 receptors are coexpressed in the nucleus accumbens (nac) and dorsal striatum. |
2006-07-28 |
2023-08-12 |
human |
| Malini E Singh, Iain S McGregor, Paul E Malle. Perinatal exposure to delta(9)-tetrahydrocannabinol alters heroin-induced place conditioning and fos-immunoreactivity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 1. 2006-05-12. PMID:15920503. |
acute administration of heroin in vehicle pretreated rats increased fos-ir in the central, medial, and dorsomedial caudate putamen (cpu), nucleus accumbens (nac, core and shell regions), lateral septum, islands of calleja-major (icjm), bed nucleus of the stria terminalis (bnst), central nucleus of the amygdala (cea), dorsolateral and dorsomedial periaqueductal gray (pag), ventral tegmental area (vta), edinger-westphal nucleus (ew). |
2006-05-12 |
2023-08-12 |
rat |
| Taylor Moran-Gates, Lu Gan, Young Shik Park, Kehong Zhang, Ross J Baldessarini, Frank I Taraz. Repeated antipsychotic drug exposure in developing rats: dopamine receptor effects. Synapse (New York, N.Y.). vol 59. issue 2. 2006-04-05. PMID:16270300. |
fluphenazine and olanzapine, but not clozapine, also increased d2 receptor levels in hippocampus, and d4 levels in nucleus accumbens (nac) and caudate-putamen (cpu) in both juvenile and adult brain. |
2006-04-05 |
2023-08-12 |
rat |
| Venetia Zachariou, Carlos A Bolanos, Dana E Selley, David Theobald, Michael P Cassidy, Max B Kelz, Tamara Shaw-Lutchman, Olivier Berton, Laura J Sim-Selley, Ralph J Dileone, Arvind Kumar, Eric J Nestle. An essential role for DeltaFosB in the nucleus accumbens in morphine action. Nature neuroscience. vol 9. issue 2. 2006-03-29. PMID:16415864. |
the transcription factor deltafosb is induced in the nucleus accumbens (nac) and dorsal striatum by the repeated administration of drugs of abuse. |
2006-03-29 |
2023-08-12 |
mouse |
| Venetia Zachariou, Carlos A Bolanos, Dana E Selley, David Theobald, Michael P Cassidy, Max B Kelz, Tamara Shaw-Lutchman, Olivier Berton, Laura J Sim-Selley, Ralph J Dileone, Arvind Kumar, Eric J Nestle. An essential role for DeltaFosB in the nucleus accumbens in morphine action. Nature neuroscience. vol 9. issue 2. 2006-03-29. PMID:16415864. |
we achieved overexpression of deltafosb by using a bitransgenic mouse line that inducibly expresses the protein in the nac and dorsal striatum and by using viral-mediated gene transfer to specifically express the protein in the nac. |
2006-03-29 |
2023-08-12 |
mouse |
| Yan Pan, Ermanda Siregar, Kenneth D Car. Striatal cell signaling in chronically food-restricted rats under basal conditions and in response to brief handling. Neuroscience letters. vol 393. issue 2-3. 2006-03-14. PMID:16239070. |
using western blotting it was found that basal phospho-jnk is higher in caudate-putamen (cpu) and nac of fr relative to al rats. |
2006-03-14 |
2023-08-12 |
human |
| Eugene D Festa, Shirzad Jenab, Jan Weiner, Arbi Nazarian, Tipyamol Niyomchai, Scott J Russo, Lynne M Kemen, Alaleh Akhavan, Hui-Bing K Wu, Vanya Quinones-Jena. Cocaine-induced sex differences in D1 receptor activation and binding levels after acute cocaine administration. Brain research bulletin. vol 68. issue 4. 2006-03-08. PMID:16377433. |
there were no sex differences in baseline levels of d1, d2, and da transporter binding in the caudate putamen (cpu) and the nucleus accumbens (nac). |
2006-03-08 |
2023-08-12 |
rat |
| Scott E Hemby, Brian Horman, Wenxue Tan. Differential regulation of ionotropic glutamate receptor subunits following cocaine self-administration. Brain research. vol 1064. issue 1-2. 2006-03-07. PMID:16277980. |
western blotting was used to compare levels of iglur protein expression (nr1-3b, glur1-7, ka2) in the mesolimbic (ventral tegmental area, vta; nucleus accumbens, nac; and prefrontal cortex, pfc) and nigrostriatal pathways (substantia nigra, sn and dorsal caudate-putamen, cpu). |
2006-03-07 |
2023-08-12 |
Not clear |
| Teodoro Zornoza, María J Cano-Cebrián, Fernando Martínez-García, Ana Polache, Luis Graner. Hippocampal dopamine receptors modulate cFos expression in the rat nucleus accumbens evoked by chemical stimulation of the ventral hippocampus. Neuropharmacology. vol 49. issue 7. 2006-01-30. PMID:16040065. |
in the present study we analyze the possible role of vh d1 and d2 receptors in the modulation of the cfos expression in nac (core and shell subregions) and in dorsal striatum. |
2006-01-30 |
2023-08-12 |
rat |
| Teodoro Zornoza, María J Cano-Cebrián, Fernando Martínez-García, Ana Polache, Luis Graner. Hippocampal dopamine receptors modulate cFos expression in the rat nucleus accumbens evoked by chemical stimulation of the ventral hippocampus. Neuropharmacology. vol 49. issue 7. 2006-01-30. PMID:16040065. |
no statistically significant increases were observed in the nac core and in the dorsal striatum. |
2006-01-30 |
2023-08-12 |
rat |