| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lu Gan, Tomas L Falzone, Kehong Zhang, Marcelo Rubinstein, Ross J Baldessarini, Frank I Taraz. Enhanced expression of dopamine D(1) and glutamate NMDA receptors in dopamine D(4) receptor knockout mice. Journal of molecular neuroscience : MN. vol 22. issue 3. 2004-06-17. PMID:14997010. |
the findings suggest that d1, d4, and nmda receptors might interact functionally and that developmental absence of d4 receptors might trigger compensatory mechanisms that enhance expression of d1 receptors in nac and cpu, and nmda receptors in nac, cpu, and hippocampus. |
2004-06-17 |
2023-08-12 |
mouse |
| Roman Duncko, Marek Schwendt, Daniela Jezov. Altered glutamate receptor and corticoliberin gene expression in brain regions related to hedonic behavior in rats. Pharmacology, biochemistry, and behavior. vol 76. issue 1. 2004-05-10. PMID:13679212. |
in the nucleus accumbens (nac) and the hippocampus of anhedonic animals, higher mrna levels of nr2a subunit compared to those of hedonic rats were detected. |
2004-05-10 |
2023-08-12 |
rat |
| M J Cano-Cebrián, T Zornoza-Sabina, C Guerri, A Polache, L Graner. Acamprosate blocks the increase in dopamine extracellular levels in nucleus accumbens evoked by chemical stimulation of the ventral hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 368. issue 4. 2004-02-06. PMID:13680089. |
neurochemical studies show that chemical stimulation (using nmda) of the ventral subiculum (vsub) of the hippocampus produces robust and sustained increases in extracellular da levels in the nac, an effect mediated through ionotropic glutamate (iglu) receptors. |
2004-02-06 |
2023-08-12 |
rat |
| M J Cano-Cebrián, T Zornoza-Sabina, C Guerri, A Polache, L Graner. Acamprosate blocks the increase in dopamine extracellular levels in nucleus accumbens evoked by chemical stimulation of the ventral hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 368. issue 4. 2004-02-06. PMID:13680089. |
the present study examines whether acamprosate locally infused in the nac of rats could block or attenuate the increase in nac extracellular da elicited by chemical stimulation (with 5 mm nmda) of the ventral subiculum of the hippocampus. |
2004-02-06 |
2023-08-12 |
rat |
| Xilu Jiao, William P Paré, Shanaz Tejani-But. Strain differences in the distribution of dopamine transporter sites in rat brain. Progress in neuro-psychopharmacology & biological psychiatry. vol 27. issue 6. 2004-01-05. PMID:14499307. |
while the binding of [3h]-gbr to dat sites was significantly decreased in the nucleus accumbens (nac), the amygdala, the ventral tegmental area (vta), and the reticular part of the substantia nigra (p<.05), the binding was significantly increased in the hippocampal subregions and the hypothalamus (p<.05) in wky rats compared to the other two strains. |
2004-01-05 |
2023-08-12 |
rat |
| Yasuo Kajimoto, Osamu Shirakawa, Xian-Hao Lin, Takeshi Hashimoto, Noboru Kitamura, Naoya Murakami, Toru Takumi, Kiyoshi Maed. Synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP) is expressed differentially in phencyclidine-treated rats and is increased in the nucleus accumbens of patients with schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 10. 2003-12-05. PMID:12784099. |
quantitative reverse transcriptase (rt)-pcr analysis showed that sapap1 mrna had increased significantly in rat nac (p<0.0001) and hippocampus (p<0.01) 24 h after a pcp (10 mg/kg) injection as compared to the controls. |
2003-12-05 |
2023-08-12 |
human |
| A Charara, A A Grac. Dopamine receptor subtypes selectively modulate excitatory afferents from the hippocampus and amygdala to rat nucleus accumbens neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 8. 2003-09-12. PMID:12799620. |
we examined the effects of dopamine (da) d1 and d2 selective drugs on the responses evoked in the nac shell neurons recorded in vitro by stimulation of hippocampal and amygdaloid afferents. |
2003-09-12 |
2023-08-12 |
rat |
| Makoto Inoue, Masayoshi Mishina, Hiroshi Ued. Locus-specific rescue of GluRepsilon1 NMDA receptors in mutant mice identifies the brain regions important for morphine tolerance and dependence. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 16. 2003-09-03. PMID:12878694. |
in c57bl/6j mice treated with chronic morphine after tolerance paradigm, the glurepsilon1 protein expression significantly increased in periaqueductal gray matter (pag), ventral tegmental area (vta) and nucleus accumbens (nac), but not amygdala or hippocampus. |
2003-09-03 |
2023-08-12 |
mouse |
| Hui Tian, Guangyi Zhang, Hongchun Li, Quanguang Zhan. Antioxidant NAC and AMPA/KA receptor antagonist DNQX inhibited JNK3 activation following global ischemia in rat hippocampus. Neuroscience research. vol 46. issue 2. 2003-07-25. PMID:12767482. |
antioxidant nac and ampa/ka receptor antagonist dnqx inhibited jnk3 activation following global ischemia in rat hippocampus. |
2003-07-25 |
2023-08-12 |
rat |
