| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M E Singh, I S McGregor, P E Malle. Repeated exposure to Delta(9)-tetrahydrocannabinol alters heroin-induced locomotor sensitisation and Fos-immunoreactivity. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16137723. |
acute heroin increased fos-ir in drug-naïve rats in the caudate-putamen (cpu; central, medial and dorsomedial regions), nucleus accumbens (nac; core and shell regions), bed nucleus of the stria terminalis (bnst), lateral septum, central nucleus of the amygdala (cea), periaqueductal grey (pag; dorsolateral, dorsomedial, and lateral), and the edinger-westphal nucleus. |
2006-01-17 |
2023-08-12 |
rat |
| Yan Pan, Yemiliya Berman, Kenneth D Car. Effects of the group I metabotropic glutamate receptor agonist, DHPG, and injection stress on striatal cell signaling in food-restricted and ad libitum fed rats. BMC neuroscience. vol 5. 2005-12-20. PMID:15579204. |
chronic food restriction augments the rewarding effect of centrally administered psychostimulant drugs and this effect may involve a previously documented upregulation of d-1 dopamine receptor-mediated map kinase signaling in nucleus accumbens (nac) and caudate-putamen (cpu). |
2005-12-20 |
2023-08-12 |
rat |
| Stefan D Schlussman, Yan Zhou, Alexis Bailey, Ann Ho, Mary Jeanne Kree. Steady-dose and escalating-dose "binge" administration of cocaine alter expression of behavioral stereotypy and striatal preprodynorphin mRNA levels in rats. Brain research bulletin. vol 67. issue 3. 2005-12-15. PMID:16144651. |
cocaine, independent of dose, increased ppdyn mrna levels in the caudate putamen (cpu), but not in the nucleus accumbens (nac). |
2005-12-15 |
2023-08-12 |
rat |
| Daniel G Smith, Eleni T Tzavara, Janice Shaw, Susan Luecke, Mark Wade, Richard Davis, Craig Salhoff, George G Nomikos, Donald R Gehler. Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 4. 2005-08-31. PMID:15673672. |
tissue contents of dopamine within the nac and caudate-putamen were not significantly different in ko compared with wt mice. |
2005-08-31 |
2023-08-12 |
mouse |
| Elena Butovsky, Ana Juknat, Igor Goncharov, Judith Elbaz, Raya Eilam, Abraham Zangen, Zvi Voge. In vivo up-regulation of brain-derived neurotrophic factor in specific brain areas by chronic exposure to Delta-tetrahydrocannabinol. Journal of neurochemistry. vol 93. issue 4. 2005-07-05. PMID:15857384. |
immunohistochemistry showed large increases in bdnf-stained cells in the nac (5.5-fold), posterior vta (4-fold) and pvn (1.7-fold), but no change was observed in the anterior vta, hippocampus or dorsal striatum. |
2005-07-05 |
2023-08-12 |
rat |
| Shu-Peng Li, Moon Seok Park, Jong Hun Kim, Myeong Ok Ki. Chronic nicotine and smoke treatment modulate dopaminergic activities in ventral tegmental area and nucleus accumbens and the gamma-aminobutyric acid type B receptor expression of the rat prefrontal cortex. Journal of neuroscience research. vol 78. issue 6. 2005-03-07. PMID:15521060. |
to explore further the relationship between the mesencephalic dopaminergic neurons and pfc gabaergic neurons, we investigated the effects of nicotine and passive exposure to cigarette smoke on the regulation of tyrosine hydroxylase (th) in vta and substantia nigra (snc) and dopamine (da) d1 receptor levels in nucleus accumbens (nac) and caudate-putamen (cpu). |
2005-03-07 |
2023-08-12 |
rat |
| Mikko Airavaara, Anu Planken, Helena Gäddnäs, Timo Petteri Piepponen, Mart Saarma, Liisa Ahte. Increased extracellular dopamine concentrations and FosB/DeltaFosB expression in striatal brain areas of heterozygous GDNF knockout mice. The European journal of neuroscience. vol 20. issue 9. 2005-03-04. PMID:15525275. |
