All Relations between dorsal striatum and nac

Publication Sentence Publish Date Extraction Date Species
Y Lei, S M Tejani-But. N-methyl-d-aspartic acid receptors are altered by stress and alcohol in Wistar-Kyoto rat brain. Neuroscience. vol 169. issue 1. 2011-03-04. PMID:20466039. thus this study measured the binding of [(3)h] mk-801 to nmda receptors in the prefrontal cortex (pfc), caudate putamen (cpu), nucleus accumbens (nac), hippocampus (hip) and basolateral amygdala (bla) in wky rats in comparison to the wistar (wis) rat strain. 2011-03-04 2023-08-12 rat
K K Pitchers, K S Frohmader, V Vialou, E Mouzon, E J Nestler, M N Lehman, L M Coole. ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual reward. Genes, brain, and behavior. vol 9. issue 7. 2011-02-08. PMID:20618447. sexual experience was shown to cause Δfosb accumulation in several limbic brain regions including the nucleus accumbens (nac), medial prefrontal cortex, ventral tegmental area and caudate putamen but not the medial preoptic nucleus. 2011-02-08 2023-08-12 rat
Erin B Larson, Fatih Akkentli, Scott Edwards, Danielle L Graham, Diana L Simmons, Imran N Alibhai, Eric J Nestler, David W Sel. Striatal regulation of ΔFosB, FosB, and cFos during cocaine self-administration and withdrawal. Journal of neurochemistry. vol 115. issue 1. 2010-10-13. PMID:20633205. we found that cfos, fosb, and Δfosb exhibit regionally and temporally distinct expression patterns, with greater accumulation of Δfosb protein in the nucleus accumbens (nac) shell and core after chronic cocaine administration, whereas Δfosb increases in the caudate-putamen (cpu) remained similar with either acute or chronic administration. 2010-10-13 2023-08-12 rat
Xia Li, Jie Li, Eliot L Gardner, Zheng-Xiong X. Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in rats. Journal of neurochemistry. vol 114. issue 5. 2010-09-13. PMID:20534005. intracranial microinjections of amn082 into the nucleus accumbens (nac) or ventral pallidum, but not the dorsal striatum, also inhibited cocaine-primed reinstatement, an effect that was blocked by local co-administration of mmpip, a selective mglur7 antagonist. 2010-09-13 2023-08-12 rat
Xia Li, Jie Li, Eliot L Gardner, Zheng-Xiong X. Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in rats. Journal of neurochemistry. vol 114. issue 5. 2010-09-13. PMID:20534005. in vivo microdialysis demonstrated that cocaine priming significantly increased extracellular dopamine in the nac, ventral pallidum and dorsal striatum, while increasing extracellular glutamate in the nac only. 2010-09-13 2023-08-12 rat
Z Ren, W L Sun, H Jiao, D Zhang, H Kong, X Wang, M X. Dopamine D1 and N-methyl-D-aspartate receptors and extracellular signal-regulated kinase mediate neuronal morphological changes induced by repeated cocaine administration. Neuroscience. vol 168. issue 1. 2010-08-20. PMID:20346392. changes in dendritic morphology in medium spiny neurons (msns) in the nucleus accumbens (nac) and caudate putamen (cpu) accompany drug-induced enduring behavioral and molecular changes. 2010-08-20 2023-08-12 Not clear
Milena Moretti, Manolo Mugnaini, Michela Tessari, Michele Zoli, Annalisa Gaimarri, Irene Manfredi, Francesco Pistillo, Francesco Clementi, Cecilia Gott. A comparative study of the effects of the intravenous self-administration or subcutaneous minipump infusion of nicotine on the expression of brain neuronal nicotinic receptor subtypes. Molecular pharmacology. vol 78. issue 2. 2010-08-03. PMID:20439469. in the mp group, alpha4beta2 nachrs were up-regulated in all brain regions, alpha6beta2* nachrs were down-regulated in the nucleus accumbens (nac) and caudate-putamen, and alpha7 nachrs were up-regulated in the caudal cerebral cortex (ccx); the up-regulation of alpha4beta2alpha5 nachrs in the ccx was also suggested. 2010-08-03 2023-08-12 rat
Garret D Stuber, Thomas S Hnasko, Jonathan P Britt, Robert H Edwards, Antonello Bonc. Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 24. 2010-07-02. PMID:20554874. these results provide definitive physiological evidence for vglut2-mediated glutamate release by mature dopamine neurons projecting to the nac shell, but not to the dorsal striatum. 2010-07-02 2023-08-12 mouse
Irene Yaroslavsky, Shanaz M Tejani-But. Voluntary alcohol consumption alters stress-induced changes in dopamine-2 receptor binding in Wistar-Kyoto rat brain. Pharmacology, biochemistry, and behavior. vol 94. issue 3. 2010-03-23. PMID:19896970. quantitative autoradiography experiments showed that chronic stress increased d2 receptor binding in the caudate putamen (cpu), nucleus accumbens (nac), substantia nigra (sn) and ventral tegmental area (vta) of wky rats, and reduced receptor binding in the cpu and sn of wis rats. 2010-03-23 2023-08-12 rat
Joshua W Cordeira, Lauren Frank, Miguel Sena-Esteves, Emmanuel N Pothos, Maribel Rio. Brain-derived neurotrophic factor regulates hedonic feeding by acting on the mesolimbic dopamine system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 7. 2010-03-19. PMID:20164338. moreover, amperometric recordings in brain slices of mice depleted of central bdnf uncovered marked deficits in evoked release of dopamine in the nucleus accumbens (nac) shell and dorsal striatum but normal secretion in the nac core. 2010-03-19 2023-08-12 mouse
