| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Götz, U Kraushaar, J Geiger, J Lübke, T Berger, P Jona. Functional properties of AMPA and NMDA receptors expressed in identified types of basal ganglia neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 1. 1997-02-04. PMID:8987749. |
we investigated the functional properties of ampars and nmdars expressed by six main types of basal ganglia neurons in acute rat brain slices (principal neurons and cholinergic interneurons of striatum, gabaergic and dopaminergic neurons of substantia nigra, globus pallidus neurons, and subthalamic nucleus neurons) using fast application of glutamate to nucleated and outside-out membrane patches. |
1997-02-04 |
2023-08-12 |
rat |
| A M Lozano, A E Lang, N Galvez-Jimenez, J Miyasaki, J Duff, W D Hutchinson, J O Dostrovsk. Effect of GPi pallidotomy on motor function in Parkinson's disease. Lancet (London, England). vol 346. issue 8987. 1995-12-15. PMID:7475819. |
the major motor disturbances in parkinson's disease are thought to be caused by overactivity of the internal segment of the globus pallidus (gpi), in large part due to excessive drive from the subthalamic nucleus. |
1995-12-15 |
2023-08-12 |
Not clear |
| K Bell, L Churchill, P W Kaliva. GABAergic projection from the ventral pallidum and globus pallidus to the subthalamic nucleus. Synapse (New York, N.Y.). vol 20. issue 1. 1995-08-31. PMID:7624824. |
gabaergic projection from the ventral pallidum and globus pallidus to the subthalamic nucleus. |
1995-08-31 |
2023-08-12 |
Not clear |
| K Bell, L Churchill, P W Kaliva. GABAergic projection from the ventral pallidum and globus pallidus to the subthalamic nucleus. Synapse (New York, N.Y.). vol 20. issue 1. 1995-08-31. PMID:7624824. |
overall the ventral pallidum contribution to the subthalamic nucleus was less gabaergic than the portion arising from the globus pallidus (35% vs. 61%, respectively). |
1995-08-31 |
2023-08-12 |
Not clear |
| E F Ball, P J Shaw, P G Ince, M Johnso. The distribution of excitatory amino acid receptors in the normal human midbrain and basal ganglia with implications for Parkinson's disease: a quantitative autoradiographic study using [3H]MK-801, [3H]glycine, [3H]CNQX and [3H]kainate. Brain research. vol 658. issue 1-2. 1995-03-02. PMID:7834343. |
in both the medial globus pallidus and subthalamic nucleus, binding sites representing nmda, ampa and kainate receptors were all present at low density. |
1995-03-02 |
2023-08-12 |
human |
| H Bergman, T Wichmann, B Karmon, M R DeLon. The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism. Journal of neurophysiology. vol 72. issue 2. 1994-12-30. PMID:7983515. |
the activity of neurons in the subthalamic nucleus (stn) and in the internal segment of the globus pallidus (gpi) was recorded before (stn, n = 220 cells; gpi, n = 175 cells) and after mptp treatment (stn, n = 326 cells; gpi, n = 154 cells). |
1994-12-30 |
2023-08-12 |
monkey |
| T Wichmann, H Bergman, M R DeLon. The primate subthalamic nucleus. III. Changes in motor behavior and neuronal activity in the internal pallidum induced by subthalamic inactivation in the MPTP model of parkinsonism. Journal of neurophysiology. vol 72. issue 2. 1994-12-30. PMID:7983516. |
the effects of reversible and irreversible pharmacological manipulations of the neuronal activity in the subthalamic nucleus (stn) on parkinsonian motor signs and neuronal activity in the internal segment of the globus pallidus (gpi) were studied in african green monkeys rendered parkinsonian by treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. |
1994-12-30 |
2023-08-12 |
monkey |
| R H Porter, J G Greene, D S Higgins, J T Greenamyr. Polysynaptic regulation of glutamate receptors and mitochondrial enzyme activities in the basal ganglia of rats with unilateral dopamine depletion. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 11 Pt 2. 1994-12-02. PMID:7965108. |
after nigrostriatal dopaminergic denervation, the output nuclei of the basal ganglia, the medial globus pallidus and substantia nigra pars reticulata (snr), become overactive, in part, because of increased activity of excitatory afferents from the subthalamic nucleus (stn). |
1994-12-02 |
2023-08-12 |
rat |
| D G Standaert, C M Testa, A B Young, J B Penne. Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat. The Journal of comparative neurology. vol 343. issue 1. 1994-08-10. PMID:8027428. |
nmdar1 subunits are expressed throughout the basal ganglia as well as in the rest of the brain; however, the alternatively spliced amino-terminal region insertion i is abundantly expressed only in the subthalamic nucleus and is not detectable in the neostriatum, globus pallidus, or substantia nigra pars compacta. |
1994-08-10 |
2023-08-12 |
rat |
| J T Greenamyre, R V Eller, Z Zhang, A Ovadia, R Kurlan, D M Gas. Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease. Annals of neurology. vol 35. issue 6. 1994-07-08. PMID:8210221. |
loss of dopaminergic innervation of the striatum results in overactivity of the glutamatergic pathways from the subthalamic nucleus to the internal segment of the globus pallidus and the substantia nigra pars reticulata, the output nuclei of the basal ganglia. |
1994-07-08 |
2023-08-12 |
rat |
