| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Roya Homayouni, Kelsey L Canada, Samaah Saifullah, Da' Jonae Foster, Charlotte Thill, Naftali Raz, Ana M Daugherty, Noa Ofe. Age-related differences in hippocampal subfield volumes across the human lifespan: A meta-analysis. Hippocampus. 2023-10-26. PMID:37881160. |
it is comprised of cytoarchitectonically distinct subfields: dentate gyrus (dg), cornu ammonis sectors (ca) 1-4, and subiculum, each of which may be differentially susceptible to neurodevelopmental and neurodegenerative mechanisms. |
2023-10-26 |
2023-11-08 |
human |
| Shaoyi Fang, Zhibin Wu, Yali Guo, Wenjun Zhu, Chunmiao Wan, Naijun Yuan, Jianbei Chen, Wenzhi Hao, Xiaowei Mo, Xiaofang Guo, Lili Fan, Xiaojuan Li, Jiaxu Che. Roles of microglia in adult hippocampal neurogenesis in depression and their therapeutics. Frontiers in immunology. vol 14. 2023-10-26. PMID:37881439. |
adult hippocampal neurogenesis generates functional neurons from neural progenitor cells in the hippocampal dentate gyrus (dg) to complement and repair neurons and neural circuits, thus benefiting the treatment of depression. |
2023-10-26 |
2023-11-08 |
Not clear |
| Larissa Marcely Gomes Cassiano, Marina da Silva Oliveira, Karina Barbosa de Queiroz, Alice Muglia Thomaz da Silva Amancio, Anna Christina de Matos Salim, Gabriel da Rocha Fernandes, Cláudia Martins Carneiro, Roney Santos Coimbr. Uncovering the neuroprotective effect of vitamin B12 in pneumococcal meningitis: insights into its pleiotropic mode of action at the transcriptional level. Frontiers in immunology. vol 14. 2023-10-20. PMID:37854591. |
the interplay between bacterial virulence factors and the host innate immune response in pneumococcal meningitis (pm) can result in uncontrolled neuroinflammation, which is known to induce apoptotic death of progenitor cells and post-mitotic neurons in the hippocampal dentate gyrus, resulting in cognitive impairment. |
2023-10-20 |
2023-11-08 |
Not clear |
| Roya Homayouni, Ana M Daugherty, Qijing Yu, Naftali Raz, Noa Ofe. KIBRA single nucleotide polymorphism is associated with hippocampal subfield volumes and cognition across development. Brain structure & function. 2023-10-18. PMID:37853296. |
the hippocampus (hc) consists of cytoarchitectonically and functionally distinct subfields: dentate gyrus (dg), cornu ammonis (ca1-3), and subiculum. |
2023-10-18 |
2023-11-08 |
Not clear |
| Chenlu Zhu, Xiao Ren, Chen Liu, Yawei Liu, Yonggang Wan. Neural regeneration research. vol 19. issue 4. 2023-10-16. PMID:37843222. |
neurogenesis in the hippocampal dentate gyrus is likely to persist throughout life but declines with aging, especially in alzheimer's disease. |
2023-10-16 |
2023-11-08 |
mouse |
| Youngkwan Kim, Hyo Rim Ko, Inwoo Hwang, Jee-Yin Ah. ErbB3 binding protein 1 contributes to adult hippocampal neurogenesis by modulating Bmp4 and Ascl1 signaling. BMB reports. 2023-10-11. PMID:37817439. |
ebp1 leads to transcriptional repression of bmp4 and suppression of ascl1 promoter methylation in the dentate gyrus of the adult hippocampus reflecting an unusually high level of bmp4 and low ascl1 level in neurons of ebp1-deficient mice. |
2023-10-11 |
2023-10-15 |
mouse |
| Jiandong Yu, Vijayalakshmi Santhakuma. Electrical Coupling between Parvalbumin Basket Cells is Reduced after Experimental Status Epilepticus. bioRxiv : the preprint server for biology. 2023-10-09. PMID:37808695. |
using a pilocarpine induced status epilepticus (se) model of acquired temporal lobe epilepsy in rat, this study examined changes in electrical coupling between pv-ins in the hippocampal dentate gyrus one week after se. |
