| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eva Persson, Jörgen Henriksson, Hans Tjälv. Uptake of cobalt from the nasal mucosa into the brain via olfactory pathways in rats. Toxicology letters. vol 145. issue 1. 2003-10-31. PMID:12962970. |
we propose that inhaled hard metal (as a dust powder or in a mist form) is deposited in the nasal passages and that released cobalt, after uptake into the brain via the olfactory pathway, may cause neurotoxicity. |
2003-10-31 |
2023-08-12 |
rat |
| Eva Persson, Jörgen Henriksson, Jonas Tallkvist, Claude Rouleau, Hans Tjälv. Transport and subcellular distribution of intranasally administered zinc in the olfactory system of rats and pikes. Toxicology. vol 191. issue 2-3. 2003-10-28. PMID:12965113. |
administration of 65zn(2+) in the nasal cavity of rats or the olfactory chambers in pikes resulted in an uptake of the metal in the olfactory epithelium and a transport of the metal along the primary olfactory neurons to their terminations in the olfactory bulbs. |
2003-10-28 |
2023-08-12 |
rat |
| Ying Chen, Yi-Qing Liu, Ting Su, Xiang Ren, Li Shi, Dazi Liu, Jun Gu, Qing-Yu Zhang, Xinxin Din. Immunoblot analysis and immunohistochemical characterization of CYP2A expression in human olfactory mucosa. Biochemical pharmacology. vol 66. issue 7. 2003-10-24. PMID:14505803. |
in adults, immunoblot analysis detected cyp2a proteins in microsomes of the olfactory region from 8 of 10 individuals, but in none of the nasal microsomes of the respiratory region from 47 patients. |
2003-10-24 |
2023-08-12 |
human |
| Franck Lemiale, Wing-pui Kong, Levent M Akyürek, Xu Ling, Yue Huang, Bimal K Chakrabarti, Michael Eckhaus, Gary J Nabe. Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system. Journal of virology. vol 77. issue 18. 2003-10-23. PMID:12941918. |
biodistribution of recombinant adenovirus (radv) vectors administered intranasally revealed infection of the central nervous system, specifically in the olfactory bulb, possibly via retrograde transport by olfactory neurons in the nasal epithelium, which may limit the utility of this route of delivery of adv vector-based vaccines. |
2003-10-23 |
2023-08-12 |
mouse |
| Nadezhda Galeva, Dmitry Yakovlev, Yakov Koen, Tatyana Duzhak, Michail Alterma. Direct identification of cytochrome P450 isozymes by matrix-assisted laser desorption/ionization time of flight-based proteomic approach. Drug metabolism and disposition: the biological fate of chemicals. vol 31. issue 4. 2003-10-20. PMID:12642458. |
we have found that cyp2a10 previously reported only in rabbit olfactory and respiratory nasal mucosa is present in phenobarbital (pb)-induced rabbit liver microsomes. |
2003-10-20 |
2023-08-12 |
rat |
| Rachelle M Belanger, Cortney M Smith, Lynda D Corkum, Barbara S Zielinsk. Morphology and histochemistry of the peripheral olfactory organ in the round goby, Neogobius melanostomus (Teleostei: Gobiidae). Journal of morphology. vol 257. issue 1. 2003-10-15. PMID:12740897. |
the olfactory chamber contains a single olfactory lamella; prominent dorsocaudal lachrymal and ethmoidal accessory nasal sacs are situated ventrocaudal to the chamber. |
2003-10-15 |
2023-08-12 |
Not clear |
| Daiji Kagawa, Hiroko Jokura, Ryuji Ochiai, Ichiro Tokimitsu, Hirokazu Tsubon. The sedative effects and mechanism of action of cedrol inhalation with behavioral pharmacological evaluation. Planta medica. vol 69. issue 7. 2003-10-06. PMID:12898420. |
to investigate whether cedrol, which has a very faint aroma, affects the olfactory system, the nasal cavities of wistar rats were treated with zinc sulfate to reduce olfactory function. |
2003-10-06 |
2023-08-12 |
mouse |
| Mukaddes Eşrefoğlu, Erol Selimoğlu, Muammer Eşrefoğlu, Ozgen Vurale. The influence of cigarette smoke on the epithelium of the vestibule: an electron microscopic study. Yonsei medical journal. vol 44. issue 4. 2003-10-02. PMID:12950128. |
it is known that cigarette smoke induces cytological alterations on the respiratory and olfactory mucosa of the nasal cavity. |
2003-10-02 |
2023-08-12 |
Not clear |
| J W Witkin, D Dao, I Livne, I C Dunn, X L Zhou, K Pula, A J Silverma. Early expression of chicken gonadotropin-releasing hormone-1 in the developing chick. Journal of neuroendocrinology. vol 15. issue 9. 2003-10-01. PMID:12899681. |
the expression was subsequently restricted to a narrow, clearly defined region, which is associated with the presumptive nasal cavity and olfactory placode. |
2003-10-01 |
2023-08-12 |
chicken |
| Alison J Vigers, Bärbel Böttger, Zachary C Baquet, Thomas E Finger, Kevin R Jone. Neurotrophin-3 is expressed in a discrete subset of olfactory receptor neurons in the mouse. The Journal of comparative neurology. vol 463. issue 2. 2003-09-26. PMID:12815759. |
during embryonic and early postnatal development, beta-galactosidase is detected in the olfactory system, beginning at embryonic day 11.5 in the nasal epithelium and at embryonic day 16.5 in the olfactory bulb. |