| E Storey, M F Bea. Neurochemical substrates of rigidity and chorea in Huntington's disease. Brain : a journal of neurology. vol 116 ( Pt 5). 1993-12-07. PMID:7693298. |
a model of chorea based on experimental studies in primates proposes that a loss of striatal gabaergic inhibitory projections to the globus pallidus externa leads to increased activity of the inhibitory globus pallidus externa gabaergic neurons which project to the subthalamic nucleus. |
1993-12-07 |
2023-08-12 |
Not clear |
| A T Bruinvels, J M Palacios, D Hoye. Autoradiographic characterisation and localisation of 5-HT1D compared to 5-HT1B binding sites in rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 347. issue 6. 1993-09-28. PMID:8361548. |
low densities of the 5-ht1d recognition sites were found to be present in globus pallidus, ventral pallidum, caudate-putamen, subthalamic nucleus, entopeduncular nucleus, substantia nigra (reticular part), nuclei of the (normal and accessory) optic tract, different nuclei of the geniculate body and frontoparietal cortex, although higher densities of 5-ht1b sites were always observed in the same structures. |
1993-09-28 |
2023-08-12 |
rat |
| U Wüllner, E Brouillet, O Isacson, A B Young, J B Penne. Glutamate receptor binding sites in MPTP-treated mice. Experimental neurology. vol 121. issue 2. 1993-08-31. PMID:8393409. |
our data indicate that modulation of nmda and ampa binding sites in substantia nigra and globus pallidus, the major projection areas of the subthalamic nucleus, takes place only after severe impairment of the nigrostriatal system. |
1993-08-31 |
2023-08-12 |
mouse |
| T Sugimoto, K Sato, T Houtani, T Ueyama, M Iked. On the expression of Fos-like protein in the subthalamic nucleus and basal ganglia output systems following kainic acid injections into the rodent striatum. Neuroscience letters. vol 152. issue 1-2. 1993-07-19. PMID:8515876. |
in the globus pallidus, entopeduncular nucleus, substantia nigra pars reticulata, subthalamic nucleus and ventrolateral thalamic nucleus, fos was expressed in neuronal cell nuclei showing the maximal number at 4 h and disappeared within 48 h. the substantia nigra pars compacta neurons lacked prominent fos induction, suggesting that a different mechanism may operate for changes of dopamine systems. |
1993-07-19 |
2023-08-12 |
rat |
| J M Trugman, C L Jame. D1 dopamine agonist and antagonist effects on regional cerebral glucose utilization in rats with intact dopaminergic innervation. Brain research. vol 607. issue 1-2. 1993-06-03. PMID:8481802. |
systemic administration of the selective d1 antagonist, sch 23390 (0.5 mg/kg), lowered glucose utilization by 24-28% in the globus pallidus, entopeduncular nucleus, subthalamic nucleus, substantia nigra pars reticulata (snr), and motor cortex, suggesting that stimulation of the d1 receptor by endogenous dopamine contributes to basal metabolism in these regions. |
1993-06-03 |
2023-08-12 |
rat |
| J M Trugman, C L Jame. D1 dopamine agonist and antagonist effects on regional cerebral glucose utilization in rats with intact dopaminergic innervation. Brain research. vol 607. issue 1-2. 1993-06-03. PMID:8481802. |
systemic administration of amphetamine (5.0 mg/kg), a dopamine releasing agent, increased rcgu in the caudate-putamen (up 33%), globus pallidus (up 23%), subthalamic nucleus (up 46%), entopeduncular nucleus (up 78%), and snr (up 72%) and lowered rcgu in the lateral habenula (down 43%). |
1993-06-03 |
2023-08-12 |
rat |
| A Parent, L N Hazrat. Anatomical aspects of information processing in primate basal ganglia. Trends in neurosciences. vol 16. issue 3. 1993-04-20. PMID:7681234. |
emphasis is placed on the fact that the striatum and the subthalamic nucleus have multiple representations in the two major output structures of the basal ganglia, namely the internal segment of the globus pallidus and the substantia nigra pars reticulata. |
1993-04-20 |
2023-08-12 |
Not clear |
| R H Price, Z Hollingsworth, A B Young, J B Penne. Excitatory amino acid receptor regulation after subthalamic nucleus lesions in the rat. Brain research. vol 602. issue 1. 1993-04-12. PMID:8383570. |
after complete ablation of the subthalamic nucleus, we have examined the nmda, ampa, kainate and metabotropic subtypes of excitatory amino acid receptors in two major subthalamic projection areas (globus pallidus and substantia nigra pars reticulata) with quantitative autoradiography. |
1993-04-12 |
2023-08-12 |
rat |
| L N Hazrati, A Paren. Differential patterns of arborization of striatal and subthalamic fibers in the two pallidal segments in primates. Brain research. vol 598. issue 1-2. 1993-02-25. PMID:1486492. |
double-anterograde tract-tracing experiments in the squirrel monkey (saimiri sciureus) reveal that fibers from the striatum and the subthalamic nucleus converge onto the same neurons in both the external (gpe) and internal (gpi) segments of the globus pallidus. |
1993-02-25 |
2023-08-11 |
squirrel_monkey |
| M M Mesulam, D Mash, L Hersh, M Bothwell, C Geul. Cholinergic innervation of the human striatum, globus pallidus, subthalamic nucleus, substantia nigra, and red nucleus. The Journal of comparative neurology. vol 323. issue 2. 1992-11-03. PMID:1401259. |
cholinergic innervation of the human striatum, globus pallidus, subthalamic nucleus, substantia nigra, and red nucleus. |
1992-11-03 |
2023-08-11 |
human |