| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sahifeh Kazemi, Samaneh Safari, Somayeh Komaki, Seyed Asaad Karimi, Zoleikha Golipoor, Alireza Komak. The effects of carvacrol and p-cymene on Aβ CNS neuroscience & therapeutics. 2023-09-20. PMID:37727020. |
considering the beneficial effects of carvacrol (car) and p-cymene against ad, their effect was assessed on in vivo hippocampal ltp in the perforant pathway (pp)-dentate gyrus (dg) pathway in an aβ |
2023-09-20 |
2023-10-07 |
Not clear |
| Christos Panagiotis Lisgaras, Helen E Scharfma. Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by medial septum. Neurobiology of disease. 2023-09-15. PMID:37714307. |
because hippocampus and cortex exhibit altered excitability in ad models, we asked which areas dominate the activity during iis along the cortical-ca1-dentate gyrus (dg) dorso-ventral axis. |
2023-09-15 |
2023-10-07 |
mouse |
| Mingxie Ni, Meng Zheng, Bingran Chen, Xu Lu, Hui Zhao, Tao Zhu, Li Cheng, Han Han, Ting Ye, Huijun Liu, Ying Ye, Chao Huang, Xiaomei Yua. Microglial stimulation triggered by intranasal lipopolysaccharide administration produces antidepressant-like effect through ERK1/2-mediated BDNF synthesis in the hippocampus. Neuropharmacology. 2023-09-07. PMID:37678448. |
we recently reported that reversing the chronic stress-induced decline of microglia in the dentate gyrus (dg) of the hippocampus by intraperitoneal injection of a low dose of lipopolysaccharide (lps) ameliorated depression-like behavior in chronically stressed mice. |
2023-09-07 |
2023-10-07 |
mouse |
| Sumire Matsuura, Yuki Nishimoto, Akane Endo, Hirono Shiraki, Kanzo Suzuki, Eri Segi-Nishid. Hippocampal Inflammation and Gene Expression Changes in Peripheral Lipopolysaccharide Challenged Mice Showing Sickness and Anxiety-Like Behaviors. Biological & pharmaceutical bulletin. vol 46. issue 9. 2023-09-04. PMID:37661396. |
the aim of this study was to clarify temporal changes in the neuroinflammatory responses in the hippocampus and the response of dentate gyrus (dg) neurons using peripheral lipopolysaccharide (lps)-challenged mice. |
2023-09-04 |
2023-09-07 |
mouse |
| Satoshi Deyam. [Elucidation of the Mechanisms Underlying the Rapid Antidepressant Actions of Ketamine and Search for Possible Candidates for Novel Rapid-acting Antidepressants]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 143. issue 9. 2023-09-04. PMID:37661437. |
moreover, the intranasal administration of rve1 elicits rapid antidepressant-like effects through the release of bdnf and vegf in the mpfc and hippocampal dentate gyrus (dg), as well as mtorc1 activation in the mpfc, albeit not in the dg. |
2023-09-04 |
2023-09-07 |
human |
| Ruiyi Chen, Yash S Vakilna, Samuel Brandon Lassers, William C Tang, Gregory J Brewe. Hippocampal network axons respond to patterned theta burst stimulation with lower activity of initially higher spike train similarity from EC to DG and later similarity of axons from CA1 to EC. Journal of neural engineering. 2023-09-04. PMID:37666242. |
hippocampal network axons respond to patterned theta burst stimulation with lower activity of initially higher spike train similarity from ec to dg and later similarity of axons from ca1 to ec. |
2023-09-04 |
2023-09-07 |
Not clear |
| Seyed Mehdi Vatandoust, Javad Mahmoudi, Shahrbanoo Oryan, Fereshteh Farajdokht, Saeed Sadigh-Eteghad, Siamak Sandoghchian Shotorbani, Huaxi Xu, Delaram Eslimi Esfahan. Sericin improves memory and sociability impairments evoked by transient global cerebral ischemia through suppression of hippocampal oxidative stress, inflammation, and apoptosis. The Chinese journal of physiology. vol 66. issue 4. 2023-08-28. PMID:37635480. |
