| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong Dong Chen, Xun Xu, Xin Xia, Haixiang Wu, Kun Liu, Zhi Zheng, Dongqing Zh. MMP9 is involved in glycation end-products induced increase of retinal vascular permeability in rats and the therapeutic effect of minocycline. Current eye research. vol 33. issue 11. 2009-03-20. PMID:19085380. |
to determine the role of matrix metalloproteinase 9 (mmp9) in advanced glycation end-products (ages) induced damage to blood-retinal barrier (brb) and the therapeutic effects of minocycline, an mmp inhibitor, against the brb damages. |
2009-03-20 |
2023-08-12 |
rat |
| S Horstmann, J A Koziol, F Martinez-Torres, S Nagel, H Gardner, S Wagne. Sonographic monitoring of mass effect in stroke patients treated with hypothermia. Correlation with intracranial pressure and matrix metalloproteinase 2 and 9 expression. Journal of the neurological sciences. vol 276. issue 1-2. 2009-03-17. PMID:18834996. |
we also determined matrix metalloproteinase 2 (mmp2) and matrix metalloproteinase 9 (mmp9) in serum by zymography. |
2009-03-17 |
2023-08-12 |
Not clear |
| Zuzanna Szymańska, Jakub Urbański, Anna Marciniak-Czochr. Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue. Journal of mathematical biology. vol 58. issue 4-5. 2009-03-12. PMID:18807037. |
according to experimental data, inhibition of one of these proteins, hsp90, slows down cancer cells while they are invading tissue, but does not affect the synthesis of matrix metalloproteinases (mmp2 and mmp9), which are very important for cancer metastasis, acting as extracellular matrix (ecm) degrading enzymes. |
2009-03-12 |
2023-08-12 |
Not clear |
| Sue Wilson, Taina Taskila, Tariq Ismail, Deborah D Stocken, Ashley Martin, Val Redman, Michael Wakelam, Ian Perry, Richard Hobb. Establishing the added benefit of measuring MMP9 in FOB positive patients as a part of the Wolverhampton colorectal cancer screening programme. BMC cancer. vol 9. 2009-03-06. PMID:19175925. |
increased levels of an enzyme called matrix metalloproteinase 9 (mmp9) have been found to be associated with colorectal cancer, and this can be measured from a blood sample. |
2009-03-06 |
2023-08-12 |
Not clear |
| Magda Gioia, Susanna Monaco, Philippe E Van Den Steen, Diego Sbardella, Giuseppe Grasso, Stefano Marini, Christopher M Overall, Ghislain Opdenakker, Massimo Colett. The collagen binding domain of gelatinase A modulates degradation of collagen IV by gelatinase B. Journal of molecular biology. vol 386. issue 2. 2009-02-20. PMID:19109975. |
its remodeling is executed by a family of matrix metalloproteinases (mmps), of which the constitutive gelatinase a (mmp2) and the inducible gelatinase b (mmp9) are key examples. |
2009-02-20 |
2023-08-12 |
human |
| Fei Chen, Per Eriksson, Carl Whatling, Jarle Vaage, Guro Vale. Surgical handling of saphenous vein grafts induces expression of matrix metalloproteinase 9. Scandinavian cardiovascular journal : SCJ. vol 42. issue 5. 2009-01-22. PMID:18609045. |
to investigate whether human veins responded to surgical handling with acute remodelling by measuring matrix metalloproteinase 9 (mmp9) expression and activity. |
2009-01-22 |
2023-08-12 |
human |
| Warren B Nothnic. Regulation of uterine matrix metalloproteinase-9 and the role of microRNAs. Seminars in reproductive medicine. vol 26. issue 6. 2009-01-07. PMID:18951331. |
controlled expression of matrix metalloproteinase-9 (mmp9) is vital for normal uterine physiology, whereas abnormal expression of mmp9 is associated with uterine disease. |
2009-01-07 |
2023-08-12 |
