| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michelle K Sequeira, Britta S Nelson, Hannah D Fulenwider, Courtney E King, Sadie E Nennig, Jennifer B Bohannon, Kejun Cheng, Kenner C Rice, Markus Heilig, Jesse R Schan. The neurokinin-1 receptor mediates escalated alcohol intake induced by multiple drinking models. Neuropharmacology. vol 137. 2019-02-20. PMID:29758386. |
escalated consumption induced by intermittent access was attenuated when the nk1r antagonist l822429 was infused directly into the dorsal striatum, but not when infused into the nac. |
2019-02-20 |
2023-08-13 |
rat |
| Yu-Hua Tian, Shi-Xun Ma, Kwang-Wook Lee, Sunmee Wee, George F Koob, Seok-Yong Lee, Choon-Gon Jan. Blockade of TRPV1 Inhibits Methamphetamine-induced Rewarding Effects. Scientific reports. vol 8. issue 1. 2018-11-27. PMID:29343767. |
recent studies have identified the distribution of trpv1 in several brain regions that are related to drug addiction, including nucleus accumbens (nac) and dorsal striatum (dst). |
2018-11-27 |
2023-08-13 |
mouse |
| Yanjiong Chen, Cuo Yang, Li Zhu, Jiaqi Li, Fanglin Guan, Teng Che. Depletion of D3 dopamine receptor affects methamphetamine-induced expression patterns of Pde4b and Atf3. Neuroscience letters. vol 665. 2018-11-13. PMID:29175029. |
here, we measured changes in pde4b and atf3 in the camp signaling pathway of dopaminergic system components, including the nucleus accumbens (nac), caudate putamen (cpu) and hippocampus (hip), in d3r knockout mice(d3r-/-) 1h and 24h after meth-induced behavioral sensitization. |
2018-11-13 |
2023-08-13 |
mouse |
| Mei Bai, Xiongzhao Zhu, Li Zhang, Yi Zhang, Liang Xue, Yuting Wang, Mingtian Zhong, Xiuwu Zhan. Divergent anomaly in mesocorticolimbic dopaminergic circuits might be associated with different depressive behaviors, an animal study. Brain and behavior. vol 7. issue 10. 2018-07-09. PMID:29075568. |
the mesocorticolimbic dopamine system, which originates from the ventral tegmental area (vta) and projects primarily to the prefrontal cortex (pfc), olfactory tubercle (ot), nucleus accumbens (nac), dorsal striatum (st), and the amygdala (amy), plays a pivotal role in determining individual motivation and sensitivity to rewards, namely, anhedonia. |
2018-07-09 |
2023-08-13 |
Not clear |
| Cristina Cadoni, Augusta Pisanu, Nicola Simola, Lucia Frau, Pier Francesca Porceddu, Silvia Corongiu, Christian Dessì, Annesha Sil, Antonio Plumitallo, Jadwiga Wardas, Gaetano Di Chiar. Widespread reduction of dopamine cell bodies and terminals in adult rats exposed to a low dose regimen of MDMA during adolescence. Neuropharmacology. vol 123. 2018-04-17. PMID:28603026. |
mdma reduced density of tyrosine hydroxylase (th) positive neurons in the ventral tegmental area and in the substantia nigra pars compacta, and immunoreactivity of th and da transporter in the nucleus accumbens (nac) shell and core, and caudate-putamen. |
2018-04-17 |
2023-08-13 |
rat |
| Xiaoqun Zhang, Ning Yao, Karima Chergu. The GABAA receptor agonist muscimol induces an age- and region-dependent form of long-term depression in the mouse striatum. Learning & memory (Cold Spring Harbor, N.Y.). vol 23. issue 9. 2018-01-19. PMID:27531838. |
several forms of long-term depression (ltd) of glutamatergic synaptic transmission have been identified in the dorsal striatum and in the nucleus accumbens (nac). |
2018-01-19 |
2023-08-13 |
mouse |
| Egemen Kaya, Oguz Gozen, Muzeyyen Ugur, Ersin O Koylu, Lutfiye Kanit, Burcu Balka. Nicotine regulates cocaine-amphetamine-Regulated Transcript (Cart) in the mesocorticolimbic system. Synapse (New York, N.Y.). vol 70. issue 7. 2017-12-22. PMID:26990424. |