notably, ser decreased neuronal apoptotic cell death in the hippocampal dentate gyrus (dg) region, accompanied by suppression of neuroinflammation, downregulation of pro-apoptotic proteins (caspase-9, caspases-3, and bax), and upregulation of anti-apoptotic protein, bcl-2. |
2023-08-28 |
2023-09-07 |
mouse |
| Grace Minogue, Allegra Kawles, Antonia Zouridakis, Rachel Keszycki, Alyssa Macomber, Vivienne Lubbat, Nathan Gill, Qinwen Mao, Margaret E Flanagan, Hui Zhang, Rudolph Castellani, Eileen H Bigio, M-Marsel Mesulam, Changiz Geula, Tamar Gefe. Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with TDP-43. Annals of neurology. 2023-08-18. PMID:37592884. |
here, we investigated neuronal integrity and pathologic burden of tdp-43 and tau along the well-charted trisynaptic hippocampal circuit [dentate gyrus (dg), ca3, and ca1] in participants with amnestic dementia due to ad/tdp, amnestic dementia due to ad alone, or non-amnestic dementia due to tdp-43 proteinopathy associated with frontotemporal lobar degeneration (ftld-tdp). |
2023-08-18 |
2023-09-07 |
human |
| Deep R Sharma, Bokun Cheng, Rauhin Sahu, Xusheng Zhang, Rana Mehdizadeh, Divya Singh, Dumitru Iacobas, Praveen Ballab. Oestrogen treatment restores dentate gyrus development in premature newborns by IGF1 regulation. Journal of cellular and molecular medicine. 2023-08-18. PMID:37594177. |
prematurity diminishes neurogenesis and synaptogenesis in the hippocampal dentate gyrus (dg). |
2023-08-18 |
2023-09-07 |
rabbit |
| Nanami Kasakura, Yuka Murata, Asuka Shindo, Shiho Kitaoka, Tomoyuki Furuyashiki, Kanzo Suzuki, Eri Segi-Nishid. Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process. Frontiers in neuroscience. vol 17. 2023-08-14. PMID:37575306. |
the dentate gyrus (dg) of the hippocampus regulates stress-related emotional behaviors and ensures neurogenesis throughout life. |
2023-08-14 |
2023-08-16 |
Not clear |
| Nanami Kasakura, Yuka Murata, Asuka Shindo, Shiho Kitaoka, Tomoyuki Furuyashiki, Kanzo Suzuki, Eri Segi-Nishid. Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process. Frontiers in neuroscience. vol 17. 2023-08-14. PMID:37575306. |
nt-3 is expressed in the adult dg of the hippocampus; several chronic stress conditions enhance nt-3 expression in rodents. |
2023-08-14 |
2023-08-16 |
Not clear |
| Nanami Kasakura, Yuka Murata, Asuka Shindo, Shiho Kitaoka, Tomoyuki Furuyashiki, Kanzo Suzuki, Eri Segi-Nishid. Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process. Frontiers in neuroscience. vol 17. 2023-08-14. PMID:37575306. |
to directly investigate the impact of nt-3 on dg function, nt-3 was overexpressed in the hippocampal ventral dg by an adeno-associated virus carrying nt-3 (aav-nt-3). |
2023-08-14 |
2023-08-16 |
Not clear |
| Xue Wang, Ya-Jin Shi, Ting-Yuan Niu, Ting-Ting Chen, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Neuroprotective effect of 20 (S) - Protopanaxadiol (PPD) attenuates NLRP3 inflammasome-mediated microglial pyroptosis in vascular dementia rats. Neuroscience letters. 2023-08-14. PMID:37579868. |
ppd significantly reduced the cerebral infarction area and the activation of microglia in the cortex and hippocampal dg, ca1, and ca3 area. |
2023-08-14 |
2023-09-07 |
rat |