Not clear |
| Anna M Wasilewska, Walentyna M Zoch-Zwier. Urinary levels of matrix metalloproteinases and their tissue inhibitors in nephrotic children. Pediatric nephrology (Berlin, Germany). vol 23. issue 10. 2008-11-18. PMID:18594870. |
the aim of this study was to determine the effects of cyclosporine a (cya) on urinary levels of matrix metalloproteinase 2 and 9 (mmp2, mmp9) and their tissue inhibitors 1 and 2 (timp1, timp2) in steroid-dependent nephrotic syndrome (sdns). |
2008-11-18 |
2023-08-12 |
human |
| Jin Xu, Na Li, De-Zai Dai, Feng Yu, Yin Da. The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH oxidase [correction of oxidas], ETA, ETB, and MMP9 in the vasculature. Journal of cardiovascular pharmacology. vol 52. issue 1. 2008-11-13. PMID:18594475. |
on day 11, we found an increase in vascular response to phenylephrine (phe) and reductions in no availability and acetylcholine (ach)-induced relaxation in iso-treated rats along with upregulated mrna of eta, etb, inos, nadph oxidase-phox22 and phox47, and matrix metalloproteinase 9 (mmp9). |
2008-11-13 |
2023-08-12 |
rat |
| Zhanguo Gao, Jianping Y. Inhibition of transcriptional activity of c-JUN by SIRT1. Biochemical and biophysical research communications. vol 376. issue 4. 2008-11-13. PMID:18823944. |
sirt1 was found in the ap-1 response element in the matrix metalloproteinase-9 (mmp9) promoter dna leading to inhibition of histone 3 acetylation as shown in a chip assay. |
2008-11-13 |
2023-08-12 |
mouse |
| Hiroshi Yagi, Fusanori Yotsumoto, Shingo Miyamot. Heparin-binding epidermal growth factor-like growth factor promotes transcoelomic metastasis in ovarian cancer through epithelial-mesenchymal transition. Molecular cancer therapeutics. vol 7. issue 10. 2008-11-12. PMID:18852147. |
crm197, an inhibitor of hb-egf, resulted in a significant decrease of tumor burden in peritoneal dissemination, accompanied with a reduction in both cellular spreading, when assayed on an extracellular matrix, and invasive ability, when assayed in a chemotaxis chamber, as well as decreased expression of mmp9 and vegf. |
2008-11-12 |
2023-08-12 |
Not clear |
| Yusuke Shinoda, Naoshi Ogata, Akiro Higashikawa, Ichiro Manabe, Takayuki Shindo, Takashi Yamada, Fumitaka Kugimiya, Toshiyuki Ikeda, Naohiro Kawamura, Yosuke Kawasaki, Kensuke Tsushima, Norifumi Takeda, Ryozo Nagai, Kazuto Hoshi, Kozo Nakamura, Ung-il Chung, Hiroshi Kawaguch. Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9. The Journal of biological chemistry. vol 283. issue 36. 2008-10-20. PMID:18617520. |
microarray analyses identified mmp9 (matrix metalloproteinase 9) as a transcriptional target, since it was strongly up-regulated by adenoviral transfection of klf5 in chondrogenic cell line oums27. |
2008-10-20 |
2023-08-12 |
mouse |
| Yusuke Shinoda, Naoshi Ogata, Akiro Higashikawa, Ichiro Manabe, Takayuki Shindo, Takashi Yamada, Fumitaka Kugimiya, Toshiyuki Ikeda, Naohiro Kawamura, Yosuke Kawasaki, Kensuke Tsushima, Norifumi Takeda, Ryozo Nagai, Kazuto Hoshi, Kozo Nakamura, Ung-il Chung, Hiroshi Kawaguch. Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9. The Journal of biological chemistry. vol 283. issue 36. 2008-10-20. PMID:18617520. |
mmp9 expression was decreased in the limbs of klf5+/- embryos, which was correlated with suppression of matrix degradation, calcification, and vascularization. |
2008-10-20 |
2023-08-12 |
mouse |