unexpectedly the extracellular dopamine concentration in the gdnf+/- mice in the dorsal striatum (cpu) was 2.0-fold, and in the nucleus accumbens (nac) 1.6-fold the concentration found in the wild-type littermates. |
2005-03-04 |
2023-08-12 |
mouse |
| Jesus A Angulo, Nieves Angulo, Jing Y. Antagonists of the neurokinin-1 or dopamine D1 receptors confer protection from methamphetamine on dopamine terminals of the mouse striatum. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542715. |
exposure to meth induces long-term deficits in dopamine transporter (dat) and tyrosine hydroxylase (th) levels as well as induction of glial fibrillary acidic protein (gfap) in the caudate putamen (cpu) and the nucleus accumbens (nac). |
2005-02-18 |
2023-08-12 |
mouse |
| Nan Zeng, Akira Nakajima, Jue He, Atsumi Nitta, Kiyofumi Yamada, Toshitaka Nabeshim. Fos expression associated with the discriminative stimulus effects of methamphetamine in rats. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542722. |
c-fos expression in the brains of rats trained to discriminate methamphetamine from saline was significantly increased in the nucleus accumbens (nac) and the ventral tegmental area (vta) as compared with the expression in the control rats that were maintained under the fr-20 schedule, but no alternation was observed in other areas including the cerebral cortex, caudate putamen, substantia nigra, hippocampus, amygdala, and habenulla. |
2005-02-18 |
2023-08-12 |
rat |
| Hao-Wei Shen, Yoko Hagino, Hideaki Kobayashi, Keiko Shinohara-Tanaka, Kazutaka Ikeda, Hideko Yamamoto, Toshifumi Yamamoto, Klaus-Peter Lesch, Dennis L Murphy, F Scott Hall, George R Uhl, Ichiro Sor. Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 10. 2004-11-22. PMID:15226739. |
to help determine mechanisms underlying these effects, we now report examination of baselines and drug-induced changes of extracellular dopamine (daex) and serotonin (5-ht(ex)) levels in microdialysates from nucleus accumbens (nac), caudate putamen (cpu), and prefrontal cortex (pfc) of wild-type, homozygous dat- or sert-ko and heterozygous or homozygous dat/sert double-ko mice, which are differentially rewarded by cocaine. |
2004-11-22 |
2023-08-12 |
mouse |
| Akira Nakajima, Kiyofumi Yamada, Jue He, Nan Zeng, Atsumi Nitta, Toshitaka Nabeshim. Anatomical substrates for the discriminative stimulus effects of methamphetamine in rats. Journal of neurochemistry. vol 91. issue 2. 2004-11-15. PMID:15447664. |
fos expression in the brains of rats that discriminate methamphetamine from saline was significantly increased in the nucleus accumbens (nac) and the ventral tegmental area (vta), but not in other areas including the cerebral cortex, caudate putamen, substantia nigra, hippocampus, amygdala and habenulla, as compared with the expression in control rats that were maintained under the fr-20 schedule. |
2004-11-15 |
2023-08-12 |
rat |
| S Scheggi, R Rauggi, C Gambarana, A Tagliamonte, M G De Monti. Dopamine and cyclic AMP-regulated phosphoprotein-32 phosphorylation pattern in cocaine and morphine-sensitized rats. Journal of neurochemistry. vol 90. issue 4. 2004-10-28. PMID:15287884. |
cocaine-sensitized rats showed increased phosphorylation of dopamine- and cyclic amp-regulated phosphoprotein mr 32 kda (darpp-32) at threonine-75 (thr75) and decreased darpp-32 phosphorylation at thr34, in the caudate-putamen (cpu) and nucleus accumbens (nac) 7 days after sensitization assessment. |
2004-10-28 |
2023-08-12 |
rat |
| M S Todtenkopf, J R Stellar, E A Williams, D S Zah. Differential distribution of parvalbumin immunoreactive neurons in the striatum of cocaine sensitized rats. Neuroscience. vol 127. issue 1. 2004-10-14. PMID:15219666. |
the dorsal striatum and the nucleus accumbens (nac) have been shown to play an integral role in this phenomenon. |
