| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yifan Wang, Qin Hong, Yueyue Xia, Zhao Zhang, Bo We. The Lysine Demethylase KDM7A Regulates Immediate Early Genes in Neurons. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-08-11. PMID:37565374. |
furthermore, in vivo knockdown of kdm7a in dentate gyrus (dg) neuron of mice hippocampus, via adeno-associated virus (aav)-based stereotaxic microinjection, led to a significant decrease of the expression of c-fos, a marker of neuron activity. |
2023-08-11 |
2023-08-16 |
mouse |
| Sophia Vinci-Booher, Margaret L Schlichting, Alison R Preston, Franco Pestill. Development of human hippocampal subfield microstructure and relation to associative inference. Cerebral cortex (New York, N.Y. : 1991). 2023-08-09. PMID:37557916. |
while the subiculum (sub) displayed a linear relationship with age, the dentate gyrus (dg), cornu ammonis field 1 (ca1), and cornu ammonis subfields 2 and 3 (combined; ca2/3) displayed nonlinear trajectories that interacted with sex in ca2/3. |
2023-08-09 |
2023-08-16 |
human |
| Yu-Wen Hung, Guan-Ling Lu, Hwei-Hsien Chen, Hsiu-Hui Tung, Sheau-Ling Le. Gliptins normalize posttraumatic hippocampal neurogenesis and restore cognitive function after controlled cortical impact on sensorimotor cortex. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-08-06. PMID:37544280. |
adult neurogenesis in the hippocampal dentate gyrus (dg) serves critical functions in cognition but can be disrupted by brain injury and insult in serval forms. |
2023-08-06 |
2023-08-14 |
mouse |
| Pei-Pei Liu, Shi-Ping Lu, Xiao Li, Gang-Bin Tang, Xiao Liu, Shang-Kun Dai, Lin-Fei Jiao, Xi-Wen Lin, Xing-Guo Li, Baoyang Hu, Jianwei Jiao, Zhao-Qian Teng, Chun-Sheng Han, Chang-Mei Li. Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus. Cell death and differentiation. 2023-08-05. PMID:37543710. |
disruption of arid1a in mouse forebrain significantly decreases neural stem/progenitor cells (nspcs) proliferation and differentiation to neurons within the dentate gyrus (dg), increasing perinatal and postnatal apoptosis, leading to reduced hippocampus size. |
2023-08-05 |
2023-08-14 |
mouse |
| Elena A Filimonova, Anton A Pashkov, Galina I Moysak, Anastasia Y Tropynina, Svetlana Y Zhanaeva, Anna A Shvaikovskaya, Anna A Akopyan, Konstantin V Danilenko, Lyubomir I Aftanas, Maria A Tikhonova, Jamil A Rzae. Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy. Frontiers in neuroscience. vol 17. 2023-08-04. PMID:37539386. |
we found that hippocampal (but not serum) bdnf levels were negatively correlated with the contralateral volumes of the ca1 and ca4 subfields, presubiculum, subiculum, dentate gyrus, and molecular layer of the hippocampus. |
2023-08-04 |
2023-08-14 |
human |
| Joshua D Rieskamp, Ileanexis Rosado-Burgos, Jacob E Christofi, Eliza Ansar, Dalia Einstein, Ashley E Walters, Valentina Valentini, John P Bruno, Elizabeth D Kirb. Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal. iScience. vol 26. issue 7. 2023-08-03. PMID:37534178. |
within the adult mammalian dentate gyrus (dg) of the hippocampus, glutamate stimulates neural stem cell (nsc) self-renewing proliferation, providing a link between adult neurogenesis and local circuit activity. |
2023-08-03 |
2023-08-14 |
Not clear |
| Parisa Sadat Panahi, Sogol Esmaili, Mohadeseh Ghalandari-Shamami, Zahra Mousavi, Abbas Haghparas. Similar functional roles of the Orexin-1 and Orexin-2 receptors within the dentate gyrus area of the hippocampus in the stress-induced antinociceptive responses in the acute pain model in the rat. Physiology & behavior. 2023-08-03. PMID:37536620. |
