All Relations between hippocampus and fear conditioning paradigm

Publication Sentence Publish Date Extraction Date Species
Ugwechi Amadi, Seh Hong Lim, Elizabeth Liu, Michael V Baratta, Ki A Goosen. Hippocampal Processing of Ambiguity Enhances Fear Memory. Psychological science. vol 28. issue 2. 2018-01-04. PMID:28182526. during fear conditioning with unpredictably timed aversive events, pharmacological inactivation of the dorsal hippocampus or optogenetic silencing of cornu ammonis 1 cells during aversive negative prediction errors prevented this enhancement of fear without affecting fear learning for predictable events. 2018-01-04 2023-08-13 Not clear
Ugwechi Amadi, Seh Hong Lim, Elizabeth Liu, Michael V Baratta, Ki A Goosen. Hippocampal Processing of Ambiguity Enhances Fear Memory. Psychological science. vol 28. issue 2. 2018-01-04. PMID:28182526. dorsal hippocampal inactivation also prevented ambiguity-related enhancement of fear during auditory fear conditioning under a partial-reinforcement schedule. 2018-01-04 2023-08-13 Not clear
Syed Ahsan Raza, Anne Albrecht, Gürsel Çalışkan, Bettina Müller, Yunus Emre Demiray, Susann Ludewig, Susanne Meis, Nicolai Faber, Roland Hartig, Burkhart Schraven, Volkmar Lessmann, Herbert Schwegler, Oliver Stor. HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience. Nature communications. vol 8. issue 1. 2017-12-26. PMID:28775269. with pharmacogenetic inhibition we here demonstrate that hilar perforant path-associated (hipp) cells of the dentate gyrus mediate the devaluation of background context memory during pavlovian fear conditioning. 2017-12-26 2023-08-13 Not clear
S-W Yoo, M Bae, L B Tovar-Y-Romo, N J Haughe. Hippocampal encoding of interoceptive context during fear conditioning. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28045462. hippocampal encoding of interoceptive context during fear conditioning. 2017-11-16 2023-08-13 Not clear
Alexander J McDonald, David D Mot. Functional neuroanatomy of amygdalohippocampal interconnections and their role in learning and memory. Journal of neuroscience research. vol 95. issue 3. 2017-11-13. PMID:26876924. whereas neuroanatomical studies indicate that the amygdala only has direct interconnections with the ventral hippocampal region, electrophysiological studies and behavioral studies investigating fear conditioning and extinction, as well as amygdalar modulation of hippocampal-dependent mnemonic functions, suggest that the amygdala interacts with dorsal hippocampal regions via relays in the parahippocampal cortices. 2017-11-13 2023-08-13 Not clear
A Hermann, R Stark, M R Milad, C J Mer. Renewal of conditioned fear in a novel context is associated with hippocampal activation and connectivity. Social cognitive and affective neuroscience. vol 11. issue 9. 2017-10-23. PMID:27053767. renewal of conditioned fear in a novel context is associated with hippocampal activation and connectivity. 2017-10-23 2023-08-13 Not clear
A Hermann, R Stark, M R Milad, C J Mer. Renewal of conditioned fear in a novel context is associated with hippocampal activation and connectivity. Social cognitive and affective neuroscience. vol 11. issue 9. 2017-10-23. PMID:27053767. findings in rodents underpin the hippocampus' role in conditioned fear renewal in novel contexts, but it has yet to be investigated in humans. 2017-10-23 2023-08-13 Not clear
A Hermann, R Stark, M R Milad, C J Mer. Renewal of conditioned fear in a novel context is associated with hippocampal activation and connectivity. Social cognitive and affective neuroscience. vol 11. issue 9. 2017-10-23. PMID:27053767. these results outline the pivotal role of the hippocampus and its connectivity in conditioned fear renewal in a novel context in humans and might have important implications for exposure therapy in anxiety disorders. 2017-10-23 2023-08-13 Not clear
