| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Atefeh Bakhtazad, Nasim Vousooghi, Mohammad Nasehi, Nima Sanadgol, Behzad Garmabi, Mohammad Reza Zarrindas. The effect of microinjection of CART 55-102 into the nucleus accumbens shell on morphine-induced conditioned place preference in rats: Involvement of the NMDA receptor. Peptides. vol 129. 2021-06-07. PMID:32335205. |
we also measured nr1 subunit expressions of the n-methyl-d-aspartate (nmda) receptor in various parts of the reward pathway (nac, prefrontal cortex and hippocampus) after conditioning tests. |
2021-06-07 |
2023-08-13 |
rat |
| Atefeh Bakhtazad, Nasim Vousooghi, Mohammad Nasehi, Nima Sanadgol, Behzad Garmabi, Mohammad Reza Zarrindas. The effect of microinjection of CART 55-102 into the nucleus accumbens shell on morphine-induced conditioned place preference in rats: Involvement of the NMDA receptor. Peptides. vol 129. 2021-06-07. PMID:32335205. |
however, infusion of an aversive dose of cart (5 μg/side) prior to the rewarding dose of morphine (5 mg/kg) produced neither cpp nor cpa and nr1 in the nac and hippocampus decreased significantly. |
2021-06-07 |
2023-08-13 |
rat |
| Gui-Ying Zan, Xiang Sun, Yu-Jun Wang, Rui Liu, Chen-Yao Wang, Wei-Jia Du, Liu-Bin Guo, Jing-Rui Chai, Qing-Lin Li, Zhi-Qiang Liu, Jing-Gen Li. Amygdala dynorphin/κ opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress. Acta pharmacologica Sinica. 2021-05-26. PMID:34035484. |
we further revealed that social defeat stress activated c-fos and erk signaling in the amygdala without affecting the nac, hippocampus and hypothalamus, and erk activation was blocked by systemic injection of norbni. |
2021-05-26 |
2023-08-13 |
mouse |
| Paula Moyano, Javier Sanjuan, José Manuel García, María José Anadon, Maria Victoria Naval, Emma Sola, Jimena García, María Teresa Frejo, Javier Del Pin. Dysregulation of prostaglandine E2 and BDNF signaling mediated by estrogenic dysfunction induces primary hippocampal neuronal cell death after single and repeated paraquat treatment. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 144. 2021-05-21. PMID:32738378. |
primary hippocampal wildtype or βapp-tau silenced cells were co-treated with pq with or without e2, n-acetylcysteine (nac), ns-398 (cyclooxygenase-2 inhibitor), mf63 (pges-1 inhibitor) and/or recombinant brain-derived neurotrophic factor (bdnf) during one- and fourteen-days to studied pq effect on prostaglandin e2 (pge2) and bdnf signaling and their involvement in hyperphosphorylated tau (ptau) and amyloid-beta (aβ) protein formation, and oxidative stress generation, that lead to neuronal cell loss through estrogenic disruption, as a possible mechanism of cognitive dysfunctions produced by pq. |
2021-05-21 |
2023-08-13 |
Not clear |
| Carmen Freire-Cobo, Jun Wan. Dietary phytochemicals modulate experience-dependent changes in Neurexin gene expression and alternative splicing in mice after chronic variable stress exposure. European journal of pharmacology. vol 883. 2021-05-18. PMID:32663544. |
we found that cvs differentially triggers the region-specific gene expression of nrxns in mice nucleus accumbens (nac) and hippocampus (hipp). |
2021-05-18 |
2023-08-13 |
mouse |
| Cheng Xue, Xiao-Hui Li, Meng-Qi Liu, Xing-Cheng Yang, Guo-Hai Li, Ru-Jing Xu, Jia Wang, Wei-Ning Zhan. Enhancing excitatory projections from the ventral subiculum to the nucleus accumbens shell contribute to the MK-801-induced impairment of prepulse inhibition. Neuroscience letters. vol 731. 2021-05-17. PMID:32380142. |
the neural circuits involving the hippocampus and nucleus accumbens (nac) have been studied in rats to uncover the neurochemical and neuroanatomical substrates that regulate ppi. |
2021-05-17 |
2023-08-13 |
rat |
| Katsumasa Muneoka, Yasunori Oda, Masaaki Iwata, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayam. Monoaminergic balances predict non-depression-like phenotype in Learned Helplessness Paradigm. Neuroscience. vol 440. 2021-05-14. PMID:32222554. |
