| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S V McLennan, D J Kelly, A J Cox, Z Cao, J G Lyons, D K Yue, R E Gilber. Decreased matrix degradation in diabetic nephropathy: effects of ACE inhibition on the expression and activities of matrix metalloproteinases. Diabetologia. vol 45. issue 2. 2002-07-31. PMID:11935159. |
decreased matrix degradation in diabetic nephropathy: effects of ace inhibition on the expression and activities of matrix metalloproteinases. |
2002-07-31 |
2023-08-12 |
Not clear |
| Edward T Parkin, Alison Trew, Gary Christie, Andrew Faller, Ruth Mayer, Anthony J Turner, Nigel M Hoope. Structure-activity relationship of hydroxamate-based inhibitors on the secretases that cleave the amyloid precursor protein, angiotensin converting enzyme, CD23, and pro-tumor necrosis factor-alpha. Biochemistry. vol 41. issue 15. 2002-05-17. PMID:11939793. |
compounds have been identified that can discriminate between tnf-alpha convertase and the other three secretases (compound 15), between the shedding of cd23 and the shedding of app and ace (compound 21), and between the secretases and matrix metalloproteinase-1 (compound 22). |
2002-05-17 |
2023-08-12 |
human |
| Z Cao, M E Coope. Role of angiotensin II in tubulointerstitial injury. Seminars in nephrology. vol 21. issue 6. 2001-12-21. PMID:11709803. |
blockade of production of angiotensin ii by an angiotensin-converting enzyme (ace) inhibitor or angiotensin ii receptor antagonism with an angiotensin type 1 receptor antagonist has been shown to attenuate tubulointerstitial injury and reduce expression of cytokines and matrix proteins. |
2001-12-21 |
2023-08-12 |
Not clear |
| S R Nallapareddy, K V Singh, R W Duh, G M Weinstock, B E Murra. Diversity of ace, a gene encoding a microbial surface component recognizing adhesive matrix molecules, from different strains of Enterococcus faecalis and evidence for production of ace during human infections. Infection and immunity. vol 68. issue 9. 2000-09-08. PMID:10948146. |
diversity of ace, a gene encoding a microbial surface component recognizing adhesive matrix molecules, from different strains of enterococcus faecalis and evidence for production of ace during human infections. |
2000-09-08 |
2023-08-12 |
human |
| S R Nallapareddy, K V Singh, R W Duh, G M Weinstock, B E Murra. Diversity of ace, a gene encoding a microbial surface component recognizing adhesive matrix molecules, from different strains of Enterococcus faecalis and evidence for production of ace during human infections. Infection and immunity. vol 68. issue 9. 2000-09-08. PMID:10948146. |
our previous work reported that most enterococcus faecalis strains adhered to the extracellular matrix proteins collagen types i and iv and laminin after growth at 46 degrees c, but not 37 degrees c, and we subsequently identified an e. faecalis sequence, ace, that encodes a bacterial adhesin similar to the collagen binding protein cna of staphylococcus aureus. |
2000-09-08 |
2023-08-12 |
human |
| S R Nallapareddy, K V Singh, R W Duh, G M Weinstock, B E Murra. Diversity of ace, a gene encoding a microbial surface component recognizing adhesive matrix molecules, from different strains of Enterococcus faecalis and evidence for production of ace during human infections. Infection and immunity. vol 68. issue 9. 2000-09-08. PMID:10948146. |
in conclusion, these results show that ace is highly conserved among isolates of e. faecalis, with at least four variants related to the differences in the b domain, is expressed by different strains during infection in humans, and human-derived antibodies can block adherence to these extracellular matrix proteins. |
2000-09-08 |
2023-08-12 |
human |
| S R Nallapareddy, X Qin, G M Weinstock, M Höök, B E Murra. Enterococcus faecalis adhesin, ace, mediates attachment to extracellular matrix proteins collagen type IV and laminin as well as collagen type I. Infection and immunity. vol 68. issue 9. 2000-09-08. PMID:10948147. |
enterococcus faecalis adhesin, ace, mediates attachment to extracellular matrix proteins collagen type iv and laminin as well as collagen type i. adhesin-mediated binding to extracellular matrix (ecm) proteins is thought to be a crucial step in the pathogenic process of many bacterial infections. |
2000-09-08 |
2023-08-12 |
Not clear |
| K M Ward-Cook, J D Mahan, C E Frenchko, A Albright, J M Chiasera, C McAlliste. Anionic charge sites in the kidney: comparison of two diabetic rat models. Annals of clinical and laboratory science. vol 29. issue 4. 1999-11-05. PMID:10528828. |
four obese zucker rats (zr) and four sprague-dawley rats were analyzed for the following parameters: number of acs per length of lamina rara externa (lre), (acs/lre); number of ace per length of lamina rara interna (lri) (acs/lri); percent of mesangial matrix as acs (%mmacs); percent of lre as acs (%lreacs); percent of lri as acs (%lriacs); length of acs in lri (lacslri); length of acs in lre (lacslre); width of acs in lri (wacslri); width of acs in the lre (wacslre); area of acs in the lri (aacslri); and the area of acs in the lre (aacslre). |
1999-11-05 |
2023-08-12 |
rat |
| S V Grinshtein, I I Nikolskaya, N L Klyachko, A V Levashov, O A Kos. Structural organization of membrane and soluble forms of somatic angiotensin-converting enzyme. Biochemistry. Biokhimiia. vol 64. issue 5. 1999-08-09. PMID:10381620. |
