| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alain Beliveau, Joni D Mott, Alvin Lo, Emily I Chen, Antonius A Koller, Paul Yaswen, John Muschler, Mina J Bissel. Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo. Genes & development. vol 24. issue 24. 2011-02-18. PMID:21159820. |
these findings underscore the importance of the dynamic reciprocity between the extracellular matrix integrity, tissue polarity, and raf/mek/erk and mmp9 activities, providing an axis for either tissue homeostasis or malignant progression. |
2011-02-18 |
2023-08-12 |
human |
| Benoit Barrette, Ezéquiel Calvo, Nicolas Vallières, Steve Lacroi. Transcriptional profiling of the injured sciatic nerve of mice carrying the Wld(S) mutant gene: identification of genes involved in neuroprotection, neuroinflammation, and nerve regeneration. Brain, behavior, and immunity. vol 24. issue 8. 2011-01-21. PMID:20688153. |
the injured sciatic nerve of wt could be further distinguished from the one of wld(s) mice by the preferential upregulation of genes involved in axonal processes and plasticity (chl1, epha5, gadd45b, jun, nav2, nptx1, nrcam, ntm, sema4f), inflammation and immunity (arg1, lgals3, megf10, panx1), growth factors/cytokines and their receptors (clcf1, fgf5, gdnf, gfrα1, il7r, lif, ngfr/p75(ntr), shh), and cell adhesion and extracellular matrix (adam8, gpc1, mmp9, tnc). |
2011-01-21 |
2023-08-12 |
mouse |
| Annica Hedberg, Silje Fismen, Kristin A Fenton, Elin S Mortensen, Ole P Rekvi. Deposition of chromatin-IgG complexes in skin of nephritic MRL-lpr/lpr mice is associated with increased local matrix metalloprotease activities. Experimental dermatology. vol 19. issue 8. 2011-01-06. PMID:20500770. |
variations in matrix metalloprotease 2 (mmp2), mmp9 and dnase1 mrna levels and enzymatic activities were correlated with circulatory chromatin-igg complexes and deposition in skin. |
2011-01-06 |
2023-08-12 |
mouse |
| Siddika Selva Sume, Alpdogan Kantarci, Alan Lee, Hatice Hasturk, Philip C Trackma. Epithelial to mesenchymal transition in gingival overgrowth. The American journal of pathology. vol 177. issue 1. 2010-12-06. PMID:20489142. |
moreover, tgf-beta1 altered the expression of other markers of emt determined at the mrna and protein levels: e-cadherin decreased, whereas slug, fibronectin, matrix metalloproteinase (mmp)2, mmp9, and mmp13 increased. |
2010-12-06 |
2023-08-12 |
human |
| Wei Li, Han Li, Alan D Bocking, John R G Challi. Tumor necrosis factor stimulates matrix metalloproteinase 9 secretion from cultured human chorionic trophoblast cells through TNF receptor 1 signaling to IKBKB-NFKB and MAPK1/3 pathway. Biology of reproduction. vol 83. issue 3. 2010-11-30. PMID:20463356. |
in this study, we examine which signaling pathways are involved in tumor necrosis factor (tnf)-induced matrix metalloproteinase 9 (mmp9) secretion in human chorionic trophoblast (ct) cells. |
2010-11-30 |
2023-08-12 |
human |
| Florian Thilo, Ying Liu, Nico Schulz, Ulrich Gergs, Joachim Neumann, Christoph Loddenkemper, Maik Gollasch, Martin Tepe. Increased transient receptor potential vanilloid type 1 (TRPV1) channel expression in hypertrophic heart. Biochemical and biophysical research communications. vol 401. issue 1. 2010-11-30. PMID:20833132. |
transcripts of trpv1, matrix metalloproteinase 9 (mmp9), discoidin domain receptor family, member 2 (ddr-2), atrial natriuretic peptide (anp), gata 4, and regulatory microrna (mir-21) were analyzed using quantitative real-time pcr. |