| Xue Wang, Ya-Jin Shi, Ting-Yuan Niu, Ting-Ting Chen, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Neuroprotective effect of 20 (S) - Protopanaxadiol (PPD) attenuates NLRP3 inflammasome-mediated microglial pyroptosis in vascular dementia rats. Neuroscience letters. 2023-08-14. PMID:37579868. |
ppd also significantly alleviated the neurotoxicity by decreasing the aβ and p-tau in hippocampal dg, ca1, and ca3 areas. |
2023-08-14 |
2023-09-07 |
rat |
| Yifan Wang, Qin Hong, Yueyue Xia, Zhao Zhang, Bo We. The Lysine Demethylase KDM7A Regulates Immediate Early Genes in Neurons. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-08-11. PMID:37565374. |
furthermore, in vivo knockdown of kdm7a in dentate gyrus (dg) neuron of mice hippocampus, via adeno-associated virus (aav)-based stereotaxic microinjection, led to a significant decrease of the expression of c-fos, a marker of neuron activity. |
2023-08-11 |
2023-08-16 |
mouse |
| Sophia Vinci-Booher, Margaret L Schlichting, Alison R Preston, Franco Pestill. Development of human hippocampal subfield microstructure and relation to associative inference. Cerebral cortex (New York, N.Y. : 1991). 2023-08-09. PMID:37557916. |
while the subiculum (sub) displayed a linear relationship with age, the dentate gyrus (dg), cornu ammonis field 1 (ca1), and cornu ammonis subfields 2 and 3 (combined; ca2/3) displayed nonlinear trajectories that interacted with sex in ca2/3. |
2023-08-09 |
2023-08-16 |
human |
| Yu-Wen Hung, Guan-Ling Lu, Hwei-Hsien Chen, Hsiu-Hui Tung, Sheau-Ling Le. Gliptins normalize posttraumatic hippocampal neurogenesis and restore cognitive function after controlled cortical impact on sensorimotor cortex. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-08-06. PMID:37544280. |
adult neurogenesis in the hippocampal dentate gyrus (dg) serves critical functions in cognition but can be disrupted by brain injury and insult in serval forms. |
2023-08-06 |
2023-08-14 |
mouse |
| Yu-Wen Hung, Guan-Ling Lu, Hwei-Hsien Chen, Hsiu-Hui Tung, Sheau-Ling Le. Gliptins normalize posttraumatic hippocampal neurogenesis and restore cognitive function after controlled cortical impact on sensorimotor cortex. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-08-06. PMID:37544280. |
dpp-4 inhibitors prevent astrocyte reactivation, normalize the posttraumatic hippocampal neurogenesis and help to maintain normal electrophysiology in the dg with positive behavioral effect in a mouse model. |
2023-08-06 |
2023-08-14 |
mouse |
| Pei-Pei Liu, Shi-Ping Lu, Xiao Li, Gang-Bin Tang, Xiao Liu, Shang-Kun Dai, Lin-Fei Jiao, Xi-Wen Lin, Xing-Guo Li, Baoyang Hu, Jianwei Jiao, Zhao-Qian Teng, Chun-Sheng Han, Chang-Mei Li. Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus. Cell death and differentiation. 2023-08-05. PMID:37543710. |
disruption of arid1a in mouse forebrain significantly decreases neural stem/progenitor cells (nspcs) proliferation and differentiation to neurons within the dentate gyrus (dg), increasing perinatal and postnatal apoptosis, leading to reduced hippocampus size. |
2023-08-05 |
2023-08-14 |
mouse |
| Joshua D Rieskamp, Ileanexis Rosado-Burgos, Jacob E Christofi, Eliza Ansar, Dalia Einstein, Ashley E Walters, Valentina Valentini, John P Bruno, Elizabeth D Kirb. Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal. iScience. vol 26. issue 7. 2023-08-03. PMID:37534178. |
within the adult mammalian dentate gyrus (dg) of the hippocampus, glutamate stimulates neural stem cell (nsc) self-renewing proliferation, providing a link between adult neurogenesis and local circuit activity. |
2023-08-03 |
2023-08-14 |
Not clear |