here, we measured the levels of monoamines, including noradrenaline (na), serotonin (5-ht), and dopamine (da), and their metabolites in the medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), hippocampus, nucleus accumbens (nac), amygdala, and striatum in lh, non-lh, and non-manipulated (naïve) rats. |
2021-05-14 |
2023-08-13 |
rat |
| Katsumasa Muneoka, Yasunori Oda, Masaaki Iwata, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayam. Monoaminergic balances predict non-depression-like phenotype in Learned Helplessness Paradigm. Neuroscience. vol 440. 2021-05-14. PMID:32222554. |
compared with naïve rats, non-lh rats showed increased da and homovanillic acid (hva) levels in the amygdala and increased 5-hydroxyindoleacetic acid (5-hiaa) levels in the hippocampus and nac, whereas lh rats exhibited increased hva levels and da turnovers in the hippocampus, decreased 5-hiaa levels in the mpfc, increased da turnovers in the ofc, and decreased da turnovers in the amygdala. |
2021-05-14 |
2023-08-13 |
rat |
| Katsumasa Muneoka, Yasunori Oda, Masaaki Iwata, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayam. Monoaminergic balances predict non-depression-like phenotype in Learned Helplessness Paradigm. Neuroscience. vol 440. 2021-05-14. PMID:32222554. |
changes that occurred in lh or non-lh rats when compared with those in naïve rats suggest that suppressed da activity in the hippocampus and ofc; elevated da activity in the amygdala; and facilitated 5-ht activity in the hippocampus, mpfc, and nac are phenomena related to the expression of a non-depression-like phenotype. |
2021-05-14 |
2023-08-13 |
rat |
| Yang Li, Xin Wang, Nan Li, Liang Qu, Ping Wang, Shun-Nan Ge, Xue-Lian Wan. The NAc lesions disrupted the hippocampus-mPFC theta coherence during intravenous cocaine administration in rats. Neuroscience letters. vol 729. 2021-05-14. PMID:32315712. |
we aimed to examine cocaine-related changes in oscillation synchronization in the hippocampus-mpfc circuit and to explore the role of the nac in oscillation synchronization between the hippocampus and the mpfc during intravenous cocaine administration. |
2021-05-14 |
2023-08-13 |
rat |
| Alexandra Roldán, Maria J Portella, Frederic Sampedro, Anna Alonso-Solís, Salvador Sarró, Mireia Rabella, Eva M Grasa, Enric Álvarez, Rodrigo Rodríguez, Valle Camacho, Alejandro Fernandez-León, Francisco Fuentes, Josefina Pérez-Blanco, Víctor Pérez, Peter Mckenna, Edith Pomarol-Clotet, Iluminada Corripi. Brain metabolic changes in patients with treatment resistant schizophrenia treated with deep brain stimulation: A series of cases. Journal of psychiatric research. vol 127. 2021-05-14. PMID:32485433. |
increments and decrements of brain activity were observed in regions that included the medial prefrontal cortex, the dorsolateral prefrontal cortex, the anterior cingulate cortex, the caudate nucleus, the nac, the hippocampus and the thalamus. |
2021-05-14 |
2023-08-13 |
Not clear |
| Yanjun Meng, Hong Li, Junjie Wang, Yong Xu, Binquan Wan. Cognitive behavioral therapy for patients with mild to moderate depression: Treatment effects and neural mechanisms. Journal of psychiatric research. vol 136. 2021-05-14. PMID:33631654. |
at the baseline, mri data revealed abnormalities in the hippocampus and nucleus accumbens (nac) of patients with mmd, e.g., smaller gray matter volumes of the hippocampus and nucleus accumbens (nac), as well as weaker functional connectivity between nac and the posterior cingulate cortex/precuneus. |
2021-05-14 |
2023-08-13 |
Not clear |
| Yanjun Meng, Hong Li, Junjie Wang, Yong Xu, Binquan Wan. Cognitive behavioral therapy for patients with mild to moderate depression: Treatment effects and neural mechanisms. Journal of psychiatric research. vol 136. 2021-05-14. PMID:33631654. |
