| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rafael Renteria, Zachary M Jeanes, Richard A Morriset. Ethanol attenuation of long-term depression in the nucleus accumbens can be overcome by activation of TRPV1 receptors. Alcoholism, clinical and experimental research. vol 38. issue 11. 2015-07-20. PMID:25421513. |
we have previously reported that n-methyl-d-aspartate receptor (nmdar)-dependent long-term depression (ltd) is markedly affected by chronic intermittent ethanol exposure in vivo; however, endocannabinoid (ecb)-dependent synaptic depression, despite being very well-documented in the dorsal striatum, is much less well understood in the nac. |
2015-07-20 |
2023-08-13 |
Not clear |
| Haiyin Wu, Brian O'Neill, Dawn D Han, Keerthi Thirtamara-Rajamani, Yanlin Wang, Howard H G. Restoration of cocaine stimulation and reward by reintroducing wild type dopamine transporter in adult knock-in mice with a cocaine-insensitive dopamine transporter. Neuropharmacology. vol 86. 2015-07-14. PMID:24835281. |
in an earlier study we showed that aav-datwt injections in regions covering the lateral nucleus accumbens (nac) and lateral caudate-putamen (cpu) restored cocaine stimulation but not cocaine reward. |
2015-07-14 |
2023-08-13 |
mouse |
| Yoshiaki Miyamoto, Yudai Ishikawa, Noriyuki Iegaki, Kazuyuki Sumi, Kequan Fu, Keiji Sato, Yoko Furukawa-Hibi, Shin-Ichi Muramatsu, Toshitaka Nabeshima, Kyosuke Uno, Atsumi Nitt. Overexpression of Shati/Nat8l, an N-acetyltransferase, in the nucleus accumbens attenuates the response to methamphetamine via activation of group II mGluRs in mice. The international journal of neuropsychopharmacology. vol 17. issue 8. 2015-04-14. PMID:24559655. |
in this study, we injected adeno-associated virus (aav) vector containing shati/nat8l into the nac or dorsal striatum (ds) of mice, to increase shati/nat8l expression. |
2015-04-14 |
2023-08-12 |
mouse |
| Zhenzhen Hu, Eun-Hye Oh, Yeon Bok Chung, Jin Tae Hong, Ki-Wan O. Predominant D1 Receptors Involvement in the Over-expression of CART Peptides after Repeated Cocaine Administration. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 19. issue 2. 2015-03-02. PMID:25729269. |
a higher proportion of cart(+) cells in the cocaine-treated mice were present in the nucleus accumbens (nac) shell than in the dorsolateral (dl) part of caudate putamen (cp). |
2015-03-02 |
2023-08-13 |
mouse |
| Yu-Jun Wang, Peng Huang, Julie A Blendy, Lee-Yuan Liu-Che. Brain region- and sex-specific alterations in DAMGO-stimulated [(35) S]GTPγS binding in mice with Oprm1 A112G. Addiction biology. vol 19. issue 3. 2014-12-16. PMID:22862850. |
in g/g mice, males showed higher damgo-stimulated [(35) s]gtpγs binding than females in the cingulate cortex, caudate putamen, nac core, thalamus and amygdala. |
2014-12-16 |
2023-08-12 |
mouse |
| Pei-Ching Chang, Sarah Lynn Pollema-Mays, Maria Virginia Centeno, Daniel Procissi, Massimo Contini, Alex Tomas Baria, Marco Martina, Apkar Vania Apkaria. Role of nucleus accumbens in neuropathic pain: linked multi-scale evidence in the rat transitioning to neuropathic pain. Pain. vol 155. issue 6. 2014-12-15. PMID:24607959. |
we observed interrelated changes: (1) in resting-state functional magnetic resonance imaging (fmri), functional connectivity of the nac to dorsal striatum and cortex was reduced 28days (but not 5days) after sni; (2) contralateral to sni injury, gene expression of nac dopamine 1a, 2, and κ-opioid receptors decreased 28days after sni; (3) in sni (but not sham), covariance of gene expression was upregulated at 5days and settled to a new state at 28days; and (4) nac functional connectivity correlated with dopamine receptor gene expression and with tactile allodynia. |
2014-12-15 |
2023-08-12 |
rat |
| Ning Wang, Ping Su, Ying Zhang, Jie Lu, Baoming Xing, Kai Kang, Wenqi Li, Yun Wan. Protein kinase D1-dependent phosphorylation of dopamine D1 receptor regulates cocaine-induced behavioral responses. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 5. 2014-12-01. PMID:24362306. |
