| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xi Chen, Qian-Qian Cui, Xiao-Hai Hu, Jian Ye, Zi-Cun Liu, Yuan-Xi Mei, Fang Wang, Zhuang-Li Hu, Jian-Guo Che. CD200 in dentate gyrus improves depressive-like behaviors of mice through enhancing hippocampal neurogenesis via alleviation of microglia hyperactivation. Journal of neuroinflammation. vol 20. issue 1. 2023-06-30. PMID:37391731. |
cd200 in dentate gyrus improves depressive-like behaviors of mice through enhancing hippocampal neurogenesis via alleviation of microglia hyperactivation. |
2023-06-30 |
2023-08-14 |
mouse |
| Katerina Segklia, Rebecca Matsas, Florentia Papastefanak. Brain Infection by Group B Streptococcus Induces Inflammation and Affects Neurogenesis in the Adult Mouse Hippocampus. Cells. vol 12. issue 12. 2023-06-28. PMID:37371040. |
experimental encephalitis elicited neurological deficits and death, induced inflammation, and affected neurogenesis in the dentate gyrus of the adult hippocampus by suppressing the proliferation of progenitor cells and the generation of newborn neurons. |
2023-06-28 |
2023-08-14 |
mouse |
| Hua Liu, Yang Du, Lian Lin Liu, Qing Shan Liu, Hehui Mao, Yong Chen. Anti-depression-like effect of Mogroside V is related to the inhibition of inflammatory and oxidative stress pathways. European journal of pharmacology. 2023-06-26. PMID:37364672. |
pathological changes in the hippocampal dentate gyrus and cortex regions were detected by immunofluorescence and western blotting was used to measure the protein expression of bdnf, trkb, tnf-α, and akt. |
2023-06-26 |
2023-08-14 |
Not clear |
| Rita Chaaya, Joel R Steele, Brian G Oliver, Hui Chen, Rita Machaalan. Effects of e-vapour and high-fat diet on the immunohistochemical staining of nicotinic acetylcholine receptors, apoptosis, microglia and astrocytes in the adult male mouse hippocampus. Journal of chemical neuroanatomy. 2023-06-21. PMID:37343645. |
this study, using a mouse model, investigated the effects of exposure to e-vapour (± nicotine) and hfd (43% fat) consumption, on the expression of nicotinic acetylcholine receptor (nachr) subunits α3, α4, α7 and β2, apoptosis markers caspase-3 and tunel, microglial marker iba-1, and astrocyte marker gfap, in hippocampal subregions of dentate gyrus (dg) and cornu ammonis (ca) 1-3. |
2023-06-21 |
2023-08-14 |
mouse |
| Sanghee Yun, Ivan Soler, Fionya H Tran, Harley A Haas, Raymon Shi, Grace L Bancroft, Maiko Suarez, Christopher R de Santis, Ryan P Reynolds, Amelia J Eisc. Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity. Frontiers in behavioral neuroscience. vol 17. 2023-06-16. PMID:37324519. |
in humans and mice, discrimination and adaptation rely on the integrity of the hippocampal dentate gyrus (dg) which receives glutamatergic input from the entorhinal cortex (ec), including the lateral ec (lec). |
2023-06-16 |
2023-08-14 |
mouse |
| Isabel M Alonso Bellido, Mercedes Posada-Pérez, Francisco Hernández-Rasco, Sandra Vázquez-Reyes, María Cabanillas, Antonio J Herrera, Sara Bachiller, Jesús Soldán-Hidalgo, Ana M Espinosa-Oliva, Bertrand Joseph, Rocío M de Pablos, José L Venero, Rocío Rui. Microglial Caspase-3 is essential for modulating hippocampal neurogenesis. Brain, behavior, and immunity. 2023-06-16. PMID:37327833. |
after the reduction of caspase-3 in microglia, mutant mice showed a reduction of microglia in the hippocampus, especially in the dentate gyrus region, a region inherently associated to neurogenesis. |
2023-06-16 |
2023-08-14 |
mouse |