some evidence indicates that the hippocampus's dentate gyrus (dg) potentially modulates pain and stress. |
2023-08-03 |
2023-08-14 |
rat |
| Daniel D Callow, Yash Kommula, Craig E L Stark, J Carson Smit. Acute cycling exercise and hippocampal subfield function and microstructure in healthy older adults. Hippocampus. 2023-08-01. PMID:37526119. |
aging is associated with deterioration in dentate gyrus (dg) and ca3, both crucial hippocampal subfields for age susceptible memory processes such as mnemonic discrimination (md). |
2023-08-01 |
2023-08-14 |
human |
| Evanthia A Makrygianni, George P Chrouso. Neural Progenitor Cells and the Hypothalamus. Cells. vol 12. issue 14. 2023-07-29. PMID:37508487. |
in the postnatal/adult brain, npcs are primarily located in the subventricular zone (svz) of the lateral ventricles (lvs) and subgranular zone (sgz) of the hippocampal dentate gyrus (dg). |
2023-07-29 |
2023-08-14 |
Not clear |
| Kelsey D McDermott, M Agustina Frechou, Jake T Jordan, Sunaina S Martin, J Tiago Gonçalve. Delayed formation of neural representations of space in aged mice. Aging cell. 2023-07-26. PMID:37491802. |
the hippocampal dentate gyrus (dg) is important for processing spatial information in the brain and is particularly vulnerable to aging, yet its sparse activity has led to difficulties in assessing changes in this area. |
2023-07-26 |
2023-08-14 |
mouse |
| Greer S Kirshenbaum, Chia-Yuan Chang, Maria Bompolaki, Victoria R Bradford, Joseph Bell, Stylianos Kosmidis, Rebecca M Shansky, Javier Orlandi, Lisa M Savage, Alexander Z Harris, E David Leonardo, Alex Dranovsk. Adult-born neurons maintain hippocampal cholinergic inputs and support working memory during aging. Molecular psychiatry. 2023-07-21. PMID:37479778. |
these deficits were accompanied by compensatory reorganization of cholinergic dentate gyrus inputs with increased cholinergic innervation to the ventral hippocampus and recruitment of ventrally projecting neurons by the dorsal projection. |
2023-07-21 |
2023-08-14 |
Not clear |
| Gleice K Silva-Cardoso, Willian Lazarini-Lopes, Eduardo Octaviano Primini, Jaime E Hallak, José A Crippa, Antônio W Zuardi, Norberto Garcia-Cairasco, Christie R A Leite-Paniss. Cannabidiol modulates chronic neuropathic pain aversion behavior by attenuation of neuroinflammation markers and neuronal activity in the corticolimbic circuit in male Wistar rats. Behavioural brain research. 2023-07-20. PMID:37474023. |
in cci animals, cbd was able to attenuate the increase in neuronal hyperactivity, measured by fosb protein expression, in the regions of the corticolimbic circuit: anterior cingulate cortex (acc), complex basolateral amygdala (bla), granular layer of the dentate gyrus (grdg), and dorsal hippocampus (dh) - adjacent to subiculum (ca1). |
2023-07-20 |
2023-08-14 |
rat |
| Monica Garcia-Durillo, Bruno G Frenguell. Antagonism of P2X7 receptors enhances lorazepam action in delaying seizure onset in an in vitro model of status epilepticus. Neuropharmacology. 2023-07-17. PMID:37459909. |
this study evaluated the effect of the selective p2x7r antagonist a740003 on acute seizures in the dentate gyrus (dg) of hippocampal brain slices, where p2x7rs are highly expressed, with a view to establishing its potential use as a therapy or adjunct with lorazepam (lzp) in refractory se. |
2023-07-17 |
2023-08-14 |
mouse |