Zheng-Xiong Xi, Xia Li, Xiao-Qing Peng, Jie Li, Lauren Chun, Eliot L Gardner, Ajit G Thomas, Barbara S Slusher, Charles R Ashb. Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism. Journal of neurochemistry. vol 112. issue 2. 2010-02-05. PMID:19895667. microinjections of 2-pmpa (3-5 microg/side) or naag (3-5 microg/side) into the nucleus accumbens (nac), but not into the dorsal striatum, also inhibited cocaine-induced reinstatement, an effect that was blocked by intra-nac injection of ly341495, a selective mglur2/3 antagonist. 2010-02-05 2023-08-12 rat
Mary Kay Lob. Molecular profiling of striatonigral and striatopallidal medium spiny neurons past, present, and future. International review of neurobiology. vol 89. 2010-01-25. PMID:19900613. the two msn populations are morphologically identical except in their projections through the direct verses indirect bg pathways and they are heterogeneously dispersed throughout the dorsal striatum (dstr) and nucleus accumbens (nac). 2010-01-25 2023-08-12 mouse
Anna M Nelson, Gaynor A Larson, Nancy R Zahnise. Low or high cocaine responding rats differ in striatal extracellular dopamine levels and dopamine transporter number. The Journal of pharmacology and experimental therapeutics. vol 331. issue 3. 2009-12-22. PMID:19729579. paralleling their locomotor profiles, lcrs and hcrs had similar basal extracellular da levels in dorsal striatum (dstr) and nucleus accumbens (nac); after acute cocaine injection (10 mg/kg i.p. 2009-12-22 2023-08-12 rat
Michael W Shiflett, Jocelyn C Mauna, Amanda M Chipman, Eloise Peet, Edda Thiel. Appetitive Pavlovian conditioned stimuli increase CREB phosphorylation in the nucleus accumbens. Neurobiology of learning and memory. vol 92. issue 3. 2009-11-05. PMID:19248836. we found that repeated tone-food pairings resulted in an increase in creb phosphorylation in the nac but not in the adjacent dorsal striatum or in the nac 3h after the final training session. 2009-11-05 2023-08-12 rat
Feng Shao, Jian Jin, Qingxuan Meng, Mei Liu, Xi Xie, Wenjuan Lin, Weiwen Wan. Pubertal isolation alters latent inhibition and DA in nucleus accumbens of adult rats. Physiology & behavior. vol 98. issue 3. 2009-10-27. PMID:19527740. after the behavioral test, dopamine (da) levels were measured in the medial prefrontal cortex (mpfc), nucleus accumbens (nac), caudate-putamen (cpu), and the hippocampus (hip). 2009-10-27 2023-08-12 rat
J Weiner, W Lun Sun, L Zhou, C M Kreiter, S Jenab, V Quiñones-Jena. PKA-mediated responses in females' estrous cycle affect cocaine-induced responses in dopamine-mediated intracellular cascades. Neuroscience. vol 161. issue 3. 2009-08-24. PMID:19348873. the nucleus accumbens (nac) and caudate putamen (cpu) were dissected and analyzed via western blot for total and phosphorylated (p-thr34) dopamine- and 3'-5'-cyclic amp-regulated phosphoprotein with molecular weight 32 kda (darpp-32), pp1, pp2b (cna1 and cnb1 subunits), pka, creb, cfos, and delta-fosb. 2009-08-24 2023-08-12 rat
Xia Li, Jie Li, Xiao-Qing Peng, Krista Spiller, Eliot L Gardner, Zheng-Xiong X. Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 7. 2009-08-03. PMID:19158667. microinjections of amn082 (1-5 microg/microl per side) into the nucleus accumbens (nac) or ventral pallidum (vp), but not dorsal striatum, also inhibited cocaine self-administration in a dose-dependent manner. 2009-08-03 2023-08-12 rat
Gero Falkenstein, Christoph Rosenthal, Torsten Reum, Rudolf Morgenstern, Máté Döbrössy, Guido Nikkha. Pattern of long-term sensorimotor recovery following intrastriatal and--accumbens DA micrografts in a rat model of Parkinson's disease. The Journal of comparative neurology. vol 515. issue 1. 2009-07-28. PMID:19399892. here we investigated two implantation sites, the nucleus accumbens (nac) and the caudate-putamen unit (cpu), and two different graft distributions within the cpu, i.e., two 0.75 microl deposits (cpu-2) versus six 0.25 microl deposits (cpu-6) in a rat model of pd. 2009-07-28 2023-08-12 rat
Frank I Tarazi, Yong Kee Choi, Matthew Gardner, Erik H F Wong, Brian Henry, Mohammed Shahi. Asenapine exerts distinctive regional effects on ionotropic glutamate receptor subtypes in rat brain. Synapse (New York, N.Y.). vol 63. issue 5. 2009-06-17. PMID:19177511. brain sections were collected from the medial prefrontal cortex (mpfc), dorsolateral frontal cortex, caudate putamen (cpu), nucleus accumbens (nac), and hippocampus (hip), and processed for in vitro receptor autoradiography. 2009-06-17 2023-08-12 human
Tianxiang Zhang, Lifen Zhang, Yong Liang, Athanassios G Siapas, Fu-Ming Zhou, John A Dan. Dopamine signaling differences in the nucleus accumbens and dorsal striatum exploited by nicotine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 13. 2009-04-23. PMID:19339599. the dorsal striatum and the nucleus accumbens (nac) shell of the ventral striatum have similar cellular components and are both richly innervated by dopamine neurons. 2009-04-23 2023-08-12 rat