| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
in vivo microdialysis was used in behaving rats to measure extracellular concentration of 5-ht in the hippocampus and the nac. |
2002-08-08 |
2023-08-12 |
rat |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
cocaine, at a dose that activates behavior, increases 5-ht levels in the hippocampus and in the nac, and 2.) |
2002-08-08 |
2023-08-12 |
rat |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
5-ht(1a)-receptor antagonism can cause a dissociation of the hippocampal and nac 5-ht activity from behavioral activation after cocaine. |
2002-08-08 |
2023-08-12 |
rat |
| Y Gedeon, G T Ramesh, P J Wellman, A L Jadha. Changes in mesocorticolimbic dopamine and D1/D2 receptor levels after low level lead exposure: a time course study. Toxicology letters. vol 123. issue 2-3. 2002-01-16. PMID:11641049. |
this study examined pb-induced changes in the temporal profile of d1/d2 receptor protein and da levels in the nucleus accumbens (nac), hippocampus (hip), and the frontal cortex (fc). |
2002-01-16 |
2023-08-12 |
rat |
| M M Kraus, H Pras. The nitric oxide system modulates the in vivo release of acetylcholine in the nucleus accumbens induced by stimulation of the hippocampal fornix/fimbria-projection. The European journal of neuroscience. vol 14. issue 7. 2001-12-07. PMID:11683902. |
nerve signals from the hippocampus to the nucleus accumbens (nac) are transmitted through a glutamatergic pathway via the fornix/fimbria fibres. |
2001-12-07 |
2023-08-12 |
rat |
| M M Kraus, H Pras. The nitric oxide system modulates the in vivo release of acetylcholine in the nucleus accumbens induced by stimulation of the hippocampal fornix/fimbria-projection. The European journal of neuroscience. vol 14. issue 7. 2001-12-07. PMID:11683902. |
the released no seems to exert, via cgmp, a potent facilitatory role in the transduction and processing of signals from the hippocampus within the nac, while the pde 5 decreases the effects of no. |
2001-12-07 |
2023-08-12 |
rat |
| M D Lapiz, A Fulford, S Muchimapura, R Mason, T Parker, C A Marsde. Influence of postweaning social isolation in the rat on brain development, conditioned behaviour and neurotransmission. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 87. issue 6. 2001-12-04. PMID:11534200. |
isolation-reared rats have enhanced presynaptic dopamine (da) and 5-ht function in the nucleus accimbens (nac) associated with decreased presynaptic 5-ht function in the frontal cortex and hippocampus. |
2001-12-04 |
2023-08-12 |
human |
| M A McLean, F G Woermann, R J Simister, G J Barker, J S Dunca. In vivo short echo time 1H-magnetic resonance spectroscopic imaging (MRSI) of the temporal lobes. NeuroImage. vol 14. issue 2. 2001-09-06. PMID:11467922. |
the concentration of n-acetyl aspartate plus n-acetyl aspartyl glutamate (nac) was not found to vary significantly along the length of the hippocampus. |
2001-09-06 |
2023-08-12 |
Not clear |
| B Roozendaal, D J de Quervain, B Ferry, B Setlow, J L McGaug. Basolateral amygdala-nucleus accumbens interactions in mediating glucocorticoid enhancement of memory consolidation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 7. 2001-06-28. PMID:11264325. |
the nac also receives direct projections from the hippocampus and, therefore, may be a site of convergence of bla and hippocampal influences in modulating memory consolidation. |
2001-06-28 |
2023-08-12 |
rat |
| S B Floresco, C D Blaha, C R Yang, A G Phillip. Modulation of hippocampal and amygdalar-evoked activity of nucleus accumbens neurons by dopamine: cellular mechanisms of input selection. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 8. 2001-06-07. PMID:11306637. |
inputs from multiple sites in the telencephalon, including the hippocampus and basolateral amygdala (bla), converge on neurons in the nucleus accumbens (nac), and dopamine (da) is believed to play an essential role in the amplification and gating of these different limbic inputs. |
2001-06-07 |
2023-08-12 |
Not clear |
| S B Floresco, C D Blaha, C R Yang, A G Phillip. Modulation of hippocampal and amygdalar-evoked activity of nucleus accumbens neurons by dopamine: cellular mechanisms of input selection. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 8. 2001-06-07. PMID:11306637. |
these data suggest that increases in mesoaccumbens da efflux by hippocampal afferents to the nac play a critical role in an input selection mechanism, which can ensure preferential responding to the information conveyed from the hippocampus to the ventral striatum. |
2001-06-07 |
2023-08-12 |
Not clear |