2023-10-09 |
2023-10-15 |
human |
| Yuk-Hoi Yiu, Christian Leibol. A theory of hippocampal theta correlations accounting for extrinsic and intrinsic sequences. eLife. vol 12. 2023-10-04. PMID:37792453. |
here, we propose a computational model of cornu ammonis 3 (ca3) and dentate gyrus (dg), where sensorimotor input drives the direction-dependent (extrinsic) theta sequences within ca3 reflecting the two-dimensional spatial topology, whereas the intrahippocampal ca3-dg projections concurrently produce intrinsic sequences that are independent of the specific running trajectory. |
2023-10-04 |
2023-10-07 |
Not clear |
| Carmela Belardo, Serena Boccella, Michela Perrone, Antimo Fusco, Andrea Maria Morace, Federica Ricciardi, Roozbe Bonsale, Ines ELBini-Dhouib, Francesca Guida, Livio Luongo, Giacinto Bagetta, Damiana Scuteri, Sabatino Maion. Scopolamine-Induced Memory Impairment in Mice: Effects of PEA-OXA on Memory Retrieval and Hippocampal LTP. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37762702. |
these changes were associated with a loss of synaptic plasticity in the hippocampal dentate gyrus: impaired ltp after lateral entorhinal cortex/perforant pathway tetanization. |
2023-09-28 |
2023-10-07 |
mouse |
| Gabriel Berdugo-Vega, Shonali Dhingra, Federico Calegar. Sharpening the blades of the dentate gyrus: how adult-born neurons differentially modulate diverse aspects of hippocampal learning and memory. The EMBO journal. 2023-09-25. PMID:37743770. |
sharpening the blades of the dentate gyrus: how adult-born neurons differentially modulate diverse aspects of hippocampal learning and memory. |
2023-09-25 |
2023-10-07 |
Not clear |
| Mikhail Stepanichev, Victor Aniol, Natalia Lazareva, Natalia Gulyaev. Decreased Hippocampal Neurogenesis in Aged Male Wistar Rats Is Not Associated with Memory Acquisition in a Water Maze. International journal of molecular sciences. vol 24. issue 17. 2023-09-09. PMID:37686083. |
this brain region is essential for learning and memory, and the lifelong neurogenesis occurring in the subgranular zone of the dentate gyrus may be a key event mediating the mnemonic functions of the hippocampus. |
2023-09-09 |
2023-10-07 |
rat |
| Mingxie Ni, Meng Zheng, Bingran Chen, Xu Lu, Hui Zhao, Tao Zhu, Li Cheng, Han Han, Ting Ye, Huijun Liu, Ying Ye, Chao Huang, Xiaomei Yua. Microglial stimulation triggered by intranasal lipopolysaccharide administration produces antidepressant-like effect through ERK1/2-mediated BDNF synthesis in the hippocampus. Neuropharmacology. 2023-09-07. PMID:37678448. |
we recently reported that reversing the chronic stress-induced decline of microglia in the dentate gyrus (dg) of the hippocampus by intraperitoneal injection of a low dose of lipopolysaccharide (lps) ameliorated depression-like behavior in chronically stressed mice. |
2023-09-07 |
2023-10-07 |
mouse |
| Sumire Matsuura, Yuki Nishimoto, Akane Endo, Hirono Shiraki, Kanzo Suzuki, Eri Segi-Nishid. Hippocampal Inflammation and Gene Expression Changes in Peripheral Lipopolysaccharide Challenged Mice Showing Sickness and Anxiety-Like Behaviors. Biological & pharmaceutical bulletin. vol 46. issue 9. 2023-09-04. PMID:37661396. |
the aim of this study was to clarify temporal changes in the neuroinflammatory responses in the hippocampus and the response of dentate gyrus (dg) neurons using peripheral lipopolysaccharide (lps)-challenged mice. |
2023-09-04 |
2023-09-07 |
mouse |
| Satoshi Deyam. [Elucidation of the Mechanisms Underlying the Rapid Antidepressant Actions of Ketamine and Search for Possible Candidates for Novel Rapid-acting Antidepressants]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 143. issue 9. 2023-09-04. PMID:37661437. |
