| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J W Geddes, D T Monaghan, C W Cotman, I T Lott, R C Kim, H C Chu. Plasticity of hippocampal circuitry in Alzheimer's disease. Science (New York, N.Y.). vol 230. issue 4730. 1985-12-27. PMID:4071042. |
a similar expansion of kainic acid receptor distribution was observed in hippocampal samples obtained postmortem from patients with alzheimer's disease. |
1985-12-27 |
2023-08-11 |
human |
| D M Mann, P O Yates, B Marcyniu. Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age. Journal of the neurological sciences. vol 69. issue 3. 1985-10-07. PMID:3162000. |
some morphometric observations on the cerebral cortex and hippocampus in presenile alzheimer's disease, senile dementia of alzheimer type and down's syndrome in middle age. |
1985-10-07 |
2023-08-11 |
Not clear |
| D M Mann, P O Yates, B Marcyniu. Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age. Journal of the neurological sciences. vol 69. issue 3. 1985-10-07. PMID:3162000. |
the frequency of senile plaques and neurofibrillary tangles and the number of pyramidal neurones and the volume of their nucleolus were measured in temporal cortex (middle temporal gyrus) and hippocampus (area h1) of 32 patients with alzheimer's disease. |
1985-10-07 |
2023-08-11 |
Not clear |
| D M Mann, P O Yates, B Marcyniu. Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age. Journal of the neurological sciences. vol 69. issue 3. 1985-10-07. PMID:3162000. |
the number of nerve cells and the volume of their nucleolus were less (when compared with age-matched control patients) in both temporal cortex and hippocampus, in the 6 middle aged patients with down's syndrome, and match the corresponding values seen in 8 patients of similar age with alzheimer's disease. |
1985-10-07 |
2023-08-11 |
Not clear |
| J O Rinne, K Laakso, P Lönnberg, P Mölsä, L Paljärvi, J K Rinne, E Säkö, U K Rinn. Brain muscarinic receptors in senile dementia. Brain research. vol 336. issue 1. 1985-08-20. PMID:4005573. |
the binding of [3h]qnb was significantly decreased in the hippocampus, amygdala and nucleus accumbens in patients with alzheimer's disease (ad) and with combined type of dementia (cd), whereas in patients with multi-infarct dementia (mid) the binding was not significantly decreased in the limbic areas but only in the caudate nucleus. |
1985-08-20 |
2023-08-11 |
Not clear |
| B Dubois, J J Hauw, M Ruberg, M Serdaru, F Javoy-Agid, Y Agi. [Dementia and Parkinson's disease: biochemical and anatomo-clinical correlation]. Revue neurologique. vol 141. issue 3. 1985-07-19. PMID:4001706. |
thirteen of the parkinsonian patients showed signs of intellectual decline (moderate in 8, severe in 5) and neuropathological examination of the cortex revealed in 10 cases large number of alzheimer type senile changes extending beyond the hippocampus. |
1985-07-19 |
2023-08-11 |
human |
| P Nyberg, R Adolfsson, J A Hardy, A Nordberg, P Wester, B Winbla. Catecholamine topochemistry in human basal ganglia. Comparison between normal and Alzheimer brains. Brain research. vol 333. issue 1. 1985-07-02. PMID:3995281. |
analysis of catecholamine levels in postmortem human control and alzheimer brains revealed lower mean concentrations of noradrenaline, but not dopamine, in nucleus caudatus, putamen and globus pallidus, but not in hippocampus, of the alzheimer brains. |
1985-07-02 |
2023-08-11 |
human |
| S L Marklund, R Adolfsson, C G Gottfries, B Winbla. Superoxide dismutase isoenzymes in normal brains and in brains from patients with dementia of Alzheimer type. Journal of the neurological sciences. vol 67. issue 3. 1985-05-29. PMID:3989575. |
cuzn superoxide dismutase and mn superoxide dismutase were analysed in hypothalamus, nucleus caudatus, hippocampus and cortex gyrus cinguli from 14 patients with dementia of alzheimer type and from 16 controls. |
1985-05-29 |
2023-08-11 |
Not clear |
| L Cartier, S Gálvez, D C Gajduse. Familial clustering of the ataxic form of Creutzfeldt-Jakob disease with Hirano bodies. Journal of neurology, neurosurgery, and psychiatry. vol 48. issue 3. 1985-05-08. PMID:2984334. |
pathologically, the marked hippocampal involvement rarely seen in typical transmissible creutzfeldt-jakob disease and the finding of hirano bodies in the ammon's horn without specific alzheimer's senile changes are noteworthy features. |
1985-05-08 |
2023-08-11 |
Not clear |
| T Arendt, V Bigl, A Tennstedt, A Arend. Neuronal loss in different parts of the nucleus basalis is related to neuritic plaque formation in cortical target areas in Alzheimer's disease. Neuroscience. vol 14. issue 1. 1985-04-10. PMID:3974875. |
