| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kelsey D McDermott, M Agustina Frechou, Jake T Jordan, Sunaina S Martin, J Tiago Gon ßalve. Delayed formation of neural representations of space in aged mice. bioRxiv : the preprint server for biology. 2023-04-10. PMID:37034736. |
the hippocampal dentate gyrus (dg) is important for processing spatial information in the brain and is particularly vulnerable to aging, yet its sparse activity has led to difficulties in assessing changes in this area. |
2023-04-10 |
2023-08-14 |
mouse |
| Luísa Pinto, Joana Macedo, Bruna Araújo, Sandra Anjo, Tiago Silveira-Rosa, Patrícia Patrício, Fábio Teixeira, Bruno Manadas, Ana Joao Rodrigues, Angelo Lepore, António Salgado, Eduardo Gome. Glial-Restricted Precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation. Research square. 2023-04-10. PMID:37034743. |
to examine the role of newly formed glia, we transplanted glial restricted precursors (grps) into the adult hippocampal dentate gyrus (dg), or injected their secreted factors (secretome), into a previously validated transgenic gfap-tk rat line, in which cytogenesis is transiently compromised. |
2023-04-10 |
2023-08-14 |
rat |
| Xiangxian Ma, Qiongyu Li, Guanhong Chen, Junjie Xie, Min Wu, Fantao Meng, Jing Liu, Yong Liu, Di Zhao, Wentao Wang, Dan Wang, Cuilan Liu, Juanjuan Dai, Chen Li, Minghu Cu. Role of Hippocampal miR-132-3p in Modifying the Function of Protein Phosphatase Mg2+/Mn2+-dependent 1 F in Depression. Neurochemical research. 2023-04-10. PMID:37036545. |
our previous study has shown that protein phosphatase mg2+/mn2+-dependent 1f (ppm1f) in the hippocampal dentate gyrus (dg) displays significant regulatory effects in depression-related behaviors. |
2023-04-10 |
2023-08-14 |
mouse |
| Marta Vicente-Rodríguez, Renzo Mancuso, Alba Peris-Yague, Camilla Simmons, Diego Gómez-Nicola, V Hugh Perry, Federico Turkheimer, Simon Lovestone, Christine A Parker, Diana Cas. Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease. Journal of neuroinflammation. vol 20. issue 1. 2023-04-09. PMID:37032328. |
importantly, we show that the selective csf1r inhibitor, jnj-40346527 (jnj527), attenuated the disease-dependent increase in tspo signal, particularly in the dentate gyrus of the hippocampus, where jnj527 attenuated the number of iba1+ microglia and neurons, but not gfap+ astrocytes or endothelial cells. |
2023-04-09 |
2023-08-14 |
mouse |
| Fatih Mete, Signem Eyuboglu, Ayca Vitrinel, Ulkan Kilic, Cihan Suleyman Erdogan, Ertugrul Kilic, Bayram Yilma. Hyperthermia alters neurobehavior by affecting cell proliferation and neuronal survival in young male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2023-04-08. PMID:37029601. |
neuronal survival, apoptosis, and cell proliferation were investigated in cortex, hippocampal dentate gyrus (dg) and ca1 regions, and corpus callosum (cc). |
2023-04-08 |
2023-08-14 |
rat |
| Ling Zhao, Thomas W Mühleisen, Dominique I Pelzer, Bettina Burger, Eva C Beins, Andreas J Forstner, Stefan Herms, Per Hoffmann, Katrin Amunts, Nicola Palomero-Gallagher, Sven Cicho. Relationships between neurotransmitter receptor densities and expression levels of their corresponding genes in the human hippocampus. NeuroImage. 2023-04-08. PMID:37030412. |
we combined in vitro receptor autoradiography and rna sequencing to quantify, in the same tissue samples (7 subjects), the densities of 14 receptors and expression levels of their corresponding 43 genes in the cornu ammonis (ca) and dentate gyrus (dg) of human hippocampus. |
2023-04-08 |
2023-08-14 |
human |
| Lang Wen, Xiaoli Yang, Zujun Wu, Shumei Fu, Yaxi Zhan, Zuolong Chen, Danlei Bi, Yong She. The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus. Cell reports. vol 42. issue 4. 2023-04-07. PMID:37027303. |