| F I Tarazi, K Zhang, R J Baldessarin. Long-term effects of olanzapine, risperidone, and quetiapine on dopamine receptor types in regions of rat brain: implications for antipsychotic drug treatment. The Journal of pharmacology and experimental therapeutics. vol 297. issue 2. 2001-05-21. PMID:11303062. |
olanzapine and risperidone, but not quetiapine, significantly increased d(2) binding in medial prefrontal cortex (mpc; 67% and 34%), caudate-putamen (cpu; average 42%, 25%), nucleus accumbens (nac; 37%, 28%), and hippocampus (hip; 53%, 30%). |
2001-05-21 |
2023-08-12 |
rat |
| C D Stine, W Lu, M E Wol. Expression of AMPA receptor flip and flop mRNAs in the nucleus accumbens and prefrontal cortex after neonatal ventral hippocampal lesions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 3. 2001-04-19. PMID:11166516. |
the present study examined alpha-amino-3-hydroxy-5-methylisoxazole- 4-priopionate (ampa) receptor expression in the prefrontal cortex (pfc) and nucleus accumbens (nac) using a rat model of schizophrenia in which excitotoxic lesions of ventral hippocampus (vh) on postnatal day (pd) 7 lead to the postpubertal emergence of behavioral abnormalities that resemble schizophrenic symptoms. |
2001-04-19 |
2023-08-12 |
rat |
| T R Franklin, J P Druha. Involvement of the nucleus accumbens and medial prefrontal cortex in the expression of conditioned hyperactivity to a cocaine-associated environment in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 6. 2001-01-04. PMID:11063919. |
this study examined the roles of the nucleus accumbens (nac), medial prefrontal cortex, basolateral amygdala, and ventral subiculum of the hippocampus in the expression of pavlovian conditioned hyperactivity responses to cocaine-related stimuli. |
2001-01-04 |
2023-08-12 |
rat |
| N D Halim, N R Swerdlo. Distributed neurodegenerative changes 2-28 days after ventral hippocampal excitotoxic lesions in rats. Brain research. vol 873. issue 1. 2000-10-12. PMID:10915811. |
amino-cupric-silver staining demonstrated degenerative changes throughout the hippocampus, and in hippocampal efferent projections to forebrain structures, including the septal nucleus and nucleus accumbens (nac), and within the olfactory tubercle (ot) and orbital cortex. |
2000-10-12 |
2023-08-12 |
rat |
| S Cuzzocrea, E Mazzon, G Costantino, I Serraino, L Dugo, G Calabrò, G Cucinotta, A De Sarro, A P Caput. Beneficial effects of n-acetylcysteine on ischaemic brain injury. British journal of pharmacology. vol 130. issue 6. 2000-09-13. PMID:10903958. |
nac also attenuated the increase in the brain levels of malondialdehyde (mda) and the increase in the hippocampus of myeloperoxidase (mpo) caused by cerebral ischaemia. |
2000-09-13 |
2023-08-12 |
Not clear |
| S Puglisi-Allegra, S Cabib, T Pascucci, R Ventura, F Cali, V Roman. Dramatic brain aminergic deficit in a genetic mouse model of phenylketonuria. Neuroreport. vol 11. issue 6. 2000-07-17. PMID:10817622. |
results indicated a significant reduction of 5-ht levels and metabolism in prefrontal cortex (pfc), cingulate cortex (cg), nucleus accumbens (nac), caudate putamen (cp), hippocampus (hip) and amygdala (amy). |
2000-07-17 |
2023-08-12 |
mouse |
| S F Ali, N Thiriet, J Zwille. Acute ibogaine injection induces expression of the immediate early genes, egr-1 and c-fos, in mouse brain. Brain research. Molecular brain research. vol 74. issue 1-2. 2000-02-15. PMID:10640697. |
a single injection of ibo produced a significant increase of egr-1 messenger rna induction in nucleus accumbens (nac), caudate-putamen (cpu), frontal cortex (fcx), septum, dentate gyrus (dg) and ca3 region of hippocampus, whereas c-fos gene was induced in cpu, fcx, dg, septum and ca1 region of hippocampus. |
2000-02-15 |
2023-08-12 |
mouse |
| J G Culvenor, C A McLean, S Cutt, B C Campbell, F Maher, P Jäkälä, T Hartmann, K Beyreuther, C L Masters, Q X L. Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid. The American journal of pathology. vol 155. issue 4. 1999-11-04. PMID:10514400. |
using antibodies to alphasn(75-91) to label cortical and hippocampal sections of pathologically proven ad cases, we found no evidence for nac in abeta amyloid plaques. |
1999-11-04 |
2023-08-12 |
human |
| F I Tarazi, E C Tomasini, R J Baldessarin. Postnatal development of dopamine D1-like receptors in rat cortical and striatolimbic brain regions: An autoradiographic study. Developmental neuroscience. vol 21. issue 1. 1999-07-14. PMID:10077701. |
postnatal development of dopamine d1-like (d1/d5) receptors in rat caudate-putamen (cpu), nucleus accumbens (nac), hippocampus, frontal and entorhinal cerebral cortex was assessed between postnatal days (pd) 7-60 by in vitro receptor autoradiography. |
1999-07-14 |
2023-08-12 |
rat |