2003-09-26 |
2023-08-12 |
mouse |
| Xinxin Ding, Laurence S Kaminsk. Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. Annual review of pharmacology and toxicology. vol 43. 2003-09-09. PMID:12171978. |
this review focuses on xenobiotic-metabolizing cyps of the human respiratory and gastrointestinal tracts, including the lung, trachea, nasal respiratory and olfactory mucosa, esophagus, stomach, small intestine, and colon. |
2003-09-09 |
2023-08-12 |
human |
| John D Hooper, Luisa Campagnolo, Goodarz Goodarzi, Tony N Truong, Heidi Stuhlmann, James P Quigle. Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues. The Biochemical journal. vol 373. issue Pt 3. 2003-09-03. PMID:12744720. |
while m-hepsin was detected in the residual embryonic yolk sac and with lower intensity in lung, heart, gastrointestinal tract, developing kidney tubules and epithelium of the oral cavity, m-matriptase-2 was absent in these tissues, but strongly expressed within the nasal cavity by olfactory epithelial cells. |
2003-09-03 |
2023-08-12 |
mouse |
| Fumihiko Kitamura, Kazuhito Yokoyama, Shunichi Araki, Mariko Nishikitani, Jae-Wook Choi, Youg-Tae Yum, Hee-Chan Park, Sang-Hwoi Park, Hajime Sat. Increase of olfactory threshold in plating factory workers exposed to chromium in Korea. Industrial health. vol 41. issue 3. 2003-08-29. PMID:12916760. |
to disclose the effects of chromium (cr) on olfactory function, olfactory threshold tests were conducted on 27 male plating workers (cr workers) with signs and symptoms of olfactory irritation but without nasal septum perforation or ulcer and on 34 male control subjects in korean plating factories. |
2003-08-29 |
2023-08-12 |
human |
| Fumihiko Kitamura, Kazuhito Yokoyama, Shunichi Araki, Mariko Nishikitani, Jae-Wook Choi, Youg-Tae Yum, Hee-Chan Park, Sang-Hwoi Park, Hajime Sat. Increase of olfactory threshold in plating factory workers exposed to chromium in Korea. Industrial health. vol 41. issue 3. 2003-08-29. PMID:12916760. |
olfactory thresholds were not significantly different between the cr workers with and without nasal signs or symptoms, except that the scores on the recognition threshold were significantly higher in those experiencing difficulty with smell (p < 0.05). |
2003-08-29 |
2023-08-12 |
human |
| Fumihiko Kitamura, Kazuhito Yokoyama, Shunichi Araki, Mariko Nishikitani, Jae-Wook Choi, Youg-Tae Yum, Hee-Chan Park, Sang-Hwoi Park, Hajime Sat. Increase of olfactory threshold in plating factory workers exposed to chromium in Korea. Industrial health. vol 41. issue 3. 2003-08-29. PMID:12916760. |
it is suggested that olfactory threshold is affected by cr without development of nasal septum perforation or ulceration. |
2003-08-29 |
2023-08-12 |
human |
| P Larsson, E Persson, E Tydén, H Tjälv. Cell-specific activation of aflatoxin B1 correlates with presence of some cytochrome P450 enzymes in olfactory and respiratory tissues in horse. Research in veterinary science. vol 74. issue 3. 2003-07-30. PMID:12726741. |
the results showed covalent binding of afb(1)-metabolites in sustentacular cells and cells of bowman's glands in the olfactory mucosa, in some cells of the surface epithelium of nasal respiratory, tracheal, bronchial and bronchiolar mucosa and in some glands in these areas. |
2003-07-30 |
2023-08-12 |
Not clear |
| Christopher Hawke. Olfaction in neurodegenerative disorder. Movement disorders : official journal of the Movement Disorder Society. vol 18. issue 4. 2003-07-28. PMID:12671941. |
biopsy of olfactory nasal neurons shows non-specific changes in pd and ad and at present will not aid diagnosis. |
2003-07-28 |
2023-08-12 |
human |
| Heider Lopes de Souza, Ana Maria de Oliveira Ramos, Carlos Cesar Formiga Ramos, Syomara Pereira da Costa Melo, Hougelle Simplício Gomes Pereira, João Flávio Gurjão Madureira, Janaína Martins de Lan. [Olfactory groove schwannoma: case report]. Arquivos de neuro-psiquiatria. vol 61. issue 1. 2003-06-04. PMID:12715036. |
one month later, ct demonstrated a homogeneously contrast-enhancing mass in the olfactory groove region who extended into the left nasal cavity. |
2003-06-04 |
2023-08-12 |
Not clear |
| G BARTALEN. [Olfaction in anosmic; experiments designed to demonstrate value of the nasal cavity as a biochemical olfactory laboratory]. Bollettino delle malattie dell'orecchio, della gola, del naso. vol 71. issue 2. 2003-05-01. PMID:13105852. |
[olfaction in anosmic; experiments designed to demonstrate value of the nasal cavity as a biochemical olfactory laboratory]. |
2003-05-01 |
2023-08-12 |
Not clear |
| G FALE. [Olfactory and nasal changes in Paget's osteitis deformans]. L'Oto-rino-laringologia italiana. vol 22. issue 3. 2003-05-01. PMID:13203986. |
[olfactory and nasal changes in paget's osteitis deformans]. |
2003-05-01 |
2023-08-12 |
Not clear |