furthermore, cd59 deficiency impairs gabaergic synaptic transmission in the hippocampal dentate gyrus (dg). |
2023-04-07 |
2023-08-14 |
Not clear |
| Camille M Fun. Effects of intrauterine growth restriction on embryonic hippocampal dentate gyrus neurogenesis and postnatal critical period of synaptic plasticity that govern learning and memory function. Frontiers in neuroscience. vol 17. 2023-04-03. PMID:37008232. |
effects of intrauterine growth restriction on embryonic hippocampal dentate gyrus neurogenesis and postnatal critical period of synaptic plasticity that govern learning and memory function. |
2023-04-03 |
2023-08-14 |
mouse |
| Camille M Fun. Effects of intrauterine growth restriction on embryonic hippocampal dentate gyrus neurogenesis and postnatal critical period of synaptic plasticity that govern learning and memory function. Frontiers in neuroscience. vol 17. 2023-04-03. PMID:37008232. |
the hippocampus, composed of the dentate gyrus (dg) and cornu ammonis (ca) subregions, is an important gray matter structure critical to learning and memory, and is particularly vulnerable to the chronic hypoxic-ischemic effects of upi. |
2023-04-03 |
2023-08-14 |
mouse |
| Kanza M Khan, Nagalakshmi Balasubramanian, Gabriel Gaudencio, Ruixiang Wang, Govindhasamy Pushpavathi Selvakumar, Louis Kolling, Samantha Pierson, Satya M Tadinada, Ted Abel, Marco Hefti, Catherine A Marcinkiewc. Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer's disease. Acta neuropathologica communications. vol 11. issue 1. 2023-04-03. PMID:37009893. |
loss of 5-ht innervation to the entorhinal cortex and dentate gyrus of the hippocampus was also observed and may have contributed to depressive-like behaviors. |
2023-04-03 |
2023-08-14 |
mouse |
| JiaLing Zhong, ChunLin Li, LuoFang Peng, Yudan Pan, Yong Yang, QuLian Guo, Tao Zhon. Repeated neonatal isoflurane exposure facilitated stress-related fear extinction impairment in male mice and was associated with ΔFosB accumulation in the basolateral amygdala and the hippocampal dentate gyrus. Behavioural brain research. 2023-04-01. PMID:37003493. |
repeated neonatal isoflurane exposure facilitated stress-related fear extinction impairment in male mice and was associated with Δfosb accumulation in the basolateral amygdala and the hippocampal dentate gyrus. |
2023-04-01 |
2023-08-14 |
mouse |
| JiaLing Zhong, ChunLin Li, LuoFang Peng, Yudan Pan, Yong Yang, QuLian Guo, Tao Zhon. Repeated neonatal isoflurane exposure facilitated stress-related fear extinction impairment in male mice and was associated with ΔFosB accumulation in the basolateral amygdala and the hippocampal dentate gyrus. Behavioural brain research. 2023-04-01. PMID:37003493. |
the corticosterone (cort) response during cvs and the immunohistochemical levels of Δfosb and c-fos expression in the basolateral amygdala (bla) and the hippocampal dentate gyrus (dg) after the extinction retrieval test were also investigated. |
2023-04-01 |
2023-08-14 |
mouse |
| Toshinori Yoshioka, Daisuke Yamada, Eri Segi-Nishida, Hiroshi Nagase, Akiyoshi Saito. KNT-127, a selective delta opioid receptor agonist, shows beneficial effects in the hippocampal dentate gyrus of a chronic vicarious social defeat stress mouse model. Neuropharmacology. 2023-03-31. PMID:37001727. |
knt-127, a selective delta opioid receptor agonist, shows beneficial effects in the hippocampal dentate gyrus of a chronic vicarious social defeat stress mouse model. |
2023-03-31 |
2023-08-14 |
mouse |
| Laura J Mahady, Sylvia E Perez, Michael Malek-Ahmadi, Elliott J Mufso. Oligomeric, phosphorylated, and truncated tau and spliceosome pathology within the entorhinal-hippocampal connectome across stages of Alzheimer's disease. The Journal of comparative neurology. 2023-03-29. PMID:36989381. |