2010-11-30 |
2023-08-12 |
mouse |
| Alexandra C Schrimpe, David W Wrigh. Comparative analysis of gene expression changes mediated by individual constituents of hemozoin. Chemical research in toxicology. vol 22. issue 3. 2010-11-23. PMID:19191707. |
hne exposure led to several significant steady-state expression changes including repressed chemokine (c-c motif) ligand 5 (ccl5), indicative of dyserythropoiesis, and a severe matrix metalloproteinase 9 (mmp9)/tissue inhibitor of metalloproteinase 1 (timp1) imbalance in favor of ecm proteolysis. |
2010-11-23 |
2023-08-12 |
Not clear |
| M P Ponnusamy, I Lakshmanan, M Jain, S Das, S Chakraborty, P Dey, S K Batr. MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells. Oncogene. vol 29. issue 42. 2010-11-09. PMID:20697346. |
knockdown of n-cadherin decreased the activation of extracellular signal-regulated kinase-1/2 (erk1/2), akt and matrix metalloproteinase 9 (mmp9), and inhibited the motility in the skov3-muc4 cells. |
2010-11-09 |
2023-08-12 |
human |
| Mi Young Ahn, Sang Duck Jee, Byung Mu Lee, Ji-Hye Yeon, Kun-Koo Park, Jae Sam Hwang, Eun Young Yu. Antidiabetic effects and gene expression profiling in obese mice treated with Isaria sinclairii over a 6-month period. Journal of toxicology and environmental health. Part A. vol 73. issue 21-22. 2010-11-05. PMID:20954077. |
in the case of sw, the enzymes (g2an, alpha glucosidase 2) and mmp9 (matrix metalloproteinase 9) involved in elevation of blood glucose levels were both downregulated. |
2010-11-05 |
2023-08-12 |
mouse |
| T Delessa Challa, Y Rais, E Monsonego Orna. Effect of adiponectin on ATDC5 proliferation, differentiation and signaling pathways. Molecular and cellular endocrinology. vol 323. issue 2. 2010-11-04. PMID:20380870. |
quantitative rt-pcr and gelatin zymography showed a significant increase in the matrix metalloproteinase mmp9's expression and activity following adiponectin treatment. |
2010-11-04 |
2023-08-12 |
mouse |
| Dimitris Stellas, Avraam El Hamidieh, Evangelia Patsavoud. Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits. BMC cell biology. vol 11. 2010-11-03. PMID:20602761. |
here we investigate the interaction of the secreted isoforms of hsp90 with matrix metalloproteinases (mmp) mmp2 and mmp9. |
2010-11-03 |
2023-08-12 |
human |
| Bo Peng, Lihuan Cao, Xiaopin Ma, Wenzhang Wang, Dan Wang, Long Y. Meta-analysis of association between matrix metalloproteinases 2, 7 and 9 promoter polymorphisms and cancer risk. Mutagenesis. vol 25. issue 4. 2010-10-21. PMID:20360147. |
matrix metalloproteinase (mmp) 2, mmp7 and mmp9 are important members of the mmp family. |
2010-10-21 |
2023-08-12 |
human |
| b' Delphine Benaitreau, Esther Dos Santos, Marie-Christine Leneveu, Nadia Alfaidy, Jean-Jacques Feige, Philippe de Mazancourt, Ren\\xc3\\xa9 Pecquery, Marie-No\\xc3\\xablle Dieudonn\\xc3\\xa. Effects of adiponectin on human trophoblast invasion. The Journal of endocrinology. vol 207. issue 1. 2010-10-12. PMID:20675305.' |
these pro-invasive effects of adiponectin in human trophoblasts seem to be mediated in part via increased matrix metalloproteinases (mmp2 and mmp9) activities and via repression of timp2 mrna expression. |
2010-10-12 |
2023-08-12 |
human |
| Lingling Yang, Huaqing Gong, Ye Wang, Yao Wang, Hongmei Yin, Peng Chen, Hongwei Zhang, Yiqiang Wan. Nicotine alters morphology and function of retinal pigment epithelial cells in mice. Toxicologic pathology. vol 38. issue 4. 2010-09-24. PMID:20448088. |