in order to substantiate the hypothesis of a cholinergic pathogenesis of neuritic plaques in alzheimer's disease the relationship between the loss of cholinergic neurons in six subdivisions of the nucleus basalis of meynert and density of neuritic plaques in five neocortical target areas and hippocampus was studied in five cases with alzheimer's disease. |
1985-04-10 |
2023-08-11 |
Not clear |
| D Dawbarn, P C Emso. Neuropeptide Y-like immunoreactivity in neuritic plaques of Alzheimer's disease. Biochemical and biophysical research communications. vol 126. issue 1. 1985-03-20. PMID:3838246. |
alzheimer's disease, a form of senile dementia, is characterized by the presence of neuritic plaques and neurofibrillary tangles throughout the cortex and hippocampus. |
1985-03-20 |
2023-08-11 |
Not clear |
| H P Schmitt, W Emser, C Heime. Familial occurrence of amyotrophic lateral sclerosis, parkinsonism, and dementia. Annals of neurology. vol 16. issue 6. 1985-03-15. PMID:6524873. |
postmortem examination revealed alzheimer's neurofibrillary tangles in the substantia nigra, innominata, locus ceruleus, parahippocampal gyrus, and less frequently in the hippocampus and the cerebral cortex. |
1985-03-15 |
2023-08-12 |
Not clear |
| S Jenni-Eiermann, H P von Hahn, C G Honegger, J Ulric. Studies on neurotransmitter binding in senile dementia. Comparison of Alzheimer's and mixed vascular-Alzheimer's dementias. Gerontology. vol 30. issue 6. 1985-03-11. PMID:6151534. |
binding of 3h-labeled agonists and antagonists to muscarinic-cholinergic, alpha- and beta-adrenergic, dopaminergic, serotoninergic, and opiate receptors was studied in four regions of the neocortex and in hippocampus, thalamus, putamen, and caudatus in autoptic material from patients with senile dementia of alzheimer type and of mixed vascular-alzheimer pathogenesis. |
1985-03-11 |
2023-08-12 |
Not clear |
| D Collerton, A Fairbair. Alzheimer's disease and the hippocampus. Lancet (London, England). vol 1. issue 8423. 1985-02-27. PMID:2857344. |
alzheimer's disease and the hippocampus. |
1985-02-27 |
2023-08-11 |
Not clear |
| N W Pedigo, L D Minor, T N Krumre. Cholinergic drug effects and brain muscarinic receptor binding in aged rats. Neurobiology of aging. vol 5. issue 3. 1985-02-21. PMID:6514108. |
cholinergic neurotransmission in cerebral cortex and hippocampus is also severely impaired in a major age-related neurological disorder, alzheimer's disease. |
1985-02-21 |
2023-08-12 |
rat |
| J R Scott, H Frase. Degenerative hippocampal pathology in mice infected with scrapie. Acta neuropathologica. vol 65. issue 1. 1985-02-19. PMID:6542738. |
scrapie-induced hippocampal sclerosis provides an experimental system for investigating the basis for similar lesions, which occur in a variety of conditions, such as alzheimer's disease and epilepsy. |
1985-02-19 |
2023-08-12 |
mouse |
| M J Ball, M Fisman, V Hachinski, W Blume, A Fox, V A Kral, A J Kirshen, H Fox, H Merske. A new definition of Alzheimer's disease: a hippocampal dementia. Lancet (London, England). vol 1. issue 8419. 1985-01-31. PMID:2856948. |
a new definition of alzheimer's disease: a hippocampal dementia. |
1985-01-31 |
2023-08-11 |
Not clear |
| D M Jacobowitz, W E Heydor. Two-dimensional gel electrophoresis used in neurobiological studies of proteins in discrete areas of the rat brain. Clinical chemistry. vol 30. issue 12 Pt 1. 1985-01-17. PMID:6499172. |
finally, we developed a possible animal model for studying proteins related to alzheimer's disease by depleting the cholinergic innervation to the cortex and the hippocampus. |
1985-01-17 |
2023-08-12 |
rat |
| E Perdahl, R Adolfsson, I Alafuzoff, K A Albert, E J Nestler, P Greengard, B Winbla. Synapsin I (protein I) in different brain regions in senile dementia of Alzheimer type and in multi-infarct dementia. Journal of neural transmission. vol 60. issue 2. 1984-12-12. PMID:6436437. |
synapsin i (protein i), a neuron-specific phosphoprotein enriched in presynaptic nerve terminals, has been used as a quantitative marker for the density of nerve terminals in five brain regions (caudate nucleus, cingulate gyrus, hippocampus, mesencephalon and putamen) from patients who had suffered from alzheimer disease/senile dementia of alzheimer type (ad/sdat), from patients with multi-infarct dementia (mid), and from age-matched controls. |
1984-12-12 |
2023-08-12 |
Not clear |
| D G Brownstein, E A Johnson, A L Smit. Spontaneous Reye's-like syndrome in BALB/cByJ mice. Laboratory investigation; a journal of technical methods and pathology. vol 51. issue 4. 1984-11-13. PMID:6482384. |
necropsy findings included swollen, diffusely pale yellow livers with panlobular microvesicular fatty change, pale renal cortices with epithelial fat droplets of the proximal convoluted tubules, and alzheimer type ii astrocytosis of the neocortex, corpus striatum, hippocampus, and thalamus. |
1984-11-13 |
2023-08-12 |
mouse |