| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Salar Vaseghi, Shahram Zarrabian, Abbas Haghparas. Reviewing the role of the orexinergic system and stressors in modulating mood and reward-related behaviors. Neuroscience and biobehavioral reviews. 2022-01-01. PMID:34973302. |
cross-talk between the reward system and orexinergic signaling was also investigated, especially orexinergic signaling in the ventral tegmental area (vta), the nucleus accumbens (nac), and the hippocampus. |
2022-01-01 |
2023-08-13 |
Not clear |
| Salar Vaseghi, Shahram Zarrabian, Abbas Haghparas. Reviewing the role of the orexinergic system and stressors in modulating mood and reward-related behaviors. Neuroscience and biobehavioral reviews. 2022-01-01. PMID:34973302. |
here, we narrowed down our focus on the orexinergic signaling in three brain regions: the vta, nac, and the hippocampus (ca1 region and dentate gyrus) for their prominent role in reward-related behaviors and memory. |
2022-01-01 |
2023-08-13 |
Not clear |
| Thilo Rusche, Jörn Kaufmann, Jürgen Voge. Nucleus accumbens projections: Validity and reliability of fiber reconstructions based on high-resolution diffusion-weighted MRI. Human brain mapping. vol 42. issue 18. 2021-12-03. PMID:34528323. |
for probabilistic fiber tracking the nac as a seed region and the medial prefrontal cortex (mpfc), anterior cingulate cortex (acc), amygdala (amy), hippocampus (hpc), dorsomedial thalamus (dmt) and ventral tegmental area (vta) as target regions were segmented for each subject and both hemispheres. |
2021-12-03 |
2023-08-13 |
human |
| Alexander K Zinsmaier, Yan Dong, Yanhua H Huan. Cocaine-induced projection-specific and cell type-specific adaptations in the nucleus accumbens. Molecular psychiatry. 2021-11-26. PMID:33963288. |
the nucleus accumbens (nac) integrates and prioritizes different emotional and motivational inputs to the reward system by processing convergent glutamatergic projections from the medial prefrontal cortex, basolateral amygdala, ventral hippocampus, and other limbic and paralimbic brain regions. |
2021-11-26 |
2023-08-13 |
Not clear |
| Mariya Tsyglakova, Alisa M Huskey, Emily H Hurst, Natalie M Telep, Mary C Wilding, Meghan E Babington, Jennifer R Rainville, Georgia E Hode. Sex and region-specific effects of variable stress on microglia morphology. Brain, behavior, & immunity - health. vol 18. 2021-11-26. PMID:34820640. |
here we report changes in microglia morphology in the nucleus accumbens (nac) and subregions of the hippocampus (hpc) in both male and female mice following variable stress of 6 or 28 days in duration. |
2021-11-26 |
2023-08-13 |
mouse |
| Alessandra Lintas, Raudel Sánchez-Campusano, Alessandro E P Villa, Agnès Gruart, José M Delgado-Garcí. Operant conditioning deficits and modified local field potential activities in parvalbumin-deficient mice. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:33536607. |
recordings from prefrontal cortex, nucleus accumbens (nac) and hippocampus showed significant decreases of the spectral power in beta and gamma bands in pvko compared with wt mice particularly during the performance of the operant conditioning task. |
2021-11-12 |
2023-08-13 |
mouse |
| Laura Hautrive Milanesi, Domenika Rubert Rossato, Jéssica Leandra Oliveira da Rosa, Lívia Ferraz D'avila, Vinicia Garzella Metz, Jéssica Fernanda Wolf, Vanessa B Reis, Diego F de Andrade, Louise Jank, Ruy C R Beck, Cristiane de B da Silva, Marilise E Burge. Topiramate-chitosan nanoparticles prevent morphine reinstatement with no memory impairment: Dopaminergic and glutamatergic molecular aspects in rats. Neurochemistry international. vol 150. 2021-11-11. PMID:34390773. |
tpm-cs-np treatment decreased d1r, d3r and glua1 and increased dat in the nac, decreasing glua1 and increasing d2 and dat in the dorsal hippocampus. |
2021-11-11 |
2023-08-13 |
rat |
| Bai-Chuang Shyu, Zhi-Yue Gao, José Jiun-Shian Wu, Alan Bo Han He, Cai-N Cheng, Andrew Chih Wei Huan. Methamphetamine and Modulation Functionality of the Prelimbic Cortex for Developing a Possible Treatment of Alzheimer's Disease in an Animal Model. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744692. |
