| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fei Han, Hong-Guang Zh. Caveolin-1 regulating the invasion and expression of matrix metalloproteinase (MMPs) in pancreatic carcinoma cells. The Journal of surgical research. vol 159. issue 1. 2010-03-23. PMID:20031158. |
the gelatinases b (mmp9) and a (mmp2) are two members of the matrix metalloproteinase (mmps) family that are expressed in human cancer, and play a critical role in tumor cell invasion and metastasis. |
2010-03-23 |
2023-08-12 |
human |
| Camila F Nascimento, Letícia N Gama-De-Souza, Vanessa M Freitas, Ruy G Jaege. Role of MMP9 on invadopodia formation in cells from adenoid cystic carcinoma. Study by laser scanning confocal microscopy. Microscopy research and technique. vol 73. issue 2. 2010-03-17. PMID:19658178. |
after 1 h in fluorescent substrate, cells with silenced mmp9 showed clear decrease in matrix digestion compared with controls. |
2010-03-17 |
2023-08-12 |
human |
| Zhi-jie He, Zi-tong Huang, Xiao-tong Chen, Zi-jun Zo. Effects of matrix metalloproteinase 9 inhibition on the blood brain barrier and inflammation in rats following cardiopulmonary resuscitation. Chinese medical journal. vol 122. issue 19. 2010-03-17. PMID:20079138. |
matrix metalloproteinases (mmps), especially mmp9 attracted much attention because of its function in focal brain ischemia/reperfusion injury. |
2010-03-17 |
2023-08-12 |
rat |
| Geraldine Gueron, Adriana De Siervi, Mercedes Ferrando, Marcelo Salierno, Paola De Luca, Belen Elguero, Roberto Meiss, Nora Navone, Elba S Vazque. Critical role of endogenous heme oxygenase 1 as a tuner of the invasive potential of prostate cancer cells. Molecular cancer research : MCR. vol 7. issue 11. 2010-03-04. PMID:19903769. |
using reverse transcription-quantitative pcr-generated gene array, a set of inflammatory and angiogenic genes were upregulated or downregulated in response to ho-1 overexpression identifying matrix metalloprotease 9 (mmp9) as a novel downstream target of ho-1. |
2010-03-04 |
2023-08-12 |
mouse |
| Silvia Barbaresi, Marc S Cortese, Jean Quinn, G Hossein Ashrafi, Sheila V Graham, M Saveria Camp. Effects of human papillomavirus type 16 E5 deletion mutants on epithelial morphology: functional characterization of each transmembrane domain. The Journal of general virology. vol 91. issue Pt 2. 2010-02-09. PMID:19812262. |
using deletion mutants which encompass the three hydrophobic domains of e5, we have assigned the ability to promote invasion of the matrix to the first hydrophobic domain, and the capacity to induce mmp9 to the c-terminal four amino acids. |
2010-02-09 |
2023-08-12 |
human |
| Hannah E Volkman, Tamara C Pozos, John Zheng, J Muse Davis, John F Rawls, Lalita Ramakrishna. Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium. Science (New York, N.Y.). vol 327. issue 5964. 2010-02-02. PMID:20007864. |
here, we identified the molecular mechanism by which mycobacteria induce granulomas: the bacterial secreted protein 6-kd early secreted antigenic target (esat-6), which has long been implicated in virulence, induced matrix metalloproteinase-9 (mmp9) in epithelial cells neighboring infected macrophages. |
2010-02-02 |
2023-08-12 |
zebrafish |
| Robert C Kaplan, Nicholas L Smith, Stanley Zucker, Susan R Heckbert, Kenneth Rice, Bruce M Psat. Matrix metalloproteinase-3 (MMP3) and MMP9 genes and risk of myocardial infarction, ischemic stroke, and hemorrhagic stroke. Atherosclerosis. vol 201. issue 1. 2010-01-26. PMID:18342317. |