| Si Sun, Yitong Xu, Ningxi Yu, Meifeng Zhang, Jinghui Wang, Dong Wan, Zhen Tian, Huifeng Zh. Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway. Molecular neurobiology. 2023-07-13. PMID:37439957. |
catalpol remarkably promoted angiogenesis, promoted proliferation and differentiation of neural stem cells (nscs) in the subventricular zone (svz), and prevented neuronal loss and astrocyte activation in the ischemic cortex or hippocampal dentate gyrus (dg) in vivo. |
2023-07-13 |
2023-08-14 |
rat |
| Nerina M Villalba, Catalina Madarnas, Julieta Bressano, Viviana Sanchez, Alicia Brusc. Perinatal ethanol exposure affects cell populations in adult dorsal hippocampal neurogenic niche. Neuroscience research. 2023-07-07. PMID:37419388. |
in the adult brain, neurogenesis takes place in the dentate gyrus (dg) of the hippocampus and in the subventricular zone. |
2023-07-07 |
2023-08-14 |
mouse |
| Saif A Alharthy, Torki A Zughaibi, Puneet Vij, Shams Tabrez, Majed N Almashjary, Sarah Alharthi, Turki Alamri, Badra S Alghamdi, Steve Harakeh, Sheren A Azhari, Reem M Farsi, Hanan S Althagafy, Emad H M Hassanei. Mirtazapine attenuated cadmium-induced neuronal intoxication by regulating Nrf2 and NF-κB/TLR4 signals. Toxicology mechanisms and methods. 2023-07-05. PMID:37403423. |
compared to cd control rats, mzp attenuated histological abrasions in the cerebral cortex and ca1 and ca3 regions of the hippocampus as well as the dentate gyrus. |
2023-07-05 |
2023-08-14 |
human |
| Rafael de Jesús Macias-Velez, Martha Catalina Rivera-Cervantes, Alejandra Guadalupe Marín-López, Justo Murguía-Castill. Intranasal erythropoietin protects granular cells and reduces astrogliosis in the dentate gyrus after ischemic damage, an effect associated with molecular changes in erythropoietin and its receptor. Neuroscience letters. 2023-07-01. PMID:37393008. |
within the hippocampus, the ca1 and dentate gyrus (dg) regions are considered the most and the least susceptible to damage by cerebral ischemia, respectively. |
2023-07-01 |
2023-08-14 |
Not clear |
| Milenna T van Dijk, Ardesheer Talati, Pratik Kashyap, Karan Desai, Nora Kelsall, Marc Gameroff, Natalie Aw, Eyal Abraham, Breda Cullen, Jiook Cha, Christoph Anacker, Myrna M Weissman, Jonathan Posne. Dentate Gyrus Microstructure is associated with Resilience after Exposure to Maternal Stress Across Two Human Cohorts. Biological psychiatry. 2023-07-01. PMID:37393047. |
rodent models implicate the dentate gyrus (dg) of the hippocampus in the effects of ms on offspring depressive-like behaviors, but mechanisms in humans remain unclear. |
2023-07-01 |
2023-08-14 |
human |
| Feng Zhang, Kijun Yoon, Nam-Shik Kim, Guo-Li Ming, Hongjun Son. Cell-autonomous and non-cell-autonomous roles of NKCC1 in regulating neural stem cell quiescence in the hippocampal dentate gyrus. Stem cell reports. 2023-06-30. PMID:37390823. |
how nscs in the dentate gyrus (dg) of the hippocampus acquire their quiescence during early postnatal stages and continuously maintain quiescence in adulthood is poorly understood. |
2023-06-30 |
2023-08-14 |
Not clear |
| Jie Xu, Bowen Zheng, Yanmei Ma, Xiaopeng Zhang, Jianhua Cheng, Jing Yang, Peng Li, Jianzhong Zhang, Li Jing, Fang X. PI3K-AKT-mTOR signaling pathway regulates autophagy of hippocampal neurons in diabetic rats with chronic unpredictable mild stress. Behavioural brain research. 2023-06-30. PMID:37390967. |
the number of pyknotic neurons at cornu ammonis 1 (ca1) and dentate gyrus (dg) of the hippocampus in t2dd was significantly increased compared with cums and t2dm groups. |
2023-06-30 |
2023-08-14 |
rat |