this study examined whether a low dose of mamph can induce conditioned taste aversion (cta) learning, or can increase plasma corticosterone levels, neural activity, and neural plasticity in the medial prefrontal cortex (mpfc) (responsible for cognitive function), the nucleus accumbens (nac) and the amygdala (related to rewarding and aversive emotion), and the hippocampus (responsible for spatial learning). |
2021-11-10 |
2023-08-13 |
rat |
| Bai-Chuang Shyu, Zhi-Yue Gao, José Jiun-Shian Wu, Alan Bo Han He, Cai-N Cheng, Andrew Chih Wei Huan. Methamphetamine and Modulation Functionality of the Prelimbic Cortex for Developing a Possible Treatment of Alzheimer's Disease in an Animal Model. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744692. |
furthermore, the excitations or lesions of the prelimbic cortex (prl) can affect mamph-induced cta learning, plasma corticosterone levels, and neural activity or plasticity in the mpfc [i.e., prl, infralimbic cortex (il), cingulate cortex 1 (cg1)], the nac, the amygdala [i.e., basolateral amygdala (bla) and central amygdala (cea)], and the hippocampus [i.e., ca1, ca2, ca3, and dentate gyrus (dg)]. |
2021-11-10 |
2023-08-13 |
rat |
| Giorgia Boero, Ryan E Tyler, Caroline A Todd, Todd K O'Buckley, Irina Balan, Joyce Besheer, A Leslie Morro. (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) regulation of hypothalamic and extrahypothalamic corticotropin releasing factor (CRF): Sexual dimorphism and brain region specificity in Sprague Dawley rats. Neuropharmacology. vol 186. 2021-11-05. PMID:33460689. |
crf neurons are found mainly in the hypothalamus, but crf positive cells and crf1 receptors are also found in extrahypothalamic structures, including amygdala (cea), hippocampus, nac and vta. |
2021-11-05 |
2023-08-13 |
rat |
| Zeinab Khastkhodaei, Muthuraman Muthuraman, Jenq-Wei Yang, Sergiu Groppa, Heiko J Luhman. Functional and directed connectivity of the cortico-limbic network in mice in vivo. Brain structure & function. vol 226. issue 3. 2021-11-02. PMID:33442810. |
central structures of this cortico-limbic network are ventral hippocampus (vhc), medial prefrontal cortex (pfc), basolateral amygdala (bla) and nucleus accumbens (nac). |
2021-11-02 |
2023-08-13 |
mouse |
| Elaheh Soleimanpour, Jorge R Bergado Acosta, Peter Landgraf, Dana Mayer, Evelyn Dankert, Daniela C Dieterich, Markus Fend. Regulation of CREB Phosphorylation in Nucleus Accumbens after Relief Conditioning. Cells. vol 10. issue 2. 2021-10-12. PMID:33530478. |
forty-five minutes or 6 h after conditioning, samples of five different brain regions, namely the prefrontal cortex, nucleus accumbens (nac), dorsal striatum, dorsal hippocampus, and amygdala, were collected. |
2021-10-12 |
2023-08-13 |
rat |
| Limeng Huang, Yiwen Chen, Sen Jin, Li Lin, Shumin Duan, Ke Si, Wei Gong, J Julius Zh. Organizational principles of amygdalar input-output neuronal circuits. Molecular psychiatry. 2021-10-06. PMID:34400771. |
using a simplified cell-type- and projection-specific retrograde transsynaptic tracing technique, we scrutinized brain-wide afferent inputs of four major output neuronal groups in the amygdalar basolateral complex (bla) that project to the bed nucleus of the stria terminals (bnst), ventral hippocampus (vhpc), medial prefrontal cortex (mpfc) and nucleus accumbens (nac), respectively. |
2021-10-06 |
2023-08-13 |
Not clear |
| Eric M Parise, Lyonna F Parise, Omar K Sial, Astrid M Cardona-Acosta, Trevonn M Gyles, Barbara Juarez, Dipesh Chaudhury, Ming-Hu Han, Eric J Nestler, Carlos A Bolaños-Guzmá. The Resilient Phenotype Induced by Prophylactic Ketamine Exposure During Adolescence Is Mediated by the Ventral Tegmental Area-Nucleus Accumbens Pathway. Biological psychiatry. vol 90. issue 7. 2021-09-27. PMID:34247781. |
recent evidence showed that ket reverses stress-induced (i.e., depressive-like) deficits within major mesocorticolimbic regions, such as the prefrontal cortex, nucleus accumbens (nac), and hippocampus, in adult rodents. |
2021-09-27 |
2023-08-13 |
Not clear |