Ye Ma, Chan Chen, Shu Zhang, Qiao Wang, Hai Chen, Yuanlin Dong, Zheng Zhang, Yan Li, Zhendong Niu, Tao Zhu, Hai Yu, Bin Li. RNase alleviates neurological dysfunction in mice undergoing cardiac arrest and cardiopulmonary resuscitation. Oncotarget. vol 8. issue 32. 2017-09-25. PMID:28881795. we found that rnase administration could: 1) improve neurologic score on day 1 and day 3 after ca/cpr performance; 2) improve memory and learning ability on day 3 after training in contextual fear-conditioning test; 3) reduce extracellular rna (exrna) level in plasma and hippocampus tissue, and hippocampal cytokines mrna production on day 3 after ca/cpr procedure; 4) attenuate autophagy levels in hippocampus tissue on day 3 after ca/cpr procedure. 2017-09-25 2023-08-13 mouse
Woong Bin Kim, Jun-Hyeong Ch. Synaptic Targeting of Double-Projecting Ventral CA1 Hippocampal Neurons to the Medial Prefrontal Cortex and Basal Amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 19. 2017-08-18. PMID:28385873. previous studies have suggested that a ca1 neuronal population in the ventral hippocampus (vh) projects to both the mpfc and amygdala and is recruited in context-dependent control of conditioned fear. 2017-08-18 2023-08-13 mouse
Xu Jing, Wen-Hai Sui, Shuai Wang, Xu-Feng Xu, Rong-Rong Yuan, Xiao-Rong Chen, Hui-Xian Ma, Ying-Xiao Zhu, Jin-Kai Sun, Fan Yi, Zhe-Yu Chen, Yue Wan. HDAC7 Ubiquitination by the E3 Ligase CBX4 Is Involved in Contextual Fear Conditioning Memory Formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 14. 2017-07-27. PMID:28283560. in this study, we demonstrated that hdac7, within the dorsal hippocampus of c57bl6j mice, had a late and persistent decrease after contextual fear conditioning (cfc) training (4-24 h), which was involved in long-term cfc memory formation. 2017-07-27 2023-08-13 mouse
Jonathan J Simone, Cheryl M McCormic. Intracellular signalling and plasma hormone profiles associated with the expression of unconditioned and conditioned fear and anxiety in female rats. Physiology & behavior. vol 169. 2017-06-28. PMID:27939364. here, we investigated whether unconditioned and conditioned fear are associated with distinct patterns of expression of extracellular signal-regulated kinase-1 and -2 (erk1/2), protein kinase b (akt), and calcineurin (can) (proteins that are key regulators of the expression of and/or memory processes of fear and anxiety) in the dorsal and ventral hippocampus, medial prefrontal cortex, and amygdala (important regions in neural fear circuitry) of adult female rats, and used a multivariate approach to find patterns of signalling that might discriminate between the different states of fear. 2017-06-28 2023-08-13 rat
Laura E Villasana, Sydney Weber, Tunde Akinyeke, Jacob Rabe. Genotype differences in anxiety and fear learning and memory of WT and ApoE4 mice associated with enhanced generation of hippocampal reactive oxygen species. Journal of neurochemistry. vol 138. issue 6. 2017-06-13. PMID:27412623. the greater generation of ros in the hippocampus of e4 than wt mice might contribute to their higher anxiety levels and enhanced fear conditioning. 2017-06-13 2023-08-13 mouse
Manuel Kuhn, Jan Haaker, Evelyn Glotzbach-Schoon, Dirk Schümann, Marta Andreatta, Marie-Luise Mechias, Karolina Raczka, Nina Gartmann, Christian Büchel, Andreas Mühlberger, Paul Pauli, Andreas Reif, Raffael Kalisch, Tina B Lonsdor. Converging evidence for an impact of a functional NOS gene variation on anxiety-related processes. Social cognitive and affective neuroscience. vol 11. issue 5. 2017-04-28. PMID:26746182. while autonomous measures (fear-potentiated startle) provided only suggestive evidence for a modulatory role of nos1-ex1f-vntr on (contextual) fear conditioning processes, neural activation at the amygdala/anterior hippocampus junction was significantly increased in short-allele carriers during context conditioning. 2017-04-28 2023-08-13 human
