| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ernest W Wang, Guangwei Du, Mechelle M Lewis, Eun-Young Lee, Sol De Jesus, Sangam Kanekar, Lan Kong, Xuemei Huan. Multimodal MRI evaluation of parkinsonian limbic pathologies. Neurobiology of aging. vol 76. 2019-12-06. PMID:30739076. |
mean diffusivity (md), fractional anisotropy, transverse relaxation rate (r2*), quantitative susceptibility mapping, and volume measurements were obtained from the amygdala, hippocampus, and nucleus accumbens (nac) to examine differences between groups and to test for associations with clinical scores. |
2019-12-06 |
2023-08-13 |
human |
| Ernest W Wang, Guangwei Du, Mechelle M Lewis, Eun-Young Lee, Sol De Jesus, Sangam Kanekar, Lan Kong, Xuemei Huan. Multimodal MRI evaluation of parkinsonian limbic pathologies. Neurobiology of aging. vol 76. 2019-12-06. PMID:30739076. |
compared with controls, parkinson's disease subjects had lower nac volume; multiple system atrophy parkinsonian subtype subjects had higher nac transverse relaxation rate; and progressive supranuclear palsy subjects had higher amygdala and hippocampus md and lower hippocampus fractional anisotropy (p's ≤ 0.008). |
2019-12-06 |
2023-08-13 |
human |
| Samantha L Scudder, Corey Baimel, Emma E Macdonald, Adam G Carte. Hippocampal-Evoked Feedforward Inhibition in the Nucleus Accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 42. 2019-10-10. PMID:30185462. |
here, we use slice electrophysiology and optogenetics to study ventral hippocampal (vhpc)-evoked feedforward inhibition in the nac of male and female mice. |
2019-10-10 |
2023-08-13 |
mouse |
| Stephanie M Perez, Daniel J Lodg. Convergent Inputs from the Hippocampus and Thalamus to the Nucleus Accumbens Regulate Dopamine Neuron Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 50. 2019-10-09. PMID:30355626. |
the pathway by which the ventral hippocampus (vhipp) regulates dopamine neuron activity has been demonstrated previously and involves a glutamatergic projection to the nucleus accumbens (nac). |
2019-10-09 |
2023-08-13 |
rat |
| Stephanie M Perez, Daniel J Lodg. Convergent Inputs from the Hippocampus and Thalamus to the Nucleus Accumbens Regulate Dopamine Neuron Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 50. 2019-10-09. PMID:30355626. |
although projections from the hippocampus do express vglut2, inputs from the thalamus are more likely to account for this alteration; however, the role of thalamic inputs to the nac in the regulation of dopamine neuron activity has not been elucidated. |
2019-10-09 |
2023-08-13 |
rat |
| Margaret A Broadwater, Sung-Ho Lee, Yang Yu, Hongtu Zhu, Fulton T Crews, Donita L Robinson, Yen-Yu Ian Shi. Adolescent alcohol exposure decreases frontostriatal resting-state functional connectivity in adulthood. Addiction biology. vol 23. issue 2. 2019-09-17. PMID:28691248. |
frontolimbic network regions-of-interest for data analysis included pfc [prelimbic (prl), infralimbic (il), and orbitofrontal cortex (ofc) portions], nucleus accumbens (nac), caudate putamen (cpu), dorsal hippocampus, ventral tegmental area, amygdala, and somatosensory forelimb used as a control region. |
2019-09-17 |
2023-08-13 |
rat |
| Rutuja Yawalkar, Harish Changotra, Girdhari Lal Gupt. Protective influences of N-acetylcysteine against alcohol abstinence-induced depression by regulating biochemical and GRIN2A, GRIN2B gene expression of NMDA receptor signaling pathway in rats. Neurochemistry international. vol 118. 2019-09-16. PMID:29704590. |
the significant reversal effect of nac on the serotonin level following alcohol abstinence was greater in the hippocampus as compared to the third-day alcohol withdrawal group. |
2019-09-16 |
2023-08-13 |
rat |
| Chao Dong, Ji-Chun Zhang, Qian Ren, Min Ma, Youge Qu, Kai Zhang, Wei Yao, Tamaki Ishima, Hisashi Mori, Kenji Hashimot. Deletion of serine racemase confers D-serine -dependent resilience to chronic social defeat stress. Neurochemistry international. vol 116. 2019-09-10. PMID:29550603. |