| Susanne Nikolaus, Markus Beu, Hans-Jörg Wittsack, Anja Müller-Lutz, Christina Antke, Hubertus Hautzel, Yuriko Mori, Eduards Mamlins, Gerald Antoch, Hans-Wilhelm Mülle. GABAergic and glutamatergic effects on nigrostriatal and mesolimbic dopamine release in the rat. Reviews in the neurosciences. vol 31. issue 6. 2021-09-24. PMID:32619197. |
in these studies, [123i]iodobenzamide binding to the d2/3r was mesured in nucleus accumbens (nac), caudateputamen (cp), substantia nigra/ventral tegmental area (sn/vta), frontal (fc), motor (mc) and parietal cortex (pc) as well as anterior (ahipp) and posterior hippocampus (phipp) with small animal spect in baseline and after injection of either the gabaar agonist muscimol (1 mg/kg), the gabaar antagonist bicuculline (1 mg/kg), the nmdar agonist d-cycloserine (20 mg/kg) or the nmdar antagonist amantadine (40 mg/kg). |
2021-09-24 |
2023-08-13 |
rat |
| Talia Sabran-Cohen, Uri Bright, Tomer Mizrachi Zer-Aviv, Irit Akira. Rapamycin prevents the long-term impairing effects of adolescence Δ-9-tetrahydrocannabinol on memory and plasticity in male rats. The European journal of neuroscience. vol 54. issue 6. 2021-09-24. PMID:34405459. |
thirty days after the last injection, rats were tested for short-term and working memory, anxiety-like behaviour, and plasticity in the pathways projecting from the ventral subiculum (vsub) of the hippocampus to the prefrontal cortex (pfc) and nucleus accumbens (nac). |
2021-09-24 |
2023-08-13 |
rat |
| Qing Shang, Min Liang, Jing Xiao, Baoyao Gao, Hongyan Qian, Jing Wang, Gang Chen, Jie Fang, Tao Li, Xinshe Li. LB100 attenuates methamphetamine-induced behavioral sensitization by inhibiting the Raf1-ERK 1/2 cascade in the caudate putamen. Neuroreport. vol 32. issue 12. 2021-09-20. PMID:34102646. |
in addition, western blot was used to examine the levels of p-raf1 (ser 259) and p-erk 1/2 (thr 202/tyr 204) in the cpu, hippocampus (hip) and nucleus accumbens (nac). |
2021-09-20 |
2023-08-13 |
mouse |
| Titikorn Chunchai, Puntarik Keawtep, Apiwan Arinno, Napatsorn Saiyasit, Dillon Prus, Nattayaporn Apaijai, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. A combination of an antioxidant with a prebiotic exerts greater efficacy than either as a monotherapy on cognitive improvement in castrated-obese male rats. Metabolic brain disease. vol 35. issue 8. 2021-09-02. PMID:32676884. |
interestingly, a combination of nac and inulin had the greatest beneficial effect on cognitive function by synergistically reducing hippocampal inflammation and ameliorating glial dysmorphology. |
2021-09-02 |
2023-08-13 |
rat |
| Shirley Alteba, Tomer Mizrachi Zer-Aviv, Adi Tenenhaus, Gilad Ben David, Jacob Adelman, Cecilia J Hillard, Ravid Doron, Irit Akira. Antidepressant-like effects of URB597 and JZL184 in male and female rats exposed to early life stress. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 39. 2021-08-26. PMID:32891517. |
faah and magl inhibitors during late-adolescence prevented: (i) the long-term effects of els on depression- and anxiety-like behavior and the impairment in social behavior and neuronal plasticity in males and females; (ii) els-induced alterations in magl activity in males' hippocampus and females' hippocampus and nac; and (iii) els-induced alterations in bdnf in males' hippocampus and nac and females' hippocampus. |
2021-08-26 |
2023-08-13 |
rat |
| Fabricia Petronilho, Leonardo Tenfen, Amanda Della Giustina, Larissa Joaquim, Michele Novochadlo, Aloir Neri de Oliveira Junior, Erick Bagio, Mariana Pereira de Souza Goldim, Raquel Jaconi de Carli, Sandra Regina Santana de Aguiar Bonfante, Kiuanne Lino Lobo Metzker, Samara Muttini, Thayná Marinho Dos Santos, Mariana Pacheco de Oliveira, Nicole Alessandra Engel, Gislaine Tezza Rezin, Luiz Alberto Kanis, Tatiana Barichell. Gold nanoparticles potentiates N-acetylcysteine effects on neurochemicals alterations in rats after polymicrobial sepsis. Journal of drug targeting. vol 28. issue 4. 2021-08-18. PMID:31594390. |
aunp + nac association and nac isolated treatment decreased oxidative stress to lipids in both brain structures, while protein oxidation decreased only in the hippocampus of aunp + nac association-treated animals. |
2021-08-18 |
2023-08-13 |
rat |