here, we used quantitative immunohistochemistry to determine the density of posttranslational oligomeric (toc1 and tnt1), phosphorylated (at8), and late truncated (tauc3) tau epitopes within the mtl subfields including entorhinal cortex (ec) layer ii, subiculum, cornu ammonis (ca) subfields, and dentate gyrus (dg) in subjects who died with a clinical diagnosis of no cognitive impairment (nci), mild cognitive impairment (mci), and ad. |
2023-03-29 |
2023-08-14 |
human |
| Somayeh Hajipour, Maryam Khombi Shooshtari, Yaghoob Farbood, Seyed Ali Mard, Alireza Sarkaki, Homeira Moradi Chameh, Neda Sistani Karampour, Samireh Ghafour. Fingolimod administration following hypoxia induced neonatal seizure can restore impaired long-term potentiation and memory performance in adult rats. Neuroscience. 2023-03-29. PMID:36990271. |
long-term potentiation (ltp) was recorded from hippocampal dentate gyrus region (dg) following stimulation of perforant pathway (pp). |
2023-03-29 |
2023-08-14 |
rat |
| Zongyue Sun, Meiqin Wang, Lei Xu, Qiongyu Li, Zhongyi Zhao, Xuehao Liu, Fantao Meng, Jing Liu, Wentao Wang, Chen Li, Shujun Jian. PPARγ/Adiponectin axis attenuates methamphetamine-induced conditional place preference via the hippocampal AdipoR1 signaling pathway. Progress in neuro-psychopharmacology & biological psychiatry. 2023-03-27. PMID:36972780. |
the meth induced adult male c57/bl6j mice model were used for testing the therapeutic activities of intraperitoneal injection of adiporon or rosiglitazone, and adipor1 overexpression in hippocampal dentate gyrus (dg), and chemogenetic inhibiting the neural activity of dg, and the changes of neurotrophic factors, synaptic molecules, and glutamate receptors, and inflammatory cytokines were also measured. |
2023-03-27 |
2023-08-14 |
mouse |
| Zongyue Sun, Meiqin Wang, Lei Xu, Qiongyu Li, Zhongyi Zhao, Xuehao Liu, Fantao Meng, Jing Liu, Wentao Wang, Chen Li, Shujun Jian. PPARγ/Adiponectin axis attenuates methamphetamine-induced conditional place preference via the hippocampal AdipoR1 signaling pathway. Progress in neuro-psychopharmacology & biological psychiatry. 2023-03-27. PMID:36972780. |
the observed inhibitory neural activity of the hippocampal dentate gyrus (dg) induced via a chemogenetic approach produced a therapeutic effect on the meth-induced cpp behavior. |
2023-03-27 |
2023-08-14 |
mouse |
| Yujeong Lee, Hee Ra Park, Joo Yeon Lee, Jaehoon Kim, Seonguk Yang, Chany Lee, Kipom Kim, Hyung Sik Kim, Seung-Cheol Chang, Jaewon Le. Low-dose curcumin enhances hippocampal neurogenesis and memory retention in young mice. Archives of pharmacal research. 2023-03-22. PMID:36947339. |
adult neurogenesis generates new functional neurons from adult neural stem cells in various regions, including the subventricular zone (svz) of the lateral ventricles and subgranular zone (sgz) of hippocampal dentate gyrus (dg). |
2023-03-22 |
2023-08-14 |
mouse |
| Liana Shvachiy, Ângela Amaro-Leal, Tiago F Outeiro, Isabel Rocha, Vera Geralde. Intermittent Lead Exposure Induces Behavioral and Cardiovascular Alterations Associated with Neuroinflammation. Cells. vol 12. issue 5. 2023-03-11. PMID:36899953. |
the expression of gfap, iba-1, neun and synaptophysin in the hippocampal dentate gyrus was assessed. |
2023-03-11 |
2023-08-14 |
rat |
| Rada Jeremic, Sanja Pekovic, Irena Lavrnja, Ivana Bjelobaba, Marina Djelic, Sanja Dacic, Predrag Brki. Hyperbaric Oxygenation Prevents Loss of Immature Neurons in the Adult Hippocampal Dentate Gyrus Following Brain Injury. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36901691. |
since the role of nscs in recovery from brain injury is still unclear, the purpose of this study was to investigate the effects of sensorimotor cortex ablation (sca) and hbo treatment (hbot) on the processes of neurogenesis in the adult dentate gyrus (dg), a region of the hippocampus that is the site of adult neurogenesis. |
2023-03-11 |
2023-08-14 |
rat |