Lizeth K Pedraza, Rodrigo O Sierra, Ana P Crestani, Jorge A Quillfeldt, Lucas de Oliveira Alvare. Sequential learning during contextual fear conditioning guides the rate of systems consolidation: Implications for consolidation of multiple memory traces. Hippocampus. vol 27. issue 5. 2017-04-25. PMID:28100032. here, we studied the influence of sequential learning in contextual fear conditioning (cfc) with different training intensities in the time-course of hippocampal dependency and contextual specificity. 2017-04-25 2023-08-13 Not clear
Pascal Ravassard, Al Mahdy Hamieh, Mickaël Antoine Joseph, Nicolas Fraize, Paul-Antoine Libourel, Léa Lebarillier, Sébastien Arthaud, Claire Meissirel, Monique Touret, Gaël Malleret, Paul-Antoine Sali. REM Sleep-Dependent Bidirectional Regulation of Hippocampal-Based Emotional Memory and LTP. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 4. 2016-12-13. PMID:25585510. our results indicate that 4 h rsd impaired consolidation of contextual fear conditioning (cfc) and induction of long-term potentiation (ltp), while decreasing density of egr1/zif268-expressing neurons in the ca1 region of the dorsal hippocampus. 2016-12-13 2023-08-13 rat
Alex L Deal, Kristen J Erickson, Stephanie I Shiers, Michael A Burma. Limbic system development underlies the emergence of classical fear conditioning during the third and fourth weeks of life in the rat. Behavioral neuroscience. vol 130. issue 2. 2016-12-13. PMID:26820587. the current experiments examine the ontogeny of fear conditioning and relate it to neuronal activation assessed through immediate early gene (ieg) expression in the amygdala, hippocampus, perirhinal cortex, and hypothalamus of periweanling rats. 2016-12-13 2023-08-13 human
Anna Tishkina, Mikhail Stepanichev, Irina Kudryashova, Sofia Freiman, Mikhail Onufriev, Natalia Lazareva, Natalia Gulyaev. Neonatal proinflammatory challenge in male Wistar rats: Effects on behavior, synaptic plasticity, and adrenocortical stress response. Behavioural brain research. vol 304. 2016-12-13. PMID:26851557. effects of neonatal proinflammatory stress (nps) on the development of anxiety and depressive-like behavior, stress responsiveness, hippocampal plasticity and conditioned fear response were studied in adolescent and adult male wistar rats. 2016-12-13 2023-08-13 rat
Edgardo Castro-Pérez, Emilio Soto-Soto, Marizabeth Pérez-Carambot, Dawling Dionisio-Santos, Kristian Saied-Santiago, Humberto G Ortiz-Zuazaga, Sandra Peña de Orti. Identification and Characterization of the V(D)J Recombination Activating Gene 1 in Long-Term Memory of Context Fear Conditioning. Neural plasticity. vol 2016. 2016-11-04. PMID:26843989. here we report data using c57bl/6 mice showing that the v(d)j recombination-activating gene 1 (rag1), which encodes a factor that introduces dsbs in immunoglobulin and t-cell receptor genes, is induced in the amygdala, but not in the hippocampus, after context fear conditioning. 2016-11-04 2023-08-13 mouse
Masaki Kikugawa, Hiroyasu Tsutsuki, Tomoaki Ida, Hidemitsu Nakajima, Hideshi Ihara, Tatsuji Sakamot. Water-soluble ferulic acid derivatives improve amyloid-β-induced neuronal cell death and dysmnesia through inhibition of amyloid-β aggregation. Bioscience, biotechnology, and biochemistry. vol 80. issue 3. 2016-10-21. PMID:26540606. in in vivo experiments, oral administration of water-soluble fa derivatives to mice improved aβ-induced dysmnesia assessed by contextual fear conditioning test and protected hippocampal neurons against aβ-induced neurotoxicity. 2016-10-21 2023-08-13 mouse