cart mrna and peptide levels in medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum (dst), amygdala (amg), lateral hypothalamic area (lha), and ventral tegmental area (vta) were measured by quantitative real-time pcr (qpcr) and western blot analysis, respectively. |
2017-12-22 |
2023-08-13 |
rat |
| Lu Li, Chuchu Qiao, Gang Chen, Hongyan Qian, Ying Hou, Tao Li, Xinshe Li. Ifenprodil attenuates the acquisition and expression of methamphetamine-induced behavioral sensitization and activation of Ras-ERK1/2 cascade in the caudate putamen. Neuroscience. vol 335. 2017-12-21. PMID:27544406. |
then, using western blot, ras, perk1/2/erk1/2, and Δfosb levels in the prefrontal cortex (pfc), nucleus accumbens (nac), and caudate putamen (cpu) were detected. |
2017-12-21 |
2023-08-13 |
mouse |
| Luyi Zhou, Wei-Lun Sun, Karen Weierstall, Ana Christina Minerly, Jan Weiner, Shirzad Jenab, Vanya Quinones-Jena. Sex differences in behavioral and PKA cascade responses to repeated cocaine administration. Psychopharmacology. vol 233. issue 19-20. 2017-11-24. PMID:27553823. |
correspondent pka-associated signaling in the nucleus accumbens (nac) and caudate-putamen (cpu) was measured at each time point. |
2017-11-24 |
2023-08-13 |
rat |
| Haichen Niu, Guanqun Zhang, Haiying Li, Qiang Zhang, Tongzhou Li, Sheng Ding, Lei Wang, Zhonghai Zhang, Yuehua Qiao, Min H. Multi-system state shifts and cognitive deficits induced by chronic morphine during abstinence. Neuroscience letters. vol 640. 2017-10-24. PMID:27984200. |
our in-vivo memri data using the voxel-wise comparisons showed that the manganese-enhanced signal intensity (vmi) within morphine withdrawal groups was increased in cingulate cortex (cg), secondary motor cortex (m2), ca3 subfield of hippocampus, dorsal striatum (d-striatum), retrosplenial cortex (rs), shell subregion of nac (acbsh), core subregion of nac (acbc), central nucleus of amygdala (cec), basolateral amygdaloid nucleus (bla), central amygdaloid nucleus (cem), anterior hypothalamic area, central (ahc), ventral tegmental area (vta) and scaphoid thalamic nucleus (sc).however, decreasing of vmi was found in the ventrolateral striatum (v-striatum) and lateral posterior thalamic nucleus (lp) compared to the control group. |
2017-10-24 |
2023-08-13 |
rat |
| Yongsheng Zhu, Bo Xing, Wei Dang, Yuanyuan Ji, Peng Yan, Yunxiao Li, Xiaomeng Qiao, Jianghua La. AUTS2 in the nucleus accumbens is essential for heroin-induced behavioral sensitization. Neuroscience. vol 333. 2017-09-06. PMID:27423627. |
here, we investigated the effects of acute and chronic heroin exposure on auts2 mrna and protein expression in the nucleus accumbens (nac) and caudate-putamen (cpu) to determine whether changes in auts2 expression are associated with heroin-induced locomotor sensitization in mice. |
2017-09-06 |
2023-08-13 |
mouse |
| Julie A D Dela Cruz, Tricia Coke, Richard J Bodna. Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats. Journal of visualized experiments : JoVE. issue 114. 2017-08-14. PMID:27583636. |
thus, sugar intake elicits da release and increases c-fos-like immunoreactivity (fli) from individual vta da projection zones including the nucleus accumbens (nac), amygdala (amy) and medial prefrontal cortex (mpfc) as well as the dorsal striatum. |
2017-08-14 |
2023-08-13 |
rat |
| Julie A D Dela Cruz, Tricia Coke, Richard J Bodna. Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats. Journal of visualized experiments : JoVE. issue 114. 2017-08-14. PMID:27583636. |
one approach by which to determine whether these sites interacted as a distributed brain network in response to sugar or fat intake would be to simultaneous evaluate whether the vta and its major mesotelencephalic da projection zones (prelimbic and infralimbic mpfc, core and shell of the nac, basolateral and central-cortico-medial amy) as well as the dorsal striatum would display coordinated and simultaneous fli activation after oral, unconditioned intake of corn oil (3.5%), glucose (8%), fructose (8%) and saccharin (0.2%) solutions. |