2004-10-14 |
2023-08-12 |
rat |
| Andreas Leng, Joram Feldon, Boris Ferge. Long-term social isolation and medial prefrontal cortex: dopaminergic and cholinergic neurotransmission. Pharmacology, biochemistry, and behavior. vol 77. issue 2. 2004-09-28. PMID:14751467. |
thus, a postmortem micropunch analysis measuring dopamine (da), dopac (3,4-dihydroxyphenylacetic acid) and homovanillic acid (hva) in the dorsal and ventral subregion of the mpfc, the caudate putamen (cpu) and nucleus accumbens (nac) was carried out on socially isolated or group-housed male sprague-dawley (sd) rats. |
2004-09-28 |
2023-08-12 |
rat |
| Alex V Yarkov, Diane Hanger, Maria Reploge, Jeffrey N Joyc. Behavioral effects of dopamine agonists and antagonists in MPTP-lesioned D3 receptor knockout mice. Pharmacology, biochemistry, and behavior. vol 76. issue 3-4. 2004-08-24. PMID:14643855. |
mptp treatment produced equivalent 70% losses of dopamine fibers in the caudate putamen (cpu) and nucleus accumbens (nac) of wt and d(3) ko mice as compared to their control (vehicle injected) counterparts. |
2004-08-24 |
2023-08-12 |
mouse |
| Lu Gan, Tomas L Falzone, Kehong Zhang, Marcelo Rubinstein, Ross J Baldessarini, Frank I Taraz. Enhanced expression of dopamine D(1) and glutamate NMDA receptors in dopamine D(4) receptor knockout mice. Journal of molecular neuroscience : MN. vol 22. issue 3. 2004-06-17. PMID:14997010. |
labeling of d1 receptors was significantly increased in nucleus accumbens (nac; 39%) and caudate putamen (cpu; 42%) of d4-knockout mice vs wild-type controls. |
2004-06-17 |
2023-08-12 |
mouse |
| S L Haberny, Y Berman, E Meller, K D Car. Chronic food restriction increases D-1 dopamine receptor agonist-induced phosphorylation of extracellular signal-regulated kinase 1/2 and cyclic AMP response element-binding protein in caudate-putamen and nucleus accumbens. Neuroscience. vol 125. issue 1. 2004-06-03. PMID:15051167. |
the purpose of the present study was to determine whether d-1 da receptor binding and/or mitogen-activated protein kinase (mapk) signaling in caudate-putamen (cpu) and nucleus accumbens (nac) are increased in food-restricted subjects. |
2004-06-03 |
2023-08-12 |
human |
| Konrad Lehmann, Jörg Lesting, Dierk Polascheck, Gertraud Teuchert-Nood. Serotonin fibre densities in subcortical areas: differential effects of isolated rearing and methamphetamine. Brain research. Developmental brain research. vol 147. issue 1-2. 2004-05-03. PMID:14741759. |
we therefore checked for anatomical effects of both interventions by immunohistochemically staining serotonin fibres and assessing fibre densities in the caudate-putamen (cpu), nucleus accumbens (nac) and amygdala of mongolian gerbils. |
2004-05-03 |
2023-08-12 |
Not clear |
| E M Nikulina, H E Covington, L Ganschow, R P Hammer, K A Micze. Long-term behavioral and neuronal cross-sensitization to amphetamine induced by repeated brief social defeat stress: Fos in the ventral tegmental area and amygdala. Neuroscience. vol 123. issue 4. 2004-04-12. PMID:14751279. |
amphetamine augmented stress-induced fos-li labeling 17 days after the first stress episode in the dorsal striatum, nac core, and medial amygdala, reflecting a cross-sensitization of fos response. |
2004-04-12 |
2023-08-12 |
rat |
| G N Neigh, H M Arnold, R L Rabenstein, M Sarter, J P Brun. Neuronal activity in the nucleus accumbens is necessary for performance-related increases in cortical acetylcholine release. Neuroscience. vol 123. issue 3. 2004-03-31. PMID:14706776. |
upon reaching a consistent level of performance, rats were implanted with microdialysis cannula in the medial prefrontal cortex (mpfc) and either the ipsilateral shell of the nac or in the dorsal striatum (str; control site). |
2004-03-31 |
2023-08-12 |
rat |