expression of matrix metalloproteinase protein (mmp)2, mmp9, and vegf was measured using western blot. |
2010-09-24 |
2023-08-12 |
mouse |
| Jongmin Kim, Seok Joo Hong, Jin Young Park, Jun Ho Park, Yun-Suk Yu, Sun Young Park, Eun Kyung Lim, Kwan Yong Choi, Eun Kyu Lee, Seung Sam Paik, Kyeong Geun Lee, Hee Jung Wang, In-Gu Do, Jae-Won Joh, Dae Shick Ki. Epithelial-mesenchymal transition gene signature to predict clinical outcome of hepatocellular carcinoma. Cancer science. vol 101. issue 6. 2010-09-14. PMID:20331628. |
from a univariate cox analysis for a training cohort of 128 hepatocellular carcinoma patients, four candidate genes (e-cadherin [cdh1], inhibitor of dna binding 2 [id2], matrix metalloproteinase 9 [mmp9], and transcription factor 3 [tcf3]) with significant prognostic values were selected to develop a risk score of patient survival. |
2010-09-14 |
2023-08-12 |
human |
| Hannah H Yan, Michael Pickup, Yanli Pang, Agnieszka E Gorska, Zhaoyang Li, Anna Chytil, Yipeng Geng, Jerome W Gray, Harold L Moses, Li Yan. Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. Cancer research. vol 70. issue 15. 2010-09-13. PMID:20631080. |
in addition, they produce large quantities of matrix metalloproteinase 9 (mmp9) and promote vascular remodeling. |
2010-09-13 |
2023-08-12 |
mouse |
| Takanori Kitamura, Teruaki Fujishita, Pius Loetscher, Laszlo Revesz, Hiroki Hashida, Shinae Kizaka-Kondoh, Masahiro Aoki, Makoto M Taket. Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 29. 2010-09-01. PMID:20616008. |
they express ccl9/15 receptor ccr1 and produce matrix metalloproteinases mmp2 and mmp9. |
2010-09-01 |
2023-08-12 |
mouse |
| Zhen Liu, Lixia Li, Zhixiong Yang, Weiren Luo, Xin Li, Huiling Yang, Kaitai Yao, Bin Wu, Weiyi Fan. Increased expression of MMP9 is correlated with poor prognosis of nasopharyngeal carcinoma. BMC cancer. vol 10. 2010-08-16. PMID:20534121. |
the aim of the present study was to analyze the expression of matrix metalloproteinase 9 (mmp9) in nasopharyngeal carcinoma (npc) and its correlation with clinicopathologic features, including the survival of patients with npc. |
2010-08-16 |
2023-08-12 |
Not clear |
| Lixin Yang, Nga Yu Ho, Ferenc Müller, Uwe Strähl. Methyl mercury suppresses the formation of the tail primordium in developing zebrafish embryos. Toxicological sciences : an official journal of the Society of Toxicology. vol 115. issue 2. 2010-08-10. PMID:20181659. |
the matrix metalloproteases mmp9 and mmp13 and eight other genes are induced in the embryonic tail in response to mehg. |
2010-08-10 |
2023-08-12 |
zebrafish |
| Hwa Jung Choi, Young Ran Park, Manoj Nepal, Bo-Yun Choi, Nam-Pyo Cho, Seoung Hwan Choi, Soo Rye Heo, Hyung Sup Kim, Moon-Sik Yang, Yunjo So. Inhibition of osteoclastogenic differentiation by Ikarisoside A in RAW 264.7 cells via JNK and NF-kappaB signaling pathways. European journal of pharmacology. vol 636. issue 1-3. 2010-08-09. PMID:20353769. |
the inhibitory effect of ikarisoside a resulted in decrease of osteoclast-specific genes like matrix metalloproteinase 9 (mmp9), tartrate-resistant acid phosphatase (trap), receptor activator of nf-kappab (rank), and cathepsin k. moreover, ikarisoside a blocked the resorbing capacity of raw 264.7 cells on calcium phosphate-coated plates. |
2010-08-09 |
2023-08-12 |
Not clear |