| C P Müller, R J Carey, J B Salloum, J P Husto. Serotonin1A-receptor agonism attenuates the cocaine-induced increase in serotonin levels in the hippocampus and nucleus accumbens but potentiates hyperlocomotion: an in vivo microdialysis study. Neuropharmacology. vol 44. issue 5. 2003-06-23. PMID:12668045. |
the hippocampus and the nucleus accumbens (nac) are important structures for the modulation of spontaneous locomotor activity. |
2003-06-23 |
2023-08-12 |
rat |
| C P Müller, R J Carey, J B Salloum, J P Husto. Serotonin1A-receptor agonism attenuates the cocaine-induced increase in serotonin levels in the hippocampus and nucleus accumbens but potentiates hyperlocomotion: an in vivo microdialysis study. Neuropharmacology. vol 44. issue 5. 2003-06-23. PMID:12668045. |
we have previously reported that the 5-ht(1a)-receptor antagonist way 100635 blocked cocaine-induced hyperactivity, while potentiating cocaine-induced 5-ht increases in the hippocampus and the nac. |
2003-06-23 |
2023-08-12 |
rat |
| C P Müller, R J Carey, J B Salloum, J P Husto. Serotonin1A-receptor agonism attenuates the cocaine-induced increase in serotonin levels in the hippocampus and nucleus accumbens but potentiates hyperlocomotion: an in vivo microdialysis study. Neuropharmacology. vol 44. issue 5. 2003-06-23. PMID:12668045. |
in order to further investigate the relationship between extracellular 5-ht concentration and cocaine-induced behaviour, we used in vivo microdialysis to measure the effects of the 5-ht(1a)-receptor agonist 8-oh-dpat on cocaine-induced changes in the extracellular 5-ht concentration in the hippocampus and the nac and on behavioural activity. |
2003-06-23 |
2023-08-12 |
rat |
| C P Müller, R J Carey, J B Salloum, J P Husto. Serotonin1A-receptor agonism attenuates the cocaine-induced increase in serotonin levels in the hippocampus and nucleus accumbens but potentiates hyperlocomotion: an in vivo microdialysis study. Neuropharmacology. vol 44. issue 5. 2003-06-23. PMID:12668045. |
we found that the 5-ht(1a)-receptor agonist 8-oh-dpat attenuated the cocaine-induced increases in 5-ht in the hippocampus and the nac, but potentiated cocaine-induced hyperlocomotion. |
2003-06-23 |
2023-08-12 |
rat |
| C P Müller, R J Carey, J B Salloum, J P Husto. Serotonin1A-receptor agonism attenuates the cocaine-induced increase in serotonin levels in the hippocampus and nucleus accumbens but potentiates hyperlocomotion: an in vivo microdialysis study. Neuropharmacology. vol 44. issue 5. 2003-06-23. PMID:12668045. |
altogether, these observations support an important role of the 5-ht(1a)-receptor in the hippocampus and nac in the modulation of cocaine stimulant effects. |
2003-06-23 |
2023-08-12 |
rat |
| M D S Lapiz, A Fulford, S Muchimapura, R Mason, T Parker, C A Marsde. Influence of postweaning social isolation in the rat on brain development, conditioned behavior, and neurotransmission. Neuroscience and behavioral physiology. vol 33. issue 1. 2003-04-14. PMID:12617300. |
isolation-reared rats have enhanced presynaptic dopamine (da) and 5-ht function in the nucleus accumbens (nac) associated with decreased presynaptic 5-ht function in the frontal cortex and hippocampus. |
2003-04-14 |
2023-08-12 |
human |
| Marco Pistis, Anna Lisa Muntoni, Giuliano Pillolla, Gian Luigi Gess. Cannabinoids inhibit excitatory inputs to neurons in the shell of the nucleus accumbens: an in vivo electrophysiological study. The European journal of neuroscience. vol 15. issue 11. 2002-09-04. PMID:12081659. |
cannabinoid receptors (cb1) are densely expressed in regions that provide excitatory innervation to the nac, such as the amygdala, the cortex and the hippocampus. |
2002-09-04 |
2023-08-12 |
rat |
| W Lu, M Marinelli, D Xu, P F Worley, M E Wol. Amphetamine and cocaine do not increase Narp expression in rat ventral tegmental area, nucleus accumbens or prefrontal cortex, but Narp may contribute to individual differences in responding to a novel environment. The European journal of neuroscience. vol 15. issue 12. 2002-09-04. PMID:12099908. |
immunohistochemical studies demonstrated the existence of narp-positive cells in hippocampus, prefrontal cortex (pfc) and nucleus accumbens (nac), with lower levels of staining in the ventral tegmental area (vta). |
2002-09-04 |
2023-08-12 |
rat |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
neuronal activity in the hippocampus and the nucleus accumbens (nac) depend on serotonergic (5-ht) transmission. |
2002-08-08 |
2023-08-12 |
rat |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
here we describe for the first time a cocaine-induced increase in 5-ht concentration in the hippocampus and the nac parallel to behavioral activation. |
2002-08-08 |
2023-08-12 |
rat |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
in addition, pretreatment with the 5-ht(1a)-receptor antagonist way 100635 blocked the behavioral activation after cocaine while potentiating the 5-ht increase in the hippocampus and the nac. |
2002-08-08 |
2023-08-12 |
rat |