in wt mice, csds decreased brain-derived neurotrophic factor (bdnf) expression and phosphorylation/activation of its receptor trkb in prefrontal cortex (pfc), dentate gyrus (dg), and the ca3 region of the hippocampus, but increased bdnf and phosphorylated trkb in the nucleus accumbens (nac). |
2019-09-10 |
2023-08-13 |
mouse |
| Mohaddeseh Ebrahimi-Ghiri, Mohammad Nasehi, Mohammad-Reza Zarrindas. The modulatory role of accumbens and hippocampus D2 receptors in anxiety and memory. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 10. 2019-09-10. PMID:30003299. |
the present study investigated the role of dopamine d2 receptors (d2rs) of the dorsal hippocampus (dh) and the nucleus accumbens (nac) and the effect of their dopaminergic activities on anxiety-like behavior and aversive learning using a test-retest elevated plus-maze (epm) paradigm in male wistar rats. |
2019-09-10 |
2023-08-13 |
rat |
| Alberto Cordella, Paraskevi Krashia, Annalisa Nobili, Annabella Pignataro, Livia La Barbera, Maria Teresa Viscomi, Alessandro Valzania, Flavio Keller, Martine Ammassari-Teule, Nicola Biagio Mercuri, Nicola Berretta, Marcello D'Ameli. Dopamine loss alters the hippocampus-nucleus accumbens synaptic transmission in the Tg2576 mouse model of Alzheimer's disease. Neurobiology of disease. vol 116. 2019-09-06. PMID:29778899. |
the functional loop involving the ventral tegmental area (vta), dorsal hippocampus and nucleus accumbens (nac) plays a pivotal role in the formation of spatial memory and persistent memory traces. |
2019-09-06 |
2023-08-13 |
mouse |
| Alberto Cordella, Paraskevi Krashia, Annalisa Nobili, Annabella Pignataro, Livia La Barbera, Maria Teresa Viscomi, Alessandro Valzania, Flavio Keller, Martine Ammassari-Teule, Nicola Biagio Mercuri, Nicola Berretta, Marcello D'Ameli. Dopamine loss alters the hippocampus-nucleus accumbens synaptic transmission in the Tg2576 mouse model of Alzheimer's disease. Neurobiology of disease. vol 116. 2019-09-06. PMID:29778899. |
importantly, the glutamatergic transmission from the hippocampus to the nac core is also impaired. |
2019-09-06 |
2023-08-13 |
mouse |
| Manoj P Dandekar, Ashwini Saxena, Giselli Scaini, Joo Hyun Shin, Agata Migut, Vijayasree Vayalanellore Giridharan, Yuzhi Zhou, Tatiana Barichello, Jair C Soares, Joao Quevedo, Albert J Feno. Medial Forebrain Bundle Deep Brain Stimulation Reverses Anhedonic-Like Behavior in a Chronic Model of Depression: Importance of BDNF and Inflammatory Cytokines. Molecular neurobiology. vol 56. issue 6. 2019-08-29. PMID:30317434. |
interestingly, decreased levels of bdnf in the cus animals were augmented in the plasma, csf, and hippocampus following mfb-dbs, but remained unaltered in the nucleus accumbens (nac). |
2019-08-29 |
2023-08-13 |
rat |
| Manoj P Dandekar, Ashwini Saxena, Giselli Scaini, Joo Hyun Shin, Agata Migut, Vijayasree Vayalanellore Giridharan, Yuzhi Zhou, Tatiana Barichello, Jair C Soares, Joao Quevedo, Albert J Feno. Medial Forebrain Bundle Deep Brain Stimulation Reverses Anhedonic-Like Behavior in a Chronic Model of Depression: Importance of BDNF and Inflammatory Cytokines. Molecular neurobiology. vol 56. issue 6. 2019-08-29. PMID:30317434. |
while multiplex assay revealed no change in the neuronal levels of inflammatory cytokines including il-1α, il-4, il-10, il-12, il-13, and il-17 in the neuroanatomical framework of the hippocampus and nac, increased levels of il-1β, il-2, il-5, il-6, il-7, il-18, tnf-α, and inf-γ were seen in these brain structures after cus and were differentially modulated in the presence of mfb stimulation. |
2019-08-29 |
2023-08-13 |
rat |
| De-Quan Wang, Xin-Ling Wang, Chong-Yang Wang, Yuan Wang, Su-Xia Li, Ke-Zhi Li. Effects of chronic cocaine exposure on the circadian rhythmic expression of the clock genes in reward-related brain areas in rats. Behavioural brain research. vol 363. 2019-08-26. PMID:30682435. |