moreover, the hippocampus and nac volumes were negatively correlated with the hamd scores in mmd patients. |
2021-05-14 |
2023-08-13 |
Not clear |
| Serguei Liachenko, Jaivijay Ram. Sex differences in the effect of acute administration of nicotine on MRS-measured metabolic profile of the rat brain. Neuroscience research. vol 157. 2021-04-28. PMID:31381938. |
proton mrs was used to monitor changes of specific neurometabolites in hippocampus (hc), nucleus accumbens (nac), and anterior cingulate cortex (acc) of rats of both sexes after single intraperitoneal injection of nicotine. |
2021-04-28 |
2023-08-13 |
rat |
| Yolanda Campos-Jurado, Lucía Martí-Prats, Jose A Morón, Ana Polache, Luis Granero, Lucía Hipólit. Dose-dependent induction of CPP or CPA by intra-pVTA ethanol: Role of mu opioid receptors and effects on NMDA receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 100. 2021-04-28. PMID:31978422. |
finally, modifications of the expression of nmda receptor subunits in the nucleus accumbens (nac) and hippocampus after ethanol-induced cpp were analyzed at the proteomic and transcriptomic levels by western blot and in situ hybridation rnascope techniques, respectively. |
2021-04-28 |
2023-08-13 |
Not clear |
| Chiomah Ezeomah, Kathryn A Cunningham, Sonja J Stutz, Robert G Fox, Natalya Bukreyeva, Kelly T Dineley, Slobodan Paessler, Irma E Cisnero. Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:32165150. |
several innate immune markers, as well as opioid receptors (ors) and intracellular pattern recognition receptors (prrs), were interrogated within nodes of the neurocircuitry involved in oud processes, including the prefrontal cortex (pfc), nucleus accumbens (nac), caudate putamen (cpu), hippocampus (hip) and midbrain (mb). |
2021-04-27 |
2023-08-13 |
rat |
| Marta Celorrio, James Rhodes, Sangeetha Vadivelu, McKenzie Davies, Stuart H Fries. N-acetylcysteine reduces brain injury after delayed hypoxemia following traumatic brain injury. Experimental neurology. vol 335. 2021-04-19. PMID:33065076. |
nac or vehicle administered daily starting 2 h prior to hypoxemia (24 h after controlled cortical impact) for 3 doses in male mice reduced short-term axonal injury and hippocampal neuronal loss. |
2021-04-19 |
2023-08-13 |
mouse |
| Marta Celorrio, James Rhodes, Sangeetha Vadivelu, McKenzie Davies, Stuart H Fries. N-acetylcysteine reduces brain injury after delayed hypoxemia following traumatic brain injury. Experimental neurology. vol 335. 2021-04-19. PMID:33065076. |
at 7 months after injury, nac administered mice had reduced hippocampal neuronal loss but no reduction in lesion volume. |
2021-04-19 |
2023-08-13 |
mouse |
| Sharlene D Newman, Hu Cheng, Dae-Jin Kim, Ashley Schnakenberg-Martin, Ulrike Dydak, Shalmali Dharmadhikari, William Hetrick, Brian O'Donnel. An investigation of the relationship between glutamate and resting state connectivity in chronic cannabis users. Brain imaging and behavior. vol 14. issue 5. 2021-04-13. PMID:31302844. |
the aims of the current preliminary study were to: 1) determine whether dorsal anterior cingulate cortex (dacc) glu is related to rsfc between the dacc and two nodes of the reward network, the nucleus accumbens (nac) and hippocampus (hp); and 2) determine whether cb use interacts with the relationship between dacc glu and rsfc. |
2021-04-13 |
2023-08-13 |
human |
| Shaoqiang Han, Qian Cui, Xiao Wang, Yuyan Chen, Di Li, Liang Li, Xiaonan Guo, Yun-Shuang Fan, Jing Guo, Wei Sheng, Fengmei Lu, Zongling He, Huafu Che. The anhedonia is differently modulated by structural covariance network of NAc in bipolar disorder and major depressive disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 99. 2021-03-31. PMID:31962188. |
apart from these regions, bd patients presented specifically increased structural covariance of nac connected to left hippocampus extending to thalamus. |
2021-03-31 |
2023-08-13 |
human |