| Guo Xiang, Xia Liu, Jiangong Wang, Shunshun Lu, Meng Yu, Yuhan Zhang, Bin Sun, Bin Huang, Xin-Yun Lu, Xingang Li, Di Zhan. Peroxisome proliferator-activated receptor-α activation facilitates contextual fear extinction and modulates intrinsic excitability of dentate gyrus neurons. Translational psychiatry. vol 13. issue 1. 2023-06-15. PMID:37322045. |
the dentate gyrus (dg) of the hippocampus encodes contextual information associated with fear, and cell activity in the dg is required for acquisition and extinction of contextual fear. |
2023-06-15 |
2023-08-14 |
mouse |
| Mia Borzello, Steve Ramirez, Alessandro Treves, Inah Lee, Helen Scharfman, Craig Stark, James J Knierim, Lara M Range. Assessments of dentate gyrus function: discoveries and debates. Nature reviews. Neuroscience. 2023-06-14. PMID:37316588. |
there has been considerable speculation regarding the function of the dentate gyrus (dg) - a subregion of the mammalian hippocampus - in learning and memory. |
2023-06-14 |
2023-08-14 |
Not clear |
| Jing Liu, Fantao Meng, Wentao Wang, Min Wu, Yu Zhang, Minghu Cui, Changyun Qiu, Fengai Hu, Di Zhao, Dan Wang, Cuilan Liu, Dunjiang Liu, Zhicheng Xu, Yameng Wang, Wei Li, Chen L. Medial prefrontal cortical PPM1F alters depression-related behaviors by modifying p300 activity via the AMPK signaling pathway. CNS neuroscience & therapeutics. 2023-06-13. PMID:37309288. |
protein phosphatase mg2+/mn2+-dependent 1f (ppm1f) is a serine/threonine phosphatase, and its dysfunction in depression in the hippocampal dentate gyrus has been previously identified. |
2023-06-13 |
2023-08-14 |
Not clear |
| Huimin Wei, Huimin Jiang, Yifan Zhou, Xuechun Xiao, Chen Zhou, Xunming J. Cerebral venous congestion alters brain metabolite profiles, impairing cognitive function. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2023-06-13. PMID:37309740. |
using cerebral venous congestion rat models, we found these rats exhibited decreased long-term potentiation (ltp) in the hippocampal dentate gyrus and impaired spatial learning and memory. |
2023-06-13 |
2023-08-14 |
rat |
| Chen-Meng Qiao, Wei Quan, Yu Zhou, Gu-Yu Niu, Hui Hong, Jian Wu, Li-Ping Zhao, Ting Li, Chun Cui, Wei-Jiang Zhao, Yan-Qin She. Orally Induced High Serum Level of Trimethylamine N-oxide Worsened Glial Reaction and Neuroinflammation on MPTP-Induced Acute Parkinson's Disease Model Mice. Molecular neurobiology. 2023-06-02. PMID:37266763. |
furthermore, immunofluorescence, elisa, and rt-qpcr results of the hippocampus also showed that high serum tmao significantly promoted the activation of microglia and astrocytes in the dentate gyrus, increased the levels of tnf-α and il-1β, and upregulated gene expression of m1 microglia-related markers (including cd16, cd32, and inos) and a2 astrocyte-related markers (including s100a10, ptx3, and emp1) in mrna levels. |
2023-06-02 |
2023-08-14 |
mouse |
| Virendra Tiwari, Akanksha Mishra, Sonu Singh, Shubha Shukl. Crosstalk between Adult Hippocampal Neurogenesis and Its Role in Alzheimer's Disease. ACS chemical neuroscience. 2023-06-01. PMID:37261380. |
neurogenesis in adult brain is associated with synaptic plasticity, learning, and memory in dentate gyrus (dg) of hippocampus and olfactory bulb. |
2023-06-01 |
2023-08-14 |
Not clear |
| Chuanfeng Tang, Qiaona Wang, Jingyan Shen, Congying Wang, Hong Ding, Shiyu Wen, Fan Yang, Ruiqing Jiao, Xingxin Wu, Jianmei Li, Lingdong Kon. Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression. Acta pharmaceutica Sinica. B. vol 13. issue 5. 2023-05-30. PMID:37250149. |
neurogenesis decline in hippocampal dentate gyrus (dg) participates in stress-induced depressive-like behaviors, but the underlying mechanism remains poorly understood. |
2023-05-30 |
2023-08-14 |
mouse |