moreover, the intranasal administration of rve1 elicits rapid antidepressant-like effects through the release of bdnf and vegf in the mpfc and hippocampal dentate gyrus (dg), as well as mtorc1 activation in the mpfc, albeit not in the dg. |
2023-09-04 |
2023-09-07 |
human |
| Parvaneh Mohseni-Moghaddam, Hossein Khaleghzadeh-Ahangar, Rabi Atabak. Role of Necroptosis, a Regulated Cell Death, in Seizure and Epilepsy. Neurochemical research. 2023-08-30. PMID:37646959. |
these responses involve the activation of neurons and astrocytes, consequently leading to an increase in the expression levels of proteins and genes such as rip1, rip3, and mlkl in a time-dependent manner in regions such as the hippocampus (ca1, ca3, dentate gyrus, and hilus), piriform cortex, and amygdala. |
2023-08-30 |
2023-09-07 |
Not clear |
| Seyed Mehdi Vatandoust, Javad Mahmoudi, Shahrbanoo Oryan, Fereshteh Farajdokht, Saeed Sadigh-Eteghad, Siamak Sandoghchian Shotorbani, Huaxi Xu, Delaram Eslimi Esfahan. Sericin improves memory and sociability impairments evoked by transient global cerebral ischemia through suppression of hippocampal oxidative stress, inflammation, and apoptosis. The Chinese journal of physiology. vol 66. issue 4. 2023-08-28. PMID:37635480. |
notably, ser decreased neuronal apoptotic cell death in the hippocampal dentate gyrus (dg) region, accompanied by suppression of neuroinflammation, downregulation of pro-apoptotic proteins (caspase-9, caspases-3, and bax), and upregulation of anti-apoptotic protein, bcl-2. |
2023-08-28 |
2023-09-07 |
mouse |
| Grace Minogue, Allegra Kawles, Antonia Zouridakis, Rachel Keszycki, Alyssa Macomber, Vivienne Lubbat, Nathan Gill, Qinwen Mao, Margaret E Flanagan, Hui Zhang, Rudolph Castellani, Eileen H Bigio, M-Marsel Mesulam, Changiz Geula, Tamar Gefe. Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with TDP-43. Annals of neurology. 2023-08-18. PMID:37592884. |
here, we investigated neuronal integrity and pathologic burden of tdp-43 and tau along the well-charted trisynaptic hippocampal circuit [dentate gyrus (dg), ca3, and ca1] in participants with amnestic dementia due to ad/tdp, amnestic dementia due to ad alone, or non-amnestic dementia due to tdp-43 proteinopathy associated with frontotemporal lobar degeneration (ftld-tdp). |
2023-08-18 |
2023-09-07 |
human |
| Deep R Sharma, Bokun Cheng, Rauhin Sahu, Xusheng Zhang, Rana Mehdizadeh, Divya Singh, Dumitru Iacobas, Praveen Ballab. Oestrogen treatment restores dentate gyrus development in premature newborns by IGF1 regulation. Journal of cellular and molecular medicine. 2023-08-18. PMID:37594177. |
prematurity diminishes neurogenesis and synaptogenesis in the hippocampal dentate gyrus (dg). |
2023-08-18 |
2023-09-07 |
rabbit |
| . Expression of Concern: Stimulation of the Sigma-1 Receptor by DHEA Enhances Synaptic Efficacy and Neurogenesis in the Hippocampal Dentate Gyrus of Olfactory Bulbectomized Mice. PloS one. vol 18. issue 8. 2023-08-15. PMID:37582118. |
expression of concern: stimulation of the sigma-1 receptor by dhea enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice. |
2023-08-15 |
2023-09-07 |
mouse |
| Nanami Kasakura, Yuka Murata, Asuka Shindo, Shiho Kitaoka, Tomoyuki Furuyashiki, Kanzo Suzuki, Eri Segi-Nishid. Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process. Frontiers in neuroscience. vol 17. 2023-08-14. PMID:37575306. |
the dentate gyrus (dg) of the hippocampus regulates stress-related emotional behaviors and ensures neurogenesis throughout life. |
2023-08-14 |
2023-08-16 |
Not clear |