2017-08-14 |
2023-08-13 |
rat |
| Kellie S Gross, Dieter D Brandner, Luis A Martinez, M Foster Olive, Robert L Meisel, Paul G Mermelstei. Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density. PloS one. vol 11. issue 9. 2017-08-02. PMID:27618534. |
specifically, mglur5 positive modulation decreased dendritic spine densities in the nac shell and core, but was without effect in the dorsal striatum, whereas increased spine densities in the nac were observed with mglur1a positive modulation. |
2017-08-02 |
2023-08-13 |
Not clear |
| Kymry T Jones, Catherine Woods, Juan Zhen, Tamara Antonio, Kenneth D Carr, Maarten E A Reit. Effects of diet and insulin on dopamine transporter activity and expression in rat caudate-putamen, nucleus accumbens, and midbrain. Journal of neurochemistry. vol 140. issue 5. 2017-06-23. PMID:27973691. |
in this study, we examined diet effects on expression and function of the dopamine transporter (dat) in caudate-putamen (cpu), nucleus accumbens (nac), and midbrain regions. |
2017-06-23 |
2023-08-13 |
rat |
| Junshi Wang, Ryan M Bastle, Caroline E Bass, Ronald P Hammer, Janet L Neisewander, Ella M Nikulin. Overexpression of BDNF in the ventral tegmental area enhances binge cocaine self-administration in rats exposed to repeated social defeat. Neuropharmacology. vol 109. 2017-06-19. PMID:27154426. |
vta bdnf overexpression increased Δfosb expression in the nac, but not in the dorsal striatum. |
2017-06-19 |
2023-08-13 |
rat |
| Janaine C Carvalho, Patricia C Lisboa, Elaine de Oliveira, Nayara Peixoto-Silva, Cintia R Pinheiro, Mabel C Fraga, Sylvio Claudio-Neto, Celso R Franci, Alex C Manhães, Egberto G Mour. Effects of early and late neonatal bromocriptine treatment on hypothalamic neuropeptides, dopaminergic reward system and behavior of adult rats. Neuroscience. vol 325. 2017-06-07. PMID:27038750. |
the dopamine pathway was analyzed in the ventral tegmental area (vta), nucleus accumbens (nac) and dorsal striatum (ds) at pn180. |
2017-06-07 |
2023-08-13 |
rat |
| Michael De Santis, Jiamei Lian, Xu-Feng Huang, Chao Den. Early Antipsychotic Treatment in Juvenile Rats Elicits Long-Term Alterations to the Dopamine Neurotransmitter System. International journal of molecular sciences. vol 17. issue 11. 2017-04-04. PMID:27879654. |
additionally, risperidone treatment increased d₁ receptor levels in the hippocampus of females, whilst, in males, p-th levels increased in the pfc and hippocampus, d₁ receptor expression decreased in the nac, and dat levels decreased in the caudate putamen (cpu), and elevated in the vta. |
2017-04-04 |
2023-08-13 |
rat |
| Bo Pan, Jiamei Lian, Xu-Feng Huang, Chao Den. Aripiprazole Increases the PKA Signalling and Expression of the GABAA Receptor and CREB1 in the Nucleus Accumbens of Rats. Journal of molecular neuroscience : MN. vol 59. issue 1. 2017-03-10. PMID:26894264. |
the levels of pka-cα and p-pka in the prefrontal cortex (pfc), nucleus accumbens (nac) and caudate putamen (cpu) were detected by western blots. |
2017-03-10 |
2023-08-13 |
rat |
| Morgan H James, Rikki K Quinn, Lin Kooi Ong, Emily M Levi, Doug W Smith, Phillip W Dickson, Christopher V Daya. Rapamycin reduces motivated responding for cocaine and alters GluA1 expression in the ventral but not dorsal striatum. European journal of pharmacology. vol 784. 2017-03-02. PMID:27181066. |
systemic rapamycin treatment also reduced phosphorylated p70s6k and glua1 ampars within the nac but not dorsal striatum. |
2017-03-02 |
2023-08-13 |
Not clear |