importantly, injection of the peptide tat-s421, an engineered tat fusion-peptide targeting s421 (tat-s421), into the rat dorsal striatum inhibits cocaine-induced locomotor hyperactivity and injection of tat-s421 into the rat hippocampus or the shell of the nucleus accumbens (nac) also inhibits cocaine-induced conditioned place preference (cpp). |
2014-12-01 |
2023-08-12 |
rat |
| Natalie E Zlebnik, Valerie L Hedges, Marilyn E Carroll, Robert L Meise. Chronic wheel running affects cocaine-induced c-Fos expression in brain reward areas in rats. Behavioural brain research. vol 261. 2014-10-06. PMID:24342748. |
the c-fos transcription factor is a measure of cellular activity and was used to quantify cocaine-induced activation of reward-processing areas of the brain: nucleus accumbens (nac), caudate putamen (cpu), medial prefrontal cortex (mpfc), and orbitofrontal cortex (ofc). |
2014-10-06 |
2023-08-12 |
human |
| N Zhao, Y Chen, J Zhu, L Wang, G Cao, Y Dang, C Yan, J Wang, T Che. Levo-tetrahydropalmatine attenuates the development and expression of methamphetamine-induced locomotor sensitization and the accompanying activation of ERK in the nucleus accumbens and caudate putamen in mice. Neuroscience. vol 258. 2014-09-29. PMID:24269936. |
therefore, the current study aims to examine the roles of l-thp in the development and expression of meth-induced locomotor sensitization as well as the accompanying extracellular-regulated kinase (erk) activation in the nucleus accumbens (nac), caudate putamen (cpu) and prefrontal cortex (pfc) in mice. |
2014-09-29 |
2023-08-12 |
mouse |
| Xuekun Ding, Yanhua Qiao, Chengji Piao, Xigeng Zheng, Zhengkui Liu, Jing Lian. N-methyl-D-aspartate receptor-mediated glutamate transmission in nucleus accumbens plays a more important role than that in dorsal striatum in cognitive flexibility. Frontiers in behavioral neuroscience. vol 8. 2014-09-24. PMID:25249952. |
these findings suggest that nmdar-mediated glutamate transmission in the nac contributes more to cognitive execution compared with the dorsal striatum. |
2014-09-24 |
2023-08-13 |
rat |
| Jing Yuan Ma, Shan Zhi Gu, Min Meng, Yong Hui Dang, Chong Ya Huang, Emmanuel S Onaiv. Regional expression of extracellular signal-regulated kinase 1 and 2 mRNA in a morphine-induced conditioned place preference model. Brain research. vol 1543. 2014-08-18. PMID:24296091. |
in the present study, we investigated the expression of erk messenger ribonucleic acid (mrna) of the prefrontal cortex (pfc), nucleus accumbens (nac), hippocampus, and caudate putamen (cpu) in morphine-induced conditioned place preference (cpp) by real-time reverse transcriptase polymerase chain reaction (real-time pcr). |
2014-08-18 |
2023-08-12 |
Not clear |
| Melissa L Perreault, Theresa Fan, Brian F O'Dowd, Susan R Georg. Enhanced brain-derived neurotrophic factor signaling in the nucleus accumbens of juvenile rats. Developmental neuroscience. vol 35. issue 5. 2014-06-09. PMID:24021607. |
in the present study, we characterized age-dependent differences in bdnf signaling and trkb expression within the nucleus accumbens (nac), caudate putamen (cp) and pfc in rats and determined the effects of administration of the dopamine agonist, skf 83959, which activates the gq-coupled dopamine receptors, the dopamine d5 receptor and the d1-d2 receptor heteromer. |
2014-06-09 |
2023-08-12 |
rat |
| Giuseppe Gangarossa, Julie Espallergues, Alban de Kerchove d'Exaerde, Salah El Mestikawy, Charles R Gerfen, Denis Hervé, Jean-Antoine Girault, Emmanuel Valjen. Distribution and compartmental organization of GABAergic medium-sized spiny neurons in the mouse nucleus accumbens. Frontiers in neural circuits. vol 7. 2014-05-19. PMID:23423476. |
while the functional organization of the nac core outputs resembles the one described for the dorsal striatum, a simple classification of the nac shell neurons has been difficult to define due to the complexity of the compartmental segregation of cells. |
2014-05-19 |
2023-08-12 |
mouse |
| Junran Cao, Jennifer B Dwyer, Nicole M Gautier, Frances M Leslie, Ming D L. Central myelin gene expression during postnatal development in rats exposed to nicotine gestationally. Neuroscience letters. vol 553. 2014-05-08. PMID:23962570. |