| Spiro P Pantazatos, Todd Ogden, Nadine M Melhem, David A Brent, Mohammad Lesanpezeshki, Ainsley Burke, John G Keilp, Jeffrey M Miller, J John Man. Smaller cornu ammonis (CA3) as a potential risk factor for suicidal behavior in mood disorders. Journal of psychiatric research. vol 163. 2023-05-27. PMID:37244064. |
structural brain imaging and hippocampal substructure segmentation quantified cornu ammonis (ca1-4), dentate gyrus, and subiculum gray matter volumes in healthy volunteers (hv, n = 25) and three groups with one or more relatives reporting early-onset mood disorder and suicide attempt: 1. |
2023-05-27 |
2023-08-14 |
human |
| Chiara Criscuolo, Elissavet Chartampila, Stephen D Ginsberg, Helen E Scharfma. Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer's disease neuropathology in a mouse model. bioRxiv : the preprint server for biology. 2023-05-23. PMID:37214931. |
however, the location where hippocampal bdnf protein is most highly expressed, the mossy fiber (mf) axons of dentate gyrus (dg) granule cells (gcs), has been understudied, and never in controlled |
2023-05-23 |
2023-08-14 |
mouse |
| Michelle C Gulfo, Joseph J Lebowitz, Czarina Ramos, Dong-Woo Hwang, Kaoutsar Nasrallah, Pablo E Castill. Dopamine D2 receptors in mossy cells reduce excitatory transmission and are essential for hippocampal function. bioRxiv : the preprint server for biology. 2023-05-19. PMID:37205586. |
hilar mossy cells (mcs) are principal excitatory neurons of the dentate gyrus (dg) that play critical roles in hippocampal function and have been implicated in brain disorders such as anxiety and epilepsy. |
2023-05-19 |
2023-08-14 |
Not clear |
| Carmen Vivar, Ben Peterson, Alejandro Pinto, Emma Janke, Henriette van Praa. Running throughout middle-age keeps eNeuro. 2023-05-15. PMID:37188520. |
in rodents, running increases the number of adult-born neurons in the dentate gyrus (dg) of the hippocampus, in association with improved synaptic plasticity and memory function. |
2023-05-15 |
2023-08-14 |
mouse |
| Carlo Abbat. The Adult Neurogenesis Theory of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023-05-14. PMID:37182879. |
this scenario involves nscs in the subgranular zone of the hippocampal dentate gyrus in late-onset ad (load) and nscs in the ventricular-subventricular zone along the lateral ventricles in early-onset ad (eoad), including familial ad (fad). |
2023-05-14 |
2023-08-14 |
Not clear |
| Ricardo Gómez-Oliva, Sergio Martínez-Ortega, Isabel Atienza-Navarro, Samuel Domínguez-García, Carlos Bernal-Utrera, Noelia Geribaldi-Doldán, Cristina Verástegui, Abdellah Ezzanad, Rosario Hernández-Galán, Pedro Nunez-Abades, Monica Garcia-Alloza, Carmen Castr. Rescue of neurogenesis and age-associated cognitive decline in SAMP8 mouse: Role of transforming growth factor-alpha. Aging cell. 2023-05-13. PMID:37177826. |
neuropathological aging is associated with memory impairment and cognitive decline, affecting several brain areas including the neurogenic niche of the dentate gyrus of the hippocampus (dg). |
2023-05-13 |
2023-08-14 |
mouse |
| Lei Ye, Shu Shu, Junqiu Jia, Min Sun, Siyi Xu, Xinyu Bao, Huijie Bian, Yi Liu, Meijuan Zhang, Xiaolei Zhu, Feng Bai, Yun X. Absent in melanoma 2 mediates aging-related cognitive dysfunction by acting on complement-dependent microglial phagocytosis. Aging cell. 2023-05-13. PMID:37177836. |
pattern separation (ps) dysfunction is a type of cognitive impairment that presents early during the aging process, and this deficit has been attributed to structural and functional alterations in the dentate gyrus (dg) of the hippocampus. |
2023-05-13 |
2023-08-14 |
mouse |