matrix metalloproteinase-3 (mmp3) and mmp9 genes and risk of myocardial infarction, ischemic stroke, and hemorrhagic stroke. |
2010-01-26 |
2023-08-12 |
Not clear |
| Difei Shen, Qizhu Tang, Zhengrong Huang, Ying Chen, Ran Xiong, Hui Wu, Ji Huang, Siting Feng, Ling Yan, Zhouyan Bia. The effects of NK4 on viral myocarditis mice. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. vol 18. issue 6. 2010-01-08. PMID:19150247. |
the changes in mmp3 (matrix metalloproteinase 3), mmp9, timp1 (tissue inhibitor of metalloproteinase 1), and tgf (transforming growth factor)-beta1 expression in the myocardium were measured by reverse-transcriptase polymerase chain reaction. |
2010-01-08 |
2023-08-12 |
mouse |
| Thomas J Wilson, Kalyan C Nannuru, Rakesh K Sing. Cathepsin G-mediated activation of pro-matrix metalloproteinase 9 at the tumor-bone interface promotes transforming growth factor-beta signaling and bone destruction. Molecular cancer research : MCR. vol 7. issue 8. 2010-01-06. PMID:19671689. |
we hypothesized that the observed increase in tgf-beta signaling is due to increased cathepsin g-dependent, matrix metalloproteinase 9 (mmp9)-mediated activation of latent tgf-beta. |
2010-01-06 |
2023-08-12 |
Not clear |
| Adrian O'Hara, Fei-Ling Lim, Dawn J Mazzatti, Paul Trayhur. Microarray analysis identifies matrix metalloproteinases (MMPs) as key genes whose expression is up-regulated in human adipocytes by macrophage-conditioned medium. Pflugers Archiv : European journal of physiology. vol 458. issue 6. 2009-12-31. PMID:19585142. |
a cluster of matrix metalloproteinase genes were highly up-regulated at both time-points, including mmp1, mmp3, mmp9, mmp10, mmp12 and mmp19. |
2009-12-31 |
2023-08-12 |
human |
| Hoyee Leong, Priya S Mathur, Geoffrey L Green. Green tea catechins inhibit angiogenesis through suppression of STAT3 activation. Breast cancer research and treatment. vol 117. issue 3. 2009-12-16. PMID:18821062. |
we demonstrate that administration of polyphenon e (poly e), a standardized green tea extract, inhibited mda-mb231 breast cancer and human dermal microvascular endothelial (hmvec) cell migration and the expression of vascular endothelial growth factor (vegf) and matrix metalloproteinase 9 (mmp9). |
2009-12-16 |
2023-08-12 |
human |
| Weiwei Yu, Jinhui Liu, Xiaoliang Xiong, Yousheng Ai, Huamin Wan. Expression of MMP9 and CD147 in invasive squamous cell carcinoma of the uterine cervix and their implication. Pathology, research and practice. vol 205. issue 10. 2009-12-16. PMID:19541433. |
matrix metalloproteinase 9 (mmp9) and cd147 play a role in invasion and metastasis of many types of human malignancies. |
2009-12-16 |
2023-08-12 |
human |
| Kaori Tsutsumi, Masumi Tsuda, Natsuka Yazawa, Hirotaka Nakamura, Seiichiro Ishihara, Hisashi Haga, Motoaki Yasuda, Rie Yamazaki, Hiroki Shirato, Hideaki Kawaguchi, Takeshi Nishioka, Yusuke Ohb. Increased motility and invasiveness in tumor cells that survive 10 Gy irradiation. Cell structure and function. vol 34. issue 2. 2009-12-14. PMID:19724156. |
the mrna expression levels of matrix metalloproteinases (mmps), including mmp1, mmp2, and mmp9, were upregulated in ir cells compared with parental cells. |
2009-12-14 |
2023-08-12 |
human |
| Cristina de Carvalho Dornelles, Sady Selaimen da Costa, Luíse Meurer, Letícia Petersen Schmidt Rosito, Andrei Roberto da Silva, Sabrina Lima Alve. Comparison of acquired cholesteatoma between pediatric and adult patients. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 266. issue 10. 2009-12-11. PMID:19322578. |