three limbic brain regions, the prefrontal cortex (pfc), caudate putamen (cpu), and nucleus accumbens (nac), were dissected. |
2014-05-08 |
2023-08-12 |
rat |
| R M Villalba, Y Smit. Differential striatal spine pathology in Parkinson's disease and cocaine addiction: a key role of dopamine? Neuroscience. vol 251. 2014-04-23. PMID:23867772. |
in pd, nigrostriatal dopamine degeneration results in a significant loss of dendritic spines in the dorsal striatum, while rodents chronically exposed to cocaine and other psychostimulants, display an increase in the density of "thin and immature" spines in the nucleus accumbens (nac). |
2014-04-23 |
2023-08-12 |
Not clear |
| P Trifilieff, B Feng, E Urizar, V Winiger, R D Ward, K M Taylor, D Martinez, H Moore, P D Balsam, E H Simpson, J A Javitc. Increasing dopamine D2 receptor expression in the adult nucleus accumbens enhances motivation. Molecular psychiatry. vol 18. issue 9. 2014-03-25. PMID:23711983. |
in this study, we used a viral vector strategy to overexpress postsynaptic d2rs in either the nac or the dorsal striatum. |
2014-03-25 |
2023-08-12 |
Not clear |
| S D Schlussman, M Buonora, A J Brownstein, Y Zhang, A Ho, M J Kree. Regional mRNA expression of GABAergic receptor subunits in brains of C57BL/6J and 129P3/J mice: strain and heroin effects. Brain research. vol 1523. 2014-02-04. PMID:23732339. |
in this study, we examined the contribution of the gabaergic system in the cortex, nucleus accumbens (nac), caudate putamen (cpu) and the region containing the substantia nigra and ventral tegmental area (sn/vta) to heroin reward by measuring mrna levels of 7 of the most commonly expressed gaba-a receptor subunits, and both gaba-b receptor subunits, in these same mice following saline (control) or heroin administration in a cpp design. |
2014-02-04 |
2023-08-12 |
mouse |
| R A Chambers, J N McClintick, A M Sentir, S A Berg, M Runyan, K H Choi, H J Edenber. Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization. Genes, brain, and behavior. vol 12. issue 5. 2014-01-27. PMID:23682998. |
rat genome-wide microarrays containing >24 000 probesets were used to examine separate and co-occurring effects of nvhls and cocaine sensitization (15 mg/kg/day × 5 days) on gene expression within medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate-putamen (capu). |
2014-01-27 |
2023-08-12 |
rat |
| Marguerite Matthews, Corina Bondi, Gonzalo Torres, Bita Moghadda. Reduced presynaptic dopamine activity in adolescent dorsal striatum. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 7. 2014-01-24. PMID:23358239. |
we combined molecular and dynamic indices of dopamine neurotransmission to assess dopamine function in adolescent rats in two functionally distinct striatal subregions: nucleus accumbens (nac) and dorsal striatum (ds). |
2014-01-24 |
2023-08-12 |
rat |
| Mary Kay Lobo, Samir Zaman, Diane M Damez-Werno, Ja Wook Koo, Rosemary C Bagot, Jennifer A DiNieri, Alexandria Nugent, Eric Finkel, Dipesh Chaudhury, Ramesh Chandra, Efrain Riberio, Jacqui Rabkin, Ezekiell Mouzon, Roger Cachope, Joseph F Cheer, Ming-Hu Han, David M Dietz, David W Self, Yasmin L Hurd, Vincent Vialou, Eric J Nestle. ΔFosB induction in striatal medium spiny neuron subtypes in response to chronic pharmacological, emotional, and optogenetic stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 47. 2014-01-21. PMID:24259563. |
we make use of fluorescent reporter bac transgenic mice to evaluate induction of Δfosb in dopamine receptor 1 (d1) enriched and dopamine receptor 2 (d2) enriched msns in ventral striatum, nucleus accumbens (nac) shell and core, and in dorsal striatum (dstr) after chronic exposure to several drugs of abuse including cocaine, ethanol, Δ(9)-tetrahydrocannabinol, and opiates; the antipsychotic drug, haloperidol; juvenile enrichment; sucrose drinking; calorie restriction; the serotonin selective reuptake inhibitor antidepressant, fluoxetine; and social defeat stress. |
2014-01-21 |
2023-08-12 |
mouse |