in cocaine-treated rats, rper1 expression in the suprachiasmatic nucleus (scn), prefrontal cortex (pfc) and ventral tegmental area (vta); rper2 expression in the nucleus accumbens (nac) shell and hippocampus; rper3 expression in the nac core; rcry expression in the scn and pfc; rbmal1 expression in the scn and nac core showed robust circadian rhythms that were essentially identical to those in control rats. |
2019-08-26 |
2023-08-13 |
human |
| De-Quan Wang, Xin-Ling Wang, Chong-Yang Wang, Yuan Wang, Su-Xia Li, Ke-Zhi Li. Effects of chronic cocaine exposure on the circadian rhythmic expression of the clock genes in reward-related brain areas in rats. Behavioural brain research. vol 363. 2019-08-26. PMID:30682435. |
a blunting of circadian oscillations of rper1 expression occurred in the nac core and shell and hippocampus; of rper2 expression occurred in the scn, pfc, nac core and hippocampus; of rper3 expression occurred in the scn, pfc, nac shell, hippocampus and vta; of rcry expression occurred in the nac core and shell, hippocampus and vta; of rbmal1 expression occurred in the pfc, nac shell, hippocampus and vta in cocaine - treated rats. |
2019-08-26 |
2023-08-13 |
human |
| De-Quan Wang, Xin-Ling Wang, Chong-Yang Wang, Yuan Wang, Su-Xia Li, Ke-Zhi Li. Effects of chronic cocaine exposure on the circadian rhythmic expression of the clock genes in reward-related brain areas in rats. Behavioural brain research. vol 363. 2019-08-26. PMID:30682435. |
these rhythm changes accompanied by significant increase in rper1, rper2, rper3 and rbmal1 in the pfc, rper1, rper2 and rbmal1 in the hippocampus; significant decrease in rper2, rper3 and rcry in the scn, rper3, rcry, rbmal1 and rclock in the nac core compared to control rats. |
2019-08-26 |
2023-08-13 |
human |
| Sean J Reed, Christopher K Lafferty, Jesse A Mendoza, Angela K Yang, Thomas J Davidson, Logan Grosenick, Karl Deisseroth, Jonathan P Brit. Coordinated Reductions in Excitatory Input to the Nucleus Accumbens Underlie Food Consumption. Neuron. vol 99. issue 6. 2019-07-30. PMID:30146308. |
here we compare the activity profiles of amygdala, hippocampal, and thalamic inputs to the nac shell in mice performing a cued reward-seeking task using gcamp-based fiber photometry. |
2019-07-30 |
2023-08-13 |
mouse |
| Anna Beyeler, Chia-Jung Chang, Margaux Silvestre, Clémentine Lévêque, Praneeth Namburi, Craig P Wildes, Kay M Ty. Organization of Valence-Encoding and Projection-Defined Neurons in the Basolateral Amygdala. Cell reports. vol 22. issue 4. 2019-07-15. PMID:29386133. |
accumulating evidence supports the notion that different bla projections distinctly alter motivated behavior, including projections to the nucleus accumbens (nac), medial aspect of the central amygdala (cem), and ventral hippocampus (vhpc). |
2019-07-15 |
2023-08-13 |
Not clear |
| Elizabeth M Doncheck, Madalyn Hafenbreidel, Sarah A Ruder, Michael K Fitzgerald, Lilith Torres, Devin Muelle. bFGF expression is differentially regulated by cocaine seeking versus extinction in learning-related brain regions. Learning & memory (Cold Spring Harbor, N.Y.). vol 25. issue 8. 2019-07-02. PMID:30012881. |
therefore, we used the conditioned place preference (cpp) paradigm to assess bfgf expression following cocaine-associated cpp or extinction of that cpp within the mpfc, nucleus accumbens (nac), hippocampus (hipp), and basolateral amygdala (bla). |
2019-07-02 |
2023-08-13 |
Not clear |
| C Jiang, W-J Lin, M Sadahiro, B Labonté, C Menard, M L Pfau, C A Tamminga, G Turecki, E J Nestler, S J Russo, S R Salto. VGF function in depression and antidepressant efficacy. Molecular psychiatry. vol 23. issue 7. 2019-06-17. PMID:29158577. |
here, we show that vgf (non-acronymic), which is robustly regulated by bdnf/trkb signaling, is downregulated in hippocampus (male/female) and upregulated in nucleus accumbens (nac) (male) in depressed human subjects and in mice subjected to chronic social defeat stress (csds). |
2019-06-17 |
2023-08-13 |
mouse |