| Yusuke Shinoda, Naoshi Ogata, Akiro Higashikawa, Ichiro Manabe, Takayuki Shindo, Takashi Yamada, Fumitaka Kugimiya, Toshiyuki Ikeda, Naohiro Kawamura, Yosuke Kawasaki, Kensuke Tsushima, Norifumi Takeda, Ryozo Nagai, Kazuto Hoshi, Kozo Nakamura, Ung-il Chung, Hiroshi Kawaguch. Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9. The Journal of biological chemistry. vol 283. issue 36. 2008-10-20. PMID:18617520. |
we conclude that klf5 causes cartilage matrix degradation through transcriptional induction of mmp9, providing the first evidence that transcriptional regulation of a proteinase contributes to endochondral ossification and skeletal development. |
2008-10-20 |
2023-08-12 |
mouse |
| Li Qin, Lan Liao, Aisling Redmond, Leonie Young, Yuhui Yuan, Hongwu Chen, Bert W O'Malley, Jianming X. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Molecular and cellular biology. vol 28. issue 19. 2008-10-20. PMID:18644862. |
the aib1 oncogene promotes breast cancer metastasis by activation of pea3-mediated matrix metalloproteinase 2 (mmp2) and mmp9 expression. |
2008-10-20 |
2023-08-12 |
mouse |
| Li Qin, Lan Liao, Aisling Redmond, Leonie Young, Yuhui Yuan, Hongwu Chen, Bert W O'Malley, Jianming X. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Molecular and cellular biology. vol 28. issue 19. 2008-10-20. PMID:18644862. |
molecular analyses revealed that aib1 served as a pea3 coactivator and formed complexes with pea3 on matrix metalloproteinase 2 (mmp2) and mmp9 promoters to enhance their expression in both mouse and human breast cancer cells. |
2008-10-20 |
2023-08-12 |
mouse |
| Megumi Iiizumi, Sucharita Bandyopadhyay, Sudha K Pai, Misako Watabe, Shigeru Hirota, Sadahiro Hosobe, Taisei Tsukada, Kunio Miura, Ken Saito, Eiji Furuta, Wen Liu, Fei Xing, Hiroshi Okuda, Aya Kobayashi, Kounosuke Watab. RhoC promotes metastasis via activation of the Pyk2 pathway in prostate cancer. Cancer research. vol 68. issue 18. 2008-10-14. PMID:18794150. |
we also found that rhoc significantly augmented the invasion and motility of prostate tumor cells by activating matrix metalloproteinases 2 and 9 (mmp2 and mmp9) in vitro. |
2008-10-14 |
2023-08-12 |
mouse |
| Conrad P Hodgkinson, Kunal Patel, Shu Y. Functional Toll-like receptor 4 mutations modulate the response to fibrinogen. Thrombosis and haemostasis. vol 100. issue 2. 2008-10-08. PMID:18690351. |
the net effect of this signalling pathway was a pro-inflammatory response characterised by il6 and tnfalpha synthesis and increased il8, matrix metalloproteinase (mmp)1, mmp9, and mcp-1 promoter activity. |
2008-10-08 |
2023-08-12 |
human |
| Urara Tamahashi, Jiro Kumagai, Touichiro Takizawa, Masaki Sekine, Yoshinobu Eish. Expression and intracellular localization of matrix metalloproteinases in intraductal papillary mucinous neoplasms of the pancreas. Virchows Archiv : an international journal of pathology. vol 453. issue 1. 2008-09-19. PMID:18500535. |
to analyze the expression of matrix metalloproteinases (mmps) and their relationships with the histological grades of the intraductal papillary mucinous neoplasm (ipmn) of the pancreas, we examined the frequency of expression and intracellular localization of mmp1, mmp2, mmp3, mmp7, and mmp9 in ipmn by immunohistochemistry. |
2008-09-19 |
2023-08-12 |
Not clear |
| Penghua Wang, Jianfeng Dai, Fengwei Bai, Kok-Fai Kong, Susan J Wong, Ruth R Montgomery, Joseph A Madri, Erol Fikri. Matrix metalloproteinase 9 facilitates West Nile virus entry into the brain. Journal of virology. vol 82. issue 18. 2008-09-18. PMID:18632868. |
here we show that matrix metalloproteinase 9 (mmp9) is involved in wnv entry into the brain by enhancing blood-brain barrier permeability. |
2008-09-18 |
2023-08-12 |
mouse |