the ace activity strongly depends on the medium; it is higher when ace is in contact with matrix or other enzyme molecules. |
1999-08-09 |
2023-08-12 |
Not clear |
| H Kimura, F Gejyo, Y Suzuki, S Suzuki, R Miyazaki, M Arakaw. Polymorphisms of angiotensin converting enzyme and plasminogen activator inhibitor-1 genes in diabetes and macroangiopathy1. Kidney international. vol 54. issue 5. 1999-02-11. PMID:9844142. |
in smooth muscle cells and mesangial cells, the angiotensin ii synthesized by ace increases mrna expression and the activity of pai-1, which promotes antifibrinolysis and the accumulation of extracellular matrix. |
1999-02-11 |
2023-08-12 |
Not clear |
| S Mizuno, Y Horikawa, M Okamoto, T Kurosaw. Preventive effect of ACE inhibitor on interstitial myofibroblast formation and matrix deposition in a nephrotic model. Renal failure. vol 20. issue 3. 1998-08-25. PMID:9606736. |
preventive effect of ace inhibitor on interstitial myofibroblast formation and matrix deposition in a nephrotic model. |
1998-08-25 |
2023-08-12 |
mouse |
| K H Yoo, J T Wolstenholme, R L Chevalie. Angiotensin-converting enzyme inhibition decreases growth factor expression in the neonatal rat kidney. Pediatric research. vol 42. issue 5. 1997-12-09. PMID:9357928. |
this study was designed to investigate the effects of ace inhibition in the neonatal rat on the expression of genes known to modulate renal cellular proliferation, cell interactions, and extracellular matrix. |
1997-12-09 |
2023-08-12 |
rat |
| S Parvathy, S Y Oppong, E H Karran, D R Buckle, A J Turner, N M Hoope. Angiotensin-converting enzyme secretase is inhibited by zinc metalloprotease inhibitors and requires its substrate to be inserted in a lipid bilayer. The Biochemical journal. vol 327 ( Pt 1). 1997-12-02. PMID:9355732. |
several other non-hydroxamate-based collagenase inhibitors were without inhibitory effect on the secretase, indicating that ace secretase is a novel zinc metalloprotease that is realted to, but distinct from, the matrix metalloproteases. |
1997-12-02 |
2023-08-12 |
Not clear |
| N Makino, M Sugano, S Otsuka, T Hat. Molecular mechanism of angiotensin II type I and type II receptors in cardiac hypertrophy of spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). vol 30. issue 4. 1997-11-13. PMID:9336375. |
these results indicate that at1 receptor and ace, but not at2 receptor, play a crucial role in the remodeling of matrix tissue but a smaller role in the development of the hypertrophy of lv myocyte in shr and that the lv/body weight changes do not fully account for the complete suppression of hypertension. |
1997-11-13 |
2023-08-12 |
rat |
| H Geiger, W Fierlbeck, M Mai, H Ruchti, V Schönfeld, J Dämmrich, C Hugo, H H Neumaye. Effects of early and late antihypertensive treatment on extracellular matrix proteins and mononuclear cells in uninephrectomized SHR. Kidney international. vol 51. issue 3. 1997-06-04. PMID:9067907. |
they suggest that both ace inhibition and angiotensin ii blockade decrease renal cell proliferation and suppress the infiltration of mononuclear cells that may trigger expression of extracellular matrix proteins and progressive nephrosclerosis. |
1997-06-04 |
2023-08-12 |
rat |
| J Sesin, J Tamarg. [Effect of cilazapril, a converting enzyme inhibitor, on cardiovascular hypertrophy in the hypertensive patient]. Medicina. vol 56. issue 1. 1996-12-10. PMID:8734937. |
therefore, the renin-angiotensin system plays an important role in growth regulation and myocyte remodelation and in the cardiovascular extracellular matrix which is mediated through specific receptors, since it can be inhibited by ati receptor antagonists for angiotensin ii and ace. |
1996-12-10 |
2023-08-12 |
Not clear |
| Y Sun, K T Webe. Angiotensin converting enzyme and myofibroblasts during tissue repair in the rat heart. Journal of molecular and cellular cardiology. vol 28. issue 5. 1996-12-05. PMID:8762025. |
these findings suggest that myofibroblast ace may play a role in the fibrogenic response of tissue repair in the rat myocardium by regulating local concentrations of substances involved in healing and matrix remodeling. |
1996-12-05 |
2023-08-12 |
rat |
| K T Weber, Y Sun, L C Katw. Wound healing following myocardial infarction. Clinical cardiology. vol 19. issue 6. 1996-11-19. PMID:8790947. |
angiotensin-converting enzyme (ace) is expressed by wound-healing fibroblast-like cells; it likely serves to regulate local concentrations of angiotensin ii and bradykinin involved in healing and matrix remodeling. |
1996-11-19 |
2023-08-12 |
human |
| J J Morrissey, S Ishidoya, R McCracken, S Klah. The effect of ACE inhibitors on the expression of matrix genes and the role of p53 and p21 (WAF1) in experimental renal fibrosis. Kidney international. Supplement. vol 54. 1996-10-25. PMID:8731201. |
the effect of ace inhibitors on the expression of matrix genes and the role of p53 and p21 (waf1) in experimental renal fibrosis. |
1996-10-25 |
2023-08-12 |
rat |
| K Masutomo, N Makino, T Maruyama, T Shimada, T Yanag. Effects of enalapril on the collagen matrix in cardiomyopathic Syrian hamsters (Bio 14.6 and 53.58). Japanese circulation journal. vol 60. issue 1. 1996-07-19. PMID:8648884. |
we attempted to determine whether an angiotensin converting enzyme (ace) inhibitor, enalapril, prevents the increase in extracellular collagen matrix which connects the myocytes in cardiomyopathy. |
1996-07-19 |
2023-08-12 |
Not clear |