samples of 120 cholesteatomas were fixed in 10% formol, prepared on five slides of each sample through habitual histological techniques, and number of blood vessels (cd31), marking with mmp2 and mmp9, number of matrix cells and thickness at perimatrix cell were observed. |
2009-12-11 |
2023-08-12 |
Not clear |
| Hitesh S Deshmukh, Anne McLachlan, Jeffrey J Atkinson, William D Hardie, Thomas R Korfhagen, Maggie Dietsch, Yang Liu, Peter Y P Di, Scott C Wesselkamper, Michael T Borchers, George D Leikau. Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production. American journal of respiratory and critical care medicine. vol 180. issue 9. 2009-12-01. PMID:19661247. |
previously, we reported that acrolein levels found in copd sputum could activate matrix metalloproteinase-9 (mmp9). |
2009-12-01 |
2023-08-12 |
Not clear |
| Yuji Nakamaru, Chaitanya Vuppusetty, Hiroo Wada, Jill C Milne, Misako Ito, Christos Rossios, Mark Elliot, James Hogg, Sergei Kharitonov, Hajime Goto, Jean E Bemis, Peter Elliott, Peter J Barnes, Kazuhiro It. A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 23. issue 9. 2009-10-23. PMID:19376817. |
inappropriate elevation of matrix metalloproteinase-9 (mmp9) is reported to be involved in the pathogenesis of chronic obstructive pulmonary disease (copd). |
2009-10-23 |
2023-08-12 |
mouse |
| D Y Yeh, H I Lin, N H Feng, C F Chen, D Wang, N T Wan. Matrix metalloprotease expressions in both reperfusion lung injury and oleic acid lung injury models and the protective effects of ilomastat. Transplantation proceedings. vol 41. issue 5. 2009-09-28. PMID:19545667. |
our aim was to study the expressions of matrix metalloprotease 9 (mmp9) and the effects of the mmp inhibitor ilomastat in both ischemia/reperfusion (i/r)- and oleic acid (oa)-induced lung injury models. |
2009-09-28 |
2023-08-12 |
Not clear |
| Ekkehart Lausch, Romy Keppler, Katja Hilbert, Valerie Cormier-Daire, Sarah Nikkel, Gen Nishimura, Sheila Unger, Jürgen Spranger, Andrea Superti-Furga, Bernhard Zabe. Mutations in MMP9 and MMP13 determine the mode of inheritance and the clinical spectrum of metaphyseal anadysplasia. American journal of human genetics. vol 85. issue 2. 2009-09-23. PMID:19615667. |
the matrix metalloproteinases mmp9 and mmp13 catalyze the degradation of extracellular matrix (ecm) components in the growth plate and at the same time cleave and release biologically active molecules stored in the ecm, such as vegfa. |
2009-09-23 |
2023-08-12 |
mouse |
| Zhi Li, Li-Juan Bian, Yang Li, Ying-Jie Liang, Hui-Zhen Lian. Expression of protease-activated receptor-2 (PAR-2) in patients with nasopharyngeal carcinoma: correlation with clinicopathological features and prognosis. Pathology, research and practice. vol 205. issue 8. 2009-09-22. PMID:19269113. |
we aimed at determining whether the expression of protease-activated receptor 2 (par-2) is involved in the progression of nasopharyngeal carcinoma (npc) and correlated with latent membrane protein 1 (lmp-1), matrix metalloproteinases-9 (mmp9), and angiogenesis of tumor. |
2009-09-22 |
2023-08-12 |
Not clear |
| Leila Jackson, Carol T Cady, John C Cambie. TLR4-mediated signaling induces MMP9-dependent cleavage of B cell surface CD23. Journal of immunology (Baltimore, Md. : 1950). vol 183. issue 4. 2009-09-09. PMID:19635918. |
lps also induced expression of matrix metalloprotease 9 (mmp9) and failed to induce cd23 cleaving activity in mmp9(-/-) cells, thus implicating mmp9 in the lps-induced release of cd23 from the cell surface. |
2009-09-09 |
2023-08-12 |
human |